| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Roberta Amoriello, Clara Ballerin. Immunofluorescence Staining of Murine Spinal Cord Sections to Evaluate Microglial Activation and Astrogliosis. Methods in molecular biology (Clifton, N.J.). vol 2857. 2024-09-30. PMID:39348064. |
upon activation, microglia is able to phagocyte cell debris, pathogens, and toxins; astrocytes support neuronal functions, blood-brain barrier (bbb) homeostasis, and neurotransmitter uptake and metabolism. |
2024-09-30 |
2024-10-02 |
mouse |
| Eva Šimončičová, Keelin Henderson Pekarik, Haley A Vecchiarelli, Clotilde Lauro, Laura Maggi, Marie-Ève Trembla. Adult Neurogenesis, Learning and Memory. Advances in neurobiology. vol 37. 2024-08-29. PMID:39207695. |
further redefinition of the synapse as 'quad-partite' followed to acknowledge the contribution of microglia which were revealed to affect numerous brain functions via dynamic interactions with synapses, acting as 'synaptic sensors' that respond to neuronal activity and neurotransmitter release, as well as crosstalk with astrocytes. |
2024-08-29 |
2024-09-04 |
Not clear |
| Hui Zhong, Tianshu Liu, You Shang, Chaolin Huang, Shangwen Pa. Breaking the vicious cycle: Targeting the NLRP3 inflammasome for treating sepsis-associated encephalopathy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 177. 2024-07-14. PMID:39004064. |
the pathogenesis of sae is complex, including neuroinflammation and microglia activation, destruction of the blood-brain barrier (bbb), neurotransmitter dysfunction, cerebral metabolism and mitochondrial impairment, accumulation of amyloid beta and tauopathy, complement activation, among others. |
2024-07-14 |
2024-07-18 |
Not clear |
| Yvonne Chen, Julia Mateski, Linda Gerace, Jonathan Wheeler, Jan Burl, Bhavna Prakash, Cherie Svedin, Rebecca Amrick, Brian D Adam. Non-coding RNAs and neuroinflammation: implications for neurological disorders. Experimental biology and medicine (Maywood, N.J.). vol 249. 2024-03-11. PMID:38463392. |
dysregulated mirnas present in the microglia, astrocytes, oligodendrocytes, and epididymal cells, contribute to an overall glial-specific inflammatory niche that impacts the activity of neuronal conductivity, signaling action potentials, neurotransmitter robustness, neuron-neuron specific communication, and neuron-muscular connections. |
2024-03-11 |
2024-03-14 |
Not clear |
| Amer Imraish, Tuqa Abu-Thiab, Hana Hamma. P Pharmacy practice. vol 21. issue 1. 2023-04-24. PMID:37090457. |
p p2 receptors have been implicated in the release of neurotransmitter and pro-inflammatory cytokines due to their response to neuro-excitatory substances in the microglia. |
2023-04-24 |
2023-08-14 |
Not clear |
| Possemato Elena, La Barbera Livia, Nobili Annalisa, Krashia Paraskevi, D'Amelio Marcell. The role of dopamine in NLRP3 inflammasome inhibition: implications for neurodegenerative diseases. Ageing research reviews. 2023-03-09. PMID:36893920. |
the neurotransmitter dopamine (da) is one of the players that negatively modulate nlrp3 inflammasome activation through da receptors expressed in both microglia and astrocytes. |
2023-03-09 |
2023-08-14 |
Not clear |
| Mengting Shang, Meng Tang, Yuying Xu. Neurodevelopmental toxicity induced by Airborne particulate matter. Journal of applied toxicology : JAT. 2022-08-22. PMID:35995895. |
in addition, human and animal exposure to pm can induce microglia activation, epigenetic alterations, alter the neurotransmitter levels, which may increase risks for development of ndd. |
2022-08-22 |
2023-08-14 |
human |
| Zhiqian Yu, Mai Sakai, Hotaka Fukushima, Chiaki Ono, Yoshie Kikuchi, Ryuta Koyama, Ko Matsui, Tomoyuki Furuyashiki, Satoshi Kida, Hiroaki Tomit. Contextual fear conditioning regulates synapse-related gene transcription in mouse microglia. Brain research bulletin. 2022-08-20. PMID:35987296. |
furthermore, in the hippocampal microglia, we found that the expression of neurotransmitter release regulators, γ-aminobutyric acid (gaba) receptor gabrb3 and synapsin 1/2, increased under fear memory consolidation and restored (decreased) after extinction. |
2022-08-20 |
2023-08-14 |
mouse |
| Lei Cao, Yanyan Kong, Bin Ji, Yutong Ren, Yihui Guan, Ruiqing N. Positron Emission Tomography in Animal Models of Tauopathies. Frontiers in aging neuroscience. vol 13. 2022-01-27. PMID:35082657. |
the advance in pet and imaging tracers have enabled non-invasive detection of the accumulation and spread of tau, the associated microglia activation, metabolic, and neurotransmitter receptor alterations in disease animal models. |
2022-01-27 |
2023-08-13 |
mouse |
| Susan L Anderse. Neuroinflammation, Early-Life Adversity, and Brain Development. Harvard review of psychiatry. vol 30. issue 1. 2022-01-07. PMID:34995033. |
microglia interactions with the inhibitory neurotransmitter gaba (specifically, the subtype expressing parvalbumin) are discussed within contexts of development and adversity. |
2022-01-07 |
2023-08-13 |
Not clear |
| Baiping Liu, Yongping Zhang, Zhiyou Yang, Meijun Liu, Cai Zhang, Yuntao Zhao, Cai Son. ω-3 DPA Protected Neurons from Neuroinflammation by Balancing Microglia M1/M2 Polarizations through Inhibiting NF-κB/MAPK p38 Signaling and Activating Neuron-BDNF-PI3K/AKT Pathways. Marine drugs. vol 19. issue 11. 2021-11-28. PMID:34822458. |
microglia m1 phenotype causes hpa axis hyperactivity, neurotransmitter dysfunction, and production of proinflammatory mediators and oxidants, which may contribute to the etiology of depression and neurodegenerative diseases. |
2021-11-28 |
2023-08-13 |
Not clear |
| Nofar Stolero, Dan Frenke. The dialog between neurons and microglia in Alzheimer's disease: The neurotransmitters view. Journal of neurochemistry. vol 158. issue 6. 2021-11-17. PMID:33314073. |
cross talk between specific neurons and microglia might occur through specific neurotransmitter receptors on microglia. |
2021-11-17 |
2023-08-13 |
Not clear |
| Yang Shi, Prabhakar Sairam Andhey, Christina Ising, Kairuo Wang, Lisa L Snipes, Kevin Boyer, Stephanie Lawson, Kaoru Yamada, Wei Qin, Melissa Manis, Javier Remolina Serrano, Bruno A Benitez, Robert E Schmidt, Maxim Artyomov, Jason D Ulrich, David M Holtzma. Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms. Neuron. vol 109. issue 15. 2021-08-13. PMID:34157306. |
apoe deficiency and ldlr ox strongly drive microglial immunometabolism toward enhanced catabolism over anabolism, whereas ldlr-overexpressing microglia also uniquely upregulate specific ion channels and neurotransmitter receptors upon activation. |
2021-08-13 |
2023-08-13 |
mouse |
| Andrei Turkin, Oksana Tuchina, Friederike Klempi. Microglia Function on Precursor Cells in the Adult Hippocampus and Their Responsiveness to Serotonin Signaling. Frontiers in cell and developmental biology. vol 9. 2021-06-12. PMID:34109176. |
recent evidence shows that microglia interact with serotonin, the neurotransmitter crucially involved in adult neurogenesis, and known for its role in antidepressant action. |
2021-06-12 |
2023-08-13 |
Not clear |
| Wei Zhang, Xiaojun Zhang, Yan Zhang, Chen Qu, Xiqiao Zhou, Shu Zhan. Histamine Induces Microglia Activation and the Release of Proinflammatory Mediators in Rat Brain Via H Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 15. issue 2. 2021-05-27. PMID:31863333. |
histamine induces microglia activation and the release of proinflammatory mediators in rat brain via h histamine is a major peripheral inflammatory mediator and a neurotransmitter in the central nervous system. |
2021-05-27 |
2023-08-13 |
rat |
| Liu L Yang, Vincent Millischer, Sergey Rodin, Derrick F MacFabe, Juan C Villaescusa, Catharina Lavebrat. Enteric short-chain fatty acids promote proliferation of human neural progenitor cells. Journal of neurochemistry. vol 154. issue 6. 2021-02-09. PMID:31784978. |
scfas play an important role in the 'gut-brain axis', regulating central nervous system processes, for example, cell-cell interaction, neurotransmitter synthesis and release, microglia activation, mitochondrial function, and gene expression. |
2021-02-09 |
2023-08-13 |
human |
| Huan Liu, Rehana K Leak, Xiaoming H. Neurotransmitter receptors on microglia. Stroke and vascular neurology. vol 1. issue 2. 2021-01-18. PMID:28959464. |
neurotransmitter receptors on microglia. |
2021-01-18 |
2023-08-13 |
Not clear |
| Huan Liu, Rehana K Leak, Xiaoming H. Neurotransmitter receptors on microglia. Stroke and vascular neurology. vol 1. issue 2. 2021-01-18. PMID:28959464. |
a variety of neurotransmitter receptors are expressed on microglia and help mediate the bidirectional communication between neurons and microglia. |
2021-01-18 |
2023-08-13 |
Not clear |
| Huan Liu, Rehana K Leak, Xiaoming H. Neurotransmitter receptors on microglia. Stroke and vascular neurology. vol 1. issue 2. 2021-01-18. PMID:28959464. |
here we review data supporting the importance of neurotransmitter receptors on microglia, with a special emphasis on glutamate, γ-aminobutyric acid (gaba), norepinephrine, cannabinoid and acetylcholine receptors. |
2021-01-18 |
2023-08-13 |
Not clear |
| Huan Liu, Rehana K Leak, Xiaoming H. Neurotransmitter receptors on microglia. Stroke and vascular neurology. vol 1. issue 2. 2021-01-18. PMID:28959464. |
elucidating the effects of neurotransmitter receptors on microglia and dissecting the underlying mechanisms may help accelerate the discovery of novel drugs that tap the therapeutic potential of microglia. |
2021-01-18 |
2023-08-13 |
Not clear |