Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Kevin W Kelley, Omer Revah, Felicity Gore, Konstantin Kaganovsky, Xiaoyu Chen, Karl Deisseroth, Sergiu P Pașc. Host circuit engagement of human cortical organoids transplanted in rodents. Nature protocols. 2024-07-29. PMID:39075308. |
here, we describe a method for transplanting human stem cell-derived cortical organoids (hcos) into the somatosensory cortex of newborn rats. |
2024-07-29 |
2024-08-02 |
human |
Erin M Hurley, Pawel Mozolewski, Radek Dobrowolski, Jenny Hsie. Familial Alzheimer's disease-associated PSEN1 mutations affect neurodevelopment through increased Notch signaling. Stem cell reports. 2023-06-23. PMID:37352850. |
while rodent models are useful for modeling later stages of ad, human induced pluripotent stem cell-derived cortical spheroids (hcss) allow access to studying the human cortex at the cellular level over the course of development. |
2023-06-23 |
2023-08-14 |
human |
Sara Palma-Tortosa, Raquel Martínez-Curiel, Constanza Aretio-Medina, Natalia Avaliani, Zaal Kokai. Organotypic Cultures of Adult Human Cortex as an Ex vivo Model for Human Stem Cell Transplantation and Validation. Journal of visualized experiments : JoVE. issue 190. 2022-12-26. PMID:36571400. |
this method combines long-term organotypic cultures of the adult human cortex, obtained from epileptic patients undergoing resective surgery, and ex vivo intracortical transplantation of induced pluripotent stem cell-derived cortical progenitors. |
2022-12-26 |
2023-08-14 |
human |
Matthieu Genestine, Daisy Ambriz, Gregg W Crabtree, Patrick Dummer, Anna Molotkova, Michael Quintero, Angeliki Mela, Saptarshi Biswas, Huijuan Feng, Chaolin Zhang, Peter Canoll, Gunnar Hargus, Dritan Agalliu, Joseph A Gogos, Edmund A. Vascular-derived SPARC and SerpinE1 regulate interneuron tangential migration and accelerate functional maturation of human stem cell-derived interneurons. eLife. vol 10. 2021-10-27. PMID:33904394. |
moreover, pre-treatment of human stem cell-derived interneurons (hsc-interneurons) with sparc and serpine1 prior to transplantation into neonatal mouse cortex enhanced their migration and morphological elaboration in the host cortex. |
2021-10-27 |
2023-08-13 |
mouse |
Rosalind S E Carne. Transplanted Human Induced Pluripotent Stem Cell-Derived Neurons Wire and Fire with Balanced Excitation-Inhibition in Rat Cortex. eNeuro. vol 7. issue 2. 2021-06-18. PMID:32299834. |
transplanted human induced pluripotent stem cell-derived neurons wire and fire with balanced excitation-inhibition in rat cortex. |
2021-06-18 |
2023-08-13 |
human |
Jean-Pyo Lee, Runquan Zhang, Maocai Yan, Srinivas Duggineni, Dustin R Wakeman, Walter L Niles, Yongmei Feng, Justin Chen, Milton H Hamblin, Edward B Han, Rodolfo Gonzalez, Xiao Fang, Yinsong Zhu, Juan Wang, Yan Xu, David A Wenger, Thomas N Seyfried, Jing An, Richard L Sidman, Ziwei Huang, Evan Y Snyde. Chemical mutagenesis of a GPCR ligand: Detoxifying "inflammo-attraction" to direct therapeutic stem cell migration. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 49. 2021-01-29. PMID:33219123. |
when co-administered with transplanted human induced pluripotent stem cell-derived hnscs in a mouse model of a prototypical neurodegenerative disease, the agonist enhanced migration, dissemination, and integration of donor-derived cells into the diseased cerebral cortex (including as electrophysiologically-active cortical neurons) where their secreted cross-corrective enzyme mediated a therapeutic impact unachieved by cells alone. |
2021-01-29 |
2023-08-13 |
mouse |
Tasuku Kayama, Kazuki Okamoto, Mengxuan Gao, Yuji Ikegaya, Takuya Sasak. Immature electrophysiological properties of human-induced pluripotent stem cell-derived neurons transplanted into the mouse cortex for 7 weeks. Neuroreport. vol 30. issue 3. 2019-12-26. PMID:30557202. |
immature electrophysiological properties of human-induced pluripotent stem cell-derived neurons transplanted into the mouse cortex for 7 weeks. |
2019-12-26 |
2023-08-13 |
mouse |
Tomasz J Nowakowski, Alex A Pollen, Elizabeth Di Lullo, Carmen Sandoval-Espinosa, Marina Bershteyn, Arnold R Kriegstei. Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells. Cell stem cell. vol 18. issue 5. 2017-07-19. PMID:27038591. |
we also show that axl expression in radial glia is conserved in developing mouse and ferret cortex and in human stem cell-derived cerebral organoids, highlighting multiple experimental systems that could be applied to study mechanisms of zikv infectivity and effects on brain development. |
2017-07-19 |
2023-08-13 |
mouse |
Ya Zhou, Katarzyna Falenta, Giovanna Lall. Endocannabinoid signalling in neuronal migration. The international journal of biochemistry & cell biology. vol 47. 2014-11-06. PMID:24361301. |
indeed, ecb signalling controls migration both pre- and post-natally, regulating interneuron positioning in the developing cortex and hippocampus and the polarised motility of stem cell-derived neuroblasts. |
2014-11-06 |
2023-08-12 |
Not clear |
Daniel Tornero, Somsak Wattananit, Marita Grønning Madsen, Philipp Koch, James Wood, Jemal Tatarishvili, Yutaka Mine, Ruimin Ge, Emanuela Monni, Karthikeyan Devaraju, Robert F Hevner, Oliver Brüstle, Olle Lindvall, Zaal Kokai. Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery. Brain : a journal of neurology. vol 136. issue Pt 12. 2014-02-10. PMID:24148272. |
human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery. |
2014-02-10 |
2023-08-12 |
human |
Makoto Ideguchi, Theo D Palmer, Lawrence D Recht, James M Weiman. Murine embryonic stem cell-derived pyramidal neurons integrate into the cerebral cortex and appropriately project axons to subcortical targets. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 3. 2010-02-05. PMID:20089898. |
murine embryonic stem cell-derived pyramidal neurons integrate into the cerebral cortex and appropriately project axons to subcortical targets. |
2010-02-05 |
2023-08-12 |
Not clear |
S Arnhold, A Fassbender, F-J Klinz, K Kruttwig, B Löhnig, C Andressen, K Addick. NOS-II is involved in early differentiation of murine cortical, retinal and ES cell-derived neurons-an immunocytochemical and functional approach. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 20. issue 2. 2002-08-28. PMID:12034139. |
in a pharmacological approach using cultures of the mouse cortex as well as embryonic stem cell-derived neural precursor cells, we investigated the functional role of no on initial neuronal differentiation. |
2002-08-28 |
2023-08-12 |
mouse |