| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenhui Lu, Ting Zhang, Minghui Li, Jun Zhang, Ningning Liu, Lanfang Yang, Guomin Huan. Clinical efficacy and potential mechanisms of acupuncture for Parkinson's disease: the role of GABAergic signaling. Frontiers in neuroscience. vol 19. 2025-03-06. PMID:40046435. |
gaba is an important inhibitory neurotransmitter in the central nervous system (cns), synthesized through the alpha decarboxylation reaction of glutamate (glu) under the action of glutamic acid decarboxylase (gad) in gabaergic neurons. |
2025-03-06 |
2025-03-08 |
Not clear |
| Nian Liu, Jiacheng He, Yanmei Yang, Yunlong Wang, Lingwei Zhang, Ziqi Xiao, Zhen Xiong, Shangxun Zhong, Yuwei Xu, Yang Gu, Jianyi Wang, Yufei Lan, Ying Du, Pingping Zhu, Zhi Zhang, Xinjuan Fan, Benyu Liu, Zusen Fa. Enteric GABAergic neuron-derived γ-aminobutyric acid initiates expression of Igfbp7 to sustain ILC3 homeostasis. Nature immunology. vol 26. issue 3. 2025-03-03. PMID:40033120. |
here, we identified that the enteric gabaergic neuron-derived neurotransmitter γ-aminobutyric acid (gaba) inhibited proliferation and il-17a production in ilc3s in a manner dependent on the gaba receptors gabbr1 and gabbr2. |
2025-03-03 |
2025-03-06 |
Not clear |
| Junia Lara de Deus, Juliana Marino Maia, Renato Nery Soriano, Mateus R Amorim, Luiz G S Branc. Psychedelics in neuroinflammation: Mechanisms and therapeutic potential. Progress in neuro-psychopharmacology & biological psychiatry. 2025-02-01. PMID:39892847. |
beyond the serotonergic system, other neurotransmitter systems-including the glutamatergic, dopaminergic, noradrenergic, gamma-aminobutyric acid (gabaergic), and cholinergic systems-also play significant roles in mediating the effects of psychedelics. |
2025-02-01 |
2025-02-04 |
Not clear |
| Sami Awda Algaid. Chronic stress-induced neuroplasticity in the prefrontal cortex: Structural, functional, and molecular mechanisms from development to aging. Brain research. 2025-01-26. PMID:39864644. |
these structural changes are accompanied by disruptions in neurotransmitter systems, most notably glutamatergic and gabaergic signaling, and alterations in synaptic plasticity mechanisms. |
2025-01-26 |
2025-01-29 |
Not clear |
| Maximiliano Abarca, Humberto Pizarro, M Leonor Bustamante, Gustav Rohde, Marcelo Arancibi. Genetic and neurobiological aspects of psychosis in major neurocognitive disorder. Medwave. vol 25. issue 1. 2025-01-08. PMID:39772397. |
on the other hand, alterations of the cholinergic, serotonergic, dopaminergic, and gabaergic neurotransmitter systems and the excitatory-inhibitory balance have been described in dementia. |
2025-01-08 |
2025-01-13 |
Not clear |
| Mayur B Kale, Nitu L Wankhede, Barkha K Goyanka, Reena Gupta, Ashok Kumar Bishoyi, Deepak Nathiya, Parjinder Kaur, Kumari Shanno, Brijesh G Taksande, Mohammad Khalid, Aman B Upaganlawar, Milind J Umekar, Monica Gulati, Monika Sachdeva, Tapan Behl, Amin Gasm. Unveiling the Neurotransmitter Symphony: Dynamic Shifts in Neurotransmitter Levels during Menstruation. Reproductive sciences (Thousand Oaks, Calif.). 2024-11-19. PMID:39562466. |
menstruation is characterized by declining estrogen and progesterone, potentially leading to mood disturbances, fluctuating gabaergic and dopaminergic neurotransmitter systems, relaxation, fatigue, motivation, and pleasure variations. |
2024-11-19 |
2024-11-23 |
Not clear |
| Martina Cuccarelli, Alessandro Zampogna, Antonio Supp. The broad spectrum of malignant syndromes. Neurobiology of disease. 2024-11-14. PMID:39542220. |
while distinct mechanisms may initially trigger the different malignant syndromes, a final common pathway leading to similar signs and symptoms involves various neurotransmitter systems, including dopaminergic, serotonergic, gabaergic, glycinergic, and glutamatergic pathways. |
2024-11-14 |
2024-11-17 |
Not clear |
| Pascal Grumbach, Jan Kasper, Joerg F Hipp, Anna Forsyth, Sofie L Valk, Suresh Muthukumaraswamy, Simon B Eickhoff, Leonhard Schilbach, Juergen Dukar. Local activity alterations in autism spectrum disorder correlate with neurotransmitter properties and ketamine induced brain changes. medRxiv : the preprint server for health sciences. 2024-11-06. PMID:39502665. |
we then tested how these lcor alterations co-localize with specific neurotransmitter systems derived from nuclear imaging and compared them with e/i changes induced by gabaergic (midazolam) and glutamatergic medication (ketamine). |
2024-11-06 |
2024-11-08 |
human |
| Pajaree Sonsungsan, Supatha Aimauthon, Nattawet Sriwichai, Poommaree Namchai. Unveiling mitochondria as central components driving cognitive decline in alzheimer's disease through cross-transcriptomic analysis of hippocampus and entorhinal cortex microarray datasets. Heliyon. vol 10. issue 20. 2024-11-05. PMID:39498000. |
the enrichment analysis in ca1 of hc revealed differentiation in gene expression related to mitochondrial membrane functions involved in bioenergetics, mitochondrial electron transport, and biological processes associated with microtubule-based process, while analysis in the ec region showed enrichment in synaptic vesicle dynamics which is associated with neurotransmitter release and the regulation of postsynaptic membrane potential and synaptic transmission of gabaergic and glutamatergic synapse. |
2024-11-05 |
2024-11-07 |
Not clear |
| Gianna Spitta, Tobias Gleich, Lea Mascarell Maricic, Annika Rosenthal, Florian Schubert, Semiha Aydin, Andreas Heinz, Jürgen Gallina. Reduced GABA Levels in the ACC of Actively Drinking High Risk Individuals Compared to Recently Detoxified Alcohol-Dependent Patients. Journal of integrative neuroscience. vol 23. issue 10. 2024-10-30. PMID:39473159. |
acute gamma-aminobutyric acid (gabaergic) effects of alcohol consumption are well-known, whereas prior research has yielded inconsistent findings regarding on adaptations of the gabaergic neurotransmitter system to chronic alcohol use. |
2024-10-30 |
2024-11-02 |
Not clear |
| Yang Liu, Yongkai Chen, Carly R Duffy, Ariel J VanLeuven, John Branson Byers, Hannah C Schriever, Rebecca E Ball, Jessica M Carpenter, Chelsea E Gunderson, Nikolay M Filipov, Ping Ma, Peter A Kner, James D Lauderdal. Decreased GABA levels during development result in increased connectivity in the larval zebrafish tectum. bioRxiv : the preprint server for biology. 2024-09-24. PMID:39314470. |
later in cns development, gabaergic signaling acts in an inhibitory manner when it becomes the predominant inhibitory neurotransmitter in the brain. |
2024-09-24 |
2024-09-26 |
human |
| Megan E Barra, Ken Solt, Xin Yu, Brian L Edlo. Restoring consciousness with pharmacologic therapy: Mechanisms, targets, and future directions. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2024-07-17. PMID:39019729. |
however, the relative contributions of monoaminergic, glutamatergic, cholinergic, gabaergic, and orexinergic neurotransmitter systems to recovery of consciousness after severe brain injury are unknown, and personalized approaches to targeted therapy have yet to be developed. |
2024-07-17 |
2024-07-20 |
Not clear |
| Hiroyuki Ichijo, Nguyen Thi Van Trang, Tomoya Nakamur. Topographic Organization of Glutamatergic and GABAergic Parvalbumin Positive Neurons in the Lateral Habenula. eNeuro. 2024-07-03. PMID:38960707. |
to achieve this, we investigated the proportions of the transmitter machinery in lhb pv neurons, including gabaergic, glutamatergic, serotonergic, cholinergic, and dopaminergic neurotransmitter markers, using transcriptome analysis, mrna in situ hybridization chain reaction, and immunohistochemistry. |
2024-07-03 |
2024-07-10 |
mouse |
| Mie Gangi, Takuma Maruyama, Toshiyuki Ishii, Makoto Kaned. ON and OFF starburst amacrine cells are controlled by distinct cholinergic pathways. The Journal of general physiology. vol 156. issue 8. 2024-06-05. PMID:38836782. |
neither tetrodotoxin, which blocked action potentials, nor ly354740, which blocked neurotransmitter release from sacs, eliminated ach-induced gabaergic feedback in sacs. |
2024-06-05 |
2024-06-07 |
mouse |
| Seong-Eun Lee, Gum Hwa Le. Effects of psoralidin on the expression of glutamate decarboxylases and inhibitory synapse development. Journal of Asian natural products research. 2024-05-16. PMID:38753588. |
gamma-aminobutyric acid (gaba), a major inhibitory neurotransmitter required for excitation/inhibition balance is synthesized by the glutamic acid decarboxylases (gads) in gabaergic neurons. |
2024-05-16 |
2024-05-27 |
Not clear |
| Peeraporn Varinthra, Shameemun Naseer Mohamed Nizarul Anwar, Shu-Ching Shih, Ingrid Y Li. The role of the GABAergic system on insomnia. Tzu chi medical journal. vol 36. issue 2. 2024-04-22. PMID:38645778. |
the gabaergic system is the primary inhibitory neurotransmitter system in the central nervous system. |
2024-04-22 |
2024-04-24 |
Not clear |
| Shubhrat Maheshwari, Aditya Sing. Navigating the Dementia Landscape: Biomarkers and Emerging Therapies. Ageing research reviews. 2024-01-12. PMID:38215913. |
tms has uncovered unique neurophysiological signatures, highlighting impaired plasticity, hyperexcitability, and altered connectivity in ad, while ftd displays differences in neurotransmitter systems, particularly gabaergic and glutamatergic circuits. |
2024-01-12 |
2024-01-15 |
Not clear |
| Aynura Aghayeva, Duygu Gok Yurtseven, Nursel Hasanoglu Akbulut, Ozhan Eyigo. Immunohistochemical determination of the excitatory and inhibitory axonal endings contacting NUCB2/nesfatin-1 neurons. Neuropeptides. vol 103. 2023-12-29. PMID:38157780. |
when the axonal contact of vesicular neurotransmitter transporter proteins was compared between the neurotransmitters, it was determined that the most prominent innervation is gabaergic. |
2023-12-29 |
2024-01-05 |
human |
| Nina-Francesca Parrella, Aron T Hill, Lillian M Dipnall, Yuk Jing Loke, Peter G Enticott, Talitha C For. Inhibitory dysfunction and social processing difficulties in autism: A comprehensive narrative review. Journal of psychiatric research. vol 169. 2023-11-28. PMID:38016393. |
the primary inhibitory neurotransmitter γ-aminobutyric acid (gaba) has a prominent role in regulating neural development and function, with disruption to gabaergic signalling linked to behavioural phenotypes associated with neurodevelopmental disorders, particularly autism. |
2023-11-28 |
2023-12-07 |
Not clear |
| Diego Ruiz-Sobremazas, Mario Ruiz Coca, Miguel Morales-Navas, Rocío Rodulfo-Cárdenas, Caridad López-Granero, Maria Teresa Colomina, Cristian Perez-Fernandez, Fernando Sanchez-Sante. Neurodevelopmental consequences of gestational exposure to particulate matter 10: Ultrasonic vocalizations and gene expression analysis using a bayesian approach. Environmental research. 2023-11-02. PMID:37918762. |
in addition, we were able to detect abnormalities in the expression of genes related to different neurotransmitter systems, such as the gabaergic and monoaminergic systems. |
2023-11-02 |
2023-11-08 |
rat |