| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohammed Zacky Ariffin, Si Yun Ng, Hamzah Nadia, Darrel Koh, Natasha Loh, Naomi Michiko, Sanjay Khann. Neurokinin1 - cholinergic receptor mechanisms in the medial Septum-Dorsal hippocampus axis mediates experimental neuropathic pain. Neurobiology of pain (Cambridge, Mass.). vol 16. 2024-09-03. PMID:39224764. |
the neurokinin-1 receptors (nk1rs) in the forebrain medial septum (ms) region are localized exclusively on cholinergic neurons that partly project to the hippocampus and the cingulate cortex (cg), regions implicated in nociception. |
2024-09-03 |
2024-09-05 |
rat |
| Eric Fagerli, Charles W Jackson, Iris Escobar, Fernando J Ferrier, Efrain J Perez Lao, Isabel Saul, Jorge Gomez, Kunjan R Dave, Oliver Bracko, Miguel A Perez-Pinzo. Resveratrol Mitigates Cognitive Impairments and Cholinergic Cell Loss in the Medial Septum in a Mouse Model of Gradual Cerebral Hypoperfusion. Antioxidants (Basel, Switzerland). vol 13. issue 8. 2024-08-29. PMID:39199230. |
resveratrol mitigates cognitive impairments and cholinergic cell loss in the medial septum in a mouse model of gradual cerebral hypoperfusion. |
2024-08-29 |
2024-09-01 |
mouse |
| Eric Fagerli, Charles W Jackson, Iris Escobar, Fernando J Ferrier, Efrain J Perez Lao, Isabel Saul, Jorge Gomez, Kunjan R Dave, Oliver Bracko, Miguel A Perez-Pinzo. Resveratrol Mitigates Cognitive Impairments and Cholinergic Cell Loss in the Medial Septum in a Mouse Model of Gradual Cerebral Hypoperfusion. Antioxidants (Basel, Switzerland). vol 13. issue 8. 2024-08-29. PMID:39199230. |
despite these deficits, no hippocampal pathology was observed; however, cholinergic cell loss in the medial septum was significantly increased after gbccas. |
2024-08-29 |
2024-09-01 |
mouse |
| Maciej Zadrozny, Patrycja Drapich, Anna Gasiorowska-Bien, Wiktor Niewiadomski, Charles R Harrington, Claude M Wischik, Gernot Riedel, Grazyna Niewiadomsk. Neuroprotection of Cholinergic Neurons with a Tau Aggregation Inhibitor and Rivastigmine in an Alzheimer's-like Tauopathy Mouse Model. Cells. vol 13. issue 7. 2024-04-12. PMID:38607082. |
immunohistochemical staining and quantification of choline acetyltransferase (chat), tyrosine kinase a (trka)-positive neurons and relative optical intensity (roi) for vesicular acetylcholine transporter (vacht), and acetylcholinesterase (ache) reactivity confirmed reversal of the diminished cholinergic phenotype of interneurons (nucleus accumbens, striatum) and projection neurons (medial septum, nucleus basalis magnocellularis) by hmtm, to a greater extent than by rivastigmine alone in l1 mice. |
2024-04-12 |
2024-04-14 |
mouse |
| Alyssa Kniffin, Miranda Targum, Aryan Patel, Debra A Bangasser, Vinay Parik. Alterations in hippocampal cholinergic dynamics following CRF infusions into the medial septum of male and female rats. Neurochemistry international. 2024-04-11. PMID:38604443. |
alterations in hippocampal cholinergic dynamics following crf infusions into the medial septum of male and female rats. |
2024-04-11 |
2024-04-14 |
rat |
| Csaba Vastagh, Imre Farkas, Veronika Csillag, Masahiko Watanabe, Imre Kalló, Zsolt Liposit. Cholinergic Control of GnRH Neuron Physiology and Luteinizing Hormone Secretion in Male Mice: Involvement of ACh/GABA Cotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 44. issue 12. 2024-03-20. PMID:38320853. |
retrograde viral labeling initiated from gnrh-cre neurons identified the medial septum and the diagonal band of broca as exclusive sites of origin for cholinergic afferents of gnrh neurons. |
2024-03-20 |
2024-03-23 |
mouse |
| Dayan Knox, Vinay Parik. Basal forebrain cholinergic systems as circuits through which traumatic stress disrupts emotional memory regulation. Neuroscience and biobehavioral reviews. 2024-02-03. PMID:38309497. |
cholinergic medial septum and diagonal bands of broca (chms/dbb neurons) are critical for fear extinction. |
2024-02-03 |
2024-02-06 |
Not clear |
| Skylar Cassity, Irene Jungyeon Choi, Billy Howard Gregory, Adeleke Malik Igbasanmi, Sarah Cristi Bickford, Kiara Tyanni Moore, Anna Elisabeth Seraiah, Dylan Layfield, Ehren Lee Newma. Cholinergic modulation of rearing in rats performing a spatial memory task. The European journal of neuroscience. 2024-01-23. PMID:38258622. |
here, to test whether elevated cholinergic tone increases the probability of rearing, we tracked rearing frequency and duration while optogenetically modulating the activity of choline acetyltransferase containing (i.e., acetylcholine producing) neurons of the medial septum in rats performing a spatial working memory task (n = 17 rats). |
2024-01-23 |
2024-01-25 |
rat |
| Lidia I Madrid, Katelyn Hafey, Saurabh Bandhavkar, Gabriela O Bodea, Javier Jimenez-Martin, Michael Milne, Tara L Walker, Geoffrey J Faulkner, Elizabeth J Coulson, Dhanisha J Jhaver. Stimulation of the muscarinic receptor M4 regulates neural precursor cell proliferation and promotes adult hippocampal neurogenesis. Development (Cambridge, England). 2023-12-08. PMID:38063486. |
using a targeted ablation approach, we also show that medial septum (ms) and the diagonal band of broca (dbb) cholinergic neurons support both the survival and morphological maturation of adult-born neurons in the mouse hippocampus. |
2023-12-08 |
2023-12-17 |
mouse |
| Skylar Cassity, Irene Jungyeon Choi, Adeleke Malik Igbasanmi, Sarah Cristi Bickford, Kiara Tyanni Moore, Anna Elisabeth Seraiah, Lilly O'Shea, Dylan Layfield, Ehren Lee Newma. Cholinergic modulation of exploration in rats performing a spatial memory task. bioRxiv : the preprint server for biology. 2023-10-24. PMID:37873370. |
these results indicate that cholinergic neurons in the medial septum have a context dependent effect on exploration, do not promote rearing directly, but may facilitate the rapid encoding of information while rearing. |
2023-10-24 |
2023-11-08 |
rat |
| Rashmi Gamage, Ilaria Rossetti, Garry Niedermayer, Gerald Münch, Yossi Buskila, Erika Gyenges. Chronic neuroinflammation during aging leads to cholinergic neurodegeneration in the mouse medial septum. Journal of neuroinflammation. vol 20. issue 1. 2023-10-14. PMID:37833764. |
chronic neuroinflammation during aging leads to cholinergic neurodegeneration in the mouse medial septum. |
2023-10-14 |
2023-10-15 |
mouse |
| Christos Panagiotis Lisgaras, Helen E Scharfma. Interictal spikes in Alzheimer's disease: Preclinical evidence for dominance of the dentate gyrus and cholinergic control by medial septum. Neurobiology of disease. 2023-09-15. PMID:37714307. |
interictal spikes in alzheimer's disease: preclinical evidence for dominance of the dentate gyrus and cholinergic control by medial septum. |
2023-09-15 |
2023-10-07 |
mouse |
| Alexia Tiberi, Giulia Borgonovo, Giovanna Testa, Paola Pacifico, Ajesh Jacob, Mariachiara Di Caprio, Valentino Totaro, Mariantonietta Calvello, Antonino Cattaneo, Simona Capson. Reversal of neurological deficits by painless nerve growth factor in a mouse model of Rett syndrome. Brain : a journal of neurology. 2023-08-26. PMID:37633263. |
furthermore, when we assessed the phenotypic changes brought forth by (2) a short-term 1-month-long hngfp-treatment, starting at 3 months of age (right after the initial presentation of symptoms), we observed the rescue of a well-known neuronal target population of ngf, cholinergic neurons in the medial septum. |
2023-08-26 |
2023-09-07 |
mouse |
| Junzi Chen, Yu Wang, Cong Chen, Qingyang Zhang, Shuang Wang, Yi Wang, Jiajia Fang, Ying Wan. Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy. Neural regeneration research. vol 18. issue 11. 2023-06-07. PMID:37282477. |
activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy. |
2023-06-07 |
2023-08-14 |
mouse |
| Junzi Chen, Yu Wang, Cong Chen, Qingyang Zhang, Shuang Wang, Yi Wang, Jiajia Fang, Ying Wan. Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy. Neural regeneration research. vol 18. issue 11. 2023-06-07. PMID:37282477. |
medial septum cholinergic neurons have been reported to be a potential target for controlling epileptic seizures in temporal lobe epilepsy. |
2023-06-07 |
2023-08-14 |
mouse |
| Junzi Chen, Yu Wang, Cong Chen, Qingyang Zhang, Shuang Wang, Yi Wang, Jiajia Fang, Ying Wan. Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy. Neural regeneration research. vol 18. issue 11. 2023-06-07. PMID:37282477. |
in a mouse model of chronic temporal lobe epilepsy induced by kainic acid, the number of medial septum cholinergic neurons was reduced and acetylcholine release was reduced in the hippocampus. |
2023-06-07 |
2023-08-14 |
mouse |
| Junzi Chen, Yu Wang, Cong Chen, Qingyang Zhang, Shuang Wang, Yi Wang, Jiajia Fang, Ying Wan. Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy. Neural regeneration research. vol 18. issue 11. 2023-06-07. PMID:37282477. |
furthermore, selective apoptosis of medial septum cholinergic neurons mimicked the cognitive deficits in epileptic mice, and activation of medial septum cholinergic neurons enhanced hippocampal acetylcholine release and restored cognitive function in both kainic acid- and kindling-induced epilepsy models. |
2023-06-07 |
2023-08-14 |
mouse |
| Junzi Chen, Yu Wang, Cong Chen, Qingyang Zhang, Shuang Wang, Yi Wang, Jiajia Fang, Ying Wan. Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy. Neural regeneration research. vol 18. issue 11. 2023-06-07. PMID:37282477. |
these results suggest that activation of medial septum cholinergic neurons reduces cognitive deficits in temporal lobe epilepsy by increasing acetylcholine release via projections to the hippocampus. |
2023-06-07 |
2023-08-14 |
mouse |
| Yuta Madokoro, Daisuke Kato, Yo Tsuda, Itsumi Arakawa, Kengo Suzuki, Toyohiro Sato, Masayuki Mizuno, Yuto Uchida, Kosei Ojika, Noriyuki Matsukaw. Direct Enhancement Effect of Hippocampal Cholinergic Neurostimulating Peptide on Cholinergic Activity in the Hippocampus. International journal of molecular sciences. vol 24. issue 10. 2023-05-27. PMID:37240261. |
the cholinergic efferent network from the medial septal nucleus to the hippocampus is crucial for learning and memory. |
2023-05-27 |
2023-08-14 |
mouse |
| Christos Panagiotis Lisgaras, Helen E Scharfma. Interictal Spikes in Animal Models of Alzheimer's Disease: Dominance of the Dentate Gyrus and Cholinergic Control by Medial Septum. bioRxiv : the preprint server for biology. 2023-05-10. PMID:37163065. |
interictal spikes in animal models of alzheimer's disease: dominance of the dentate gyrus and cholinergic control by medial septum. |
2023-05-10 |
2023-08-14 |
mouse |