| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joanna M Karasinska, Susan R George, Regina Cheng, Brian F O'Dow. Deletion of dopamine D1 and D3 receptors differentially affects spontaneous behaviour and cocaine-induced locomotor activity, reward and CREB phosphorylation. The European journal of neuroscience. vol 22. issue 7. 2006-01-23. PMID:16197514. |
co-localization of dopamine d1 and d3 receptors in striatal neurons suggests that these two receptors interact at a cellular level in mediating dopaminergic function including psychostimulant-induced behaviour. |
2006-01-23 |
2023-08-12 |
mouse |
| Rocío M de Pablos, Antonio J Herrera, Mayka Tomás-Camardiel, Alberto Machado, Josefina Can. Deprenyl enhances the striatal neuronal damage produced by quinolinic acid. Brain research. Molecular brain research. vol 141. issue 1. 2006-01-23. PMID:16202473. |
these effects are produced by deprenyl potentiation of dopamine actions since dopamine depletion produced by previous injection of the dopaminergic toxin 6-hydroxydopamine within the medial forebrain bundle overcomes deprenyl effects and the involvement of dopamine in the quinolinic acid-induced toxicity in striatum. |
2006-01-23 |
2023-08-12 |
Not clear |
| b' Leonid Yavich, Mari Oksman, Heikki Tanila, Petri Kerokoski, Mikko Hiltunen, Thomas van Groen, Jukka Puoliv\\xc3\\xa4li, Pekka T M\\xc3\\xa4nnist\\xc3\\xb6, Arturo Garc\\xc3\\xada-Horsman, Ewen MacDonald, Konrad Beyreuther, Tobias Hartmann, Pekka J\\xc3\\xa4k\\xc3\\xa4l\\xc3\\xa. Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human alpha-synuclein. Neurobiology of disease. vol 20. issue 2. 2006-01-23. PMID:16242637.' |
in vivo voltammetry showed that a30p mice responded to longer stimulation of the ascending dopaminergic pathways with less dopamine release in striatum and had a slower rate of dopamine decline after repeated stimulations or after alpha-methyl-p-tyrosine-hcl treatment. |
2006-01-23 |
2023-08-12 |
mouse |
| J Jankovic, S Chen, W D L. The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease. Progress in neurobiology. vol 77. issue 1-2. 2006-01-20. PMID:16243425. |
nurr1 interacts with other factors critical for the survival of mensencephalic dopaminergic neurons and it appears to regulate the expression of tyrosine hydroxylase (th), dopamine transporter (dat), vesicular monoamine transporter 2 (vmat2), and l-aromatic amino acid decarboxylase (aadc), all of which are important in the synthesis and storage of dopamine. |
2006-01-20 |
2023-08-12 |
mouse |
| Bethany N Sotak, Thomas S Hnasko, Siobhan Robinson, Erik J Kremer, Richard D Palmite. Dysregulation of dopamine signaling in the dorsal striatum inhibits feeding. Brain research. vol 1061. issue 2. 2006-01-17. PMID:16226228. |
adequate feeding by dd mice can be achieved by daily administration of l-3,4-dihydroxyphenylalanine (l-dopa), a precursor of dopamine, which can be taken up by dopaminergic neurons, converted to dopamine, and released in a regulated manner. |
2006-01-17 |
2023-08-12 |
mouse |
| A Winogrodzka, J Booij, E Ch Wolter. Disease-related and drug-induced changes in dopamine transporter expression might undermine the reliability of imaging studies of disease progression in Parkinson's disease. Parkinsonism & related disorders. vol 11. issue 8. 2006-01-17. PMID:16257254. |
dopamine transporter (dat) scintigraphy with single photon emission computed tomography (spect) has been used to assess the dopaminergic function in pd. |
2006-01-17 |
2023-08-12 |
Not clear |
| R Lanzenberger, S Kaspe. [Neuroimaging in schizophrenia]. Fortschritte der Neurologie-Psychiatrie. vol 73 Suppl 1. 2006-01-05. PMID:16270245. |
several pet and spect studies have shown a pronounced increase of amphetamine-induced dopamine release as well as decrease of ampt-induced dopamine depletion in drug-naive schizophrenic patients, indicating a dysregulation of dopaminergic neurotransmission. |
2006-01-05 |
2023-08-12 |
Not clear |
| D Hill, M Ikaiddi, E Mazzio, K F Solima. The neurochemical basis for the behavioral effects of triadimefon. Annals of the New York Academy of Sciences. vol 914. 2006-01-04. PMID:11085334. |
adaptative biochemical changes in dopaminergic function were examined after both acute (100 mg/kg) and repeated administration of tdf (100 mg/kg, 14 days) by examining [3h]dopamine (da) uptake and da release in both striatal (st) and nucleus accumbens (na) tissue. |
2006-01-04 |
2023-08-12 |
rat |
| J Gomes-da-Silva, A Perez-Rosado, de Miguel R, J Fernandez-Ruiz, M C Silva, M A Tavare. Neonatal methamphetamine in the rat: evidence for gender-specific differences upon tyrosine hydroxylase enzyme in the dopaminergic nigrostriatal system. Annals of the New York Academy of Sciences. vol 914. 2006-01-04. PMID:11085342. |
these results support the evidence that meth exposure during the first month of life in the rat has a gender-specific stimulatory effect upon the maturation of th, the key enzyme for dopamine biosynthesis in the nigrostriatal dopaminergic system. |
2006-01-04 |
2023-08-12 |
rat |
| J I Udo de Haes, R Kortekaas, A Van Waarde, R P Maguire, J Pruim, J A den Boe. Assessment of methylphenidate-induced changes in binding of continuously infused [(11)C]-raclopride in healthy human subjects: correlation with subjective effects. Psychopharmacology. vol 183. issue 3. 2006-01-04. PMID:16220327. |
it has been shown that information on endogenous dopamine (da) release can be obtained noninvasively by combining positron emission tomography with a dopaminergic challenge. |
2006-01-04 |
2023-08-12 |
human |
| M Picciolo, D Gigante, A Nunziat. [Nicotine addiction and current therapy of smoking cessation]. La Clinica terapeutica. vol 156. issue 4. 2006-01-04. PMID:16342517. |
nicotine is defined as substance which provokes addiction because it creates both physiological and biochemical modifications in the nervous system stimulating the activity of dopaminergic neurons releasing dopamine in the areas of the brain that control pleasure. |
2006-01-04 |
2023-08-12 |
Not clear |
| Matthew J LaVoie, Beth L Ostaszewski, Andreas Weihofen, Michael G Schlossmacher, Dennis J Selko. Dopamine covalently modifies and functionally inactivates parkin. Nature medicine. vol 11. issue 11. 2005-12-28. PMID:16227987. |
here we report that the neurotransmitter dopamine covalently modifies parkin in living dopaminergic cells, a process that increases parkin insolubility and inactivates its e3 ubiquitin ligase function. |
2005-12-28 |
2023-08-12 |
human |
| Matthew J LaVoie, Beth L Ostaszewski, Andreas Weihofen, Michael G Schlossmacher, Dennis J Selko. Dopamine covalently modifies and functionally inactivates parkin. Nature medicine. vol 11. issue 11. 2005-12-28. PMID:16227987. |
these findings show a vulnerability of parkin to modification by dopamine, the principal transmitter lost in parkinson disease, suggesting a mechanism for the progressive loss of parkin function in dopaminergic neurons during aging and sporadic parkinson disease. |
2005-12-28 |
2023-08-12 |
human |
| L Kent, E Green, Z Hawi, A Kirley, F Dudbridge, N Lowe, R Raybould, K Langley, N Bray, M Fitzgerald, M J Owen, M C O'Donovan, M Gill, A Thapar, N Craddoc. Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD. Molecular psychiatry. vol 10. issue 10. 2005-12-23. PMID:15940292. |
bdnf is a member of the neurotrophin family and is involved in the survival and differentiation of dopaminergic neurons in the developing brain (of relevance because drugs that block the dopamine transporter can be effective therapeutically). |
2005-12-23 |
2023-08-12 |
human |
| S Jourdain, M Morissette, N Morin, T Di Paol. Oestrogens prevent loss of dopamine transporter (DAT) and vesicular monoamine transporter (VMAT2) in substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice. Journal of neuroendocrinology. vol 17. issue 8. 2005-12-23. PMID:16011487. |
17beta-oestradiol treatment prevented the loss of these dopaminergic markers, as well as striatal concentrations of dopamine, dopac and hva. |
2005-12-23 |
2023-08-12 |
mouse |
| I G Sil'ki. [A role of the basal ganglia in the occurrence of visual hallucinations (a hypothetical mechanism)]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 55. issue 5. 2005-12-23. PMID:16316020. |
according to our model, cannabinoids, opioids and ketamine may lead to hallucinations due to their promotional role in the ltd of cortical inputs to gabaergic spiny cells of striatal striosomes projecting to dopaminergic neurons, disinhibition of the lasts, and increase in striatal dopamine concentration. |
2005-12-23 |
2023-08-12 |
Not clear |
| O Giorgi, G Piras, D Lecca, M G Cord. Differential activation of dopamine release in the nucleus accumbens core and shell after acute or repeated amphetamine injections: a comparative study in the Roman high- and low-avoidance rat lines. Neuroscience. vol 135. issue 3. 2005-12-22. PMID:16154292. |
we show that (1) in naïve rats, amphetamine caused a larger increment in dopamine output in the nucleus accumbens-shell vs the nucleus accumbens-core only in the roman high-avoidance line; (2) repeated amphetamine elicits behavioral sensitization in roman high-avoidance, but not roman low-avoidance, rats; (3) in sensitized roman high-avoidance rats, amphetamine provokes a larger increment in dopamine output in the nucleus accumbens-core, and an attenuated dopaminergic response in the nucleus accumbens-shell, as compared with roman high-avoidance rats repeatedly treated with saline; and (4) such neurochemical changes are not observed in the mesoaccumbens dopaminergic system of the sensitization-resistant roman low-avoidance line. |
2005-12-22 |
2023-08-12 |
rat |
| Hans C Lou, Markus Nowak, Troels W Kjae. The mental self. Progress in brain research. vol 150. 2005-12-22. PMID:16186024. |
the inclusion of the striatum and our subsequent finding of increased striatal dopamine binding to d2 receptors during meditation suggested dopaminergic regulation of this circuit. |
2005-12-22 |
2023-08-12 |
Not clear |
| Yoko Matsuoka, Tomoyuki Furuyashiki, Kiyofumi Yamada, Taku Nagai, Haruhiko Bito, Yasuhiro Tanaka, Shiho Kitaoka, Fumitaka Ushikubi, Toshitaka Nabeshima, Shuh Narumiy. Prostaglandin E receptor EP1 controls impulsive behavior under stress. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 44. 2005-12-21. PMID:16247016. |
dopamine turnover in the frontal cortex and striatum was increased in ptger1(-/-) mice, and administration of dopaminergic antagonists corrected their behavioral phenotype. |
2005-12-21 |
2023-08-12 |
mouse |
| Yoko Hirata, Toshiharu Nagats. Rotenone and CCCP inhibit tyrosine hydroxylation in rat striatal tissue slices. Toxicology. vol 216. issue 1. 2005-12-20. PMID:16115719. |
previous studies performed in rat striatal slices have shown that dopaminergic neurotoxins, mptp and manganese, inhibit tyrosine hydroxylation, a rate-limiting step of dopamine biosynthesis. |
2005-12-20 |
2023-08-12 |
rat |