| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sung Yul Kim, Kyou Chan Choi, Min Seok Chang, Myoung Hwan Kim, Sa Yong Kim, Young-Soon Na, Jong Eun Lee, Byung Kwan Jin, Bong-Hee Lee, Ja-Hyun Bai. The dopamine D2 receptor regulates the development of dopaminergic neurons via extracellular signal-regulated kinase and Nurr1 activation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 17. 2006-05-23. PMID:16641236. |
the dopamine d2 receptor regulates the development of dopaminergic neurons via extracellular signal-regulated kinase and nurr1 activation. |
2006-05-23 |
2023-08-12 |
mouse |
| Sung Yul Kim, Kyou Chan Choi, Min Seok Chang, Myoung Hwan Kim, Sa Yong Kim, Young-Soon Na, Jong Eun Lee, Byung Kwan Jin, Bong-Hee Lee, Ja-Hyun Bai. The dopamine D2 receptor regulates the development of dopaminergic neurons via extracellular signal-regulated kinase and Nurr1 activation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 17. 2006-05-23. PMID:16641236. |
in mice lacking the dopamine d2 receptor (d2r-/-), stereological cell counting analysis showed that the number of mesencephalic tyrosine hydroxylase (th) cells was significantly low during ontogeny, compared with that observed in wild-type (wt) mice, thereby indicating an alteration in dopaminergic neuronal development in the absence of d2r. |
2006-05-23 |
2023-08-12 |
mouse |
| Maryka Quik, Li Chen, Neeraja Parameswaran, Xinmin Xie, J William Langston, Sarah E McCallu. Chronic oral nicotine normalizes dopaminergic function and synaptic plasticity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned primates. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 17. 2006-05-23. PMID:16641249. |
long-term nicotine administration also attenuated the enhanced k(+)-evoked fractional dopamine release from synaptosomes of mptp-lesioned animals, suggesting that nicotine treatment had a generalized effect on dopaminergic function. |
2006-05-23 |
2023-08-12 |
monkey |
| Remco H S Westerin. Targeting exocytosis: ins and outs of the modulation of quantal dopamine release. CNS & neurological disorders drug targets. vol 5. issue 1. 2006-05-22. PMID:16613554. |
dopaminergic neurotransmission is mediated by the vesicular release of dopamine (da), i.e. |
2006-05-22 |
2023-08-12 |
Not clear |
| Mahmoud M El-Mas, Mahmoud M Mohy El-Din, Sahar M El-Gowilly, Fouad M Sharab. The alpha1-adrenergic receptor not the DA(1)-dopaminergic receptor mediates cyclosporine-SKF38393 renovascular interaction. Canadian journal of physiology and pharmacology. vol 83. issue 12. 2006-05-17. PMID:16462913. |
in this study, we investigated the effect of acute exposure to cyclosporine a (cya) on renal vasodilations evoked by the da(1) dopaminergic agonist skf38393 and whether dopamine da(1) receptors are directly involved in the interaction. |
2006-05-17 |
2023-08-12 |
rat |
| Shao-Ping Ji, Yun Zhang, Jamie Van Cleemput, Wen Jiang, Mingxia Liao, Lei Li, Qi Wan, Jon R Backstrom, Xia Zhan. Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse. Nature medicine. vol 12. issue 3. 2006-05-17. PMID:16474401. |
we showed the probable existence of pten:5-ht2cr complexes in putative dopaminergic neurons in the rat ventral tegmental area (vta), a brain region in which virtually all abused drugs exert rewarding effects by activating its dopamine neurons. |
2006-05-17 |
2023-08-12 |
rat |
| Irene Vourliotaki, Ingrid Elizabeth Bonapart, Catherine Stamataki, Eva-Maria Tsapakis, Catherine Saridak. A case of a prolactinoma resistant to dopamine agonists. Hormones (Athens, Greece). vol 4. issue 3. 2006-05-17. PMID:16613827. |
therefore, either the dose of the dopamine agonists was not toxic enough for the mesolimbic dopaminergic pathway to be activated or the patient was dopamine-resistant in this pathway as well. |
2006-05-17 |
2023-08-12 |
Not clear |
| David S Segal, Ronald Kuczenski, Meghan L O'Neil, William P Melega, Arthur K Ch. Prolonged exposure of rats to intravenous methamphetamine: behavioral and neurochemical characterization. Psychopharmacology. vol 180. issue 3. 2006-05-16. PMID:15959831. |
these data are discussed in terms of damage to dopamine terminals and compensatory adjustments in mechanisms maintaining functional dopaminergic transmission. |
2006-05-16 |
2023-08-12 |
human |
| Stephen Sammut, Alexander Dec, Darrion Mitchell, John Linardakis, Maria Ortiguela, Anthony R Wes. Phasic dopaminergic transmission increases NO efflux in the rat dorsal striatum via a neuronal NOS and a dopamine D(1/5) receptor-dependent mechanism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 3. 2006-05-12. PMID:16012530. |
phasic dopaminergic transmission increases no efflux in the rat dorsal striatum via a neuronal nos and a dopamine d(1/5) receptor-dependent mechanism. |
2006-05-12 |
2023-08-12 |
rat |
| Steven J Garlow, Ericka Boone, Becky Kinkead, Charles B Nemerof. Genetic analysis of the hypothalamic neurotensin system. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 3. 2006-05-12. PMID:16123747. |
the ntta qtl on chromosome 9 includes the dopamine d2 receptor (drd2) gene and qtl involved in responses to dopaminergic agents (hts), antipsychotics (hpic1) and cocaine (cocrb8), and ethanol (etohc3). |
2006-05-12 |
2023-08-12 |
mouse |
| Christophe Wersinger, Anita Sidh. An inflammatory pathomechanism for Parkinson's disease? Current medicinal chemistry. vol 13. issue 5. 2006-05-10. PMID:16515523. |
parkinson's disease (pd) is a slowly progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (snpc), striatal dopamine deficiency and appearance of lewy bodies. |
2006-05-10 |
2023-08-12 |
Not clear |
| Gabriel D Fortin, Catherine C Desrosiers, Nobuharu Yamaguchi, Louis-Eric Trudea. Basal somatodendritic dopamine release requires snare proteins. Journal of neurochemistry. vol 96. issue 6. 2006-05-10. PMID:16539689. |
dopaminergic neurons have the capacity to release dopamine not only from their axon terminals, but also from their somatodendritic compartment. |
2006-05-10 |
2023-08-12 |
rat |
| Silvina L Diaz, Alma K Kemmling, Modesto C Rubio, Graciela N Baleri. Morphine withdrawal syndrome: involvement of the dopaminergic system in prepubertal male and female mice. Pharmacology, biochemistry, and behavior. vol 82. issue 4. 2006-05-09. PMID:16325246. |
considering that the influence of the dopaminergic system on these differences is unclear, we analyzed dopamine (da) and dihydroxyphenylacetic-acid (dopac) brain levels during naloxone (nal)-precipitated withdrawal as well as the involvement of d(1) and d(2) receptors in the expression of mor withdrawal in either sex. |
2006-05-09 |
2023-08-12 |
mouse |
| Morimitsu Fujii, Kazuo Umezawa, Akiko Arat. Dopamine desynchronizes the pace-making neuronal activity of rat respiratory rhythm generation. The European journal of neuroscience. vol 23. issue 4. 2006-05-09. PMID:16519666. |
the dopaminergic suppression of pre-i neurons was mimicked by a dopamine d(4) receptor agonist, pd168077. |
2006-05-09 |
2023-08-12 |
rat |
| Morimitsu Fujii, Kazuo Umezawa, Akiko Arat. Dopamine desynchronizes the pace-making neuronal activity of rat respiratory rhythm generation. The European journal of neuroscience. vol 23. issue 4. 2006-05-09. PMID:16519666. |
these results show that dopaminergic respiratory rhythm depression is due to dispersion of synchronized pre-i driving of i neurons caused by dopamine d(4) receptor stimulation of pre-i neurons. |
2006-05-09 |
2023-08-12 |
rat |
| Keiko Koga, Atsushi Mori, Satoshi Ohashi, Naoki Kurihara, Hisashi Kitagawa, Makoto Ishikawa, Yasuhide Mitsumoto, Masami Naka. H MRS identifies lactate rise in the striatum of MPTP-treated C57BL/6 mice. The European journal of neuroscience. vol 23. issue 4. 2006-05-09. PMID:16519673. |
pretreatment with deprenyl, a monoamine oxidase b inhibitor, or gbr-12909, a dopamine uptake inhibitor, almost completely attenuated both the increases in striatal lac/cr ratio and the subsequent loss of dopaminergic nerve terminals in mptp-treated mice. |
2006-05-09 |
2023-08-12 |
mouse |
| Krishnan Sriram, Joanna M Matheson, Stanley A Benkovic, Diane B Miller, Michael I Luster, James P O'Callagha. Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 6. 2006-05-08. PMID:16581975. |
mptp-induced expression of microglia-derived factors, tnf-alpha, mcp-1, and il-1alpha, preceded the degeneration of striatal dopaminergic nerve terminals and astrogliosis, as assessed by loss of striatal dopamine and th, and an increase in striatal gfap. |
2006-05-08 |
2023-08-12 |
mouse |
| Krishnan Sriram, Joanna M Matheson, Stanley A Benkovic, Diane B Miller, Michael I Luster, James P O'Callagha. Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 6. 2006-05-08. PMID:16581975. |
pharmacological neuroprotection with the dopamine reuptake inhibitor, nomifensine, abolished striatal dopaminergic neurotoxicity and associated microglial activation. |
2006-05-08 |
2023-08-12 |
mouse |
| Luoxiu Huang, Hans Maaswinkel, Lei L. Olfactoretinal centrifugal input modulates zebrafish retinal ganglion cell activity: a possible role for dopamine-mediated Ca2+ signalling pathways. The Journal of physiology. vol 569. issue Pt 3. 2006-05-04. PMID:16239263. |
olfactory stimulation with amino acids decreases dopamine release in the retina, thereby reducing dopaminergic inhibition of rgcs. |
2006-05-04 |
2023-08-12 |
zebrafish |
| M Leonetti, C Desvignes, I Bougault, J Souilhac, F Oury-Donat, R Steinber. 2-Chloro-N-[(S)-phenyl [(2S)-piperidin-2-yl] methyl]-3-trifluoromethyl benzamide, monohydrochloride, an inhibitor of the glycine transporter type 1, increases evoked-dopamine release in the rat nucleus accumbens in vivo via an enhanced glutamatergic neurotransmission. Neuroscience. vol 137. issue 2. 2006-05-03. PMID:16289893. |
since glutamate has been shown to play a role in the regulation of the dopaminergic system in dopamine-related disorders, such as schizophrenia, we investigated the possibility that ssr504734 may modify the basolateral amygdala-elicited stimulation of dopamine release in the nucleus accumbens via an augmentation of glutamate receptor-mediated neurotransmission. |
2006-05-03 |
2023-08-12 |
rat |