| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fernando R Nodal, Nicholas D Leach, Peter Keating, Johannes C Dahmen, Dylan Zhao, Andrew J King, Victoria M Baj. Neural processing in the primary auditory cortex following cholinergic lesions of the basal forebrain in ferrets. Hearing research. vol 447. 2024-05-11. PMID:38733712. |
to explore whether these behavioral deficits are associated with changes in the response properties of cortical neurons, we recorded neural activity in the primary auditory cortex (a1) of anesthetized ferrets in which cholinergic inputs had been reduced by making bilateral injections of the immunotoxin me20.4-sap in the nucleus basalis (nb) prior to training the animals. |
2024-05-11 |
2024-05-27 |
Not clear |
| Michael K Lee, Gang Che. Loss of Cholinergic and Monoaminergic Afferents in International journal of molecular sciences. vol 25. issue 9. 2024-05-11. PMID:38732223. |
loss of cholinergic and monoaminergic afferents in alzheimer's disease (ad) is characterized by a loss of neurons in the cortex and subcortical regions. |
2024-05-11 |
2024-05-27 |
human |
| Neda Shafiee, Vladimir Fonov, Mahsa Dadar, R Nathan Spreng, D Louis Collin. Degeneration in Nucleus basalis of Meynert signals earliest stage of Alzheimer's disease progression. Neurobiology of aging. vol 139. 2024-04-12. PMID:38608458. |
nucleus basalis of meynert (nbm), a crucial source of cholinergic projection to the entorhinal cortex (ec) and hippocampus (hc), has shown sensitivity to neurofibrillary degeneration in the early stages of alzheimer's disease. |
2024-04-12 |
2024-04-15 |
human |
| Maciej Zadrozny, Patrycja Drapich, Anna Gasiorowska-Bien, Wiktor Niewiadomski, Charles R Harrington, Claude M Wischik, Gernot Riedel, Grazyna Niewiadomsk. Neuroprotection of Cholinergic Neurons with a Tau Aggregation Inhibitor and Rivastigmine in an Alzheimer's-like Tauopathy Mouse Model. Cells. vol 13. issue 7. 2024-04-12. PMID:38607082. |
the strongest phenotypic reversal coincided with a normalization of the tau load in the cortex and hippocampus of l1, suggesting that tau accumulation underpins the loss of cholinergic markers in the basal forebrain and its projection targets. |
2024-04-12 |
2024-04-14 |
mouse |
| Anna Flavia Cantone, Chiara Burgaletto, Giulia Di Benedetto, Anna Pannaccione, Agnese Secondo, Carlo Maria Bellanca, Egle Augello, Antonio Munafò, Paola Tarro, Renato Bernardini, Giuseppina Cantarell. Taming Microglia in Alzheimer's Disease: Exploring Potential Implications of Choline Alphoscerate via α7 nAChR Modulation. Cells. vol 13. issue 4. 2024-02-23. PMID:38391922. |
alzheimer's disease (ad), marked by cognitive impairment, predominantly affects the brain regions regulated by cholinergic innervation, such as the cerebral cortex and hippocampus. |
2024-02-23 |
2024-02-25 |
Not clear |
| Verónica Pastor, Cynthia Katch. Dual role of α7 nicotinic acetylcholine receptors in the retrosplenial cortex for aversive memory acquisition and retrieval. Frontiers in behavioral neuroscience. vol 18. 2024-02-13. PMID:38344272. |
in the retrosplenial cortex (rsc), the role of cholinergic modulation via α7 nicotinic receptors and their involvement in memory is unknown. |
2024-02-13 |
2024-02-15 |
Not clear |
| Mala R Ananth, John D Gardus, Chuan Huang, Nikhil Palekar, Mark Slifstein, Laszlo Zaborszky, Ramin V Parsey, David A Talmage, Christine DeLorenzo, Lorna W Rol. Loss of septal cholinergic input to lateral entorhinal cortex is an early indicator of cognitive impairment. Research square. 2024-01-23. PMID:38260541. |
loss of septal cholinergic input to lateral entorhinal cortex is an early indicator of cognitive impairment. |
2024-01-23 |
2024-01-25 |
mouse |
| Mala R Ananth, John D Gardus, Chuan Huang, Nikhil Palekar, Mark Slifstein, Laszlo Zaborszky, Ramin V Parsey, David A Talmage, Christine DeLorenzo, Lorna W Rol. Loss of septal cholinergic input to lateral entorhinal cortex is an early indicator of cognitive impairment. Research square. 2024-01-23. PMID:38260541. |
we focus on the cholinergic innervation of the entorhinal cortex (ec), a region that is recognized to be susceptible early in aging and neurodegenerative disease. |
2024-01-23 |
2024-01-25 |
mouse |
| Nworie Okoro, Doris Olachi Alilonu, Eze Chinazom Martina, Azubuike Peter Ebokaiw. Aflatoxin B1-induced redox imbalance in the hippocampus and cerebral cortex of male Wistar rats is accompanied by altered cholinergic, indoleaminergic, and purinergic pathways: Abatement by dietary rutin. Toxicon : official journal of the International Society on Toxinology. 2024-01-11. PMID:38211804. |
aflatoxin b1-induced redox imbalance in the hippocampus and cerebral cortex of male wistar rats is accompanied by altered cholinergic, indoleaminergic, and purinergic pathways: abatement by dietary rutin. |
2024-01-11 |
2024-01-14 |
rat |
| Wricha Mishra, Ehsan Kheradpezhouh, Ehsan Arabzade. Activation of M1 cholinergic receptors in mouse somatosensory cortex enhances information processing and detection behaviour. Communications biology. vol 7. issue 1. 2024-01-03. PMID:38168628. |
activation of m1 cholinergic receptors in mouse somatosensory cortex enhances information processing and detection behaviour. |
2024-01-03 |
2024-01-06 |
mouse |
| Jarrod A Gott, Sina Stücker, Philipp Kanske, Jan Haaker, Martin Dresle. Acetylcholine and metacognition during sleep. Consciousness and cognition. vol 117. 2023-12-02. PMID:38042119. |
additionally, acetylcholine is involved in the regulation of rem sleep: cholinergic neurons in the brainstem and basal forebrain project to and innervate wide areas of the cerebral cortex, and reciprocally interact with other neuromodulatory systems, to produce the sleep-wake cycle and different sleep stages. |
2023-12-02 |
2023-12-10 |
Not clear |
| Guangfei Li, Dandan Zhong, Bao Li, Yu Chen, Lin Yang, Chiang-Shan R L. Sleep deficits inter-link lower basal forebrain - posterior cingulate connectivity and perceived stress and anxiety bidirectionally in young men. The international journal of neuropsychopharmacology. 2023-11-04. PMID:37924270. |
the basal nucleus of meynert (bnm), a primary source of cholinergic projections to the cortex, plays key roles in regulating sleep-wake cycle and attention. |
2023-11-04 |
2023-11-08 |
Not clear |
| Sudesna Chakraborty, Sun Kyun Lee, Sarah M Arnold, Roy A M Haast, Ali R Khan, Taylor W Schmit. Focal acetylcholinergic modulation of the human midcingulo-insular network during attention: Meta-analytic neuroimaging and behavioral evidence. Journal of neurochemistry. 2023-10-21. PMID:37864501. |
the basal forebrain cholinergic neurons provide acetylcholine to the cortex via large projections. |
2023-10-21 |
2023-11-08 |
human |
| Rashmi Gamage, Ilaria Rossetti, Garry Niedermayer, Gerald Münch, Yossi Buskila, Erika Gyenges. Chronic neuroinflammation during aging leads to cholinergic neurodegeneration in the mouse medial septum. Journal of neuroinflammation. vol 20. issue 1. 2023-10-14. PMID:37833764. |
the basal forebrain cholinergic neurons (bfcn) provide the primary source of cholinergic innervation of the human cerebral cortex and may be differentially vulnerable in various neurodegenerative diseases. |
2023-10-14 |
2023-10-15 |
mouse |
| Jiajia Sun, Zhi Zhang, Kexin Yang, Gang Wei, Yanxia Li, Shenglong Zhan. Ameliorative effects of pine nut peptide-zinc chelate (Korean pine) on a mouse model of Alzheimer's disease. Experimental gerontology. 2023-10-11. PMID:37821052. |
it may exert its effects by ameliorating decreased ache levels and increased chat levels in the central cholinergic system, endogenous thiol antioxidants (enzymes) in the cerebral cortex, and by controlling the bacterial flora in the gut. |
2023-10-11 |
2023-10-15 |
mouse |
| Meenakshi M Asokan, Yurika Watanabe, Eyal Y Kimchi, Daniel B Polle. Potentiation of cholinergic and corticofugal inputs to the lateral amygdala in threat learning. Cell reports. vol 42. issue 10. 2023-09-24. PMID:37742187. |
the amygdala, cholinergic basal forebrain, and higher-order auditory cortex (ho-ac) regulate brain-wide plasticity underlying auditory threat learning. |
2023-09-24 |
2023-10-07 |
mouse |
| Srestha Dasgupta, Laura Montroull, Mansi Pandya, Juan P Zanin, Wei Wang, Zhuhao Wu, Wilma J Friedma. Cortical Brain Injury Causes Retrograde Degeneration of Afferent Basal Forebrain Cholinergic Neurons via the p75NTR. eNeuro. 2023-08-09. PMID:37558465. |
basal forebrain cholinergic neurons (bfcns) extend long projections to multiple brain regions including the cortex, regulate many cognitive functions and are compromised in numerous neurodegenerative disorders. |
2023-08-09 |
2023-08-16 |
mouse |
| Zhao-Yi Chen, Yao-Lian Yang, Mai Li, Lu Gao, Wei-Min Qu, Zhi-Li Huang, Xiang-Shan Yua. Whole-brain neural connectivity to cholinergic neurons in the nucleus basalis of Meynert. Journal of neurochemistry. 2023-06-24. PMID:37353897. |
moreover, the majority of cholinergic terminals from the nbm were observed in the cortex mantle, including the motor cortex, sensory cortex, and visual cortex. |
2023-06-24 |
2023-08-14 |
mouse |
| Irene Chaves-Coira, Nuria García-Magro, Jonathan Zegarra-Valdivia, Ignacio Torres-Alemán, Ángel Núñe. Cognitive Deficits in Aging Related to Changes in Basal Forebrain Neuronal Activity. Cells. vol 12. issue 11. 2023-06-11. PMID:37296598. |
the cholinergic neurons of the basal forebrain provide projections to the cortex that are directly engaged in many cognitive processes in mammals. |
2023-06-11 |
2023-08-14 |
Not clear |
| Sudesna Chakraborty, Roy A M Haast, Prabesh Kanel, Ali R Khan, Taylor W Schmit. Multimodal gradients of human basal forebrain connectivity. bioRxiv : the preprint server for biology. 2023-06-09. PMID:37292595. |
the cholinergic innervation of the cortex originates almost entirely from populations of neurons in the basal forebrain. |
2023-06-09 |
2023-08-14 |
human |