| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Kabbaj, C Isgo. Effects of chronic environmental and social stimuli during adolescence on mesolimbic dopaminergic circuitry markers. Neuroscience letters. vol 422. issue 1. 2007-09-26. PMID:17590508. |
no change has been detected in any other dopaminergic markers [d2r, d3r, tyrosine hydroxylase (th) or dopamine transporter (dat) mrnas]. |
2007-09-26 |
2023-08-12 |
rat |
| J D Newcomb, M Janowski, T Zigova, S Saporta, M P McGrogan, P R Sanberg, A E Willin. A comparison of dopaminergic cells from the human NTera2/D1 cell line transplanted into the hemiparkinsonian rat. Life sciences. vol 81. issue 6. 2007-09-26. PMID:17662308. |
human nt cells derived from the ntera2/d1 cell line express a dopaminergic phenotype making them an attractive vehicle to supply dopamine to the depleted striatum of the parkinsonian patient. |
2007-09-26 |
2023-08-12 |
human |
| Mi Kyung Lee, Soon Ja Kang, Mortimer Poncz, Ki-Joon Song, Kwang Sook Par. Resveratrol protects SH-SY5Y neuroblastoma cells from apoptosis induced by dopamine. Experimental & molecular medicine. vol 39. issue 3. 2007-09-24. PMID:17603292. |
dopamine (da) is an oxidant that may contribute to the degeneration of dopaminergic neurons. |
2007-09-24 |
2023-08-12 |
Not clear |
| Kiyomi Y Araki, John R Sims, Pradeep G Bhid. Dopamine receptor mRNA and protein expression in the mouse corpus striatum and cerebral cortex during pre- and postnatal development. Brain research. vol 1156. 2007-09-21. PMID:17509542. |
the outcome of dopaminergic signaling and effectiveness of dopaminergic drugs depend on the relative preponderance of each of the five dopamine receptors in a given brain region. |
2007-09-21 |
2023-08-12 |
mouse |
| J Myslivecek, J Cendelín, I Korelusová, M Kunová, V Markvartová, F Voze. Changes of dopamine receptors in mice with olivocerebellar degeneration. Prague medical report. vol 108. issue 1. 2007-09-21. PMID:17682727. |
in order to elucidate the role of dopaminergic receptor system in coping with mutation in delta2 glutamate receptor the behavioral effect (spatial learning) of d1 dopamine receptor activation and inhibition and changes in d1-like and d2-like dopamine receptors in striatum, hippocampus and cerebellum in c57bi/7 and c3h lurcher mutants and wild type mice were studied. |
2007-09-21 |
2023-08-12 |
mouse |
| Alice Guyon, Jean-Louis Naho. Multiple actions of the chemokine stromal cell-derived factor-1alpha on neuronal activity. Journal of molecular endocrinology. vol 38. issue 3. 2007-09-18. PMID:17339399. |
in various neuronal populations (ca1 neurons of the hippocampus, granular and purkinje cells of the cerebellum, melanin-concentrating hormone neurons of the lateral hypothalamus, vasopressinergic neurons of the supraoptic and the paraventricular nucleus of the hypothalamus, and dopaminergic neurons of the substantia nigra), sdf-1alpha can modulate the activity of neurons by multiple regulatory pathways including and often combining: (i) modulation of voltage-dependent channels (sodium, potassium, and calcium), (ii) activation of the g-protein-activated inward rectifier potassium current, and (iii) increase in neurotransmitter release (gamma-amino butyric acid (gaba), glutamate, and dopamine), often through ca-dependent mechanisms. |
2007-09-18 |
2023-08-12 |
Not clear |
| Ramesh C Juyal, Mitashree Das, Sohan Punia, Madhuri Behari, Geetika Nainwal, Sumit Singh, Pazhayannur V Swaminath, Shyla T Govindappa, Sachi Jayaram, Uday B Muthane, B K Thelm. Genetic susceptibility to Parkinson's disease among South and North Indians: I. Role of polymorphisms in dopamine receptor and transporter genes and association of DRD4 120-bp duplication marker. Neurogenetics. vol 7. issue 4. 2007-09-12. PMID:16816977. |
the depletion of dopamine levels in the brain due to degeneration of dopaminergic neurons of substantia nigra pars compacta is a hallmark of parkinson's disease (pd). |
2007-09-12 |
2023-08-12 |
Not clear |
| Jacek Wójcikowski, Krystyna Gołembiowska, Władysława Anna Danie. The regulation of liver cytochrome p450 by the brain dopaminergic system. Current drug metabolism. vol 8. issue 6. 2007-09-11. PMID:17691922. |
by dopamine receptor-blocking neuroleptics) may cause changes in cyp activity of physiological, pharmacological and toxicological significance, since cyp isoforms that are regulated by the dopaminergic system catalyze the metabolism of endogenous substances (e.g. |
2007-09-11 |
2023-08-12 |
rat |
| R Pollice, E Di Giovambattista, A Tomassini, A Di Pucchio, D Ussorio, R Roncone, M Casacchi. [Antipsychotic-induced symptomatic hyperprolactinemia: clinical consequences and therapeutic strategies]. La Clinica terapeutica. vol 158. issue 2. 2007-09-07. PMID:17566521. |
drugs which act on the dopaminergic system and/or on the dopamine hypophysis receptors, could increase the prolactin levels. |
2007-09-07 |
2023-08-12 |
human |
| A W Michell, G K Tofaris, H Gossage, P Tyers, M G Spillantini, R A Barke. The effect of truncated human alpha-synuclein (1-120) on dopaminergic cells in a transgenic mouse model of Parkinson's disease. Cell transplantation. vol 16. issue 5. 2007-09-07. PMID:17708336. |
however, in vivo the substantia nigra/ventral tegmentum dopaminergic cell counts were not reduced in transgenics, although these mice are known to have reduced striatal dopamine. |
2007-09-07 |
2023-08-12 |
mouse |
| David Weinshenker, Jason P Schroede. There and back again: a tale of norepinephrine and drug addiction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 7. 2007-08-31. PMID:17164822. |
however, reward experiments from the mid-1970s that could distinguish between the noradrenergic and dopaminergic systems resulted in the prevailing view that dopamine (da) was the primary 'reward transmitter' (a belief holding some sway still today), thereby pushing ne into the background. |
2007-08-31 |
2023-08-12 |
mouse |
| Marc Turiault, Sébastien Parnaudeau, Aude Milet, Rosanna Parlato, Jean-Denis Rouzeau, Monique Lazar, François Tronch. Analysis of dopamine transporter gene expression pattern -- generation of DAT-iCre transgenic mice. The FEBS journal. vol 274. issue 14. 2007-08-30. PMID:17565601. |
the dopamine transporter is an essential component of the dopaminergic synapse. |
2007-08-30 |
2023-08-12 |
mouse |
| Marc Turiault, Sébastien Parnaudeau, Aude Milet, Rosanna Parlato, Jean-Denis Rouzeau, Monique Lazar, François Tronch. Analysis of dopamine transporter gene expression pattern -- generation of DAT-iCre transgenic mice. The FEBS journal. vol 274. issue 14. 2007-08-30. PMID:17565601. |
we generated a transgenic mouse line expressing the cre recombinase under the control of the regulatory elements of the dopamine transporter gene, for investigations of gene function in dopaminergic neurons. |
2007-08-30 |
2023-08-12 |
mouse |
| M Airavaara, H Tuomainen, T P Piepponen, M Saarma, L Ahte. Effects of repeated morphine on locomotion, place preference and dopamine in heterozygous glial cell line-derived neurotrophic factor knockout mice. Genes, brain, and behavior. vol 6. issue 3. 2007-08-29. PMID:16879618. |
to study the effects of reduced gdnf on dopaminergic behaviour related to addiction, we compared the effects of morphine on locomotor activity, conditioned place preference (cpp) and extracellular accumbal dopamine in heterozygous gdnf knockout mice (gdnf+/-) with those in their wild-type (wt) littermates. |
2007-08-29 |
2023-08-12 |
mouse |
| James M Swanso. Role of executive function in ADHD. The Journal of clinical psychiatry. vol 64 Suppl 14. 2007-08-27. PMID:14658934. |
stimulants primarily have dopaminergic and noradrenergic mechanisms of action, with blockade at the dopamine transporter reducing reuptake, resulting in an increase in these neurotransmitters at the synapse. |
2007-08-27 |
2023-08-12 |
Not clear |
| James M Swanso. Role of executive function in ADHD. The Journal of clinical psychiatry. vol 64 Suppl 14. 2007-08-27. PMID:14658934. |
although modafinil exhibits a small degree of dopaminergic action by blocking the dopamine transporter, the major effect of modafinil may be attributable to neuronal activity in the hypothalamus, particularly pertaining to the recently discovered peptides hypocretin 1 and 2 (also known as orexin a and b). |
2007-08-27 |
2023-08-12 |
Not clear |
| Patrick B Wood, Petra Schweinhardt, Erik Jaeger, Alain Dagher, Helene Hakyemez, Eugenii A Rabiner, M Catherine Bushnell, Boris A Chiz. Fibromyalgia patients show an abnormal dopamine response to pain. The European journal of neuroscience. vol 25. issue 12. 2007-08-24. PMID:17610577. |
because dopamine is implicated in both pain modulation and affective processing, we hypothesized that fibromyalgia may involve a disturbance of dopaminergic neurotransmission. |
2007-08-24 |
2023-08-12 |
human |
| James M Swanson, Marcel Kinsbourne, Joel Nigg, Bruce Lanphear, Gerry A Stefanatos, Nora Volkow, Eric Taylor, B J Casey, F Xavier Castellanos, Pathik D Wadhw. Etiologic subtypes of attention-deficit/hyperactivity disorder: brain imaging, molecular genetic and environmental factors and the dopamine hypothesis. Neuropsychology review. vol 17. issue 1. 2007-08-21. PMID:17318414. |
first, we consider evidence of the presence of dopamine deficits based on the recent literature that (1) confirms abnormalities in dopamine-modulated frontal-striatal circuits, reflected by size (smaller-than-average components) and function (hypoactivation); (2) clarifies the agonist effects of stimulant medication on dopaminergic mechanisms at the synaptic and circuit level of analysis; and (3) challenges the most-widely accepted adhd-related neural abnormality in the dopamine system (higher-than-normal dopamine transporter [dat] density). |
2007-08-21 |
2023-08-12 |
Not clear |
| Soojin Ryu, Julia Mahler, Dario Acampora, Jochen Holzschuh, Simone Erhardt, Daniela Omodei, Antonio Simeone, Wolfgang Drieve. Orthopedia homeodomain protein is essential for diencephalic dopaminergic neuron development. Current biology : CB. vol 17. issue 10. 2007-08-17. PMID:17481897. |
in fish, overexpression of otp can induce ectopic tyrosine hydroxylase and dopamine transporter expression, indicating that otp can specify aspects of dopaminergic identity. |
2007-08-17 |
2023-08-12 |
mouse |
| Gonzalo Arboleda, Tze-Jen Huang, Catherine Waters, Alex Verkhratsky, Paul Fernyhough, Rosemary M Gibso. Insulin-like growth factor-1-dependent maintenance of neuronal metabolism through the phosphatidylinositol 3-kinase-Akt pathway is inhibited by C2-ceramide in CAD cells. The European journal of neuroscience. vol 25. issue 10. 2007-08-17. PMID:17561816. |
we tested the hypothesis that insulin-like growth factor-1 (igf-1) could mediate a metabolic response in cad cells, a dopaminergic cell line of mesencephalic origin that differentiate into a neuronal-like phenotype upon serum removal, extend processes resembling neurites, synthesize abundant dopamine and noradrenaline and express the catecholaminergic biosynthetic enzymes tyrosine hydroxylase and dopamine beta-hydroxylase, and that this process was phosphatidylinositol 3-kinase (pi 3-k)-akt-dependent and could be inhibited by c(2)-ceramide. |
2007-08-17 |
2023-08-12 |
Not clear |