| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexandra J Trevisan, Katie Han, Phillip Chapman, Anand S Kulkarni, Jennifer M Hinton, Cody Ramirez, Ines Klein, Graziana Gatto, Mariano I Gabitto, Vilas Menon, Jay B Bikof. The transcriptomic landscape of spinal V1 interneurons reveals a role for En1 in specific elements of motor output. bioRxiv : the preprint server for biology. 2024-09-30. PMID:39345580. |
despite progress in revealing the cellular architecture of the spinal cord, the extent of cell type heterogeneity within interneuron populations remains unclear. |
2024-09-30 |
2024-10-02 |
Not clear |
| Yajie Hu, Fengxian Cui, Shenglan Wang, Chen Liu, Shengxiong Zhang, Ruiqi Wang, Jie Song, Yunhui Zhan. MicroRNA expression profile of human umbilical vein endothelial cells in response to coxsackievirus A10 infection reveals a potential role of miR-143-3p in maintaining the integrity of the blood-brain barrier. Frontiers in cellular and infection microbiology. vol 13. 2023-08-14. PMID:37577373. |
after that, gene target prediction and functional annotation revealed that the targets of these dysregulated mirnas were mostly enriched in cell proliferation, signal transduction, camp signalling pathway, cellular response to interleukin-6, ventral spinal cord interneuron differentiation, negative regulation of glial cell differentiation, neuron migration, positive regulation of neuron projection development, etc., which were primarily involved in the processes of basic physiology, host immunity, and neurological impairments and further reflected vital regulatory roles of mirna in viral pathogenicity. |
2023-08-14 |
2023-08-16 |
human |
| John R Walker, Megan Ryan Detlof. Plasticity in Cervical Motor Circuits following Spinal Cord Injury and Rehabilitation. Biology. vol 10. issue 10. 2021-11-03. PMID:34681075. |
however, this review focuses on the influence of physical therapy and primary afferent input and interneuron modulation in driving plasticity within the spinal cord. |
2021-11-03 |
2023-08-13 |
Not clear |
| José Luis Juárez-Morales, Frida Weierud, Samantha J England, Celia Demby, Nicole Santos, Ginny Grieb, Sylvie Mazan, Katharine E Lewi. Evolution of lbx spinal cord expression and function. Evolution & development. vol 23. issue 5. 2021-10-30. PMID:34411410. |
our data examining lbx expression in scyliorhinus canicula and xenopus tropicalis suggest that the spinal interneuron expression of zebrafish lbx1a is ancestral, whereas lbx1b has acquired a new expression pattern in spinal cord progenitor cells. |
2021-10-30 |
2023-08-13 |
mouse |
| Dylan Deska-Gauthier, Ying Zhan. The Temporal Mechanisms Guiding Interneuron Differentiation in the Spinal Cord. International journal of molecular sciences. vol 22. issue 15. 2021-09-08. PMID:34360788. |
the temporal mechanisms guiding interneuron differentiation in the spinal cord. |
2021-09-08 |
2023-08-13 |
mouse |
| Dylan Deska-Gauthier, Ying Zhan. The Temporal Mechanisms Guiding Interneuron Differentiation in the Spinal Cord. International journal of molecular sciences. vol 22. issue 15. 2021-09-08. PMID:34360788. |
in the mouse spinal cord, growing evidence is beginning to reveal that neurogenesis timing acts in tandem with spatial molecular controls to diversify molecularly and functionally distinct post-mitotic interneuron subpopulations. |
2021-09-08 |
2023-08-13 |
mouse |
| Vladimir Rancic, Simon Gosgnac. Recent Insights into the Rhythmogenic Core of the Locomotor CPG. International journal of molecular sciences. vol 22. issue 3. 2021-09-07. PMID:33573259. |
for more than a century, it has been known that the timing and pattern of stepping movements in mammals are generated by neural networks known as central pattern generators (cpgs), which comprise multiple interneuron cell types located entirely within the spinal cord. |
2021-09-07 |
2023-08-13 |
Not clear |
| Stéphane Nedelec, Alfonso Martinez-Aria. In vitro models of spinal motor circuit's development in mammals: achievements and challenges. Current opinion in neurobiology. vol 66. 2021-05-25. PMID:33677159. |
the connectivity patterns of neurons sustaining the functionality of spinal locomotor circuits rely on the specification of hundreds of motor neuron and interneuron subtypes precisely arrayed within the embryonic spinal cord. |
2021-05-25 |
2023-08-13 |
mouse |
| Lyandysha V Zholudeva, Victoria E Abraira, Kajana Satkunendrarajah, Todd C McDevitt, Martyn D Goulding, David S K Magnuson, Michael A Lan. Spinal Interneurons as Gatekeepers to Neuroplasticity after Injury or Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 5. 2021-04-28. PMID:33472820. |
this review highlights our current understanding of spinal interneuron heterogeneity, their contribution to control and modulation of motor and sensory functions, and how this role might change after traumatic spinal cord injury. |
2021-04-28 |
2023-08-13 |
Not clear |
| Takamasa Mizoguchi, Michi Fukada, Miku Iihama, Xuehui Song, Shun Fukagawa, Shuhei Kuwabara, Shuhei Omaru, Shin-Ichi Higashijima, Motoyuki Ito. Transient activation of the Notch-her15.1 axis plays an important role in the maturation of V2b interneurons. Development (Cambridge, England). vol 147. issue 16. 2021-03-23. PMID:32855202. |
in the vertebrate ventral spinal cord, p2 progenitors give rise to two interneuron subtypes: excitatory v2a interneurons and inhibitory v2b interneurons. |
2021-03-23 |
2023-08-13 |
zebrafish |
| Karolina U Kabayiza, Gauhar Masgutova, Audrey Harris, Vincent Rucchin, Benvenuto Jacob, Frédéric Clotma. The Onecut Transcription Factors Regulate Differentiation and Distribution of Dorsal Interneurons during Spinal Cord Development. Frontiers in molecular neuroscience. vol 10. 2020-10-01. PMID:28603487. |
during embryonic development, the dorsal spinal cord generates numerous interneuron populations eventually involved in motor circuits or in sensory networks that integrate and transmit sensory inputs from the periphery. |
2020-10-01 |
2023-08-13 |
Not clear |
| Michael G Z Ghal. Microsurgical technique for concurrent cervical corpectomy and ventral phrenic nerve access in the rat. MethodsX. vol 6. 2020-09-29. PMID:30766804. |
ventral spinal cord access, however, facilitates neuronal (e.g., phrenic motoneuron and interneuron) recordings in the ventral horn of the spinal cord, given greater proximity to the ventral compared to the dorsal surface of the spinal cord providing more leeway in recording pipette insertion point and trajectory. |
2020-09-29 |
2023-08-13 |
rat |
| Søren S L Anderse. Real time large scale in vivo observations reveal intrinsic synchrony, plasticity and growth cone dynamics of midline crossing axons at the ventral floor plate of the zebrafish spinal cord. Journal of integrative neuroscience. vol 18. issue 4. 2020-06-22. PMID:31912693. |
here then, applying light-sheet microscopy, axonal growth and guidance at the floor plate are followed in vivo in real time at high resolution along several hundred micrometers of the zebrafish spinal cord by using an interneuron expressing gfp as a model axon. |
2020-06-22 |
2023-08-13 |
zebrafish |
| K A Streeter, M D Sunshine, S R Patel, E J Gonzalez-Rothi, P J Reier, D M Baekey, D D Fulle. Mid-cervical interneuron networks following high cervical spinal cord injury. Respiratory physiology & neurobiology. vol 271. 2020-06-05. PMID:31553921. |
mid-cervical interneuron networks following high cervical spinal cord injury. |
2020-06-05 |
2023-08-13 |
rat |
| Sharn Perry, Martin Larhammar, Jennifer Vieillard, Chetan Nagaraja, Markus M Hilscher, Atieh Tafreshiha, Fadi Rofo, Fabio V Caixeta, Klas Kullande. Characterization of Dmrt3-Derived Neurons Suggest a Role within Locomotor Circuits. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 10. 2020-03-23. PMID:30578339. |
the transcription factor doublesex and mab-3-related transcription factor 3 (dmrt3) is involved in the differentiation of the dorsal interneuron 6 class of spinal cord interneurons. |
2020-03-23 |
2023-08-13 |
Not clear |
| Vanessa Gerber, Lixin Yang, Masanari Takamiya, Vanessa Ribes, Victor Gourain, Ravindra Peravali, Johannes Stegmaier, Ralf Mikut, Markus Reischl, Marco Ferg, Sepand Rastegar, Uwe Strähl. The HMG box transcription factors Sox1a and Sox1b specify a new class of glycinergic interneuron in the spinal cord of zebrafish embryos. Development (Cambridge, England). vol 146. issue 4. 2020-01-02. PMID:30760481. |
the hmg box transcription factors sox1a and sox1b specify a new class of glycinergic interneuron in the spinal cord of zebrafish embryos. |
2020-01-02 |
2023-08-13 |
zebrafish |
| Stefane A Aguiar, Supriyo Choudhury, Hrishikesh Kumar, Monica A Perez, Stuart N Bake. Effect of central lesions on a spinal circuit facilitating human wrist flexors. Scientific reports. vol 8. issue 1. 2019-11-25. PMID:30287827. |
spinal cord injury results possibly reflect damage to the segmental interneuron pathways. |
2019-11-25 |
2023-08-13 |
human |
| Si Chen, Guangqi Yang, Yaxi Zhu, Zongwei Liu, Weiping Wang, Jiayou Wei, Keyi Li, Jiajia Wu, Zhi Chen, Youlan Li, Shuhua Mu, Lisi OuYang, Wanlong Le. A Comparative Study of Three Interneuron Types in the Rat Spinal Cord. PloS one. vol 11. issue 9. 2019-11-20. PMID:27658248. |
a comparative study of three interneuron types in the rat spinal cord. |
2019-11-20 |
2023-08-13 |
rat |
| Francisco J Alvare. Spinal Interneurons "à La Carte". Neuron. vol 100. issue 1. 2019-07-31. PMID:30308170. |
the study of interneuron diversity in the spinal cord is complex and needs new models that can accelerate discovery. |
2019-07-31 |
2023-08-13 |
Not clear |
| Marito Hayashi, Christopher A Hinckley, Shawn P Driscoll, Niall J Moore, Ariel J Levine, Kathryn L Hilde, Kamal Sharma, Samuel L Pfaf. Graded Arrays of Spinal and Supraspinal V2a Interneuron Subtypes Underlie Forelimb and Hindlimb Motor Control. Neuron. vol 97. issue 4. 2019-07-15. PMID:29398364. |
nevertheless, it remains unclear how segment-specific motor computations are processed because the cardinal interneuron classes that control motor neurons appear uniform at each level of the spinal cord. |
2019-07-15 |
2023-08-13 |
Not clear |