| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lu Wang, Xin-Tong Su, Na-Na Yang, Qing-Yong Wang, Jing-Wen Yang, Cun-Zhi Li. Electroacupuncture improves cerebral blood flow in pMCAO rats during acute phase via promoting leptomeningeal collaterals. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2025-02-26. PMID:40007441. |
these findings suggest that ea improved cbf after acute ischemic stroke, partially via activating cholinergic projections from the nbm to the cortex, thereby promoting leptomeningeal collateral circulation. |
2025-02-26 |
2025-02-28 |
human |
| Hideki Kondo, Laszlo Zaborszk. Basal Forebrain Projections to the Retrosplenial and Cingulate Cortex in Rats. The Journal of comparative neurology. vol 533. issue 2. 2025-02-10. PMID:39924777. |
in this study, we examined bf cholinergic and non-cholinergic projections to the retrosplenial cortex (rsc) and anterior cingulate cortex (acc) using two retrograde tracers, fast blue (fb) and fluoro-gold (fg), in combination with choline acetyltransferase (chat) immunostaining in rats. |
2025-02-10 |
2025-02-13 |
rat |
| Kevin Thomas, Hamid Azimi, Davide Maggioni, Mark Sanders, Pilar Vaca Sánchez, Michael A Harvey, Gregor Raine. GABAergic neurons in basal forebrain exert frequency-specific modulation on auditory cortex and enhance attentional selection of auditory stimuli. Communications biology. vol 8. issue 1. 2025-02-01. PMID:39890821. |
the basal forebrain (bf), in particular its cholinergic projections to cortex, has been implicated in regulation of attention in sensory systems. |
2025-02-01 |
2025-02-04 |
rat |
| Ana Knezovic, Melita Salkovic-Petrisi. Cholinergic neurotransmission in the brain of streptozotocin-induced rat model of sporadic Alzheimer's disease: long-term follow up. Journal of neural transmission (Vienna, Austria : 1996). 2025-02-01. PMID:39891708. |
the cortex and hippocampus exhibited specific alterations in cholinergic transmission following stz-icv administration, with either similar or distinct patterns depending on the parameter observed: increased ache activity in hpc and invariable in ctx; increased m4 and chat levels in both regions; substantial cortical m1 level increment and moderate hippocampal m1 decrement; and decreased α7 levels in both regions, with subsequent increase observed only in hpc. |
2025-02-01 |
2025-02-04 |
rat |
| Srestha Dasgupta, Mansi A Pandya, Wilma J Friedma. Microfluidic Cultures of Basal Forebrain Cholinergic Neurons for Assessing Retrograde Cell Death by Live Imaging. Bio-protocol. vol 15. issue 1. 2025-01-14. PMID:39803317. |
in the brain, basal forebrain cholinergic neurons (bfcns) possess extensive axons that project to several target regions such as the cortex, hippocampus, and amygdala, and may be exposed to a specific microenvironment in their axon targets that may have retrograde effects on neuronal health. |
2025-01-14 |
2025-01-16 |
Not clear |
| Erika Gyenges. A tribute to Laszlo Zaborszky: pioneering discoveries in the basal forebrain and inspiring generations of neuroscientists. Brain structure & function. vol 230. issue 1. 2024-12-29. PMID:39733215. |
his findings have challenged longstanding assumptions, demonstrating that the cholinergic projections to the cortex are highly organized, with implications for neurodegenerative diseases like alzheimer's. |
2024-12-29 |
2024-12-31 |
Not clear |
| Ana de Figueiredo Pelegrino, Mouna Attarha, Paule-Joanne Toussaint, Lydia Ouellet, Sarah-Jane Grant, Thomas Van Vleet, Etienne de Villers-Sidan. Cholinergic neurotransmission in the anterior cingulate cortex is associated with cognitive performance in healthy older adults: Baseline characteristics of the Improving Neurological Health in Aging via Neuroplasticity-based Computerized Exercise (INHANCE) trial. medRxiv : the preprint server for health sciences. 2024-11-22. PMID:39574863. |
aging is associated with dysfunction in the cholinergic system, including degeneration of basal forebrain cholinergic terminals that innervate the cortex, which directly contributes to age- and disease-related cognitive decline. |
2024-11-22 |
2024-11-24 |
human |
| Donald E Moss, Ruth G Pere. The phospho-tau cascade, basal forebrain neurodegeneration, and dementia in Alzheimer's disease: Anti-neurodegenerative benefits of acetylcholinesterase inhibitors. Journal of Alzheimer's disease : JAD. 2024-11-13. PMID:39533696. |
a conundrum in alzheimer's disease (ad) is why the long-term use of acetylcholinesterase (ache) inhibitors, intended for treatment of dementia, results in slowing neurodegeneration in the cholinergic basal forebrain, hippocampus, and cortex. |
2024-11-13 |
2024-11-17 |
Not clear |
| Abhimannu Shome, Keshav Taruneshwar Jha, Chahat, Viney Chawla, Pooja A Chawl. An Insight into Medicinal Chemistry and SAR Studies of Cholinesterase and BACE-1 Inhibitors for Alzheimer's Disease. CNS & neurological disorders drug targets. 2024-10-17. PMID:39415573. |
alzheimer's disease (ad) is a serious neurodegenerative condition that predominantly impacts the cholinergic neurons of the entorhinal cortex and hippocampal regions, playing a critical role in learning, navigation, and brain processing. |
2024-10-17 |
2024-10-19 |
Not clear |
| Martina Lamberti, Nikolaos Kikirikis, Michel J A M van Putten, Joost le Febe. Impact of background input on memory consolidation. Scientific reports. vol 14. issue 1. 2024-10-10. PMID:39390214. |
this occurs mainly during slow wave sleep, a phase characterized in the cortex by low cholinergic tone and low afferent input. |
2024-10-10 |
2024-10-13 |
Not clear |
| Lindsey Avery Fitzsimons, Mohammad Atif-Sheikh, Jayden Lovely, Madison Mueth, Makaela Rice, Kevin Kotredes, Gareth Howell, Benjamin J Harriso. CD2AP is Co-Expressed with Tropomyosin-Related Kinase A and Ras-Related Protein Rab-5A in Cholinergic Neurons of the Murine Basal Forebrain. bioRxiv : the preprint server for biology. 2024-08-30. PMID:39211110. |
basal forebrain cholinergic neurons project to the hippocampus and cortex, are critical for learning and memory, and are central to the pathogenesis of alzheimer's disease (ad). |
2024-08-30 |
2024-09-04 |
Not clear |
| Vanessa Valéria Miron, Charles Elias Assmann, Vitor Bastianello Mostardeiro, Marcylene Vieira da Silveira, Priscila Marquezan Copetti, Bianca Fagan Bissacotti, Adriel Antonio Schirmann, Milagros Fanny Vera Castro, Jessié Martins Gutierres, Marilda da Cruz Fernandes, Fernanda Tibolla Viero, Vera Maria Morsch, Maria Rosa Chitolina Schetinger, Andréia Machado Cardos. Neuroprotective effect of long-term resistance physical exercise against memory damage elicited by a lipopolysaccharide-induced neuroinflammation model in male rats. Journal of neuroscience research. vol 102. issue 8. 2024-08-19. PMID:39158105. |
the cholinergic system, oxidative stress, and histochemical parameters were analyzed in the cerebral cortex and hippocampus, and memory tests were also performed. |
2024-08-19 |
2024-08-21 |
rat |
| Leslie Doucette, Victoria Turnbill, Katherine Carlin, Andrew Cavanagh, Benjamin Sollinger, Nazli Kuter, Debra L Flock, Shenandoah Robinson, Raul Chavez-Valdez, Lauren Jantzie, Lee J Martin, Frances J Northingto. Neocortical cholinergic pathology after neonatal brain injury is increased by Alzheimer's disease-related genes in mice. Neurobiology of disease. 2024-08-07. PMID:39111704. |
injury to the cholinergic basal forebrain and its rich innervation of cerebral cortex may also drive cognitive pathology. |
2024-08-07 |
2024-08-10 |
mouse |
| Takashi Handa, Qing Zhang, Hidenori Aizaw. Cholinergic modulation of interhemispheric inhibition in the mouse motor cortex. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 7. 2024-07-23. PMID:39042031. |
cholinergic modulation of interhemispheric inhibition in the mouse motor cortex. |
2024-07-23 |
2024-07-25 |
mouse |
| Chao Zhang, R Michael Burge. Cholinergic modulation in the vertebrate auditory pathway. Frontiers in cellular neuroscience. vol 18. 2024-07-04. PMID:38962512. |
in this review, we highlight what is known about cholinergic function throughout the auditory system from the ear to the cortex, but with a particular emphasis on brainstem and midbrain auditory centers. |
2024-07-04 |
2024-07-10 |
Not clear |
| R Oliver Goral, Patricia W Lamb, Jerrel L Yake. Acetylcholine neurons become cholinergic during three time windows in the developing mouse brain. eNeuro. 2024-06-28. PMID:38942474. |
we also found that cholinergic gene expression is initiated in cortical ach interneurons, while the cerebral cortex is innervated by cholinergic projection neurons from the basal forebrain. |
2024-06-28 |
2024-07-01 |
mouse |
| Izabela Jedrasiak-Cape, Chloe Rybicki-Kler, Isla Brooks, Megha Ghosh, Ellen K W Brennan, Sameer Kailasa, Tyler G Ekins, Alan Rupp, Omar J Ahme. Cell-type-specific cholinergic control of granular retrosplenial cortex with implications for angular velocity coding across brain states. bioRxiv : the preprint server for biology. 2024-06-19. PMID:38895393. |
cell-type-specific cholinergic control of granular retrosplenial cortex with implications for angular velocity coding across brain states. |
2024-06-19 |
2024-06-21 |
Not clear |
| Izabela Jedrasiak-Cape, Chloe Rybicki-Kler, Isla Brooks, Megha Ghosh, Ellen K W Brennan, Sameer Kailasa, Tyler G Ekins, Alan Rupp, Omar J Ahme. Cell-type-specific cholinergic control of granular retrosplenial cortex with implications for angular velocity coding across brain states. bioRxiv : the preprint server for biology. 2024-06-19. PMID:38895393. |
lr neurons do not fire persistently in response to cholinergic agonists, in stark contrast to all other principal neuronal subtypes examined within the rsg and across midline cortex. |
2024-06-19 |
2024-06-21 |
Not clear |
| Natasha L Taylor, Christopher J Whyte, Brandon R Munn, Catie Chang, Joseph T Lizier, David A Leopold, Janita N Turchi, Laszlo Zaborszky, Eli J Műller, James M Shin. Causal evidence for cholinergic stabilization of attractor landscape dynamics. Cell reports. vol 43. issue 6. 2024-06-13. PMID:38870015. |
here, we quantify, using data combining local inactivation of the basal forebrain with simultaneous measurement of resting-state fmri activity in the macaque, the causal role of long-range cholinergic input to the stabilization of brain states in the cerebral cortex. |
2024-06-13 |
2024-06-16 |
monkey |
| Fernando R Nodal, Nicholas D Leach, Peter Keating, Johannes C Dahmen, Dylan Zhao, Andrew J King, Victoria M Baj. Neural processing in the primary auditory cortex following cholinergic lesions of the basal forebrain in ferrets. Hearing research. vol 447. 2024-05-11. PMID:38733712. |
neural processing in the primary auditory cortex following cholinergic lesions of the basal forebrain in ferrets. |
2024-05-11 |
2024-05-27 |
Not clear |