| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jun Wang, Sharon K Michelhaugh, Michael J Banno. Valproate robustly increases Sp transcription factor-mediated expression of the dopamine transporter gene within dopamine cells. The European journal of neuroscience. vol 25. issue 7. 2007-06-21. PMID:17439486. |
utilizing a human dopaminergic cell line and rat midbrain dopamine (da) neurons in organotypic culture, we found that valproate increased endogenous dat gene expression in a concentration- and time-dependent manner. |
2007-06-21 |
2023-08-12 |
human |
| Diane T Stephenson, Mary Abigail Childs, Qiu Li, Santos Carvajal-Gonzalez, Alan Opsahl, Mark Tengowski, Martin D Meglasson, Kalpana Merchant, Marina E Embor. Differential loss of presynaptic dopaminergic markers in Parkinsonian monkeys. Cell transplantation. vol 16. issue 3. 2007-06-21. PMID:17503735. |
tyrosine hydroxylase (th), dopamine transporter (dat), vesicular monoamine transporter 2 (vmat2), and amino acid decarboxylase (aadc) are widely used markers of dopaminergic neurons and terminals. |
2007-06-21 |
2023-08-12 |
monkey |
| N A Krupina, N N Zolotov, N G Bogdanova, I N Orlova, N N Khlebnikova, G N Kryzhanovski. Activities of prolyl endopeptidase and dipeptidyl peptidase IV in brain structures of rats with dopamine deficiency-dependent MPTP-induced depressive syndrome. Bulletin of experimental biology and medicine. vol 142. issue 5. 2007-06-19. PMID:17415460. |
our results indicate that proline-specific peptidases in the target structures of the brain dopaminergic system are involved in the pathogenesis of dopamine deficiency-dependent depressive states. |
2007-06-19 |
2023-08-12 |
rat |
| Agnès Maurel, Odile Spreux-Varoquaux, Francesco Amenta, Seyed Khosrow Tayebati, Daniele Tomassoni, Marie-Hélène Seguelas, Angelo Parini, Nathalie Pizzina. Vesicular monoamine transporter 1 mediates dopamine secretion in rat proximal tubular cells. American journal of physiology. Renal physiology. vol 292. issue 5. 2007-06-18. PMID:17244889. |
although the renal dopaminergic system has been extensively investigated in both physiological and pathological situations, the mechanisms whereby dopamine is stored and secreted by proximal tubule cells remain obscure. |
2007-06-18 |
2023-08-12 |
rat |
| Shoko Hirano, Shigeo Miyata, Kenji Onodera, Junzo Kame. Involvement of dopamine D1 receptors and alpha1-adrenoceptors in the antidepressant-like effect of chlorpheniramine in the mouse tail suspension test. European journal of pharmacology. vol 562. issue 1-2. 2007-06-13. PMID:17328889. |
in this study, we examined the involvement of dopaminergic (dopamine d(1) and dopamine d(2) receptors), noradrenergic (alpha(1)- and beta-adrenoceptors) and serotonergic (5-ht(1a) and 5-ht(2) receptors) receptors in the antidepressant-like effect of chlorpheniramine in the mouse tail suspension test. |
2007-06-13 |
2023-08-12 |
mouse |
| Beatriz Abril, Bertrand Carlander, Jacques Touchon, Yves Dauvillier. Restless legs syndrome in narcolepsy: a side effect of sodium oxybate? Sleep medicine. vol 8. issue 2. 2007-06-08. PMID:17275405. |
as dopaminergic transmission is clearly involved in the pathophysiology of restless legs syndrome (rls), and ghb reduces dopamine release, one may hypothesize that rls may occur in narcolepsy in the presence of ghb. |
2007-06-08 |
2023-08-12 |
human |
| Juliana Yacubian, Tobias Sommer, Katrin Schroeder, Jan Gläscher, Raffael Kalisch, Boris Leuenberger, Dieter F Braus, Christian Büche. Gene-gene interaction associated with neural reward sensitivity. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 19. 2007-06-07. PMID:17483451. |
reward processing depends on dopaminergic neurotransmission and is modulated by factors affecting dopamine (da) reuptake and degradation. |
2007-06-07 |
2023-08-12 |
human |
| Melvin C Gitlin, Bradley K Taylor, Philip L Kalarickal, Eric D Lonset. Does dysregulation of catechol-O-methyltransferase predispose to opioid-induced hallucinations? A report of a patient with microdeletion of chromosome 22 and opioid-associated hallucinations. Pain medicine (Malden, Mass.). vol 8. issue 1. 2007-06-06. PMID:17244108. |
overactivity of the dopaminergic system has been postulated to cause schizophrenia in this population, and here we speculate that dysregulation of dopamine metabolism may have predisposed our patient to an increased risk of opioid-induced hallucinations. |
2007-06-06 |
2023-08-12 |
Not clear |
| Bernard L Schneider, Corey R Seehus, Elizabeth E Capowski, Patrick Aebischer, Su-Chun Zhang, Clive N Svendse. Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation. Human molecular genetics. vol 16. issue 6. 2007-06-06. PMID:17309880. |
consistent with the selective vulnerability of ventral midbrain dopaminergic neurons, alpha-synuclein cytotoxicity appeared most pronounced following fgf8/shh specification and was decreased by inhibition of dopamine synthesis. |
2007-06-06 |
2023-08-12 |
human |
| Marc Welter, Daniela Vallone, Tarek A Samad, Hamid Meziane, Alessandro Usiello, Emiliana Borrell. Absence of dopamine D2 receptors unmasks an inhibitory control over the brain circuitries activated by cocaine. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 16. 2007-06-06. PMID:17426149. |
cocaine elicits its effects primarily by blocking the activity of the dopamine (da) transporter, leading to elevated levels of extracellular da in areas receiving dopaminergic innervation, with the consequent activation of da receptors. |
2007-06-06 |
2023-08-12 |
mouse |
| Jelena Mijatovic, Mikko Airavaara, Anu Planken, Petri Auvinen, Atso Raasmaja, T Petteri Piepponen, Frank Costantini, Liisa Ahtee, Mart Saarm. Constitutive Ret activity in knock-in multiple endocrine neoplasia type B mice induces profound elevation of brain dopamine concentration via enhanced synthesis and increases the number of TH-positive cells in the substantia nigra. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 18. 2007-06-06. PMID:17475787. |
we used knock-in men2b mice with the ret-men2b mutation to study the effects of constitutive ret activity on the brain dopaminergic system and found robustly increased concentrations of dopamine (da) and its metabolites in the striatum, cortex, and hypothalamus. |
2007-06-06 |
2023-08-12 |
mouse |
| Valerie M Tatard, Gianluca D'Ippolito, Sylma Diabira, Alexander Valeyev, John Hackman, Micheline McCarthy, Thomas Bouckenooghe, Philippe Menei, Claudia N Montero-Menei, Paul C Schille. Neurotrophin-directed differentiation of human adult marrow stromal cells to dopaminergic-like neurons. Bone. vol 40. issue 2. 2007-06-04. PMID:17085092. |
supplementing the aforementioned multi-step process with sonic hedgehog, fibroblast growth factor 8, and retinoic acid increased the expression of molecules involved in dopaminergic differentiation and of tyrosine hydroxylase, the rate limiting enzyme of dopamine synthesis. |
2007-06-04 |
2023-08-12 |
human |
| David A Price, William A Owens, Georgianna G Gould, Alan Frazer, James L Roberts, Lynette C Daws, Andrea Giuffrid. CB1-independent inhibition of dopamine transporter activity by cannabinoids in mouse dorsal striatum. Journal of neurochemistry. vol 101. issue 2. 2007-06-01. PMID:17250681. |
in this study, we used in vitro and in vivo techniques to investigate whether cannabinoid agonists and antagonist could affect dopaminergic transmission in the striatum by acting at the dopamine transporter. |
2007-06-01 |
2023-08-12 |
mouse |
| b' Janusz Borycz, M F\\xc3\\xa1tima Pereira, Alessia Melani, Ricardo J Rodrigues, Attila K\\xc3\\xb6falvi, Leigh Panlilio, Felicita Pedata, Steven R Goldberg, Rodrigo A Cunha, Sergi Ferr\\xc3\\xa. Differential glutamate-dependent and glutamate-independent adenosine A1 receptor-mediated modulation of dopamine release in different striatal compartments. Journal of neurochemistry. vol 101. issue 2. 2007-06-01. PMID:17254024.' |
furthermore, using immunocytochemical and functional studies in rat striatal synaptosomes, we demonstrate that a fraction of striatal dopaminergic terminals contains adenosine a(1) receptors, which directly inhibit dopamine release independently of glutamatergic transmission. |
2007-06-01 |
2023-08-12 |
rat |
| Patrick P Michel, Daniel Alvarez-Fischer, Serge Guerreiro, Audrey Hild, Andreas Hartmann, Etienne C Hirsc. Role of activity-dependent mechanisms in the control of dopaminergic neuron survival. Journal of neurochemistry. vol 101. issue 2. 2007-06-01. PMID:17402966. |
these electrophysiological features allow dopaminergic neurons to optimize the release of dopamine in their terminal fields. |
2007-06-01 |
2023-08-12 |
Not clear |
| J Parga, J Rodriguez-Pallares, A Muñoz, M J Guerra, J L Labandeira-Garci. Serotonin decreases generation of dopaminergic neurons from mesencephalic precursors via serotonin type 7 and type 4 receptors. Developmental neurobiology. vol 67. issue 1. 2007-06-01. PMID:17443768. |
treatment with the 5-ht(1b/1d) antagonist gr 127935, the 5-ht(2) antagonist ritanserin, the 5-ht transporter inhibitor fluoxetine, the dopamine and norepinephrine transport inhibitor gbr 12935, or with both inhibitors together, or 5-ht(4) or 5-ht(7) receptor agonists induced significant decreases in generation of dopaminergic cells. |
2007-06-01 |
2023-08-12 |
rat |
| Danhui Zhang, Arthi Kanthasamy, Yongjie Yang, Vellareddy Anantharam, Anumantha Kanthasam. Protein kinase C delta negatively regulates tyrosine hydroxylase activity and dopamine synthesis by enhancing protein phosphatase-2A activity in dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 20. 2007-05-31. PMID:17507557. |
protein kinase c delta negatively regulates tyrosine hydroxylase activity and dopamine synthesis by enhancing protein phosphatase-2a activity in dopaminergic neurons. |
2007-05-31 |
2023-08-12 |
mouse |
| Sandra G Vincent, Andrea E Waddell, Marc G Caron, Julia K L Walker, John T Fishe. A murine model of hyperdopaminergic state displays altered respiratory control. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 21. issue 7. 2007-05-30. PMID:17255472. |
we conclude that loss of the dat protein in this murine model of altered dopaminergic neurotransmission results in a significant respiratory and thermal phenotype that has possible implications for understanding of conditions associated with altered dopamine regulation. |
2007-05-30 |
2023-08-12 |
mouse |
| Norman Wolkove, Osama Elkholy, Marc Baltzan, Mark Palaye. Sleep and aging: 2. Management of sleep disorders in older people. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. vol 176. issue 10. 2007-05-30. PMID:17485699. |
restless legs syndrome and periodic leg-movement disorder are treated with benzodiazepines or dopaminergic agents such as levodopa-carbidopa and, more recently, newer dopamine agonists. |
2007-05-30 |
2023-08-12 |
Not clear |
| J D Foster, M A Cervinski, B K Gorentla, R A Vaugha. Regulation of the dopamine transporter by phosphorylation. Handbook of experimental pharmacology. issue 175. 2007-05-23. PMID:16722237. |
the dopamine transporter (dat) is a neuronal phosphoprotein and target for psychoactive drugs that plays a critical role in terminating dopaminergic transmission by reuptake of dopamine from the synaptic space. |
2007-05-23 |
2023-08-12 |
Not clear |