| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hiroo Yamaguchi, Jie She. Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice. Molecular neurodegeneration. vol 2. 2007-07-30. PMID:17535435. |
we found that dj-1-/- mice at the age of 24-27 months have normal numbers of dopaminergic neurons in the substantia nigra and normal levels of dopamine and its major metabolites in the striatum. |
2007-07-30 |
2023-08-12 |
mouse |
| Dayong Wang, Yukihiro Noda, Yuan Zhou, Akihiro Mouri, Hiroyuki Mizoguchi, Atsumi Nitta, Weiduo Chen, Toshitaka Nabeshim. The allosteric potentiation of nicotinic acetylcholine receptors by galantamine ameliorates the cognitive dysfunction in beta amyloid25-35 i.c.v.-injected mice: involvement of dopaminergic systems. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 6. 2007-07-27. PMID:17133263. |
the improving-effects of galantamine on the abeta(25-35)-induced cognitive impairment may be mediated through the activation of, at least in part, dopaminergic systems, and the enhancement of dopamine release may be one of multiple mechanisms underlying the therapeutic benefit of galantamine. |
2007-07-27 |
2023-08-12 |
mouse |
| Nimish Sidhpura, Peter Redfern, Susan Wonnacot. Comparison of the effects of bupropion on nicotinic receptor-evoked [(3)H]dopamine release from rat striatal synaptosomes and slices. European journal of pharmacology. vol 567. issue 1-2. 2007-07-27. PMID:17477919. |
tobacco smoking is a nicotine addiction, mediated in part by the ability of nicotine to elicit dopamine release, as a result of the stimulation of nicotinic acetylcholine receptors associated with dopaminergic pathways. |
2007-07-27 |
2023-08-12 |
rat |
| Han-Qing Chen, Zheng-Yu Jin, Guan-Hong L. Biochanin A protects dopaminergic neurons against lipopolysaccharide-induced damage through inhibition of microglia activation and proinflammatory factors generation. Neuroscience letters. vol 417. issue 2. 2007-07-25. PMID:17399896. |
in this study, we reported that biochanin a, one of the predominant isoflavones in trifolium pratense, attenuated lipopolysaccharide (lps)-induced decrease in dopamine uptake and the number of dopaminergic neurons in a dose-dependent manner in rat mesencephalic neuron-glia cultures. |
2007-07-25 |
2023-08-12 |
rat |
| Yael Ni. Cost, benefit, tonic, phasic: what do response rates tell us about dopamine and motivation? Annals of the New York Academy of Sciences. vol 1104. 2007-07-25. PMID:17416928. |
we hypothesize that this critical quantity is conveyed by tonic levels of dopamine, explaining why dopaminergic manipulations exert a global affect on response rates. |
2007-07-25 |
2023-08-12 |
Not clear |
| Marko Schirmer, Alina Lessenich, Sven Lindemann, Wolfgang Lösche. Marked differences in response to dopamine receptor antagonism in two rat mutants, ci2 and ci3, with lateralized rotational behavior. Behavioural brain research. vol 180. issue 2. 2007-07-24. PMID:17442411. |
both mutants show abnormal lateralities in striatal dopamine and in the density of dopaminergic neurons in substantia nigra or ventral tegmental area, which may be involved in the behavioral phenotype of these rats. |
2007-07-24 |
2023-08-12 |
rat |
| Janice H Silva, Renato S Gomez, Paulo H C Diniz, Marcus V Gomez, Cristina Guatimosi. The effect of sevoflurane on the release of [3H]dopamine from rat brain cortical slices. Brain research bulletin. vol 72. issue 4-6. 2007-07-24. PMID:17452291. |
dopamine is a neurotransmitter that exerts major control on important brain functions and some lines of studies suggest that dopaminergic neurotransmission may be a potential target for volatile anesthetics. |
2007-07-24 |
2023-08-12 |
rat |
| Claudia Trenkwalder, Heike Benes, Ludger Grote, Svenja Happe, Birgit Högl, Johannes Mathis, Gerda M Saletu-Zyhlarz, Ralf Kohne. Cabergoline compared to levodopa in the treatment of patients with severe restless legs syndrome: results from a multi-center, randomized, active controlled trial. Movement disorders : official journal of the Movement Disorder Society. vol 22. issue 5. 2007-07-23. PMID:17274039. |
we report the first large-scale double-blind, randomly assigned study to compare two active dopaminergic therapies for restless legs syndrome (rls), the dopamine agonist cabergoline (cab) and levodopa/benserazide (levodopa). |
2007-07-23 |
2023-08-12 |
Not clear |
| Victor C Huber, Tapan Mondal, Stewart A Factor, Richard F Seegal, David A Lawrenc. Serum antibodies from Parkinson's disease patients react with neuronal membrane proteins from a mouse dopaminergic cell line and affect its dopamine expression. Journal of neuroinflammation. vol 3. 2007-07-20. PMID:16426448. |
serum antibodies from parkinson's disease patients react with neuronal membrane proteins from a mouse dopaminergic cell line and affect its dopamine expression. |
2007-07-20 |
2023-08-12 |
mouse |
| Raphael E Szawka, Gisele V Rodovalho, Cleyde V V Helena, Celso R Franci, Janete A Anselmo-Franc. Prolactin secretory surge during estrus coincides with increased dopamine activity in the hypothalamus and preoptic area and is not altered by ovariectomy on proestrus. Brain research bulletin. vol 73. issue 1-3. 2007-07-20. PMID:17499646. |
considering that dopamine is the main inhibitor of prl release and that prl auto-regulates its secretion through a short-loop feedback mechanism, our present results suggest that prl may suppress its own secretion during the estrus surge through the activation of the dopaminergic neurons in the mbh and mpoa. |
2007-07-20 |
2023-08-12 |
rat |
| Shih-Jen Tsa. Attention-deficit hyperactivity disorder may be associated with decreased central brain-derived neurotrophic factor activity: clinical and therapeutic implications. Medical hypotheses. vol 68. issue 4. 2007-07-18. PMID:16919891. |
drawing on findings from studies into the drugs for adhd relating to central bdnf expression, hyperactivity in bdnf knockout mice, bdnf effects in midbrain dopaminergic function and the close association between bdnf and the dopamine transporter (an important molecule for adhd pathogenesis), it is proposed here that decreased central bdnf, particularly in the midbrain region, may play an important role in the pathogenesis adhd. |
2007-07-18 |
2023-08-12 |
mouse |
| Chi-Un Pae, Chul Lee, In-Ho Pai. Therapeutic possibilities of cysteamine in the treatment of schizophrenia. Medical hypotheses. vol 69. issue 1. 2007-07-18. PMID:17166669. |
cysteamine can also stimulate the release of cortical dopamine, which is interesting in that decreased dopaminergic function in the cerebral cortex has been repeatedly demonstrated in patients with schizophrenia and associated with prominent depressive and negative symptoms. |
2007-07-18 |
2023-08-12 |
Not clear |
| Taiki Takahash. Hyperbolic discounting may be reduced to electrical coupling in dopaminergic neural circuits. Medical hypotheses. vol 69. issue 1. 2007-07-18. PMID:17196757. |
with respect to neuronal changes induced by drugs of abuse, recent studies have revealed that gap junction proteins (e.g., connexin 36) in dopamine neurons are increased by an self-administration of dopaminergic drugs such as cocaine and amphetamine. |
2007-07-18 |
2023-08-12 |
human |
| Taiki Takahash. Hyperbolic discounting may be reduced to electrical coupling in dopaminergic neural circuits. Medical hypotheses. vol 69. issue 1. 2007-07-18. PMID:17196757. |
based on these current findings, we hypothesized that hyperbolic discounting may be reduced to biophysical characteristics of dopamine neural circuits, that is, electrical coupling between time-encoding dopaminergic neurons via gap junctions. |
2007-07-18 |
2023-08-12 |
human |
| Yusaku Nakabeppu, Daisuke Tsuchimoto, Hiroo Yamaguchi, Kunihiko Sakum. Oxidative damage in nucleic acids and Parkinson's disease. Journal of neuroscience research. vol 85. issue 5. 2007-07-18. PMID:17279544. |
we have shown a significant increase in 8-oxog in mitochondrial dna as well as an elevated expression of mth1, ogg1, and mutyh in nigrostriatal dopaminergic neurons of pd patients, suggesting that the buildup of these lesions may cause dopamine neuron loss. |
2007-07-18 |
2023-08-12 |
mouse |
| Marco Bisaglia, Stefano Mammi, Luigi Bubacc. Kinetic and structural analysis of the early oxidation products of dopamine: analysis of the interactions with alpha-synuclein. The Journal of biological chemistry. vol 282. issue 21. 2007-07-18. PMID:17395592. |
nigral dopaminergic neurons are particularly exposed to oxidative stress because a pathological accumulation of cytosolic dopamine gives rise to various toxic molecules, including free radicals and reactive quinones. |
2007-07-18 |
2023-08-12 |
Not clear |
| Raül Andero, Meritxell Torras-Garcia, María Fernanda Quiroz-Padilla, David Costa-Miserachs, Margalida Coll-Andre. Electrical stimulation of the pedunculopontine tegmental nucleus in freely moving awake rats: time- and site-specific effects on two-way active avoidance conditioning. Neurobiology of learning and memory. vol 87. issue 4. 2007-07-16. PMID:17169591. |
stimulation of the pptg in anesthetized animals increases cortical arousal, cortical acetylcholine release, bursting activity of mesopontine dopaminergic cells, and striatal dopamine release. |
2007-07-16 |
2023-08-12 |
rat |
| I G Sil'ki. [Role of dopamine-dependent negative feedback in the hippocampal--basal ganglia--thalamo---hippocampal loop in response decrement]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 93. issue 3. 2007-07-16. PMID:17598465. |
however, increase in dopamine level and activation of d2 receptors on the striatopallidal cell, while promoting depression of hippocampal inputs, prevents disinhibition of dopaminergic cells, and their reactions start their decrement. |
2007-07-16 |
2023-08-12 |
Not clear |
| Trent J Volz, Glen R Hanson, Annette E Fleckenstei. The role of the plasmalemmal dopamine and vesicular monoamine transporters in methamphetamine-induced dopaminergic deficits. Journal of neurochemistry. vol 101. issue 4. 2007-07-12. PMID:17250674. |
the role of the plasmalemmal dopamine and vesicular monoamine transporters in methamphetamine-induced dopaminergic deficits. |
2007-07-12 |
2023-08-12 |
Not clear |
| Trent J Volz, Glen R Hanson, Annette E Fleckenstei. The role of the plasmalemmal dopamine and vesicular monoamine transporters in methamphetamine-induced dopaminergic deficits. Journal of neurochemistry. vol 101. issue 4. 2007-07-12. PMID:17250674. |
this review thus focuses on the effects of amph and meth on the plasmalemmal dopamine transporter and the vesicular monoamine transporter-2 in animal models with a particular emphasis on how these effects, which may vary for the different stereoisomers, contribute to persistent dopaminergic deficits. |
2007-07-12 |
2023-08-12 |
Not clear |