All Relations between dopaminergic and substantia nigra compacta

Publication Sentence Publish Date Extraction Date Species
Tiziano Balzano, Natalia López-González Del Rey, Noelia Esteban-García, Alejandro Reinares-Sebastián, José A Pineda-Pardo, Inés Trigo-Damas, José A Obeso, Javier Bles. Neurovascular and immune factors of vulnerability of substantia nigra dopaminergic neurons in non-human primates. NPJ Parkinson's disease. vol 10. issue 1. 2024-06-19. PMID:38886348. dopaminergic neurons in the ventral tier of the substantia nigra pars compacta (snc) degenerate prominently in parkinson's disease (pd), while those in the dorsal tier and ventral tegmental area are relatively spared. 2024-06-19 2024-06-21 monkey
Patrick Oluwole Abolarin, Abdulbasit Amin, Abdulrazaq Bidemi Nafiu, Olalekan Michael Ogundele, Bamidele Victor Owoyel. Optimization of Parkinson's disease therapy with plant extracts and nutrition's evolving roles. IBRO neuroscience reports. vol 17. 2024-06-14. PMID:38872839. parkinson's disease (pd) is a neurodegenerative disease characterized by death of dopaminergic neurons in the substantia nigra pars compacta (snpc). 2024-06-14 2024-06-16 Not clear
Jane E Manganaro, Katy Emanuel, Benjamin G Lamberty, Joseph W George, Kelly L Stauc. Pink1/Parkin deficiency alters circulating lymphocyte populations and increases platelet-T cell aggregates in rats. Research square. 2024-06-10. PMID:38854001. parkinson's disease (pd) is the most common progressive neurodegenerative movement disorder and results from the selective loss of dopaminergic neurons in the substantia nigra pars compacta. 2024-06-10 2024-06-14 rat
Jiayu Chen, Qinghao Meng, Yuruo Zhang, Yue Liang, Jianhua Ding, Xian Xia, Gang H. TrueTH: A user-friendly deep learning approach for robust dopaminergic neuron detection. Neuroscience letters. 2024-06-10. PMID:38857698. parkinson's disease (pd) entails the progressive loss of dopaminergic (da) neurons in the substantia nigra pars compacta (snc), leading to movement-related impairments. 2024-06-10 2024-06-14 Not clear
Demetra Ballardin, Leila Makrini-Maleville, Alexander Seper, Emmanuel Valjent, Heike Rebhol. 5-HT4R agonism reduces L-DOPA-induced dyskinesia via striatopallidal neurons in unilaterally 6-OHDA lesioned mice. Neurobiology of disease. 2024-06-09. PMID:38852753. parkinson's disease is caused by a selective vulnerability and cell loss of dopaminergic neurons of the substantia nigra pars compacta and, consequently, striatal dopamine depletion. 2024-06-09 2024-06-14 mouse
Diana A Quintero-Espinosa, Marlene Jimenez-Del-Rio, Carlos Velez-Pard. LRRK2 Kinase Inhibitor PF-06447475 Protects Drosophila melanogaster against Paraquat-Induced Locomotor Impairment, Life Span Reduction, and Oxidative Stress. Neurochemical research. 2024-06-07. PMID:38847910. parkinson's disease (pd) is a complex multifactorial progressive neurodegenerative disease characterized by locomotor alteration due to the specific deterioration of dopaminergic (daergic) neurons in the substantia nigra pars compacta (snpc). 2024-06-07 2024-06-10 human
Ozge Akyazı, Dılara Korkmaz, Sule Coskun Cevhe. Experimental Parkinson Models and Green Chemistry Approach. Behavioural brain research. 2024-06-06. PMID:38844056. motor findings in parkinson's occur as a result of the degeneration of dopaminergic neurons starting in the substantia nigra pars compacta and ending in the putamen and caudate nucleus. 2024-06-06 2024-06-10 Not clear
Yangjing Lv, Miaoliang Fan, Jiayan He, Xiaoxin Song, Jianan Guo, Bianbian Gao, Jingqi Zhang, Changjun Zhang, YuanYuan Xi. Discovery of novel benzimidazole derivatives as selective and reversible monoamine oxidase B inhibitors for Parkinson's disease treatment. European journal of medicinal chemistry. vol 274. 2024-06-05. PMID:38838545. parkinson's disease (pd) is a common neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. 2024-06-05 2024-06-08 human
Tania Arora, Gaurav Sharma, Vikash Prashar, Randeep Singh, Arti Sharma, Harish Changotra, Jyoti Parkas. Mechanistic Evaluation of miRNAs and Their Targeted Genes in the Pathogenesis and Therapeutics of Parkinson's Disease. Molecular neurobiology. 2024-06-01. PMID:38823001. pd is mainly caused by the demolition of the primary dopamine neurotransmitter secretory cells and dopaminergic or dopamine secretory neurons in the substantia nigra pars compacta of the midbrain, which are majorly responsible for motor functions. 2024-06-01 2024-06-03 Not clear
Suelen L Boschen, Julian Seethaler, Shaohua Wang, Wendy D Lujan, Jodi L Silvernail, Rickey E Carter, Su-Youne Chang, J Luis Luja. Midbrain dopaminergic degeneration differentially modulates primary motor cortex activity and motor behavior in hemi-parkinsonian rats. Research square. 2024-05-27. PMID:38798359. the modulation of m1 neuronal activity by dopaminergic inputs, particularly from the ventral tegmental area (vta) and substantia nigra pars compacta (snc), plays a crucial role in pd pathophysiology. 2024-05-27 2024-05-31 rat
Md Sadique Hussain, Ehssan Moglad, Muhammad Afzal, Shilpa Sharma, Gaurav Gupta, G V Sivaprasad, Mahamedha Deorari, Waleed Hassan Almalki, Imran Kazmi, Sami I Alzarea, Moyad Shahwan, Kumud Pant, Haider Ali, Sachin Kumar Singh, Kamal Dua, Vetriselvan Subramaniya. Autophagy-associated non-coding RNAs: Unraveling their impact on Parkinson's disease pathogenesis. CNS neuroscience & therapeutics. vol 30. issue 5. 2024-05-25. PMID:38790149. parkinson's disease (pd) is a degenerative neurological condition marked by the gradual loss of dopaminergic neurons in the substantia nigra pars compacta. 2024-05-25 2024-05-27 Not clear
Xinxin Zhao, Zhengwei Kang, Ruixue Han, Min Wang, Yueping Wang, Xin Sun, Cong Wang, Jianwei Zhou, Lei Cao, Ming L. JWA binding to NCOA4 alleviates degeneration in dopaminergic neurons through suppression of ferritinophagy in Parkinson's disease. Redox biology. vol 73. 2024-05-24. PMID:38744191. parkinson's disease (pd) poses a significant challenge in neurodegenerative disorders, characterized by the progressive loss of dopaminergic (da) neurons in the substantia nigra pars compacta (snc). 2024-05-24 2024-05-27 mouse
Xiaodan Ma, Fei Cao, Jing Cui, Xuezhi Li, Zuojuan Yin, Yili Wu, Qinqin Wan. Orexin B protects dopaminergic neurons from 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity associated with reduced extracellular signal-regulated kinase phosphorylation. Molecular biology reports. vol 51. issue 1. 2024-05-24. PMID:38787465. the loss of dopaminergic (da) neurons in the substantia nigra pars compacta (snpc) is a major pathological hallmark of parkinson's disease (pd). 2024-05-24 2024-05-27 Not clear
Fernanda Vidal Carvalho, Harold E Landis, Bruk Getachew, Victor Diogenes Amaral Silva, Paulo R Ribeiro, Michael Aschner, Yousef Tizab. Iron toxicity, ferroptosis and microbiota in Parkinson's disease: Implications for novel targets. Advances in neurotoxicology. vol 11. 2024-05-23. PMID:38770370. parkinson's disease (pd) is a progressive neurodegenerative disease characterized by loss of dopaminergic neurons in substantia nigra pars compacta (snpc). 2024-05-23 2024-05-27 Not clear
Xiang Tao, Wenfei Zhang, Chen Chen, Yang Tao, Yun Tao, Zhibiao Chen, Ge Zhan. miR-101a-3p/ROCK2 axis regulates neuronal injury in Parkinson's disease models. Aging. vol 16. 2024-05-22. PMID:38775730. parkinson's disease (pd) is a neurodegenerative disease characterized by the loss of dopaminergic neurons in substantia nigra pars compacta (snpc). 2024-05-22 2024-05-27 Not clear
Utkarsh Tripathi, Idan Rosh, Ran Ben Ezer, Ritu Nayak, Yara Hussein, Ashwani Choudhary, Jose Djamus, Andreea Manole, Henry Houlden, Fred H Gage, Shani Ster. Upregulated ECM genes and increased synaptic activity in Parkinson's human DA neurons with PINK1/ PRKN mutations. NPJ Parkinson's disease. vol 10. issue 1. 2024-05-21. PMID:38762512. primary symptoms of pd arise with the loss of dopaminergic (da) neurons in the substantia nigra pars compacta, but pd also affects the hippocampus and cortex, usually in its later stage. 2024-05-21 2024-05-27 human
Yu'an Li, Chunlei Yu, Xiaobing Jiang, Jia Fu, Ning Sun, Daquan Zhan. The mechanistic view of non-coding RNAs as a regulator of inflammatory pathogenesis of Parkinson's disease. Pathology, research and practice. vol 258. 2024-05-21. PMID:38772115. parkinson's disease (pd) is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta, leading to motor and non-motor symptoms. 2024-05-21 2024-05-27 Not clear
Yash Wardhan, Sukriti Vishwas, Arumugam Porselvi, Sachin Kumar Singh, Violina Kakot. Exploring the complex interplay between Parkinson's Disease and BAG proteins. Behavioural brain research. 2024-05-20. PMID:38768687. parkinsons disease (pd) is a chronic fast growing neurodegenerative disorder of central nervous system (cns) characterized by progressive loss of dopaminergic neurons in the substantia nigra pars compacta (snpc) and formation of lewy bodies (lbs) which causes dopamine deficiency within basal ganglia leading to motor and non-motor manifestation. 2024-05-20 2024-05-27 Not clear
Weixiao Huang, Tao Zhang, Xiaodi Li, Leilei Gong, Yu Zhang, Chengcheng Luan, Qi Shan, Xiaosong Gu, Lili Zha. Intranasal administration of umbilical cord mesenchymal stem cell exosomes alleviates Parkinson's disease. Neuroscience. 2024-05-05. PMID:38705349. this disease is typically characterized by the formation of lewy bodies in multiple brain regions and dopaminergic neuronal loss in the substantia nigra pars compacta, resulting in non-motor symptoms (e.g., olfactory deficits) and motor dysfunction in the late stages. 2024-05-05 2024-05-08 mouse
Weixiao Huang, Tao Zhang, Xiaodi Li, Leilei Gong, Yu Zhang, Chengcheng Luan, Qi Shan, Xiaosong Gu, Lili Zha. Intranasal administration of umbilical cord mesenchymal stem cell exosomes alleviates Parkinson's disease. Neuroscience. 2024-05-05. PMID:38705349. finally, the activity of olfactory bulb neurons was improved and the loss of dopaminergic neurons in the substantia nigra pars compacta was reversed. 2024-05-05 2024-05-08 mouse