All Relations between gabaergic and cholinergic

Publication Sentence Publish Date Extraction Date Species
Megan E Barra, Ken Solt, Xin Yu, Brian L Edlo. Restoring consciousness with pharmacologic therapy: Mechanisms, targets, and future directions. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2024-07-17. PMID:39019729. however, the relative contributions of monoaminergic, glutamatergic, cholinergic, gabaergic, and orexinergic neurotransmitter systems to recovery of consciousness after severe brain injury are unknown, and personalized approaches to targeted therapy have yet to be developed. 2024-07-17 2024-07-20 Not clear
Hiroyuki Ichijo, Nguyen Thi Van Trang, Tomoya Nakamur. Topographic Organization of Glutamatergic and GABAergic Parvalbumin Positive Neurons in the Lateral Habenula. eNeuro. 2024-07-03. PMID:38960707. to achieve this, we investigated the proportions of the transmitter machinery in lhb pv neurons, including gabaergic, glutamatergic, serotonergic, cholinergic, and dopaminergic neurotransmitter markers, using transcriptome analysis, mrna in situ hybridization chain reaction, and immunohistochemistry. 2024-07-03 2024-07-10 mouse
Boxuan Li, Shizhe Deng, Hailun Jiang, Weiming Zhu, Bifang Zhuo, Yuzheng Du, Zhihong Men. The mechanistic effects of acupuncture in rodent neurodegenerative disease models: a literature review. Frontiers in neuroscience. vol 18. 2024-03-19. PMID:38500484. here, we reviewed the therapeutic mechanisms of acupuncture at the neural circuit level in movement and cognition disorders, summarizing the influence of acupuncture in the dopaminergic system, glutamatergic system, γ-amino butyric acid-ergic (gabaergic) system, serotonergic system, cholinergic system, and glial cells at the circuit and synaptic levels. 2024-03-19 2024-03-21 Not clear
Yifan Wang, Liana Fasching, Feinan Wu, Anita Huttner, Sabina Berretta, Rosalinda Roberts, James F Leckman, Alexej Abyzov, Flora M Vaccarin. Interneuron loss and microglia activation by transcriptome analyses in the basal ganglia of Tourette syndrome. bioRxiv : the preprint server for biology. 2024-03-11. PMID:38464084. the data reproduced the known cellular composition of the adult human striatum, including a majority of medium spiny neurons (msn) and small populations of gabaergic and cholinergic interneurons. 2024-03-11 2024-03-14 human
Meghan Van Zandt, Deirdre Flanagan, Christopher Pittenge. Sexual dimorphism in the distribution and density of regulatory interneurons in the striatum. bioRxiv : the preprint server for biology. 2024-03-11. PMID:38464268. regulatory interneurons, including cholinergic interneurons (cins) and parvalbumin-expressing gabaergic fast spiking interneurons (fsis), are implicated in human neuropsychiatric disorders such as ts, and ablation of these interneurons produces relevant behavioral pathology in male mice, but not in females. 2024-03-11 2024-03-14 mouse
Yu Han, Jia-Qi Zhang, Ya-Wei Ji, Yi-Wen Luan, Shu-Yi Li, Hui-Zhen Geng, Ying Ji, Cui Yin, Su Liu, Chun-Yi Zhou, Cheng Xia. α4 nicotinic receptors on GABAergic neurons mediate a cholinergic analgesic circuit in the substantia nigra pars reticulata. Acta pharmacologica Sinica. 2024-03-04. PMID:38438581. α4 nicotinic receptors on gabaergic neurons mediate a cholinergic analgesic circuit in the substantia nigra pars reticulata. 2024-03-04 2024-03-07 mouse
Yu Han, Jia-Qi Zhang, Ya-Wei Ji, Yi-Wen Luan, Shu-Yi Li, Hui-Zhen Geng, Ying Ji, Cui Yin, Su Liu, Chun-Yi Zhou, Cheng Xia. α4 nicotinic receptors on GABAergic neurons mediate a cholinergic analgesic circuit in the substantia nigra pars reticulata. Acta pharmacologica Sinica. 2024-03-04. PMID:38438581. the analgesic effects of nachr agonists were mimicked by optogenetic stimulation of cholinergic inputs from the pedunculopontine nucleus (ppn) to the snr, but attenuated upon downregulation of α4 nachrs on snr gabaergic neurons and injection of dihydro-β-erythroidine into the snr. 2024-03-04 2024-03-07 mouse
Yu Han, Jia-Qi Zhang, Ya-Wei Ji, Yi-Wen Luan, Shu-Yi Li, Hui-Zhen Geng, Ying Ji, Cui Yin, Su Liu, Chun-Yi Zhou, Cheng Xia. α4 nicotinic receptors on GABAergic neurons mediate a cholinergic analgesic circuit in the substantia nigra pars reticulata. Acta pharmacologica Sinica. 2024-03-04. PMID:38438581. these results suggest that α4 nachrs on gabaergic neurons mediate a cholinergic analgesic circuit in the snr, and these receptors may be effective therapeutic targets to relieve hyperalgesia in acute and chronic pain, and chronic nicotine exposure. 2024-03-04 2024-03-07 mouse
Elizabeth N Holly, Jamie Galanaugh, Marc V Fuccill. Local regulation of striatal dopamine: A diversity of circuit mechanisms for a diversity of behavioral functions? Current opinion in neurobiology. vol 85. 2024-02-03. PMID:38309106. we first look at historical and recent work demonstrating that striatal circuits interact with dopaminergic terminals to either initiate the release of dopamine or modulate the release of dopamine initiated by spiking in midbrain dopamine neurons, with particular attention to gabaergic and cholinergic local circuit mechanisms. 2024-02-03 2024-02-06 Not clear
Javed Iqbal, Geng-Di Huang, Yan-Xue Xue, Mei Yang, Xiao-Jian Ji. The neural circuits and molecular mechanisms underlying fear dysregulation in posttraumatic stress disorder. Frontiers in neuroscience. vol 17. 2023-12-20. PMID:38116070. we further describe different molecular mechanisms, including gabaergic, glutamatergic, cholinergic, and neurotropic signaling, responsible for the structural and functional changes during fear acquisition and fear extinction processes in ptsd. 2023-12-20 2023-12-23 Not clear
Megan K Gautier, Christy M Kelley, Sang Han Lee, Melissa J Alldred, John McDaid, Elliott J Mufson, Grace E Stutzmann, Stephen D Ginsber. Maternal choline supplementation protects against age-associated cholinergic and GABAergic basal forebrain neuron degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease. Neurobiology of disease. vol 188. 2023-11-04. PMID:37890559. maternal choline supplementation protects against age-associated cholinergic and gabaergic basal forebrain neuron degeneration in the ts65dn mouse model of down syndrome and alzheimer's disease. 2023-11-04 2023-11-08 mouse
Elliot Wegman, Marlena Wosiski-Kuhn, Yu Lu. The dual role of striatal interneurons: circuit modulation and trophic support for the basal ganglia. Neural regeneration research. vol 19. issue 6. 2023-10-31. PMID:37905876. this review aims to summarize recent findings regarding the role of striatal cholinergic and gabaergic interneurons in providing circuit modulation to the basal ganglia in both homeostatic and disease conditions. 2023-10-31 2023-11-08 Not clear
Daniela Colita, Daiana Burdusel, Daniela Glavan, Dirk M Hermann, Cezar-Ivan Colită, Eugen Colita, Ion Udristoiu, Aurel Popa-Wagne. Molecular mechanisms underlying major depressive disorder and post-stroke affective disorders. Journal of affective disorders. 2023-10-12. PMID:37827260. the major contributor to psd is the stroke lesion location, which can involve the disruption of the serotoninergic, dopaminergic, glutamatergic, gabaergic, or cholinergic pathways. 2023-10-12 2023-10-15 Not clear
C Bañuelos, J R Kittleson, K H LaNasa, C S Galiano, S M Roth, E J Perez, J M Long, M T Roberts, S Fong, P R Rap. Cognitive Aging and the Primate Basal Forebrain Revisited: Disproportionate GABAergic Vulnerability Revealed. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-10-05. PMID:37798131. although a long history of research on neurocognitive aging has focused on the role of the cholinergic basal forebrain system, intermingled gabaergic cells are numerically as prominent and well-positioned to regulate the activity of their cortical projection targets, including the hippocampus and prefrontal cortex. 2023-10-05 2023-10-07 monkey
Sara Mostafalou, Mohammad Abdollah. The susceptibility of humans to neurodegenerative and neurodevelopmental toxicities caused by organophosphorus pesticides. Archives of toxicology. 2023-10-03. PMID:37787774. apart from inhibiting the cholinesterase enzyme, op compounds are believed to cause other pathological mechanisms at both the extracellular level (cholinergic, serotonergic, dopaminergic, glutamatergic, and gabaergic synapses) and the intracellular level (oxidative stress, mitochondrial dysfunction, inflammation, autophagy, and apoptosis) that contribute to these disorders. 2023-10-03 2023-10-07 human
Joseph V Martin, Pradip K Sarka. Nongenomic roles of thyroid hormones and their derivatives in adult brain: are these compounds putative neurotransmitters? Frontiers in endocrinology. vol 14. 2023-09-13. PMID:37701902. furthermore, thyronines bind specifically to other defined neurotransmitter receptors, including gabaergic, catecholaminergic, glutamatergic, serotonergic and cholinergic systems. 2023-09-13 2023-10-07 Not clear
Natalia Lozovaya, Sanaz Eftekhari, Constance Hammon. The early excitatory action of striatal cholinergic-GABAergic microcircuits conditions the subsequent GABA inhibitory shift. Communications biology. vol 6. issue 1. 2023-07-14. PMID:37452171. cholinergic interneurons of the striatum play a role in action selection and associative learning by activating local gabaergic inhibitory microcircuits. 2023-07-14 2023-08-14 Not clear
Mallikarjuna Nimgampalle, Harshini Chakravarthy, Sapana Sharma, Shruti Shree, Anoop Ramachandra Bhat, Jangampalli Adi Pradeepkiran, Vasudharani Devanatha. Neurotransmitter Systems in the Etiology of Major Neurological Disorders: Emerging Insights and Therapeutic Implications. Ageing research reviews. 2023-06-29. PMID:37385351. neurotransmitter systems are classified as cholinergic, glutamatergic, gabaergic, dopaminergic, serotonergic, histaminergic, or aminergic systems, depending on the type of neurotransmitter secreted by the neuron, allowing effector organs to carry out specific functions by sending nerve impulses. 2023-06-29 2023-08-14 Not clear
Meng Zhang, Li-Yuan Liu, Yong Xu, Wen-Zhi Wang, Nian-Zhuang Qiu, Fang-Fang Zhang, Feng Zhang, Xiao-Dan Wang, Wei Chen, Xiao-Yan Xu, Yong-Feng Gao, Mei-Hua Chen, Yu-Qin Li, Han-Ting Zhang, Hao Wan. Imbalance of multiple neurotransmitter pathways leading to depression-like behavior and cognitive dysfunction in the triple transgenic mouse model of Alzheimer disease. Metabolic brain disease. 2023-05-31. PMID:37256468. the complex and diverse mechanism appears not only relevant to the imbalance of multiple neurotransmitter pathways, including the transmitters and receptors of the monoaminergic, gabaergic, histaminergic, and cholinergic systems, but also related to the changes in l-arginine and creb signaling molecules. 2023-05-31 2023-08-14 mouse
Melissa J Alldred, Harshitha Pidikiti, Adriana Heguy, Panos Roussos, Stephen D Ginsber. Basal forebrain cholinergic neurons are vulnerable in a mouse model of Down syndrome and their molecular fingerprint is rescued by maternal choline supplementation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 6. 2023-05-16. PMID:37191946. leveraging multiple bioinformatic analysis programs on differentially expressed genes (degs) by genotype and diet, we identified key canonical pathways and altered physiological functions within ts65dn msn bfcns, which were attenuated by mcs in trisomic offspring, including the cholinergic, glutamatergic and gabaergic pathways. 2023-05-16 2023-08-14 mouse