| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael B Ryan, Allison E Girasole, Andrew J Flores, Emily L Twedell, Matthew M McGregor, Rea Brakaj, Ronald F Paletzki, Thomas S Hnasko, Charles R Gerfen, Alexandra B Nelso. Excessive firing of dyskinesia-associated striatal direct pathway neurons is gated by dopamine and excitatory synaptic input. Cell reports. vol 43. issue 8. 2024-07-18. PMID:39024096. |
the striatum integrates dopaminergic and glutamatergic inputs to select preferred versus alternative actions. |
2024-07-18 |
2024-07-21 |
mouse |
| Parya Alizadeh Khosroshahi, Mohammad Ghanbar. MicroRNA dysregulation in glutamate and dopamine pathways of schizophrenia: From molecular pathways to diagnostic and therapeutic approaches. Progress in neuro-psychopharmacology & biological psychiatry. 2024-07-13. PMID:39002925. |
dysregulated glutamatergic and dopaminergic transmission pathways are involved in schizophrenia development. |
2024-07-13 |
2024-07-16 |
Not clear |
| Parya Alizadeh Khosroshahi, Mohammad Ghanbar. MicroRNA dysregulation in glutamate and dopamine pathways of schizophrenia: From molecular pathways to diagnostic and therapeutic approaches. Progress in neuro-psychopharmacology & biological psychiatry. 2024-07-13. PMID:39002925. |
in this study, we reviewed the glutamatergic and dopaminergic pathophysiology and highlighted the role of mirna dysregulation in schizophrenia development. |
2024-07-13 |
2024-07-16 |
Not clear |
| Heather C Aziz, Regina A Mangier. Sex differences in membrane properties and cellular excitability of dopamine D1 receptor-expressing neurons within the shell of the nucleus accumbens of pre- and mid-adolescent mice. Biology of sex differences. vol 15. issue 1. 2024-07-13. PMID:39003495. |
changes in dopaminergic and glutamatergic systems occur during adolescence and converge in the nac. |
2024-07-13 |
2024-07-16 |
mouse |
| Hiroyuki Ichijo, Nguyen Thi Van Trang, Tomoya Nakamur. Topographic Organization of Glutamatergic and GABAergic Parvalbumin Positive Neurons in the Lateral Habenula. eNeuro. 2024-07-03. PMID:38960707. |
to achieve this, we investigated the proportions of the transmitter machinery in lhb pv neurons, including gabaergic, glutamatergic, serotonergic, cholinergic, and dopaminergic neurotransmitter markers, using transcriptome analysis, mrna in situ hybridization chain reaction, and immunohistochemistry. |
2024-07-03 |
2024-07-10 |
mouse |
| Antonio Del Casale, Martina Nicole Modesti, Giovanna Gentile, Cecilia Guariglia, Stefano Ferracuti, Maurizio Simmaco, Marina Borr. Is the Hedgehog Pathway Involved in the Pathophysiology of Schizophrenia? A Systematic Review of Current Evidence of Neural Molecular Correlates and Perspectives on Drug Development. Current issues in molecular biology. vol 46. issue 6. 2024-06-26. PMID:38920990. |
the hh pathway is crucial in the development of midbrain dopaminergic neurons, neuroplasticity mechanisms, regulating astrocyte phenotype and function, brain-derived neurotrophic factor expression, brain glutamatergic neural transmission, and responses to antipsychotics. |
2024-06-26 |
2024-06-29 |
human |
| Ari Brouwer, Robin L Carhart-Harris, Charles L Raiso. Psychotomimetic compensation versus sensitization. Pharmacology research & perspectives. vol 12. issue 4. 2024-06-26. PMID:38923845. |
psychotomimetic compensation refers to a short-term stressor or drug-induced compensation against stress that is facilitated by engagement of neurotransmitter/modulator systems (endocannabinoid, serotonergic, glutamatergic and dopaminergic) that mediate the effects of common psychotomimetic drugs. |
2024-06-26 |
2024-06-29 |
Not clear |
| Jamie C Moffa, India N Bland, Jessica R Tooley, Vani Kalyanaraman, Monique Heitmeier, Meaghan C Creed, Bryan A Copit. Cell specific single viral vector CRISPR/Cas9 editing and genetically encoded tool delivery in the central and peripheral nervous systems. eNeuro. 2024-06-13. PMID:38871457. |
we tested these tools in multiple brain regions and cell types, including gabaergic neurons in the nucleus accumbens, glutamatergic neurons projecting from the ventral pallidum to the lateral habenula, dopaminergic neurons in the ventral tegmental area, and proprioceptive neurons in the periphery. |
2024-06-13 |
2024-06-16 |
mouse |
| Tannaz Safari, Mahdi Dehbozorgi, Bordes Lauren. Pseudobulbar Affect in an Elderly Female With Small Vessel Ischemic Disease and Alcohol Abuse Disorder: A Case Report. Cureus. vol 16. issue 5. 2024-05-21. PMID:38764710. |
the precise underlying cause of pba remains unknown; however, existing evidence suggests the involvement of dopaminergic, serotonergic, and glutamatergic neurotransmission within the corticopontine-cerebellar pathways responsible for regulating the motor expression of emotions. |
2024-05-21 |
2024-05-27 |
Not clear |
| Halina Falfushynska, Piotr Rychter, Anastasiia Boshtova, Yuliia Faidiuk, Nadiia Kasianchuk, Piotr Rzymsk. Illicit Drugs in Surface Waters: How to Get Fish off the Addictive Hook. Pharmaceuticals (Basel, Switzerland). vol 17. issue 4. 2024-04-27. PMID:38675497. |
exposure to such xenobiotics can induce oxidative stress and dysfunction to mitochondrial and lysosomal function, distort locomotion activity by regulating the dopaminergic and glutamatergic systems, increase the predation risk, instigate neurological disorders, disbalance neurotransmission, and produce histopathological alterations in the brain and liver tissues, similar to those described in mammals. |
2024-04-27 |
2024-04-29 |
human |
| Quyen B Do, Humaira Noor, Ricardo Marquez-Gomez, Kaitlyn M L Cramb, Bryan Ng, Ajantha Abbey, Naroa Ibarra-Aizpurua, Maria Claudia Caiazza, Parnaz Sharifi, Charmaine Lang, Dayne Beccano-Kelly, Jimena Baleriola, Nora Bengoa-Vergniory, Richard Wade-Martin. Early deficits in an in vitro striatal microcircuit model carrying the Parkinson's GBA-N370S mutation. NPJ Parkinson's disease. vol 10. issue 1. 2024-04-12. PMID:38609392. |
we found that, cortical glutamatergic projections facilitated msn synaptic activity, and dopaminergic transmission enhanced maturation of msns in vitro. |
2024-04-12 |
2024-04-15 |
Not clear |
| Peyton Christine Bendis, Sydney Zimmerman, Anna Onisiforou, Panos Zanos, Polymnia Georgio. The impact of estradiol on serotonin, glutamate, and dopamine systems. Frontiers in neuroscience. vol 18. 2024-04-08. PMID:38586193. |
these neurotransmitter systems encompass the serotonergic, dopaminergic, and glutamatergic signaling pathways. |
2024-04-08 |
2024-04-10 |
human |
| Boxuan Li, Shizhe Deng, Hailun Jiang, Weiming Zhu, Bifang Zhuo, Yuzheng Du, Zhihong Men. The mechanistic effects of acupuncture in rodent neurodegenerative disease models: a literature review. Frontiers in neuroscience. vol 18. 2024-03-19. PMID:38500484. |
here, we reviewed the therapeutic mechanisms of acupuncture at the neural circuit level in movement and cognition disorders, summarizing the influence of acupuncture in the dopaminergic system, glutamatergic system, γ-amino butyric acid-ergic (gabaergic) system, serotonergic system, cholinergic system, and glial cells at the circuit and synaptic levels. |
2024-03-19 |
2024-03-21 |
Not clear |
| Huanliang Liu, Xiaochao Tan, Yu Wu, Xiaona Li, Zhiyong Hu, Shuhan Lei, Wendong Fan, Zhenyu Wan. Long-term exposure to 6-PPD quinone at environmentally relevant concentrations causes neurotoxicity by affecting dopaminergic, serotonergic, glutamatergic, and GABAergic neuronal systems in Caenorhabditis elegans. The Science of the total environment. 2024-02-29. PMID:38423311. |
lastly, pearson's correlation analysis showed that locomotion behavior and sensory perception behavior were positively correlated with the dopaminergic, serotonergic, glutamatergic, and gabaergic neurotransmission. |
2024-02-29 |
2024-03-03 |
caenorhabditis_elegans |
| Fabrizio Turiaco, Chiara Cullotta, Federica Mannino, Antonio Bruno, Francesco Squadrito, Giovanni Pallio, Natasha Irrer. Attention Deficit Hyperactivity Disorder (ADHD) and Polyphenols: A Systematic Review. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338814. |
thus, a neuroinflammatory state may influence the neurotransmitters pathways, such as the noradrenergic, glutamatergic, serotoninergic, and, in particular, dopaminergic ones, whose impairment is strongly associated with attention deficit hyperactivity disorder (adhd). |
2024-02-10 |
2024-02-12 |
Not clear |
| Tomás Mouro Ferraz Lima, João Mauricio Castaldelli-Maia, Gisèle Apter, Kae Leopold. Neurobiological associations between smoking and internalizing disorders. International review of psychiatry (Abingdon, England). vol 35. issue 5-6. 2024-02-01. PMID:38299645. |
nicotine improves dopaminergic signalling and balances glutamatergic and gabaergic pathways, improving symptoms and increasing the risk of nicotine dependence. |
2024-02-01 |
2024-02-03 |
Not clear |
| Petra Mocellin, Oliver Barnstedt, Kevin Luxem, Hiroshi Kaneko, Silvia Vieweg, Julia U Henschke, Dennis Dalügge, Falko Fuhrmann, Anna Karpova, Janelle M P Pakan, Michael R Kreutz, Sanja Mikulovic, Stefan Rem. A septal-ventral tegmental area circuit drives exploratory behavior. Neuron. 2024-01-24. PMID:38266645. |
mechanistically, this role relies on glutamatergic msdb projections that monosynaptically target a subset of both glutamatergic and dopaminergic vta neurons. |
2024-01-24 |
2024-01-27 |
mouse |
| Adam Wojtas, Krystyna Gołembiowsk. Molecular and Medical Aspects of Psychedelics. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203411. |
the data show a significant effect of nbomes on glutamatergic, dopaminergic, serotonergic, and cholinergic neurotransmission in the frontal cortex, striatum, and nucleus accumbens. |
2024-01-11 |
2024-01-13 |
rat |
| Milan D Valyear, Alexa Brown, Ghislaine Deyab, Franz R Villaruel, Soraya Lahlou, Nina Caporicci-Dinucci, Nadia Chaudhr. Augmenting glutamatergic, but not dopaminergic, activity in the nucleus accumbens shell disrupts responding to a discrete alcohol cue in an alcohol context. The European journal of neuroscience. 2024-01-08. PMID:38185906. |
augmenting glutamatergic, but not dopaminergic, activity in the nucleus accumbens shell disrupts responding to a discrete alcohol cue in an alcohol context. |
2024-01-08 |
2024-01-10 |
rat |
| Sung M Yang, Ayan Ghoshal, Jeffrey M Hubbard, Florian Gackière, Romain Teyssié, Stuart A Neale, Seth C Hopkins, Kenneth S Koblan, Linda J Bristow, Nina Dedi. TAAR1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-12-19. PMID:38110609. |
aberrant dopaminergic and glutamatergic function, particularly within the striatum and hippocampus, has repeatedly been associated with the pathophysiology of schizophrenia. |
2023-12-19 |
2023-12-21 |
mouse |