| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rogneda B Kazanskaya, Nikita P Ilyin, Denis A Abaimov, Ksenia A Derzhavina, Konstantin A Demin, Allan V Kalueff, Raul R Gainetdinov, Alexander V Lopache. Chronic digoxin exposure causes hyperactivity, anxiolysis, and alters brain monoamine content in zebrafish (Danio rerio). Neuroreport. vol 36. issue 1. 2024-12-09. PMID:39651715. |
deficits in monoaminergic (dopaminergic, serotonergic, and noradrenergic) neurotransmission are a key pathogenetic factor for multiple neuropsychiatric and neurodegenerative diseases. |
2024-12-09 |
2024-12-12 |
zebrafish |
| Melissa Hernández-Frausto, Carmen Viva. Entorhinal cortex-hippocampal circuit connectivity in health and disease. Frontiers in human neuroscience. vol 18. 2024-10-07. PMID:39372192. |
recent evidence shows that both ec and hc receive inputs from dopaminergic, cholinergic, and noradrenergic projections that modulate the mnemonic processes linked to the encoding and consolidation of memories. |
2024-10-07 |
2024-10-09 |
Not clear |
| Alex I Wiesman, Victoria Madge, Edward A Fon, Alain Dagher, D Louis Collins, Sylvain Baille. Associations between neuromelanin depletion and cortical rhythmic activity in Parkinson's disease. Brain : a journal of neurology. 2024-09-16. PMID:39282945. |
specifically, attention-related alpha activity is related to dysfunction of the noradrenergic system, and beta activity with relevance to motor impairments reflects dopaminergic dysfunction. |
2024-09-16 |
2024-09-19 |
Not clear |
| Alex I Wiesman, Victoria Madge, Edward A Fon, Alain Dagher, D Louis Collins, Sylvain Baille. Associations between neuromelanin depletion and cortical rhythmic activity in Parkinson's disease. Brain : a journal of neurology. 2024-09-16. PMID:39282945. |
parkinson's disease (pd) is marked by the death of neuromelanin-rich dopaminergic and noradrenergic cells in the substantia nigra (sn) and the locus coeruleus (lc), respectively, resulting in motor and cognitive impairments. |
2024-09-16 |
2024-09-19 |
Not clear |
| C Saiz-Masvidal, V De la Peña-Arteaga, S Bertolín, I Martínez-Zalacaín, A Juaneda-Seguí, P Chavarría-Elizondo, M Subirà, J M Menchón, M A Fullana, C Soriano-Ma. Uncovering the correlation between neurotransmitter-specific functional connectivity and multidimensional anxiety in a non-clinical cohort. European archives of psychiatry and clinical neuroscience. 2024-08-27. PMID:39190041. |
resting-state functional magnetic resonance imaging data were acquired, focusing on seven brainstem regions representing serotonergic, dopaminergic, and noradrenergic nuclei, with their fc patterns voxel-wise correlated with the scales. |
2024-08-27 |
2024-08-30 |
human |
| Kenneth Wengler, Paula Trujillo, Clifford M Cassidy, Guillermo Horg. Neuromelanin-sensitive MRI for mechanistic research and biomarker development in psychiatry. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-08-19. PMID:39160355. |
this mri modality is sensitive to the concentration of neuromelanin, which is synthesized from intracellular catecholamines and accumulates in catecholaminergic nuclei including the dopaminergic substantia nigra and the noradrenergic locus coeruleus. |
2024-08-19 |
2024-08-22 |
Not clear |
| Jeremy Metha, Yijun Ji, Clemens Braun, Janet R Nicholson, Luis De Lecea, Carsten Murawski, Daniel Hoyer, Laura H Jacobso. Hypocretin-1 receptor antagonism improves inhibitory control during the Go/No-Go task in highly motivated, impulsive male mice. Psychopharmacology. 2024-06-17. PMID:38886189. |
motivation and inhibitory control are dominantly regulated by the dopaminergic (da) and noradrenergic (na) systems, respectively. |
2024-06-17 |
2024-06-21 |
mouse |
| Brian H Kopell, Deepak A Kaji, Lora E Liharska, Eric Vornholt, Alissa Valentine, Anina Lund, Alice Hashemi, Ryan C Thompson, Terry Lohrenz, Jessica S Johnson, Nicole Bussola, Esther Cheng, You Jeong Park, Punit Shah, Weiping Ma, Richard Searfoss, Salman Qasim, Gregory M Miller, Nischal Mahaveer Chand, Alisha Aristel, Jack Humphrey, Lillian Wilkins, Kimia Ziafat, Hannah Silk, Lisa M Linares, Brendan Sullivan, Claudia Feng, Seth R Batten, Dan Bang, Leonardo S Barbosa, Thomas Twomey, Jason P White, Marina Vannucci, Beniamino Hadj-Amar, Vanessa Cohen, Prashant Kota, Emily Moya, Marysia-Kolbe Rieder, Martijn Figee, Girish N Nadkarni, Michael S Breen, Kenneth T Kishida, Joseph Scarpa, Douglas M Ruderfer, Niven R Narain, Pei Wang, Michael A Kiebish, Eric E Schadt, Ignacio Saez, P Read Montague, Noam D Beckmann, Alexander W Charne. Multiomic foundations of human prefrontal cortex tissue function. medRxiv : the preprint server for health sciences. 2024-05-27. PMID:38798344. |
rna transcript expression within multiple pfc cell types was associated with fluctuations of dopaminergic, serotonergic, and/or noradrenergic neurotransmission in the substantia nigra measured while participants played a computer game that engaged higher-order brain functions. |
2024-05-27 |
2024-05-31 |
human |
| Roisin A Moloney, Hannah K Palliser, Rebecca M Dyson, Carlton L Pavy, Max Berry, Jonathon J Hirst, Julia C Sha. Ongoing effects of preterm birth on the dopaminergic and noradrenergic pathways in the frontal cortex and hippocampus of guinea pigs. Developmental neurobiology. 2024-03-25. PMID:38526217. |
ongoing effects of preterm birth on the dopaminergic and noradrenergic pathways in the frontal cortex and hippocampus of guinea pigs. |
2024-03-25 |
2024-03-27 |
Not clear |
| Felix Langerscheidt, Michael Bell-Simons, Hans Zempe. Differentiating SH-SY5Y Cells into Polarized Human Neurons for Studying Endogenous and Exogenous Tau Trafficking: Four Protocols to Obtain Neurons with Noradrenergic, Dopaminergic, and Cholinergic Properties. Methods in molecular biology (Clifton, N.J.). vol 2754. 2024-03-21. PMID:38512687. |
differentiating sh-sy5y cells into polarized human neurons for studying endogenous and exogenous tau trafficking: four protocols to obtain neurons with noradrenergic, dopaminergic, and cholinergic properties. |
2024-03-21 |
2024-03-24 |
human |
| Felix Langerscheidt, Michael Bell-Simons, Hans Zempe. Differentiating SH-SY5Y Cells into Polarized Human Neurons for Studying Endogenous and Exogenous Tau Trafficking: Four Protocols to Obtain Neurons with Noradrenergic, Dopaminergic, and Cholinergic Properties. Methods in molecular biology (Clifton, N.J.). vol 2754. 2024-03-21. PMID:38512687. |
here, we describe and discuss a general cultivation procedure as well as four differentiation methods to obtain sh-sy5y-derived neurons resembling noradrenergic, dopaminergic, and cholinergic properties, based on the treatment with retinoic acid (ra), brain-derived neurotrophic factor (bdnf), and 12-o-tetrade canoylphorbol-13-acetate (tpa). |
2024-03-21 |
2024-03-24 |
human |
| Helamã Moraes Dos Santos, Amanda Gollo Bertollo, Maiqueli Eduarda Dama Mingoti, Roberta Eduarda Grolli, Kelli Maria Kreuz, Zuleide Maria Ignáci. Dementia and depression: Biological connections with amyloid β protein. Basic & clinical pharmacology & toxicology. 2024-03-09. PMID:38459754. |
small extracellular senile plaques composed of filamentous aggregates of amyloid β (aβ) protein tend to bind to neuronal receptors, affecting cholinergic, serotonergic, dopaminergic and noradrenergic neurotransmission, leading to neuroinflammation, among other pathophysiologic processes and subsequent neuronal death, followed by dementia. |
2024-03-09 |
2024-03-11 |
Not clear |
| Yayun Yan, Mengchao Zhang, Wenhua Ren, Xiaoqi Zheng, Ying Chan. Neuromelanin-sensitive magnetic resonance imaging: Possibilities and promises as an imaging biomarker for Parkinson's disease. The European journal of neuroscience. 2024-03-05. PMID:38441250. |
parkinson's disease (pd) is an age-related progressive neurodegenerative disorder characterized by both motor and non-motor symptoms resulting from the death of dopaminergic neurons in the substantia nigra pars compacta (snpc) and noradrenergic neurons in the locus coeruleus (lc). |
2024-03-05 |
2024-03-07 |
Not clear |
| Alex I Wiesman, Victoria Madge, Edward A Fon, Alain Dagher, D Louis Collins, Sylvain Baille. Associations between neuromelanin depletion and cortical rhythmic activity in Parkinson's disease. medRxiv : the preprint server for health sciences. 2024-02-26. PMID:38405952. |
parkinson's disease (pd) is marked by the death of neuromelanin-rich dopaminergic and noradrenergic cells in the substantia nigra (sn) and the locus coeruleus (lc), respectively, resulting in motor and cognitive impairments. |
2024-02-26 |
2024-02-28 |
Not clear |
| Alex I Wiesman, Victoria Madge, Edward A Fon, Alain Dagher, D Louis Collins, Sylvain Baille. Associations between neuromelanin depletion and cortical rhythmic activity in Parkinson's disease. medRxiv : the preprint server for health sciences. 2024-02-26. PMID:38405952. |
specifically, attention-related alpha activity reflects dysfunction of the noradrenergic system, and beta activity with relevance to motor impairments reflects dopaminergic dysfunction. |
2024-02-26 |
2024-02-28 |
Not clear |
| Stephanie L Grella, Tia N Donaldso. Contextual memory engrams, and the neuromodulatory influence of the locus coeruleus. Frontiers in molecular neuroscience. vol 17. 2024-02-20. PMID:38375501. |
we then outline a recent hypothesis involving noradrenergic and dopaminergic projections from the locus coeruleus (lc) to different subregions of the hippocampus, in sculpting contextual representations, giving a brief description of the neuroanatomical and physiological properties of the lc. |
2024-02-20 |
2024-02-22 |
Not clear |
| Fabrizio Turiaco, Chiara Cullotta, Federica Mannino, Antonio Bruno, Francesco Squadrito, Giovanni Pallio, Natasha Irrer. Attention Deficit Hyperactivity Disorder (ADHD) and Polyphenols: A Systematic Review. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338814. |
thus, a neuroinflammatory state may influence the neurotransmitters pathways, such as the noradrenergic, glutamatergic, serotoninergic, and, in particular, dopaminergic ones, whose impairment is strongly associated with attention deficit hyperactivity disorder (adhd). |
2024-02-10 |
2024-02-12 |
Not clear |
| Qiuyu Lv, Xuanyi Wang, Pan Lin, Xiang Wan. Neuromelanin-sensitive magnetic resonance imaging in the study of mental disorder: A systematic review. Psychiatry research. Neuroimaging. vol 339. 2024-02-07. PMID:38325165. |
recent research suggests that neuromelanin-sensitive magnetic resonance imaging (nm-mri) techniques may overcome this limitation by enabling the non-invasive imaging of the substantia nigra (sn)/ ventral tegmental area (vta) dopaminergic and locus coeruleus (lc) noradrenergic systems. |
2024-02-07 |
2024-02-10 |
Not clear |
| Ana Perez-Villalba, María Salomé Sirerol-Piquer, Raúl Soriano-Cantón, Virginia Folgado, Azucena Pérez-Cañamás, Martina Kirstein, Isabel Fariñas, Francisco Pérez-Sánche. Dopaminergic neuron loss in mice due to increased levels of wild-type human α-Synuclein only takes place under conditions of accelerated aging. Scientific reports. vol 14. issue 1. 2024-01-30. PMID:38291230. |
these motor disturbances correlate with reduced dopamine (da) levels, increased da turnover, synaptic terminal loss, and notably, the depletion of dopaminergic neurons in the substantia nigra and noradrenergic neurons in the locus coeruleus. |
2024-01-30 |
2024-02-02 |
mouse |
| E R G Plini, M C Melnychuk, A Harkin, M J Dahl, M McAuslan, S Kühn, R T Boyle, R Whelan, R Andrews, S Düzel, J Drewelies, G G Wagner, U Lindenberger, K Norman, I H Robertson, P M Dockre. Dietary Tyrosine Intake (FFQ) Is Associated with Locus Coeruleus, Attention and Grey Matter Maintenance: An MRI Structural Study on 398 Healthy Individuals of the Berlin Aging Study-II. The journal of nutrition, health & aging. vol 27. issue 12. 2023-12-28. PMID:38151868. |
degradation of the neuromodulatory pathways, (comprising the cholinergic, dopaminergic, serotoninergic and noradrenergic systems) is observed in neurodegenerative diseases and impairs the proper biosynthesis of key neuromodulators from micro-nutrients and amino acids. |
2023-12-28 |
2023-12-30 |
Not clear |