| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shereen Nizari, Jack A Wells, Roxana O Carare, Ignacio A Romero, Cheryl A Hawke. Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice. Acta neuropathologica communications. vol 9. issue 1. 2021-11-15. PMID:33413694. |
loss of cholinergic innervation differentially affects enos-mediated blood flow, drainage of aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice. |
2021-11-15 |
2023-08-13 |
mouse |
| Shereen Nizari, Jack A Wells, Roxana O Carare, Ignacio A Romero, Cheryl A Hawke. Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice. Acta neuropathologica communications. vol 9. issue 1. 2021-11-15. PMID:33413694. |
in the present study, intracerebroventricular administration of mu-saporin resulted in significant death of cholinergic neurons and fibres in the medial septum, cortex and hippocampus of c57bl/6 mice. |
2021-11-15 |
2023-08-13 |
mouse |
| Lindsay Collins, Laura Boddington, Paul J Steffan, David McCormic. Vagus nerve stimulation induces widespread cortical and behavioral activation. Current biology : CB. vol 31. issue 10. 2021-11-10. PMID:33740425. |
taken together, our results support a model of vns in which activation of subcortical structures leads to widespread activation of cortex and an increase in arousal state, at least partially due to the activation of cholinergic and noradrenergic modulatory pathways. |
2021-11-10 |
2023-08-13 |
mouse |
| Javier Jimenez-Martin, Daniil Potapov, Kay Potapov, Thomas Knöpfel, Ruth M Empso. Cholinergic modulation of sensory processing in awake mouse cortex. Scientific reports. vol 11. issue 1. 2021-11-09. PMID:34471145. |
cholinergic modulation of sensory processing in awake mouse cortex. |
2021-11-09 |
2023-08-13 |
mouse |
| Javier Jimenez-Martin, Daniil Potapov, Kay Potapov, Thomas Knöpfel, Ruth M Empso. Cholinergic modulation of sensory processing in awake mouse cortex. Scientific reports. vol 11. issue 1. 2021-11-09. PMID:34471145. |
the widespread nature of cholinergic projections to the cortex means that new insights require access to specific neuronal populations, and on a time-scale that matches behaviourally relevant cholinergic actions. |
2021-11-09 |
2023-08-13 |
mouse |
| Paula Moyano, Andrea Flores, Jimena García, José Manuel García, María José Anadon, María Teresa Frejo, Emma Sola, Adela Pelayo, Javier Del Pin. Bisphenol A single and repeated treatment increases HDAC2, leading to cholinergic neurotransmission dysfunction and SN56 cholinergic apoptotic cell death through AChE variants overexpression and NGF/TrkA/P75 Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 157. 2021-11-01. PMID:34655688. |
basal forebrain cholinergic neurons (bfcn) innervate hippocampus and cortex, regulating cognitive function, and their loss or the induction of cholinergic neurotransmission dysfunction leads to cognitive disabilities. |
2021-11-01 |
2023-08-13 |
Not clear |
| Kristian Stær, Alex Iranzo, Morten G Stokholm, Karen Østergaard, Mónica Serradell, Marit Otto, Kristina B Svendsen, Alicia Garrido, Dolores Vilas, Joan Santamaria, Arne Møller, Carles Gaig, David J Brooks, Per Borghammer, Eduardo Tolosa, Nicola Paves. Cortical cholinergic dysfunction correlates with microglial activation in the substantia innominata in REM sleep behavior disorder. Parkinsonism & related disorders. vol 81. 2021-10-29. PMID:33099132. |
this study aimed to explore whether reduced cortical acetylcholinesterase activity in irbd is linked to microglial activation in the substantia innominata (si), the major source of cholinergic input to the cortex. |
2021-10-29 |
2023-08-13 |
Not clear |
| Ahsas Goyal, Debapriya Garabad. Vinpocetine facilitates the anti-amnesic activity of estrogen-receptor alpha agonist in bilateral ovariectomy-challenged animals. Behavioural brain research. vol 393. 2021-10-25. PMID:32593544. |
vinpocetine and ppt increased the cholinergic function and the ratio of cgmp/camp in the hippocampus, pre-frontal cortex and amygdala of the ovariectomized animals. |
2021-10-25 |
2023-08-13 |
rat |
| N I Bohnen, C W Bogan, M L T M Mülle. Frontal and periventricular brain white matter lesions and cortical deafferentation of cholinergic and other neuromodulatory axonal projections. European neurological journal. vol 1. issue 1. 2021-10-21. PMID:22763426. |
a unique anatomic feature common to all cortical projections from subcortical neuromodulator systems (that not only include the cholinergic but also the monoaminergic systems, such as dopamine, serotonin, and norepinephrine) is that the proximal axons largely pass through the deep forebrain before fanning out to the cortex. |
2021-10-21 |
2023-08-12 |
Not clear |
| Jing Qi, Bo-Zhi Li, Ying Zhang, Bei Pan, Yu-Hong Gao, Hao Zhan, Yong Liu, Yong-Cong Shao, Xi Zhan. Altered functional connectivity between the nucleus basalis of Meynert and anterior cingulate cortex is associated with declined attentional performance after total sleep deprivation. Behavioural brain research. vol 409. 2021-10-18. PMID:33910027. |
the nucleus basalis of meynert (nbm), the main source of cholinergic projections to the cortex, plays an important role in wakefulness maintenance and attention control. |
2021-10-18 |
2023-08-13 |
Not clear |
| Jacopo Pasquini, David J Brooks, Nicola Paves. The Cholinergic Brain in Parkinson's Disease. Movement disorders clinical practice. vol 8. issue 7. 2021-10-12. PMID:34631936. |
the central cholinergic system includes the basal forebrain nuclei, mainly projecting to the cortex, the mesopontine tegmental nuclei, mainly projecting to the thalamus and subcortical structures, and other groups of projecting neurons and interneurons. |
2021-10-12 |
2023-08-13 |
human |
| William A Noftz, Nichole L Beebe, Jeffrey G Mellott, Brett R Schofiel. Cholinergic Projections From the Pedunculopontine Tegmental Nucleus Contact Excitatory and Inhibitory Neurons in the Inferior Colliculus. Frontiers in neural circuits. vol 14. 2021-10-04. PMID:32765226. |
on both sides, cholinergic axons were present throughout the inferior colliculus, distributing boutons to the central nucleus, lateral cortex, and dorsal cortex. |
2021-10-04 |
2023-08-13 |
rat |
| Ornela Kljakic, Mohammed Al-Onaizi, Helena Janíčková, Kevin S Chen, Monica S Guzman, Marco A M Prado, Vania F Prad. Cholinergic transmission from the basal forebrain modulates social memory in male mice. The European journal of neuroscience. vol 54. issue 6. 2021-09-24. PMID:34308559. |
we found that when cholinergic signalling is highly disrupted in the striatum, hippocampus, cortex and amygdala mice have intact social preference but are impaired in social memory, as they cannot remember a familiar conspecific nor recognize a novel one. |
2021-09-24 |
2023-08-13 |
mouse |
| Ornela Kljakic, Mohammed Al-Onaizi, Helena Janíčková, Kevin S Chen, Monica S Guzman, Marco A M Prado, Vania F Prad. Cholinergic transmission from the basal forebrain modulates social memory in male mice. The European journal of neuroscience. vol 54. issue 6. 2021-09-24. PMID:34308559. |
together, these data suggest that cholinergic transmission from the hippocampus and cortex are important for regulating social memory. |
2021-09-24 |
2023-08-13 |
mouse |
| Eloïse de Tredern, Yasmine Rabah, Laure Pasquer, Julia Minatchy, Pierre-Yves Plaçais, Thomas Prea. Glial glucose fuels the neuronal pentose phosphate pathway for long-term memory. Cell reports. vol 36. issue 8. 2021-09-04. PMID:34433052. |
in vivo imaging reveals that, downstream of cholinergic activation of cortex glia, autocrine insulin signaling increases glucose concentration in glia. |
2021-09-04 |
2023-08-13 |
drosophila_melanogaster |
| O K Ijomone, O L Erukainure, P Shallie, T Naicke. Neurotoxicity in pre-eclampsia involves oxidative injury, exacerbated cholinergic activity and impaired proteolytic and purinergic activities in cortex and cerebellum. Human & experimental toxicology. vol 40. issue 1. 2021-09-02. PMID:32772714. |
neurotoxicity in pre-eclampsia involves oxidative injury, exacerbated cholinergic activity and impaired proteolytic and purinergic activities in cortex and cerebellum. |
2021-09-02 |
2023-08-13 |
rat |
| Jose L Martinez, Matthew D Zammit, Nicole R West, Bradley T Christian, Anita Bhattacharyy. Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer's Disease. Frontiers in aging neuroscience. vol 13. 2021-08-23. PMID:34322015. |
bfcns are the primary source of cholinergic innervation to the cerebral cortex and hippocampus, as well as the amygdala. |
2021-08-23 |
2023-08-13 |
human |
| Behroo Mirza Agha, Roya Akbary, Arashk Ghasroddashti, Mojtaba Nazari-Ahangarkolaee, Ian Q Whishaw, Majid H Mohajeran. Cholinergic upregulation by optogenetic stimulation of nucleus basalis after photothrombotic stroke in forelimb somatosensory cortex improves endpoint and motor but not sensory control of skilled reaching in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 41. issue 7. 2021-08-20. PMID:33103935. |
cholinergic upregulation by optogenetic stimulation of nucleus basalis after photothrombotic stroke in forelimb somatosensory cortex improves endpoint and motor but not sensory control of skilled reaching in mice. |
2021-08-20 |
2023-08-13 |
mouse |
| Behroo Mirza Agha, Roya Akbary, Arashk Ghasroddashti, Mojtaba Nazari-Ahangarkolaee, Ian Q Whishaw, Majid H Mohajeran. Cholinergic upregulation by optogenetic stimulation of nucleus basalis after photothrombotic stroke in forelimb somatosensory cortex improves endpoint and motor but not sensory control of skilled reaching in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 41. issue 7. 2021-08-20. PMID:33103935. |
this study examined the contribution of the nucleus basalis cholinergic projection to the sensorimotor cortex on recovery on a skilled reach-to-eat task following photothrombotic stroke in the forelimb region of the somatosensory cortex. |
2021-08-20 |
2023-08-13 |
mouse |
| Ceyhan Hacioglu, Fatih Kar, Ezgi Kar, Yakup Kara, Gungor Kanba. Effects of Curcumin and Boric Acid Against Neurodegenerative Damage Induced by Amyloid Beta (1-42). Biological trace element research. vol 199. issue 10. 2021-08-16. PMID:33237490. |
ba and curcumin treatment can have abilities to prevent the alterations of the cholinergic system and inhibit oxidative stress in the cerebral cortex synapses of aβ1-42 exposed. |
2021-08-16 |
2023-08-13 |
rat |