| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K R Kessler, N Hamscho, B Morales, C Menzel, F Barrero, F Vives, S Gispert, G Auburge. Dopaminergic function in a family with the PARK6 form of autosomal recessive Parkinson's syndrome. Journal of neural transmission (Vienna, Austria : 1996). vol 112. issue 10. 2006-08-18. PMID:15785866. |
in this family, we studied pre- and postsynaptic dopaminergic function using 123i-fp-cit- and 123i-iodobenzamide-spect to determine binding to the presynaptic dopamine transporter (dat) and postsynaptic d2 receptors respectively. |
2006-08-18 |
2023-08-12 |
Not clear |
| Mária Baranyi, Elisaveta Milusheva, E Sylvester Vizi, Beáta Sperlág. Chromatographic analysis of dopamine metabolism in a Parkinsonian model. Journal of chromatography. A. vol 1120. issue 1-2. 2006-08-18. PMID:16580006. |
reduced dopamine content and decreased extracellular level of [(3)h] and endogenous dopamine evoked by electrical stimulation indicated the injury of dopaminergic pathway. |
2006-08-18 |
2023-08-12 |
rat |
| Mária Baranyi, Elisaveta Milusheva, E Sylvester Vizi, Beáta Sperlág. Chromatographic analysis of dopamine metabolism in a Parkinsonian model. Journal of chromatography. A. vol 1120. issue 1-2. 2006-08-18. PMID:16580006. |
sensitivity of dopaminergic neurons were increased to oxidative stress with enhanced release of dopamine and formation of oxidized metabolite dopamine quinone (daq). |
2006-08-18 |
2023-08-12 |
rat |
| Jeffrey M Brown, Shawn Gouty, Varsha Iyer, John Rosenberger, Brian M Co. Differential protection against MPTP or methamphetamine toxicity in dopamine neurons by deletion of ppN/OFQ expression. Journal of neurochemistry. vol 98. issue 2. 2006-08-18. PMID:16749908. |
in contrast, meth administration preferentially damaged dopaminergic terminals in the cpu with little effect on dopamine neurons in the snpc, an effect not reversed by ppn/ofq gene deletion. |
2006-08-18 |
2023-08-12 |
mouse |
| M M Lewis, X Huang, D E Nichols, R B Mailma. D1 and functionally selective dopamine agonists as neuroprotective agents in Parkinson's disease. CNS & neurological disorders drug targets. vol 5. issue 3. 2006-08-18. PMID:16787233. |
the mainstream treatment has been dopaminergic replacement therapy aimed at symptomatic relief, with the gold standard drug being the dopamine precursor levodopa. |
2006-08-18 |
2023-08-12 |
Not clear |
| M M Lewis, X Huang, D E Nichols, R B Mailma. D1 and functionally selective dopamine agonists as neuroprotective agents in Parkinson's disease. CNS & neurological disorders drug targets. vol 5. issue 3. 2006-08-18. PMID:16787233. |
recently, a number of direct dopamine agonists that target the d(2) and d(3) dopamine receptors have been used as dopaminergic replacement strategies. |
2006-08-18 |
2023-08-12 |
Not clear |
| S A Stafford, J H Coot. Activation of D2-like receptors induces sympathetic climactic-like responses in male and female anaesthetised rats. British journal of pharmacology. vol 148. issue 4. 2006-08-16. PMID:16682961. |
in the present, study selective dopamine agonists and antagonists were used to investigate whether dopaminergic mechanisms influence the generation of this ejaculatory-related response. |
2006-08-16 |
2023-08-12 |
rat |
| Natsuko Kumamoto, Shinsuke Matsuzaki, Kiyoshi Inoue, Tsuyoshi Hattori, Shoko Shimizu, Ryota Hashimoto, Atsushi Yamatodani, Taiichi Katayama, Masaya Tohyam. Hyperactivation of midbrain dopaminergic system in schizophrenia could be attributed to the down-regulation of dysbindin. Biochemical and biophysical research communications. vol 345. issue 2. 2006-08-16. PMID:16701550. |
these data suggest that dysbindin might regulate the dopamine release of the dopaminergic system via modulation of the expression of snap25. |
2006-08-16 |
2023-08-12 |
mouse |
| Emilio C Campos, Michela Fresin. Medical treatment of amblyopia: present state and perspectives. Strabismus. vol 14. issue 2. 2006-08-16. PMID:16760111. |
the role of the dopaminergic system and particularly of dopamine in amblyopia are also discussed. |
2006-08-16 |
2023-08-12 |
Not clear |
| Shaji Theodore, Wayne A Cass, William F Marago. Involvement of cytokines in human immunodeficiency virus-1 protein Tat and methamphetamine interactions in the striatum. Experimental neurology. vol 199. issue 2. 2006-08-11. PMID:16510141. |
in previous studies, we demonstrated that the hiv-1 protein tat and ma interacted to cause enhanced loss of dopamine in the rat striatum via the destruction of dopaminergic terminals. |
2006-08-11 |
2023-08-12 |
mouse |
| S Delion, S Chalon, J Hérault, D Guilloteau, J C Besnard, G Duran. Chronic dietary alpha-linolenic acid deficiency alters dopaminergic and serotoninergic neurotransmission in rats. The Journal of nutrition. vol 124. issue 12. 2006-08-03. PMID:16856329. |
the results also showed some modification of dopaminergic neurotransmission specifically in the frontal cortex in the rats deficient in alpha-linolenic acid, with a significantly lower density of d2 receptors and a significantly lower concentration of endogenous dopamine than in control animals. |
2006-08-03 |
2023-08-12 |
rat |
| Vibhuti Srivastava, Panchami G Varma, Suman Prasad, Prachi Semwal, Vishwajit L Nimgaonkar, Bernard Lerer, Smita N Deshpande, Thelma B. Genetic susceptibility to tardive dyskinesia among schizophrenia subjects: IV. Role of dopaminergic pathway gene polymorphisms. Pharmacogenetics and genomics. vol 16. issue 2. 2006-07-31. PMID:16424823. |
we tested the possible association of 24 polymorphisms from six dopaminergic genes: namely, dopamine receptors d1, d2, d3, d4; the dopamine transporter (dat); and the catalyzing enzyme catechol-o-methyltransferase (comt), with td. |
2006-07-31 |
2023-08-12 |
human |
| J L Short, C Ledent, E Borrelli, J Drago, A J Lawrenc. Genetic interdependence of adenosine and dopamine receptors: evidence from receptor knockout mice. Neuroscience. vol 139. issue 2. 2006-07-31. PMID:16476524. |
this study was designed to investigate dopaminergic and purinergic systems in mice with ablations of individual dopamine or adenosine receptors. |
2006-07-31 |
2023-08-12 |
mouse |
| C-J Hong, H-C Liu, T-Y Liu, D-L Liao, S-J Tsa. Association studies of the adenosine A2a receptor (1976T > C) genetic polymorphism in Parkinson's disease and schizophrenia. Journal of neural transmission (Vienna, Austria : 1996). vol 112. issue 11. 2006-07-27. PMID:15719154. |
given the implications with respect to the pathogenesis of dopaminergic dysfunction in schizophrenia and parkinson's disease (pd), as well as the reciprocal antagonistic interactions between adenosine a2a receptor (a2aar) and the dopamine d2 receptors, a2aar may be a candidate gene conferring susceptibility to pd or schizophrenia. |
2006-07-27 |
2023-08-12 |
Not clear |
| María Nieto, Francisco J Gil-Bea, Esther Dalfó, Mar Cuadrado, Felipe Cabodevilla, Belén Sánchez, Silvia Catena, Teresa Sesma, Elena Ribé, Isidro Ferrer, María J Ramírez, Teresa Gómez-Isl. Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice. Neurobiology of aging. vol 27. issue 6. 2006-07-26. PMID:16006012. |
while sensitivity to chronic treatment with rotenone was not enhanced in the tg5093 line, chronic treatment with 80 or 150 mg/kg mptp resulted in increased deterioration of the nigrostriatal dopaminergic system as assessed by quantitation of nigral tyrosine hydroxylase (th) positive neurons and striatal dopamine (da) levels in tg5093 mice when compared to non-transgenic littermate controls. |
2006-07-26 |
2023-08-12 |
mouse |
| Taku Inoue, Atsushi Matsubara, Shin-ichiro Maruya, Yohei Yamamoto, Atsushi Namba, Akira Sasaki, Hideichi Shinkaw. Localization of dopamine receptor subtypes in the rat spiral ganglion. Neuroscience letters. vol 399. issue 3. 2006-07-26. PMID:16490310. |
although dopaminergic neurons are thought to exist in the lateral olivocochlear efferent system and modulate the afferent nerve activity, the distribution of dopamine (da) receptor subtypes is still obscure. |
2006-07-26 |
2023-08-12 |
rat |
| David McLaughlin, Emmanouella Tsirimonaki, George Vallianatos, Nikolaos Sakellaridis, Theofanis Chatzistamatiou, Catherine Stavropoulos-Gioka, Aspasia Tsezou, Ioannis Messinis, Dimitra Mangour. Stable expression of a neuronal dopaminergic progenitor phenotype in cell lines derived from human amniotic fluid cells. Journal of neuroscience research. vol 83. issue 7. 2006-07-25. PMID:16555279. |
further analysis showed strong expression of en-1, c-ret, ptx3, and nurr1 essential for induction and survival of midbrain dopaminergic neurons, th, aadc, and vmat2 components of dopamine synthesis and secretion, and syntaxin1a and snap-25 necessary for neurotransmitter exocytosis. |
2006-07-25 |
2023-08-12 |
human |
| Monica Mameli-Engvall, Alexis Evrard, Stéphanie Pons, Uwe Maskos, Torgny H Svensson, Jean-Pierre Changeux, Philippe Faur. Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors. Neuron. vol 50. issue 6. 2006-07-25. PMID:16772172. |
nicotine elicits dopamine release by stimulating nicotinic acetylcholine receptors (nachrs) on dopaminergic neurons. |
2006-07-25 |
2023-08-12 |
mouse |
| Jackalina M Van Kampen, Christopher B Eckma. Dopamine D3 receptor agonist delivery to a model of Parkinson's disease restores the nigrostriatal pathway and improves locomotor behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 27. 2006-07-25. PMID:16822985. |
the small molecule neurotransmitter dopamine has been shown to regulate cell cycle in developing and adult brain, and the d3 receptor is known to play an important role in dopaminergic development. |
2006-07-25 |
2023-08-12 |
rat |
| Khaled Radad, Gabriele Gille, Wolf-Dieter Rausc. Short review on dopamine agonists: insight into clinical and research studies relevant to Parkinson's disease. Pharmacological reports : PR. vol 57. issue 6. 2006-07-21. PMID:16382188. |
parkinson's disease (pd) is a chronic and progressive neurological disorder characterized by selective degeneration of dopaminergic neurons (daergic) in the substantia nigra pars compacta (snpc) and subsequent decrease in dopamine (da) levels in the striatum. |
2006-07-21 |
2023-08-12 |
Not clear |