| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Claire E Cho, Dahee Jung, Reesha R Pate. Sleepless nights and social plights: medial septum GABAergic hyperactivity in a neuroligin 3-deficient autism model. The Journal of clinical investigation. vol 134. issue 19. 2024-10-01. PMID:39352378. |
sleepless nights and social plights: medial septum gabaergic hyperactivity in a neuroligin 3-deficient autism model. |
2024-10-01 |
2024-10-03 |
Not clear |
| Maxime Lévesque, Fei Ran Li, Siyan Wang, Massimo Avol. Frequency-dependent seizure-suppressing effects of optogenetic activation of septal inhibitory cells in mesial temporal lobe epilepsy. Neurobiology of disease. 2024-07-10. PMID:38986718. |
our results indicate that activation of gabaergic pv-positive neurons in the medial septum exerts seizure-suppressing effects that are frequency-dependent and associated with low rates of fast ripples. |
2024-07-10 |
2024-07-13 |
mouse |
| Jianyu Zhu, Yayue Yang, Lixia Du, Wei Yang, Yachen Yang, Ting Yi, Qiliang Maoying, Yuxia Chu, Yanqing Wang, Wenli M. A regulatory role of the medial septum in the chloroquine-induced acute itch through local GABAergic system and GABAergic pathway to the anterior cingulate cortex. Biochemical and biophysical research communications. vol 721. 2024-05-25. PMID:38795633. |
a regulatory role of the medial septum in the chloroquine-induced acute itch through local gabaergic system and gabaergic pathway to the anterior cingulate cortex. |
2024-05-25 |
2024-05-31 |
Not clear |
| Hou-Hong Li, Yang Liu, Hong-Sheng Chen, Ji Wang, Yu-Ke Li, Yang Zhao, Rui Sun, Jin-Gang He, Fang Wang, Jian-Guo Che. PDGF-BB-Dependent Neurogenesis Buffers Depressive-Like Behaviors by Inhibition of GABAergic Projection from Medial Septum to Dentate Gyrus. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2023-06-16. PMID:37325895. |
pdgf-bb-dependent neurogenesis buffers depressive-like behaviors by inhibition of gabaergic projection from medial septum to dentate gyrus. |
2023-06-16 |
2023-08-14 |
Not clear |
| Rebecca L Openshaw, David M Thomson, Greg C Bristow, Emma J Mitchell, Judith A Pratt, Brian J Morris, Neil Dawso. 16p11.2 deletion mice exhibit compromised fronto-temporal connectivity, GABAergic dysfunction, and enhanced attentional ability. Communications biology. vol 6. issue 1. 2023-05-24. PMID:37225770. |
here we show that mice reproducing this deletion (16p11.2 del mice) have reduced gabaergic interneuron gene expression (decreased parvalbumin mrna in orbitofrontal cortex, and male-specific decreases in gad67 mrna in parietal and insular cortex and medial septum). |
2023-05-24 |
2023-08-14 |
mouse |
| Nelson Espinosa, Alejandra Alonso, Mauricio Caneo, Constanza Moran, Pablo Fuentealb. Optogenetic Suppression of Lateral Septum Somatostatin Neurons Enhances Hippocampus Cholinergic Theta Oscillations and Local Synchrony. Brain sciences. vol 13. issue 1. 2023-01-21. PMID:36671983. |
a small population of somatostatin-expressing gabaergic cells in the lateral septum projects deep into subcortical regions, yet on its way it also targets neighboring medial septum neurons that profusely innervate cortical targets by ascending synaptic pathways. |
2023-01-21 |
2023-08-14 |
mouse |
| Barnabás Kocsis, Sergio Martínez-Bellver, Richárd Fiáth, Andor Domonkos, Katalin Sviatkó, Dániel Schlingloff, Péter Barthó, Tamás F Freund, István Ulbert, Szabolcs Káli, Viktor Varga, Balázs Hangy. Huygens synchronization of medial septal pacemaker neurons generates hippocampal theta oscillation. Cell reports. vol 40. issue 5. 2022-08-04. PMID:35926456. |
episodic learning and memory retrieval are dependent on hippocampal theta oscillation, thought to rely on the gabaergic network of the medial septum (ms). |
2022-08-04 |
2023-08-14 |
mouse |
| Xue Liu, Hongren Huang, Yulin Zhang, Liping Wang, Feng Wan. Sexual Dimorphism of Inputs to the Lateral Habenula in Mice. Neuroscience bulletin. 2022-06-01. PMID:35644002. |
more interestingly, we found a stronger gabaergic projection from the medial septum to the lhb in males than in females. |
2022-06-01 |
2023-08-13 |
mouse |
| Li Shen, Guang-Wei Zhang, Can Tao, Michelle B Seo, Nicole K Zhang, Junxiang J Huang, Li I Zhang, Huizhong W Ta. A bottom-up reward pathway mediated by somatostatin neurons in the medial septum complex underlying appetitive learning. Nature communications. vol 13. issue 1. 2022-03-08. PMID:35256596. |
here, we report that somatostatin (som) subtype of gabaergic neurons in the mouse medial septum complex (ms), but not parvalbumin subtype or glutamatergic neurons, specifically encode reward signals and positive valence. |
2022-03-08 |
2023-08-13 |
mouse |
| R G K Munn, A Freeburn, D P Finn, H C Helle. Hyper-rigid phasic organisation of hippocampal activity but normal spatial properties of CA1 place cells in the Ts65Dn mouse model of Down Syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-01-04. PMID:34980635. |
one of the primary functional differences in ds is thought to be an excess of gabaergic innervation from medial septum (ms) to the hippocampus. |
2022-01-04 |
2023-08-13 |
mouse |
| Yuichi Takeuchi, Márk Harangozó, Lizeth Pedraza, Tamás Földi, Gábor Kozák, Qun Li, Antal Berény. Closed-loop stimulation of the medial septum terminates epileptic seizures. Brain : a journal of neurology. vol 144. issue 3. 2021-08-13. PMID:33501929. |
cell type-specific stimulation revealed that the precisely timed activation of medial septum gabaergic neurons underlaid the effects. |
2021-08-13 |
2023-08-13 |
rat |
| Arnau Sans-Dublanc, Adrià Razzauti, Srinidhi Desikan, Marta Pascual, Hannah Monyer, Carlos Sindre. Septal GABAergic inputs to CA1 govern contextual memory retrieval. Science advances. vol 6. issue 44. 2020-11-14. PMID:33127668. |
γ-aminobutyric acid-releasing (gabaergic) long-range projections from the medial septum (ms) densely innervate the hippocampus, but whether septal inputs regulate memory expression remains elusive. |
2020-11-14 |
2023-08-13 |
Not clear |
| M. Virgili, O. Barnabei, A. Contestabil. Regional- and Age-Specific Neurochemical Alterations in Rats Rendered Microencephalic by Differentially Timed Gestational Methylazoxymethanol Treatment. The European journal of neuroscience. vol 1. issue 6. 2019-11-20. PMID:12106122. |
specific markers for cholinergic (choline acetyltransferase, chat), gabaergic (glutamate decarboxylase, gad), and glutamatergic (d-3h aspartate high affinity uptake) neurons, were measured in several brain regions (cortex, hippocampus, anterior and posterior striatum, medial septum plus nucleus of the diagonal band, globus pallidus) in young and adult microencephalic rats. |
2019-11-20 |
2023-08-12 |
rat |
| Tim James Viney, Minas Salib, Abhilasha Joshi, Gunes Unal, Naomi Berry, Peter Somogy. Shared rhythmic subcortical GABAergic input to the entorhinal cortex and presubiculum. eLife. vol 7. 2019-07-22. PMID:29620525. |
using monosynaptically-restricted retrograde viral tracing in mice, we identified a subcortical gabaergic input from the medial septum that terminated in the entorhinal cortex, with collaterals innervating the dorsal presubiculum. |
2019-07-22 |
2023-08-13 |
mouse |
| Hai-Qin Huo, Zhuang-Yin Qu, Fang Yuan, Lixiang Ma, Lin Yao, Min Xu, Yao Hu, Jing Ji, Anita Bhattacharyya, Su-Chun Zhang, Yan Li. Modeling Down Syndrome with Patient iPSCs Reveals Cellular and Migration Deficits of GABAergic Neurons. Stem cell reports. vol 10. issue 4. 2019-04-23. PMID:29526735. |
such phenotypes were replicated following transplantation of the ds gabaergic progenitors into the mouse medial septum. |
2019-04-23 |
2023-08-13 |
mouse |
| L Stan Leung, Jingyi M. Medial septum modulates hippocampal gamma activity and prepulse inhibition in an N-methyl-d-aspartate receptor antagonist model of schizophrenia. Schizophrenia research. vol 198. 2019-02-07. PMID:28801194. |
the behavioral and electrophysiological disruptions induced by an nmda receptor antagonist can be reduced by inactivation or lesion of gabaergic neurons in the medial septum, deep brain stimulation of the medial septum or nucleus accumbens, or positive modulation of gaba |
2019-02-07 |
2023-08-13 |
Not clear |
| Christina Müller, Stefan Rem. Septo-hippocampal interaction. Cell and tissue research. vol 373. issue 3. 2018-12-11. PMID:29250747. |
in the medial septum, cholinergic, glutamatergic and gabaergic neurons form a highly interconnected local network. |
2018-12-11 |
2023-08-13 |
Not clear |
| Christina Müller, Stefan Rem. Septo-hippocampal interaction. Cell and tissue research. vol 373. issue 3. 2018-12-11. PMID:29250747. |
from there, gabaergic neurons project back to the medial septum and form a feedback loop between the two remote brain areas. |
2018-12-11 |
2023-08-13 |
Not clear |
| Hechen Bao, Brent Asrican, Weidong Li, Bin Gu, Zhexing Wen, Szu-Aun Lim, Isaac Haniff, Charu Ramakrishnan, Karl Deisseroth, Benjamin Philpot, Juan Son. Long-Range GABAergic Inputs Regulate Neural Stem Cell Quiescence and Control Adult Hippocampal Neurogenesis. Cell stem cell. vol 21. issue 5. 2018-06-26. PMID:29100013. |
here, we identify gabaergic projection neurons from the medial septum (ms) as the major afferents to dentate pv interneurons. |
2018-06-26 |
2023-08-13 |
Not clear |
| Pierre-Hervé Luppi, Francesca Billwiller, Patrice For. Selective activation of a few limbic structures during paradoxical (REM) sleep by the claustrum and the supramammillary nucleus: evidence and function. Current opinion in neurobiology. vol 44. 2018-03-01. PMID:28347885. |
further, recent results suggest that tonic activation of limbic cortical neurons during ps is due to projections from glutamate neurons of the claustrum and gaba/glutamate neurons of the supramammillary nucleus while their pacing with theta is induced by projections from gabaergic neurons of the medial septum. |
2018-03-01 |
2023-08-13 |
Not clear |