| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuan Yao, Jingyi Du, Dongshuang Wang, Naigang Li, Zhouhang Tao, Dong Wu, Fan Peng, Jiaming Shi, Wenjuan Zhou, Tiantian Zhao, Yuchun Tan. High-intensity interval training ameliorates postnatal immune activation-induced mood disorders through KDM6B-regulated glial activation. Brain, behavior, and immunity. 2024-06-08. PMID:38851307. |
rna-seq of prefrontal cortex (pfc) tissues revealed a gene expression pattern, confirming that hiit was more effective than mict in improving brain glial cell activation through epigenetic modifications of kdm6b. |
2024-06-08 |
2024-06-11 |
mouse |
| Samir Rahman, Pengfei Dong, Pasha Apontes, Michael B Fernando, Roman Kosoy, Kayla G Townsley, Kiran Girdhar, Jaroslav Bendl, Zhiping Shao, Ruth Misir, Nadia Tsankova, Steven P Kleopoulos, Kristen J Brennand, John F Fullard, Panos Rousso. Lineage specific 3D genome structure in the adult human brain and neurodevelopmental changes in the chromatin interactome. Nucleic acids research. 2023-10-09. PMID:37811875. |
to decipher cell type specific genome architecture, and characterize fine scale changes in the chromatin interactome across neural development, we compared the 3d genome of the human fetal cortical plate to that of neurons and glia isolated from the adult prefrontal cortex. |
2023-10-09 |
2023-10-15 |
human |
| Nour-Eddine Kaikai, Saadia Ba-M'hamed, Abderrazzak Ghanima, Mohamed Benni. Exposure to metam sodium-based pesticide impaired cognitive performances in adult mice: Involvement of oxidative damage and glial activation. Toxicology and applied pharmacology. 2023-09-07. PMID:37678439. |
moreover, exposure to ms-bp is associated with a significant rise in the density of astrocytic and microglial markers, indicating a possible glial cell response within the prefrontal cortex and hippocampus. |
2023-09-07 |
2023-10-07 |
mouse |
| Lianwei Mu, Dongdong Xia, Jiajia Cai, Boya Gu, Xiaojie Liu, Vladislav Friedman, Qing-Song Liu, Li Zha. Treadmill Exercise Reduces Neuroinflammation, Glial Cell Activation and Improves Synaptic Transmission in the Prefrontal Cortex in 3 × Tg-AD Mice. International journal of molecular sciences. vol 23. issue 20. 2022-10-27. PMID:36293516. |
treadmill exercise reduces neuroinflammation, glial cell activation and improves synaptic transmission in the prefrontal cortex in 3 × tg-ad mice. |
2022-10-27 |
2023-08-14 |
mouse |
| Lianwei Mu, Dongdong Xia, Jiajia Cai, Boya Gu, Xiaojie Liu, Vladislav Friedman, Qing-Song Liu, Li Zha. Treadmill Exercise Reduces Neuroinflammation, Glial Cell Activation and Improves Synaptic Transmission in the Prefrontal Cortex in 3 × Tg-AD Mice. International journal of molecular sciences. vol 23. issue 20. 2022-10-27. PMID:36293516. |
here, we test the hypothesis that aβ oligomer accumulation, neuroinflammation, and glial cell activation may lead to disruption of synaptic transmission in the prefrontal cortex of 3 × tg-ad mice, resulting in impairment of learning and memory. |
2022-10-27 |
2023-08-14 |
mouse |
| Lianwei Mu, Dongdong Xia, Jiajia Cai, Boya Gu, Xiaojie Liu, Vladislav Friedman, Qing-Song Liu, Li Zha. Treadmill Exercise Reduces Neuroinflammation, Glial Cell Activation and Improves Synaptic Transmission in the Prefrontal Cortex in 3 × Tg-AD Mice. International journal of molecular sciences. vol 23. issue 20. 2022-10-27. PMID:36293516. |
thus, treadmill exercise reduces neuroinflammation, glial cell activation and improves synaptic transmission in the prefrontal cortex in 3 × tg-ad mice, possibly related to the inhibition of gsk3β kinase activity. |
2022-10-27 |
2023-08-14 |
mouse |
| Chuan-Xi Tang, Jing Chen, Kai-Quan Shao, Ye-Hao Liu, Xiao-Yu Zhou, Cheng-Cheng Ma, Meng-Ting Liu, Ming-Yu Shi, Piniel Alphayo Kambey, Wei Wang, Abiola Abdulrahman Ayanlaja, Yi-Fang Liu, Wei Xu, Gang Chen, Jiao Wu, Xue Li, Dian-Shuai Ga. Blunt dopamine transmission due to decreased GDNF in the PFC evokes cognitive impairment in Parkinson's disease. Neural regeneration research. vol 18. issue 5. 2022-10-18. PMID:36255000. |
we then established a mouse model of parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and analyzed the potential relationships among glial cell line-derived neurotrophic factor in the prefrontal cortex, dopamine transmission, and cognitive function. |
2022-10-18 |
2023-08-14 |
mouse |
| Chuan-Xi Tang, Jing Chen, Kai-Quan Shao, Ye-Hao Liu, Xiao-Yu Zhou, Cheng-Cheng Ma, Meng-Ting Liu, Ming-Yu Shi, Piniel Alphayo Kambey, Wei Wang, Abiola Abdulrahman Ayanlaja, Yi-Fang Liu, Wei Xu, Gang Chen, Jiao Wu, Xue Li, Dian-Shuai Ga. Blunt dopamine transmission due to decreased GDNF in the PFC evokes cognitive impairment in Parkinson's disease. Neural regeneration research. vol 18. issue 5. 2022-10-18. PMID:36255000. |
our results showed that decreased glial cell line-derived neurotrophic factor in the prefrontal cortex weakened dopamine release and transmission by upregulating the presynaptic membrane expression of the dopamine transporter, which led to the loss and primitivization of dendritic spines of pyramidal neurons and cognitive impairment. |
2022-10-18 |
2023-08-14 |
mouse |
| Chuan-Xi Tang, Jing Chen, Kai-Quan Shao, Ye-Hao Liu, Xiao-Yu Zhou, Cheng-Cheng Ma, Meng-Ting Liu, Ming-Yu Shi, Piniel Alphayo Kambey, Wei Wang, Abiola Abdulrahman Ayanlaja, Yi-Fang Liu, Wei Xu, Gang Chen, Jiao Wu, Xue Li, Dian-Shuai Ga. Blunt dopamine transmission due to decreased GDNF in the PFC evokes cognitive impairment in Parkinson's disease. Neural regeneration research. vol 18. issue 5. 2022-10-18. PMID:36255000. |
in addition, magnetic resonance imaging data showed that the long-term lack of glial cell line-derived neurotrophic factor reduced the connectivity between the prefrontal cortex and other brain regions, and exogenous glial cell line-derived neurotrophic factor significantly improved this connectivity. |
2022-10-18 |
2023-08-14 |
mouse |
| Chuan-Xi Tang, Jing Chen, Kai-Quan Shao, Ye-Hao Liu, Xiao-Yu Zhou, Cheng-Cheng Ma, Meng-Ting Liu, Ming-Yu Shi, Piniel Alphayo Kambey, Wei Wang, Abiola Abdulrahman Ayanlaja, Yi-Fang Liu, Wei Xu, Gang Chen, Jiao Wu, Xue Li, Dian-Shuai Ga. Blunt dopamine transmission due to decreased GDNF in the PFC evokes cognitive impairment in Parkinson's disease. Neural regeneration research. vol 18. issue 5. 2022-10-18. PMID:36255000. |
these findings suggested that decreased glial cell line-derived neurotrophic factor in the prefrontal cortex leads to neuroplastic degeneration at the level of synaptic connections and circuits, which results in cognitive impairment in patients with parkinson's disease. |
2022-10-18 |
2023-08-14 |
mouse |
| Sierra M Webb, Arianne D Sacramento, Megan A McCloskey, Melissa G Wroten, Kyle L Ploense, Tod E Kippin, Osnat Ben-Shahar, Karen K Szumlinsk. The incubation of cocaine craving is dissociated from changes in glial cell markers within prefrontal cortex and nucleus accumbens of rats. Addiction neuroscience. vol 3. 2022-08-29. PMID:36034166. |
the incubation of cocaine craving is dissociated from changes in glial cell markers within prefrontal cortex and nucleus accumbens of rats. |
2022-08-29 |
2023-08-14 |
rat |
| Sami I Alzarea, Hassan H Alhassan, Abdulaziz I Alzarea, Ziad H Al-Oanzi, Muhammad Afza. Antidepressant-like Effects of Renin Inhibitor Aliskiren in an Inflammatory Mouse Model of Depression. Brain sciences. vol 12. issue 5. 2022-05-28. PMID:35625041. |
therefore, the goal of the current study is to determine the antidepressant-like effects of aliskiren, a renin inhibitor, against lipopolysaccharide (lps)-induced depressive-like behavior in mice, glial cell activation, and the upregulation of proinflammatory cytokines in the prefrontal cortex. |
2022-05-28 |
2023-08-13 |
mouse |
| Ashlyn G Johnson, James A Webster, Chadwick M Hale. Glial profiling of human tauopathy brain demonstrates enrichment of astrocytic transcripts in tau-related frontotemporal degeneration. Neurobiology of aging. vol 112. 2022-01-20. PMID:35051675. |
to understand how glia may be altered in frontotemporal degeneration with tau pathology (ftd-tau), we used a nanostring glial profiling panel to measure 770 transcripts related to glial biology in human control (n = 8), alzheimer's disease (ad) (n = 8), and ftd-tau (n = 8) dorsolateral prefrontal cortex. |
2022-01-20 |
2023-08-13 |
human |
| Xiaoyan Zheng, Wenjia Lin, Yimin Jiang, Kejia Lu, Wenjing Wei, Qingwei Huo, Shaoyang Cui, Xifei Yang, Min Li, Nenggui Xu, Chunzhi Tang, Ju-Xian Son. Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB). Autophagy. vol 17. issue 11. 2021-12-11. PMID:33622188. |
tnea reduced app (amyloid beta (a4) precursor protein), c-terminal fragments (ctfs) of app and aβ load, and inhibited glial cell activation in the prefrontal cortex and hippocampus of 5xfad. |
2021-12-11 |
2023-08-13 |
human |
| I N Bogolepova, L I Malofeeva, P A Agapo. The Brain of an Outstanding Scientist-Inventor: Structural Organization of Area 10 of the Frontal Cortex. Bulletin of experimental biology and medicine. vol 172. issue 1. 2021-11-23. PMID:34792715. |
it was found that the cytoarchitectonic organization of the cortical area 10 of the prefrontal cortex of the brain of an outstanding scientist-inventor is characterized by more pronounced vertical striation, greater thickness of the cortex and association layer iii, higher density and size of pyramid neurons and higher density of satellite glia. |
2021-11-23 |
2023-08-13 |
Not clear |
| Lin Zhang, Ronald W H Verwer, Paul J Lucassen, Inge Huitinga, Dick F Swaa. Sex difference in glia gene expression in the dorsolateral prefrontal cortex in bipolar disorder: Relation to psychotic features. Journal of psychiatric research. vol 125. 2021-05-14. PMID:32208195. |
sex difference in glia gene expression in the dorsolateral prefrontal cortex in bipolar disorder: relation to psychotic features. |
2021-05-14 |
2023-08-13 |
human |
| Lin Zhang, Ronald W H Verwer, Paul J Lucassen, Inge Huitinga, Dick F Swaa. Prefrontal cortex alterations in glia gene expression in schizophrenia with and without suicide. Journal of psychiatric research. vol 121. 2021-03-24. PMID:31739114. |
prefrontal cortex alterations in glia gene expression in schizophrenia with and without suicide. |
2021-03-24 |
2023-08-13 |
Not clear |
| Lin Zhang, Ronald W H Verwer, Paul J Lucassen, Inge Huitinga, Dick F Swaa. Prefrontal cortex alterations in glia gene expression in schizophrenia with and without suicide. Journal of psychiatric research. vol 121. 2021-03-24. PMID:31739114. |
alterations in glia activities in the prefrontal cortex (pfc) have been reported in relation to suicide in patients with scz. |
2021-03-24 |
2023-08-13 |
Not clear |
| Placido Illiano, Damiana Leo, Raul R Gainetdinov, Marta Pard. Early Adolescence Prefrontal Cortex Alterations in Female Rats Lacking Dopamine Transporter. Biomedicines. vol 9. issue 2. 2021-03-16. PMID:33562738. |
we report herein that genetic ablation of dat in the early adolescent pfc of female rats leads to changes in neuronal and glial cell homeostasis. |
2021-03-16 |
2023-08-13 |
human |
| Emma K Erickson, Yuri A Blednov, R Adron Harris, R Dayne Mayfiel. Glial gene networks associated with alcohol dependence. Scientific reports. vol 9. issue 1. 2020-10-27. PMID:31358844. |
we performed rna-sequencing on total homogenate and glial cell populations isolated from mouse prefrontal cortex (pfc) following chronic intermittent ethanol vapor exposure (cie). |
2020-10-27 |
2023-08-13 |
mouse |