| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yanhai Kang, Li Sheng, Jia L. HINT1 promotes neuronal apoptosis and triggers schizophrenia-like behavior in rats. Behavioural brain research. 2024-10-19. PMID:39426527. |
we also created a hint1 overexpression model in hippocampal neuronal cells to analyze its effects on cell proliferation and apoptosis. |
2024-10-19 |
2024-10-22 |
rat |
| Seyede-Mojdeh Safavi-Naeini, Mohammad Nasehi, Mohammad-Reza Zarrindast, Seyed-Abbas Safavi-Naein. Exploring the effects of naringenin on cell functioning and energy synthesis in the hippocampus of male Wistar rats with chronic tinnitus, by examining genetic indicators such as Bax, Bcl-2, Tfam, and Pgc-1α. Gene. 2024-10-05. PMID:39368787. |
exploring the effects of naringenin on cell functioning and energy synthesis in the hippocampus of male wistar rats with chronic tinnitus, by examining genetic indicators such as bax, bcl-2, tfam, and pgc-1α. |
2024-10-05 |
2024-10-08 |
rat |
| Kari R Hoyt, Paul Horning, Pia Georgette Ang, Kate Karelina, Karl Obrieta. Ribosomal S6 Kinase signaling regulates neuronal viability during development and confers resistance to excitotoxic cell death in mature neurons. Neuroscience. 2024-08-13. PMID:39137868. |
in maturing hippocampal explant cultures, treatment with bid1870 had minimal effects on cell viability, but led to a striking augmentation of nmda-induced cell death. |
2024-08-13 |
2024-08-16 |
Not clear |
| Abudurousuli Adili, Aerken Dilihumaer, Huhu Zhu, Huifang Tan. Research progress on phosphodiesterase 4 inhibitors in central nervous system diseases. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. 2024-06-11. PMID:38860393. |
pde4 inhibitors have long-term potentiation effect, which can enhance phosphorylation of camp response element binding protein (creb) and upregulate expression of memory related arc genes in hippocampal neurons, thereby improving cognitive impairment and alzheimer's disease-like symptoms; and also resist the occurrence and development of parkinson's disease by reducing the cytotoxicity induced by α-syn and increasing the effect of mir-124-3p on cell activity. |
2024-06-11 |
2024-06-14 |
Not clear |
| Barbara Canonico, Silvia Carloni, Mariele Montanari, Patrizia Ambrogini, Stefano Papa, Daniel Alonso-Alconada, Walter Balduin. Melatonin Modulates Cell Cycle Dynamics and Promotes Hippocampal Cell Proliferation After Ischemic Injury in Neonatal Rats. Molecular neurobiology. 2024-02-15. PMID:38358438. |
the present study aimed to assess the effects of melatonin on cell proliferation after an ischemic injury in the developing hippocampus, focusing on cell cycle dynamics. |
2024-02-15 |
2024-02-17 |
rat |
| J O Kim, D Y Jung, B I Mi. Avocado Peel Extract: The effect of radiation-induced on neuroanatomical and behavioral changes in rats. Journal of chemical neuroanatomy. 2023-02-04. PMID:36738850. |
in the future, based on these results, we will conduct research on the hippocampus and amygdala, which are major regions of the brain, and additional research on cell biology. |
2023-02-04 |
2023-08-14 |
rat |
| Cora Olpe, Sebastian Jessberge. Cell population dynamics in the course of adult hippocampal neurogenesis: Remaining unknowns. Hippocampus. 2022-10-18. PMID:36256493. |
then, we outline the current knowledge on cell integration dynamics, discussing which (if any) neurons are replaced by newly added neurons in the hippocampal circuits. |
2022-10-18 |
2023-08-14 |
Not clear |
| Caitlin P Mencio, Sharada M Tilve, Masato Suzuki, Kohei Higashi, Yasuhiro Katagiri, Herbert M Gelle. A novel cytoskeletal action of xylosides. PloS one. vol 17. issue 6. 2022-06-28. PMID:35763520. |
to our surprise, we found that concentrations of xylosides in the nanomolar to micromolar range had major effects on cell morphology of hippocampal neurons as well as of neuro2a cells, affecting both actin and tubulin cytoskeletal dynamics. |
2022-06-28 |
2023-08-14 |
Not clear |
| Hannah S Wirtshafter, John F Disterhof. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-05-02. PMID:35501152. |
because the hippocampus (hpc) is essential for tasks of memory, spatial navigation, and learning, calcium imaging of large populations of hpc neurons can provide new insight on cell changes over time during these tasks. |
2022-05-02 |
2023-08-13 |
mouse |
| Jeffrey Farooq, Kara Snyder, Keri Janesko-Feldman, Kiersten Gorse, Vincent Vagni, Patrick M Kochanek, Travis C Jackso. RNA Binding Motif 5 Gene Deletion Modulates Cell Signaling in a Sex-Dependent Manner but not Hippocampal Cell Death. Journal of neurotrauma. 2022-02-14. PMID:35152732. |
finally, gene analysis revealed increased estrogen receptor α (erα) levels in the ko hippocampus in females and may suggest a novel mechanism to explain sex-dimorphic effects on cell signaling. |
2022-02-14 |
2023-08-13 |
mouse |
| Agnieszka Wąsik, Magdalena Białoń, Danuta Jantas, Marcelina Żarnowsk. The Impact of the Combined Administration of 1MeTIQ and MK-801 on Cell Viability, Oxidative Stress Markers, and Glutamate Release in the Rat Hippocampus. Neurotoxicity research. vol 39. issue 6. 2021-12-04. PMID:34665405. |
the impact of the combined administration of 1metiq and mk-801 on cell viability, oxidative stress markers, and glutamate release in the rat hippocampus. |
2021-12-04 |
2023-08-13 |
rat |
| Agnieszka Wąsik, Magdalena Białoń, Danuta Jantas, Marcelina Żarnowsk. The Impact of the Combined Administration of 1MeTIQ and MK-801 on Cell Viability, Oxidative Stress Markers, and Glutamate Release in the Rat Hippocampus. Neurotoxicity research. vol 39. issue 6. 2021-12-04. PMID:34665405. |
the aim of the present study was to evaluate the effect of combined treatment with 1metiq and mk-801 on cell viability, antioxidant enzyme activity, and glutamate release in the rat hippocampus. |
2021-12-04 |
2023-08-13 |
rat |
| Alish B Palmos, Rodrigo R R Duarte, Demelza M Smeeth, Erin C Hedges, Douglas F Nixon, Sandrine Thuret, Timothy R Powel. Lithium treatment and human hippocampal neurogenesis. Translational psychiatry. vol 11. issue 1. 2021-11-17. PMID:34718328. |
here, we tested the chronic effects of low (0.75 mm) and high (2.25 mm) doses of lithium on human hippocampal progenitor cells and used immunocytochemistry to investigate the effects of lithium on cell parameters implicated in neurogenesis. |
2021-11-17 |
2023-08-13 |
human |
| Timothy J Schoenfeld, Chance Swanso. A Runner's High for New Neurons? Potential Role for Endorphins in Exercise Effects on Adult Neurogenesis. Biomolecules. vol 11. issue 8. 2021-09-27. PMID:34439743. |
this includes possible routes for beta-endorphin signaling into the hippocampus during exercise, direct effects of beta-endorphin on cell proliferation and neurogenesis, and behavioral effects of manipulating endogenous opioid signaling. |
2021-09-27 |
2023-08-13 |
Not clear |
| Soo Jung Shin, Yunkwon Nam, Yong Ho Park, Min-Jeong Kim, Eunbeen Lee, Seong Gak Jeon, Bong-Seok Bae, Jiho Seo, Sung-Lye Shim, Jong-Seok Kim, Chang-Kyun Han, Sujin Kim, Yong Yook Lee, Minho Moo. Therapeutic effects of non-saponin fraction with rich polysaccharide from Korean red ginseng on aging and Alzheimer's disease. Free radical biology & medicine. vol 164. 2021-06-24. PMID:33422674. |
next, we investigated (1) the effects of nfp on ad pathologies, such as aβ deposition, neuroinflammation, neurodegeneration, mitochondrial dysfunction, and impaired adult hippocampal neurogenesis (ahn), in 5xfad transgenic mouse model of ad using immunostaining; (2) the effect of nfp on aβ-mediated mitochondrial respiration deficiency in ht22 mouse hippocampal neuronal cells (ht22) using seahorse xfp analysis; (3) the effect of nfp on cell proliferation using wst-1 analysis; and (4) the effect of nfp on aβ-induced cognitive dysfunction in 5xfad mouse model of ad using y-maze test. |
2021-06-24 |
2023-08-13 |
mouse |
| Xiaodong Xu, Guohua Wu, Yong Liu, Liangcheng Zhan. Effects of propofol on hippocampal neuron viability. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. vol 36. issue 9. 2021-06-21. PMID:32179983. |
in this study, we investigated the effects of different concentration of propofol on cell viability of hippocampal neurons and explored the possible mechanism. |
2021-06-21 |
2023-08-13 |
Not clear |
| Anggraeini Puspitasari, Hiroyuki Yamazaki, Hidemasa Kawamura, Takashi Nakano, Akihisa Takahashi, Tomoaki Shirao, Kathryn D Hel. X-irradiation of developing hippocampal neurons causes changes in neuron population phenotypes, dendritic morphology and synaptic protein expression in surviving neurons at maturity. Neuroscience research. vol 160. 2021-05-14. PMID:31711782. |
we used primary cultures of mouse hippocampal neurons to investigate the effects of x-irradiation on cell death in developing neurons by analyzing caspase-3, map2 and dapi-labeled cells, and the phenotypes and function of surviving neurons, by examining gad67-positive cells as a gabaergic marker, and the synaptic markers synapsin 1, drebrin and psd-95 through its maturation. |
2021-05-14 |
2023-08-13 |
mouse |
| Steffen Mayerl, Heike Heuer, Charles Ffrench-Constan. Hippocampal Neurogenesis Requires Cell-Autonomous Thyroid Hormone Signaling. Stem cell reports. vol 14. issue 5. 2021-04-16. PMID:32302557. |
together, our results reveal a cell-autonomous role for th signaling in adult hippocampal neurogenesis alongside non-cell-autonomous effects on cell proliferation earlier in the lineage. |
2021-04-16 |
2023-08-13 |
mouse |
| Thuy Trang Nguyen, Qui Thanh Hoai Ta, Thi Thuy Dung Nguyen, Thi Thuy Le, Van Giau V. Role of Insulin Resistance in the Alzheimer's Disease Progression. Neurochemical research. vol 45. issue 7. 2021-03-29. PMID:32314178. |
insulin resistance or dysfunction of insulin signaling is a universal feature of t2d, the main culprit for altered glucose metabolism and its interdependence on cell death pathways, forming the basis of linking t2d with ad as it may exacerbate aβ accumulation, tau hyperphosphorylation and devastates glucose transportation, energy metabolism, hippocampal framework and promulgate inflammatory pathways. |
2021-03-29 |
2023-08-13 |
Not clear |
| Jude Prah, Ali Winters, Kiran Chaudhari, Jessica Hersh, Ran Liu, Shao-Hua Yan. Cholesterol sulfate alters astrocyte metabolism and provides protection against oxidative stress. Brain research. vol 1723. 2020-10-27. PMID:31425677. |
the neuroprotective effect of cs and its role on cell metabolism were determined in primary astrocyte prepared from the cortex of postnatal day 0-2 c57bl/6 pups and a hippocampal ht-22 cell line using calcein am and mtt cell viability assay, flow cytometry, seahorse extracellular flux analysis, and metabolism assay kits. |
2020-10-27 |
2023-08-13 |
human |