| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nathália C B Tortato, Gustavo Ribas, Leonardo A Frizon, Marina Farah, Hélio A G Teive, Renato P Munho. Efficacy of subthalamic deep brain stimulation programming strategies for gait disorders in Parkinson's disease: a systematic review and meta-analysis. Neurosurgical review. vol 47. issue 1. 2024-09-02. PMID:39223361. |
the review identified 36 articles that explored five distinct stn-dbs techniques aimed at addressing gait and postural instability in parkinson's patients: low-frequency stimulation, ventral stn stimulation for simultaneous substantia nigra activation, interleaving, asymmetric stimulation and a short pulse width study. |
2024-09-02 |
2024-09-05 |
Not clear |
| Kurt A Jellinge. The enigma of depression in corticobasal degeneration, a frequent but poorly understood co-morbidity. Journal of neural transmission (Vienna, Austria : 1996). 2024-01-12. PMID:38216704. |
this 4-repeat (4r) tauopathy is morphologically featured by asymmetric frontoparietal atrophy, neuronal loss, and gliosis in cortex and subcortex including substantia nigra, ballooned/achromatic neurons with filamentous 4r tau aggregates in cortex and striatum, widespread thread-like structures, pathognomonic "astroglial plaques", "tufted astrocytes", and numerous "coiled bodies" (in astrocytes and oligodendroglia) in cerebral white matter. |
2024-01-12 |
2024-01-15 |
Not clear |
| Xin Yu Fu, Ying Chun Zhang, Chang Wei Ding, Ping Zhao, Qing Yuan Liu, Min Yang, Cai Shan Wang, Xiao Fang Chen, Ying Zhang, Yu Jing Sheng, Pan Mao, Cheng Jie Mao, Chun Feng Li. Association Between Asymmetry of Substantia Nigra Hyperechogenicity and Clinical Characteristics in Different Parkinson Disease Subtypes: A 5-Year Follow-up Study. Ultrasound in medicine & biology. 2022-08-11. PMID:35953347. |
our study focused on three aspects to determine whether bilateral substantia nigra hyperechogenicity (sn+) is asymmetrical, whether the asymmetry of sn+ is related to the clinical features and whether there is variation in sn+ asymmetry during the progression of parkinson disease (pd). |
2022-08-11 |
2023-08-14 |
human |
| Xin Yu Fu, Ying Chun Zhang, Chang Wei Ding, Ping Zhao, Qing Yuan Liu, Min Yang, Cai Shan Wang, Xiao Fang Chen, Ying Zhang, Yu Jing Sheng, Pan Mao, Cheng Jie Mao, Chun Feng Li. Association Between Asymmetry of Substantia Nigra Hyperechogenicity and Clinical Characteristics in Different Parkinson Disease Subtypes: A 5-Year Follow-up Study. Ultrasound in medicine & biology. 2022-08-11. PMID:35953347. |
association between asymmetry of substantia nigra hyperechogenicity and clinical characteristics in different parkinson disease subtypes: a 5-year follow-up study. |
2022-08-11 |
2023-08-14 |
human |
| Núbia Ribeiro da Conceição, Caroline Ribeiro de Souza, Ávila de Oliveira Júlia, Andrea Cristina de Lima-Pardini, Carla Silva-Batista, Luis Augusto Teixeira, Daniel Boari Coelh. Between-leg asymmetry in automatic postural responses to stance perturbations in people with Parkinson's disease. Gait & posture. vol 97. 2022-07-25. PMID:35872481. |
people with parkinson's disease (pwpd) showed impairments of balance control which can be aggravated by the presence of higher interlateral postural asymmetry caused by a distinct dopaminergic loss in the substantia nigra between cerebral hemispheres. |
2022-07-25 |
2023-08-14 |
Not clear |
| So Tando, Takashi Kasai, Ikuko Mizuta, Hisashi Takahashi, Takeshi Yaoi, Kozo Saito, Tomohito Hojo, Toshiki Mizuno, Masato Hasegawa, Kyoko Ito. An autopsy case of corticobasal syndrome due to asymmetric degeneration of the motor cortex and substantia nigra with TDP-43 proteinopathy, associated with Alzheimer's disease pathology. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 41. issue 3. 2021-11-25. PMID:33537992. |
an autopsy case of corticobasal syndrome due to asymmetric degeneration of the motor cortex and substantia nigra with tdp-43 proteinopathy, associated with alzheimer's disease pathology. |
2021-11-25 |
2023-08-13 |
Not clear |
| So Tando, Takashi Kasai, Ikuko Mizuta, Hisashi Takahashi, Takeshi Yaoi, Kozo Saito, Tomohito Hojo, Toshiki Mizuno, Masato Hasegawa, Kyoko Ito. An autopsy case of corticobasal syndrome due to asymmetric degeneration of the motor cortex and substantia nigra with TDP-43 proteinopathy, associated with Alzheimer's disease pathology. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 41. issue 3. 2021-11-25. PMID:33537992. |
it is highly likely that asymmetric tdp-43 pathology rather than symmetric tau pathology contributed to the laterality of degeneration of the cerebral cortex, substantia nigra, and pyramidal tract, which led us to suggest that tdp-43 proteinopathy might be a primary cause. |
2021-11-25 |
2023-08-13 |
Not clear |
| So Tando, Takashi Kasai, Ikuko Mizuta, Hisashi Takahashi, Takeshi Yaoi, Kozo Saito, Tomohito Hojo, Toshiki Mizuno, Masato Hasegawa, Kyoko Ito. An autopsy case of corticobasal syndrome due to asymmetric degeneration of the motor cortex and substantia nigra with TDP-43 proteinopathy, associated with Alzheimer's disease pathology. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 41. issue 3. 2021-11-25. PMID:33537992. |
we herein report a case of corticobasal syndrome (cbs) due to asymmetric degeneration of the motor cortex and substantia nigra with transactivation response dna-binding protein of 43 kda (tdp-43) proteinopathy, associated with alzheimer's disease (ad) pathology. |
2021-11-25 |
2023-08-13 |
Not clear |
| Hong-Xu Chen, Fu-Chao Liang, Ping Gu, Bian-Ling Xu, Hong-Jun Xu, Wen-Ting Wang, Jia-Yang Hou, Dong-Xiao Xie, Xi-Qing Chai, Sheng-Jun A. Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy. Cell death & disease. vol 11. issue 4. 2021-03-31. PMID:32341347. |
furthermore, exos reached the substantia nigra through the blood-brain barrier (bbb) in vivo, relieved apomorphine-induced asymmetric rotation, reduced substantia nigra dopaminergic neuron loss and apoptosis, and upregulated the level of dopamine in the striatum. |
2021-03-31 |
2023-08-13 |
human |
| I I Coloman, A Sh Chimagomedov. [The influence of motor asymmetry on cognitive functions in Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 120. issue 10. Vyp. 2. 2020-11-20. PMID:33205934. |
this review discusses a possible effect of the asymmetry of substantia nigra lesions on other pd symptoms, primarily neuropsychological functions. |
2020-11-20 |
2023-08-13 |
Not clear |
| I I Coloman, A Sh Chimagomedov. [The influence of motor asymmetry on cognitive functions in Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 120. issue 10. Vyp. 2. 2020-11-20. PMID:33205934. |
the asymmetry of motor symptoms in parkinson's disease (pd) reflects the asymmetry of the degenerative process and death of nigrostriatal dopaminergic neurons in the substantia nigra, which is confirmed by the data of functional neuroimaging. |
2020-11-20 |
2023-08-13 |
Not clear |
| Xiaojun Guan, Tao Guo, Cheng Zhou, Jingjing Wu, Ting Gao, Xueqin Bai, Hongjiang Wei, Yuyao Zhang, Min Xuan, Quanquan Gu, Peiyu Huang, Chunlei Liu, Baorong Zhang, Jiali Pu, Zhe Song, Yaping Yan, Feng Cui, Minming Zhang, Xiaojun X. Asymmetrical nigral iron accumulation in Parkinson's disease with motor asymmetry: an explorative, longitudinal and test-retest study. Aging. vol 12. issue 18. 2020-11-05. PMID:32986011. |
iron accumulation in dominantly and non-dominantly affected substantia nigra (sn) were observed in pd patients with motor asymmetry compared with normal controls (p < 0.005, bonferroni corrected). |
2020-11-05 |
2023-08-13 |
Not clear |
| Antonio Martín-Bastida, Nicholas P Lao-Kaim, Andreas Antonios Roussakis, Graham E Searle, Yue Xing, Roger N Gunn, Stefan T Schwarz, Roger A Barker, Dorothee P Auer, Paola Piccin. Relationship between neuromelanin and dopamine terminals within the Parkinson's nigrostriatal system. Brain : a journal of neurology. vol 142. issue 7. 2020-05-18. PMID:31056699. |
we used a novel approach taking into account the anatomical and functional subdivision of substantia nigra into dorsal and ventral tiers and striatal nuclei into pre- and post-commissural subregions, in accordance with previous animal and post-mortem studies, and consider the clinically asymmetric disease presentation. |
2020-05-18 |
2023-08-13 |
human |
| Ana Carolina Pinheiro Campos, Miriã Benatti Berzuino, Marina Sorrentino Hernandes, Erich Talamoni Fonoff, Rosana Lima Pagan. Monoaminergic regulation of nociceptive circuitry in a Parkinson's disease rat model. Experimental neurology. vol 318. 2020-03-02. PMID:31028827. |
reuptake inhibitors also prevented postural immobility and asymmetric rotational behavior in pd rats without interfering with dopaminergic neuron loss or glial activation in the substantia nigra. |
2020-03-02 |
2023-08-13 |
rat |
| Zheng Zhong, Douglas Merkitch, M Muge Karaman, Jiaxuan Zhang, Yi Sui, Jennifer G Goldman, Xiaohong Joe Zho. High-Spatial-Resolution Diffusion MRI in Parkinson Disease: Lateral Asymmetry of the Substantia Nigra. Radiology. vol 291. issue 1. 2019-12-23. PMID:30777809. |
background motor symptoms in parkinson disease (pd) have exhibited lateral asymmetry, suggesting asymmetric neuronal loss in the substantia nigra (sn). |
2019-12-23 |
2023-08-13 |
human |
| Zheng Zhong, Douglas Merkitch, M Muge Karaman, Jiaxuan Zhang, Yi Sui, Jennifer G Goldman, Xiaohong Joe Zho. High-Spatial-Resolution Diffusion MRI in Parkinson Disease: Lateral Asymmetry of the Substantia Nigra. Radiology. vol 291. issue 1. 2019-12-23. PMID:30777809. |
diffusion mri may be able to help confirm tissue microstructural alterations in the substantia nigra to probe for the presence of asymmetry. |
2019-12-23 |
2023-08-13 |
human |
| Zheng Zhong, Douglas Merkitch, M Muge Karaman, Jiaxuan Zhang, Yi Sui, Jennifer G Goldman, Xiaohong Joe Zho. High-Spatial-Resolution Diffusion MRI in Parkinson Disease: Lateral Asymmetry of the Substantia Nigra. Radiology. vol 291. issue 1. 2019-12-23. PMID:30777809. |
high-spatial-resolution diffusion mri in parkinson disease: lateral asymmetry of the substantia nigra. |
2019-12-23 |
2023-08-13 |
human |
| S. Morgan, D. Baker, J.P. Husto. Relationship between Behavioral Recovery from Unilateral 6-OHDA Lesion of the Substania Nigra and Changes in the Tuberomammillary-Striatal Projection as Measured by HRP-Labelling. Restorative neurology and neuroscience. vol 12. issue 4. 2019-11-20. PMID:12671291. |
a unilateral lesion of dopamine cells in the substantia nigra (sn) results in asymmetrical behavior, and recovery from this asymmetry was previously found to be associated with asymmetrical changes in the nigro-striatal projection as determined by anatomical tracing technique. |
2019-11-20 |
2023-08-12 |
rat |
| S. Morgan, D. Baker, J.P. Husto. Relationship between Behavioral Recovery from Unilateral 6-OHDA Lesion of the Substania Nigra and Changes in the Tuberomammillary-Striatal Projection as Measured by HRP-Labelling. Restorative neurology and neuroscience. vol 12. issue 4. 2019-11-20. PMID:12671291. |
rats had 6-ohda injected into one substantia nigra and were tested for behavioral asymmetry over a 15 day period. |
2019-11-20 |
2023-08-12 |
rat |
| Frauke Knossalla, Zacharias Kohl, Jürgen Winkler, Stefan Schwab, Thomas Schenk, Tobias Engelhorn, Arnd Doerfler, Philipp Gölit. High-resolution diffusion tensor-imaging indicates asymmetric microstructural disorganization within substantia nigra in early Parkinson's disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 50. 2018-07-25. PMID:29366621. |
high-resolution diffusion tensor-imaging indicates asymmetric microstructural disorganization within substantia nigra in early parkinson's disease. |
2018-07-25 |
2023-08-13 |
Not clear |