| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Carsten Möller, Wolfgang H Oerte. Pramipexole in the treatment of Parkinson's disease: new developments. Expert review of neurotherapeutics. vol 5. issue 5. 2006-04-20. PMID:16162081. |
clinicians may favor pramipexole over other dopamine agonists because of its suggested higher tolerability with respect to peripheral dopaminergic side effects. |
2006-04-20 |
2023-08-12 |
Not clear |
| Claire Henchcliffe, H Christian Schumacher, F Tuna Burgu. Recent advances in Parkinson's disease therapy: use of monoamine oxidase inhibitors. Expert review of neurotherapeutics. vol 5. issue 6. 2006-04-18. PMID:16274338. |
monoamine oxidase inhibitors inhibit dopamine metabolism and are therefore effective in treating parkinson's disease, a condition associated with progressive striatal dopamine deficiency secondary to degeneration of dopaminergic neurons in the substantia nigra. |
2006-04-18 |
2023-08-12 |
Not clear |
| Anne Tammimäki, Kirsi Pietilä, Helena Raattamaa, Liisa Ahte. Effect of quinpirole on striatal dopamine release and locomotor activity in nicotine-treated mice. European journal of pharmacology. vol 531. issue 1-3. 2006-04-18. PMID:16442094. |
thus, the changes occurring in the sensitivity of d2-like dopamine receptors probably play a minor role in regulating the dopaminergic transmission during long-term nicotine administration. |
2006-04-18 |
2023-08-12 |
mouse |
| Vesna Sossi, Raúl de la Fuente-Fernández, Michael Schulzer, John Adams, Jon Stoess. Age-related differences in levodopa dynamics in Parkinson's: implications for motor complications. Brain : a journal of neurology. vol 129. issue Pt 4. 2006-04-17. PMID:16476675. |
treatment-related motor complications in parkinson's disease have been previously linked to disease-induced pre-synaptic alterations: dopaminergic denervation and changes in dopamine (da) release patterns. |
2006-04-17 |
2023-08-12 |
Not clear |
| B Jill Venton, Andrew T Seipel, Paul E M Phillips, William C Wetsel, Daniel Gitler, Paul Greengard, George J Augustine, R Mark Wightma. Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 12. 2006-04-14. PMID:16554471. |
cocaine enhanced the levels of striatal dopamine produced by electrical stimulation of dopaminergic neurons. |
2006-04-14 |
2023-08-12 |
mouse |
| Hélène N David, Marc Ansseau, Jacques H Abrain. Dopamine-glutamate reciprocal modulation of release and motor responses in the rat caudate-putamen and nucleus accumbens of "intact" animals. Brain research. Brain research reviews. vol 50. issue 2. 2006-04-12. PMID:16278019. |
the effects of dopaminergic and glutamatergic receptor selective agonists and antagonists on dopamine and glutamate release as well on motor responses are analyzed in the entire striatum, by reviewing both in vitro and in vivo data. |
2006-04-12 |
2023-08-12 |
rat |
| S A Lloyd, C J Faherty, R J Smeyn. Adult and in utero exposure to cocaine alters sensitivity to the Parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neuroscience. vol 137. issue 3. 2006-04-12. PMID:16298078. |
since synaptic dopamine can rapidly oxidize to form free radicals, it was hypothesized that exposure to this drug might produce damage in dopaminergic systems such as the substantia nigra pars compacta, damage to which is a hallmark of parkinson's disease. |
2006-04-12 |
2023-08-12 |
mouse |
| S Theodore, W A Cass, W F Marago. Methamphetamine and human immunodeficiency virus protein Tat synergize to destroy dopaminergic terminals in the rat striatum. Neuroscience. vol 137. issue 3. 2006-04-12. PMID:16338084. |
dysfunction of the dopaminergic system accompanied by loss of dopamine in the striatum is a major feature of human immunodeficiency virus-1-associated dementia. |
2006-04-12 |
2023-08-12 |
human |
| Jose J Mateos, Francisco Lomeña, Eduardo Parellada, Mireia Font, Emili Fernandez, Javier Pavia, Alberto Prats, Francisca Pons, Miquel Bernard. Decreased striatal dopamine transporter binding assessed with [123I] FP-CIT in first-episode schizophrenic patients with and without short-term antipsychotic-induced parkinsonism. Psychopharmacology. vol 181. issue 2. 2006-04-10. PMID:15830229. |
the dopaminergic nigrostriatal pathway is involved in the movement control, so the study of the dopamine transporter (dat) could be of great value to determine its implication in the appearance of dip. |
2006-04-10 |
2023-08-12 |
Not clear |
| Danyang Liu, Håkan V Wikström, Durk Dijkstra, Jan B de Vries, Bastiaan J Venhui. Extremely potent orally active benzo[g]quinoline analogue of the dopaminergic prodrug: 1-propyl-trans-2,3,4,4a,5,7,8,9,10,10a-decahydro-1H-benzo-[g]quinolin-6-one [corrected]. Journal of medicinal chemistry. vol 49. issue 4. 2006-04-10. PMID:16480286. |
enone prodrugs of dopaminergic catecholamines represent a new type of prodrug in the research area of dopamine agonists. |
2006-04-10 |
2023-08-12 |
Not clear |
| Sarah E McCallum, Neeraja Parameswaran, Tanuja Bordia, Hong Fan, Rachel F Tyndale, J William Langston, J Michael McIntosh, Maryka Qui. Increases in alpha4* but not alpha3*/alpha6* nicotinic receptor sites and function in the primate striatum following chronic oral nicotine treatment. Journal of neurochemistry. vol 96. issue 4. 2006-04-06. PMID:16412091. |
these divergent actions of chronic nicotine treatment on alpha4* versus alpha6* nachrs, as well as effects on dopamine uptake, allow for a complex control of striatal activity to maintain dopaminergic function. |
2006-04-06 |
2023-08-12 |
Not clear |
| Mauro Fasano, Bruno Bergamasco, Leonardo Lopian. Modifications of the iron-neuromelanin system in Parkinson's disease. Journal of neurochemistry. vol 96. issue 4. 2006-04-06. PMID:16417570. |
the occurrence of dopamine (and all the enzymatic machinery required for dopamine synthesis, re-uptake and disposal) and neuromelanin, and a large amount of iron ions that interact with them, makes dopaminergic nigral neurones peculiarly susceptible to oxidative stress conditions that, in turn, may become amplified by the iron-neuromelanin system itself. |
2006-04-06 |
2023-08-12 |
Not clear |
| Sarah C Woolley, Bert O'Malley, John Lydon, David Crew. Genotype differences in behavior and tyrosine hydroxylase expression between wild-type and progesterone receptor knockout mice. Behavioural brain research. vol 167. issue 2. 2006-04-04. PMID:16413068. |
thus, it appears that pr deletion affects the display of sexual behavior and its modulation by dopamine, as well as the differentiation of dopaminergic cells and the plasticity of those cells in response to social environment and behavioral experience. |
2006-04-04 |
2023-08-12 |
mouse |
| Jun Lu, Thomas C Jhou, Clifford B Sape. Identification of wake-active dopaminergic neurons in the ventral periaqueductal gray matter. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 1. 2006-03-31. PMID:16399687. |
recent evidence suggests that dopamine plays an important role in arousal, but the location of the dopaminergic neurons that may regulate arousal remains unclear. |
2006-03-31 |
2023-08-12 |
rat |
| Katsuhiko Sakamoto, Cuimei Liu, Manami Kasamatsu, P Michael Iuvone, Gianluca Tosin. Intraocular injection of kainic acid does not abolish the circadian rhythm of arylalkylamine N-acetyltransferase mRNA in rat photoreceptors. Molecular vision. vol 12. 2006-03-31. PMID:16518309. |
recent studies have suggested that retinal dopaminergic neurons contain a circadian pacemaker, and dopamine is the neurotransmitter that drives circadian rhythmicity in the mammalian retina. |
2006-03-31 |
2023-08-12 |
rat |
| Renee M Miller, Gretchen L Kiser, T M Kaysser-Kranich, Randall J Lockner, Chockalingam Palaniappan, Howard J Federof. Robust dysregulation of gene expression in substantia nigra and striatum in Parkinson's disease. Neurobiology of disease. vol 21. issue 2. 2006-03-29. PMID:16143538. |
we hypothesize that specific differential gene expression underlies important pathogenic processes in parkinson's disease, which is characterized by the gradual loss of dopaminergic neurons in the substantia nigra and consequent loss of dopamine in the striatum. |
2006-03-29 |
2023-08-12 |
human |
| Elena H Chartoff, Mark S Szczypka, Richard D Palmiter, Daniel M Dors. Endogenous neurotensin attenuates dopamine-dependent locomotion and stereotypy. Brain research. vol 1022. issue 1-2. 2006-03-23. PMID:15353215. |
to explore the interaction of nt with the dopamine system, we utilized mice with a targeted deletion of dopamine synthesis specifically in dopaminergic neurons. |
2006-03-23 |
2023-08-12 |
mouse |
| Giuseppe Blasi, Venkata S Mattay, Alessandro Bertolino, Brita Elvevåg, Joseph H Callicott, Saumitra Das, Bhaskar S Kolachana, Michael F Egan, Terry E Goldberg, Daniel R Weinberge. Effect of catechol-O-methyltransferase val158met genotype on attentional control. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 20. 2006-03-23. PMID:15901785. |
evidence indicates that dopamine enhances the neurophysiological signal-to-noise ratio and that dopaminergic tone in the frontal cortex is critically dependent on catechol-o-methyltransferase (comt). |
2006-03-23 |
2023-08-12 |
Not clear |
| Shu Watanabe, Koichi Fusa, Koji Takada, Yuri Aono, Tadashi Saigusa, Noriaki Koshikawa, Alexander R Cool. Effects of alpha-methyl-p-tyrosine on extracellular dopamine levels in the nucleus accumbens and the dorsal striatum of freely moving rats. Journal of oral science. vol 47. issue 4. 2006-03-16. PMID:16415562. |
alpha-methyl-p-tyrosine (ampt) is known to inhibit the formation of dopamine (da) in the cytosol of dopaminergic neurons and is therefore used to study the role of the cytosolic da pools. |
2006-03-16 |
2023-08-12 |
rat |
| Takashi Yamada, Takehiko Terashima, Tsutomu Okubo, Lekh Raj Juneja, Hidehiko Yokogosh. Effects of theanine, r-glutamylethylamide, on neurotransmitter release and its relationship with glutamic acid neurotransmission. Nutritional neuroscience. vol 8. issue 4. 2006-03-16. PMID:16493792. |
l-trans-2,4-pdc or theanine perfusion into the brain striatum caused dopamine release from dopaminergic neurons. |
2006-03-16 |
2023-08-12 |
rat |