All Relations between microglial cell and astrocyte

Publication Sentence Publish Date Extraction Date Species
Jinsong Xue, Keju Tao, Weijia Wang, Xiaofei Wan. What Can Inflammation Tell Us about Therapeutic Strategies for Parkinson's Disease? International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338925. additionally, we describe the potential anti-inflammatory therapies, including nod-like receptor pyrin domain containing protein 3 (nlrp3) inflammasome inhibition, nuclear factor κb (nf-κb) inhibition, microglia inhibition, astrocyte inhibition, nicotinamide adenine dinucleotide phosphate (nadph) oxidase inhibition, the peroxisome proliferator-activated receptor γ (pparγ) agonist, targeting the mitogen-activated protein kinase (mapk) pathway, targeting the adenosine monophosphate-activated protein kinase (ampk)-dependent pathway, targeting α-synuclein, targeting mirna, acupuncture, and exercise. 2024-02-10 2024-02-12 Not clear
Hiroko Ikeda, Aimi Yamagishi, Naomi Yonemochi, Shogo Yamamoto, Takatsune Shimizu, Akihiro Muto, John L Waddington, Junzo Kame. Keratinocyte-Derived Cytokine in the Hippocampus Disrupts Extinction of Conditioned Fear Memory in Tumor-Bearing Mice. Molecular neurobiology. 2024-02-03. PMID:38308664. the microglia inhibitor minocycline, but not the astrocyte inhibitor fluorocitrate, alleviated disruption in extinction of conditioned fear memory in tb mice. 2024-02-03 2024-02-06 mouse
Shiva Zeini, Nahid Davoodian, Seyed Abdollah Mousav. Gamma-oryzanol attenuates lipopolysaccharide-induced cognitive impairment by modulation of hippocampal inflammatory response and glial activation in mice. Journal of neuroimmunology. vol 387. 2024-01-26. PMID:38278081. also, neuronal loss, microglia, and astrocyte densities were evaluated in the ca1 and ca3 hippocampus. 2024-01-26 2024-01-29 mouse
Weizhuo Lu, Jiyue We. Crosstalk Among Glial Cells in the Blood-Brain Barrier Injury After Ischemic Stroke. Molecular neurobiology. 2024-01-26. PMID:38279077. specifically, we provided an updated overview of phenotypic transformation of microglia and astrocytes, as well as uncovered the crosstalk among astrocyte, microglia, and oligodendrocyte in the bbb disruption following ischemic stroke. 2024-01-26 2024-01-29 Not clear
Araks Martirosyan, Rizwan Ansari, Francisco Pestana, Katja Hebestreit, Hayk Gasparyan, Razmik Aleksanyan, Silvia Hnatova, Suresh Poovathingal, Catherine Marneffe, Dietmar R Thal, Andrew Kottick, Victor J Hanson-Smith, Sebastian Guelfi, William Plumbly, T Grant Belgard, Emmanouil Metzakopian, Matthew G Hol. Unravelling cell type-specific responses to Parkinson's Disease at single cell resolution. Molecular neurodegeneration. vol 19. issue 1. 2024-01-20. PMID:38245794. subpopulation analyses demonstrate a significant depletion of tyrosine hydroxylase (th) enriched astrocyte, microglia and oligodendrocyte populations in pd samples, as well as th enriched neurons, which are also depleted. 2024-01-20 2024-01-23 human
Max Gentenaar, Fleur L Meulmeester, Ximaine R van der Burg, Anna T Hoekstra, Hazel Hunt, Jan Kroon, Willeke M C van Roon-Mom, Onno C Meije. Glucocorticoid receptor antagonist CORT113176 attenuates motor and neuropathological symptoms of Huntington's disease in R6/2 mice. Experimental neurology. 2024-01-12. PMID:38216109. it also restored hd-related parameters including astrocyte markers in both the dorsolateral striatum and the hippocampus, and microglia markers in the hippocampus. 2024-01-12 2024-01-15 mouse
Tjokorda Istri Pramitasuri, Ni Made Susilawathi, Ni Made Adi Tarini, Aa Raka Sudewi, Matthew C Evan. Cholesterol dependent cytolysins and the brain: Revealing a potential therapeutic avenue for bacterial meningitis. AIMS microbiology. vol 9. issue 4. 2024-01-04. PMID:38173970. cdcs also observed to elicit intriguing effects on brain inflammation which involves microglia and astrocyte activations, along with neuronal damage as the end-point of pathological pathways in bacterial meningitis. 2024-01-04 2024-01-06 Not clear
Ming-Cong Li, Man-Zhong Li, Zi-Yue Lin, Yu-Ming Zhuang, Han-Yu Wang, Jing-Ting Jia, Yun Lu, Zhan-Jing Wang, Hai-Yan Zou, Hui Zha. Buyang Huanwu Decoction promotes neurovascular remodeling by modulating astrocyte and microglia polarization in ischemic stroke rats. Journal of ethnopharmacology. 2023-12-23. PMID:38141792. buyang huanwu decoction promotes neurovascular remodeling by modulating astrocyte and microglia polarization in ischemic stroke rats. 2023-12-23 2023-12-25 rat
Zeynep Kaya, Nevin Belder, Melike Sever-Bahcekapili, Buket Donmez-Demir, Şefik Evren Erdener, Naz Bozbeyoglu, Canan Bagci, Emine Eren-Kocak, Muge Yemisci, Hulya Karatas, Esra Erdemli, Ihsan Gursel, Turgay Dalkar. Vesicular HMGB1 release from neurons stressed with spreading depolarization enables confined inflammatory signaling to astrocytes. Journal of neuroinflammation. vol 20. issue 1. 2023-12-12. PMID:38082296. ezcolocalization and costes thresholding algorithms were used to assess the colocalization of small extracellular vesicles (sevs) carrying hmgb1 with astrocyte or microglia processes. 2023-12-12 2023-12-17 mouse
Hongyoon Choi, Eun Ji Lee, Jin Seop Shin, Hyun Kim, Sungwoo Bae, Yoori Choi, Dong Soo Le. Spatiotemporal characterization of glial cell activation in an Alzheimer's disease model by spatially resolved transcriptomics. Experimental & molecular medicine. 2023-11-30. PMID:38036733. we confirmed that disease-associated microglia (dam) and astrocyte (daa) signatures also showed initial changes in wm and that activation spreads to gm. 2023-11-30 2023-12-10 mouse
Weizhuo Lu, Zhiwu Chen, Jiyue We. Flavonoids and ischemic stroke-induced neuroinflammation: Focus on the glial cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 170. 2023-11-28. PMID:38016362. in this review, we focused on the dual roles of activated microglia and reactive astrocyte in the neuroinflammation following ischemic stroke and discussed the anti-neuroinflammation of some flavonoids. 2023-11-28 2023-12-07 Not clear
Zhen Mei, Jiaqi Liu, Jason P Schroeder, David Weinshenker, Duc M Duong, Nicholas T Seyfried, Yujing Li, Peng Jin, Aliza P Wingo, Thomas S Wing. Lowering Hippocampal miR-29a Expression Slows Cognitive Decline and Reduces Beta-Amyloid Deposition in 5×FAD Mice. Molecular neurobiology. 2023-11-22. PMID:37989983. mir-29a sponge significantly reduced hippocampal beta-amyloid deposition in 5×fad mice and lowered astrocyte and microglia activation in both 5×fad and wt mice. 2023-11-22 2023-11-29 mouse
Kozo Saito, Eiji Shigetomi, Youichi Shinozaki, Kenji Kobayashi, Bijay Parajuli, Yuto Kubota, Kent Sakai, Miho Miyakawa, Hiroshi Horiuchi, Junichi Nabekura, Schuichi Koizum. Microglia sense astrocyte dysfunction and prevent disease progression in an Alexander disease model. Brain : a journal of neurology. 2023-11-13. PMID:37955589. microglia sense astrocyte dysfunction and prevent disease progression in an alexander disease model. 2023-11-13 2023-11-20 mouse
b' Mengqin Zhou, Peng Su, Jingyan Liang, \\xe5\\xa4\\xa9 \\xe5\\xba\\x86 \\xe7\\x86\\x8. Research progress on the roles of neurovascular unit in stroke-induced immunosuppression. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. vol 52. issue 5. 2023-10-30. PMID:37899404.' the neurovascular unit (nvu) is a complex multi-cellular structure consisting of neurons, endothelial cells, pericyte, astrocyte, microglia and extracellular matrix, etc. 2023-10-30 2023-11-08 Not clear
Jonathan C Vincent, Colleen N Garnett, James B Watson, Emma K Higgins, Teresa Macheda, Lydia Sanders, Kelly N Roberts, Ryan K Shahidehpour, Eric M Blalock, Ning Qaun, Adam D Bachstette. IL-1R1 signaling in TBI: assessing chronic impacts and neuroinflammatory dynamics in a mouse model of mild closed-head injury. Journal of neuroinflammation. vol 20. issue 1. 2023-10-26. PMID:37884959. we found that il-1r1 gko attenuated behavioral impairments 14 weeks post-injury and reduced reactive microglia and astrocyte staining in the neocortex, corpus callosum, and hippocampus. 2023-10-26 2023-11-08 mouse
Chiara Orciani, Sonia Do Carmo, Morgan K Foret, Helene Hall, Quentin Bonomo, Agustina Lavagna, Chunwei Huang, A Claudio Cuell. Early treatment with an M1 and sigma-1 receptor agonist prevents cognitive decline in a transgenic rat model displaying Alzheimer-like amyloid pathology. Neurobiology of aging. vol 132. 2023-10-21. PMID:37864952. af710b treatment also reduced microglia and astrocyte recruitment toward ca1 hippocampal aβ-burdened neurons compared to vehicle-treated mcgill-r-thy1-app rats, also altering the inflammatory cytokines profile. 2023-10-21 2023-11-08 rat
Jee Youn Lee, Chan Sol Park, Kyung Jin Seo, In Yi Kim, Sungmin Han, Inchan Youn, Tae Young Yun. IL-6/JAK2/STAT3 axis mediates neuropathic pain by regulating astrocyte and microglia activation after spinal cord injury. Experimental neurology. 2023-10-20. PMID:37863306. one month after contusive sci, the activation of jak2/stat3 pathway was markedly upregulated in both microglia and astrocyte in nociceptive processing regions of the lumbar spinal cord. 2023-10-20 2023-11-08 rat
Jee Youn Lee, Chan Sol Park, Kyung Jin Seo, In Yi Kim, Sungmin Han, Inchan Youn, Tae Young Yun. IL-6/JAK2/STAT3 axis mediates neuropathic pain by regulating astrocyte and microglia activation after spinal cord injury. Experimental neurology. 2023-10-20. PMID:37863306. il-6/jak2/stat3 axis mediates neuropathic pain by regulating astrocyte and microglia activation after spinal cord injury. 2023-10-20 2023-11-08 rat
Jee Youn Lee, Chan Sol Park, Kyung Jin Seo, In Yi Kim, Sungmin Han, Inchan Youn, Tae Young Yun. IL-6/JAK2/STAT3 axis mediates neuropathic pain by regulating astrocyte and microglia activation after spinal cord injury. Experimental neurology. 2023-10-20. PMID:37863306. in particular, ag490 treatment inhibited both microglial and astrocyte activation in the lumbar (l) 4-5 dorsal horn and significantly decreased levels of p-p38mapk, p-erk and p-jnk, which are known to be activated in microglia (p-p38mapk and p-erk) and astrocyte (p-jnk). 2023-10-20 2023-11-08 rat
Jacqueline Barker, Lauren Buck, Qiaowei Xie, Michelle Willis, Christine Side, Laura Giacometti, Peter Gaskill, Kyewon Park, Farida Shaheen, Lili Guo, Santhi Gorantl. Impaired extinction of cocaine seeking in HIV-infected mice is accompanied by peripheral and central immune dysregulation. Research square. 2023-10-16. PMID:37841842. behavioral alterations were accompanied by immune changes in hiv infected mice, including increased prefrontal cortex astrocyte immunoreactivity and brain-region specific effects on microglia number and reactivity. 2023-10-16 2023-11-08 mouse