| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Olga V Poisik, Yoland Smith, P Jeffrey Con. D1- and D2-like dopamine receptors regulate signaling properties of group I metabotropic glutamate receptors in the rat globus pallidus. The European journal of neuroscience. vol 26. issue 4. 2007-10-25. PMID:17672856. |
dopamine is essential to the proper functioning of basal ganglia (bg) because loss of dopaminergic input profoundly alters the activity of these nuclei. |
2007-10-25 |
2023-08-12 |
rat |
| S Karakaya, M Kipp, C Beye. Oestrogen regulates the expression and function of dopamine transporters in astrocytes of the nigrostriatal system. Journal of neuroendocrinology. vol 19. issue 9. 2007-10-23. PMID:17680883. |
from previous studies, we know that oestrogen regulates the efficacy of dopaminergic neurones at the synaptic level and improves dopamine function during parkinson's disease. |
2007-10-23 |
2023-08-12 |
Not clear |
| Rajesh Pahw. Understanding Parkinson's disease: an update on current diagnostic and treatment strategies. Journal of the American Medical Directors Association. vol 7. issue 7 Suppl 2. 2007-10-22. PMID:17948613. |
pharmacologic therapies are primarily targeted at stimulating dopaminergic receptors, either by increasing the levels of dopamine or by using dopamine agonists. |
2007-10-22 |
2023-08-12 |
Not clear |
| Winona Ts. Optimizing pharmacotherapy: strategies to manage the wearing-off phenomenon. Journal of the American Medical Directors Association. vol 7. issue 7 Suppl 2. 2007-10-22. PMID:17948614. |
motor complications are believed to be due to the progressive loss of dopaminergic neurons that results in a decreased ability to buffer fluctuations in dopamine levels in the brain,coupled with the short half-life of levodopa. |
2007-10-22 |
2023-08-12 |
Not clear |
| Keiko Imamura, Takao Takeshima, Kazuhiro Nakaso, Kenji Nakashim. Homocysteine is toxic for dopaminergic neurons in primary mesencephalic culture. Neuroreport. vol 18. issue 13. 2007-10-19. PMID:17762705. |
in dopaminergic neurons, 5 microm reserpine enhanced the hcy toxicity, whereas 50 microm alpha-methyltyrosine attenuated the toxic effect, showing that the intracellular dopamine increased the cytotoxicity of hcy. |
2007-10-19 |
2023-08-12 |
Not clear |
| Svenja Happe, Cornelius G Bachmann, Kathrin Helmschmied, Karin Neubert, Wolfgang Wuttke, Walter Paulus, Claudia Trenkwalde. Growth hormone response to low-dose apomorphine in restless legs syndrome. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 17. issue 4. 2007-10-18. PMID:17512770. |
this was interpreted as an increased postsynaptic sensitivity of hypothalamic dopamine receptors in the course of a generalized degeneration of dopaminergic neurons. |
2007-10-18 |
2023-08-12 |
Not clear |
| A Storch, Y-I Hwang, G Bringmann, D Feineis, S Ott, R Brückner, J Schwar. Cytotoxicity of chloral-derived beta-carbolines is not specific towards neuronal nor dopaminergic cells. Journal of neural transmission (Vienna, Austria : 1996). vol 113. issue 12. 2007-10-17. PMID:16868795. |
here we examine the dopaminergic toxicity of taclo and related compounds by testing their differential cytotoxicities in dopaminergic sh-sy5y and non-dopaminergic murine neuro2a neuroblastoma cell lines as well as in heterologous expression systems of the dopamine transporter (dat) using both hek-293 and neuro2a cells. |
2007-10-17 |
2023-08-12 |
Not clear |
| b' Leonid Yavich, Markus M Forsberg, Maria Karayiorgou, Joseph A Gogos, Pekka T M\\xc3\\xa4nnist\\xc3\\xb. Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 38. 2007-10-11. PMID:17881525.' |
cocaine affected equally dopaminergic neurotransmission in the prefrontal cortex in both genotypes by prolonging 3-4 times dopamine elimination from extracellular space. |
2007-10-11 |
2023-08-12 |
mouse |
| b' Leonid Yavich, Markus M Forsberg, Maria Karayiorgou, Joseph A Gogos, Pekka T M\\xc3\\xa4nnist\\xc3\\xb. Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 38. 2007-10-11. PMID:17881525.' |
the present findings represent the first demonstration of the significant contribution of comt in modulating the dynamics of dopamine overflow in the prefrontal cortex and underscore the therapeutic potential of manipulating comt activity to alter dopaminergic neurotransmission in the prefrontal cortex. |
2007-10-11 |
2023-08-12 |
mouse |
| Evan D Morris, Karmen K Yode. Positron emission tomography displacement sensitivity: predicting binding potential change for positron emission tomography tracers based on their kinetic characteristics. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 27. issue 3. 2007-10-04. PMID:16788713. |
a tracer-specific predictor, the pet displacement sensitivity (pds), is calculated from compartmental model simulations of the uptake and retention of dopaminergic radiotracers in the presence of transient elevations of dopamine (da). |
2007-10-04 |
2023-08-12 |
Not clear |
| David Nutt, Koen Demyttenaere, Zoltan Janka, Trond Aarre, Michel Bourin, Pier Luigi Canonico, Jose Luis Carrasco, Steven Stah. The other face of depression, reduced positive affect: the role of catecholamines in causation and cure. Journal of psychopharmacology (Oxford, England). vol 21. issue 5. 2007-10-04. PMID:17050654. |
dopaminergic and noradrenergic agents, including the dual acting norepinephrine and dopamine re-uptake inhibitors, have demonstrated antidepressant activity in the absence of serotonergic function, showing similar efficacy to both tricyclic and serotonin re-uptake inhibitor antidepressants. |
2007-10-04 |
2023-08-12 |
Not clear |
| Frank J S Lee, Lin Pei, Anna Moszczynska, Brian Vukusic, Paul J Fletcher, Fang Li. Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor. The EMBO journal. vol 26. issue 8. 2007-10-04. PMID:17380124. |
one of the key presynaptic components involved in regulating dopaminergic tone is the dopamine transporter (dat). |
2007-10-04 |
2023-08-12 |
mouse |
| Justin M Kita, Lauren E Parker, Paul E M Phillips, Paul A Garris, R Mark Wightma. Paradoxical modulation of short-term facilitation of dopamine release by dopamine autoreceptors. Journal of neurochemistry. vol 102. issue 4. 2007-10-04. PMID:17663751. |
electrophysiological studies have demonstrated that dopaminergic neurons burst fire during certain aspects of reward-related behavior; however, the correlation between dopamine release and cell firing is unclear. |
2007-10-04 |
2023-08-12 |
rat |
| Walter Paulus, Pascal Dowling, Roselyne Rijsman, Karin Stiasny-Kolster, Claudia Trenkwalder, Al de Weer. Pathophysiological concepts of restless legs syndrome. Movement disorders : official journal of the Movement Disorder Society. vol 22. issue 10. 2007-10-03. PMID:17516488. |
the concept agreed on assumes a dysfunction of the dopaminergic system, possibly on the level of striatal and/or spinal dopamine receptors, and the a11 neuron group localized in the hypothalamus as an integrated part of the system. |
2007-10-03 |
2023-08-12 |
Not clear |
| Joanna I Udo de Haes, R Paul Maguire, Piet L Jager, Anne M J Paans, Johan A den Boe. Methylphenidate-induced activation of the anterior cingulate but not the striatum: a [15O]H2O PET study in healthy volunteers. Human brain mapping. vol 28. issue 7. 2007-10-02. PMID:17080442. |
in this pilot study we investigated the suitability of the dopamine reuptake blocker methylphenidate (mp) as a dopaminergic probe. |
2007-10-02 |
2023-08-12 |
human |
| Giuliana Zega, Roberta Pennati, Arianna Fanzago, Fiorenza De Bernard. Serotonin involvement in the metamorphosis of the hydroid Eudendrium racemosum. The International journal of developmental biology. vol 51. issue 4. 2007-10-02. PMID:17554682. |
dopamine and all dopaminergic drugs used did not show any significant effect on the onset of metamorphosis. |
2007-10-02 |
2023-08-12 |
Not clear |
| James M Tepper, Christian R Le. GABAergic control of substantia nigra dopaminergic neurons. Progress in brain research. vol 160. 2007-09-28. PMID:17499115. |
inhibition of pallidal output leads to a slight decrease in firing of the dopaminergic neurons due to disinhibition of the pars reticulata neurons whereas increased firing of pallidal neurons leads to burst firing in dopaminergic neurons that is associated with a modest increase in spontaneous firing rate and a significant increase in extracellular levels of dopamine in the neostriatum. |
2007-09-28 |
2023-08-12 |
Not clear |
| Leann P Quinn, Marion J Perren, Kim T Brackenborough, Peter L Woodhams, Martin Vidgeon-Hart, Helen Chapman, Menelas N Pangalos, Neil Upton, David J Virle. A beam-walking apparatus to assess behavioural impairments in MPTP-treated mice: pharmacological validation with R-(-)-deprenyl. Journal of neuroscience methods. vol 164. issue 1. 2007-09-27. PMID:17498809. |
in addition, mptp-treated mice were detected to have a marked depletion in striatal dopamine levels and a concomitant reduction in substantia nigra (sn) tyrosine hydroxylase (th) immunoreactivity, at 7 days post-mptp administration, indicative of dopaminergic neuronal loss. |
2007-09-27 |
2023-08-12 |
mouse |
| Susana R Valdez, Alicia B Penissi, Ricardo P Deis, Graciela A Jah. Hormonal profile and reproductive performance in lactation deficient (OFA hr/hr) and normal (Sprague-Dawley) female rats. Reproduction (Cambridge, England). vol 133. issue 4. 2007-09-26. PMID:17504926. |
dopaminergic metabolism was assessed by determination of mediobasal hypothalamic dopamine and dihydroxyphenylacetic acid (dopac) concentrations by hplc and tyrosine hydroxylase expression by immunocytochemistry and western blot. |
2007-09-26 |
2023-08-12 |
rat |
| Tohru Kitada, Antonio Pisani, Douglas R Porter, Hiroo Yamaguchi, Anne Tscherter, Giuseppina Martella, Paola Bonsi, Chen Zhang, Emmanuel N Pothos, Jie She. Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 27. 2007-09-26. PMID:17563363. |
we found that numbers of dopaminergic neurons and levels of striatal dopamine (da) and da receptors are unchanged in pink1(-/-) mice. |
2007-09-26 |
2023-08-12 |
mouse |