| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liang Zhao, Hui Ling Qu, Yan Zhang, Xin Wu, Qian Xin Ji, Zhuo Zhang, Dan L. ZL006 mitigates anxiety-like behaviors induced by closed head injury through modulation of the neural circuit from the medial prefrontal cortex to amygdala. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 6. 2024-06-08. PMID:38850218. |
moreover, in the context of attenuating anxiety-like behaviors through zl006 treatment, we observe a reduction in closed head injury-induced astrocyte engulfment, which may correlate with the observed decrease in dendritic spine density of medial prefrontal cortex glutamatergic neurons. |
2024-06-08 |
2024-06-11 |
Not clear |
| Liang Zhao, Hui Ling Qu, Yan Zhang, Xin Wu, Qian Xin Ji, Zhuo Zhang, Dan L. ZL006 mitigates anxiety-like behaviors induced by closed head injury through modulation of the neural circuit from the medial prefrontal cortex to amygdala. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 6. 2024-06-08. PMID:38850218. |
additionally, zl006 administration effectively mitigates astrocyte activation, leading to the restoration of medial prefrontal cortex glutamatergic neuron activity. |
2024-06-08 |
2024-06-11 |
Not clear |
| Yi-Wen Fu, Shi-Yang Jin, Jing-Ting Li, Xiao-Wen Li, Tian-Ming Gao, Jian-Ming Yan. Mature astrocytes as source for astrocyte repopulation after deletion in the medial prefrontal cortex: Implications for depression. Glia. 2024-05-27. PMID:38801194. |
mature astrocytes as source for astrocyte repopulation after deletion in the medial prefrontal cortex: implications for depression. |
2024-05-27 |
2024-05-31 |
mouse |
| Armani P Del Franco, Eric A Newma. Astrocyte β-adrenergic receptor activity regulates NMDA receptor signaling of medial prefrontal cortex pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-11-21. PMID:37989594. |
we monitored changes to astrocyte process volume in response to noradrenergic agonists in the medial prefrontal cortex of male and female mice. |
2023-11-21 |
2023-11-29 |
mouse |
| Armani P Del Franco, Eric A Newma. Astrocyte β-adrenergic receptor activity regulates NMDA receptor signaling of medial prefrontal cortex pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-11-21. PMID:37989594. |
astrocyte β-adrenergic receptor activity regulates nmda receptor signaling of medial prefrontal cortex pyramidal neurons. |
2023-11-21 |
2023-11-29 |
mouse |
| Su-Ju Eo, Yea-Hyun Lee. Effects of exercise intensity on the reactive astrocyte polarization in the medial prefrontal cortex. Physical activity and nutrition. vol 27. issue 2. 2023-08-16. PMID:37583068. |
effects of exercise intensity on the reactive astrocyte polarization in the medial prefrontal cortex. |
2023-08-16 |
2023-09-07 |
Not clear |
| Su-Ju Eo, Yea-Hyun Lee. Effects of exercise intensity on the reactive astrocyte polarization in the medial prefrontal cortex. Physical activity and nutrition. vol 27. issue 2. 2023-08-16. PMID:37583068. |
this study aimed to determine whether astrocyte polarization and synaptic alterations in the medial prefrontal cortex (mpfc) are affected differently by high- and moderate-intensity exercise. |
2023-08-16 |
2023-09-07 |
Not clear |
| b' Karol\\xc3\\xadna Bretov\\xc3\\xa1, Viktorie Svobodov\\xc3\\xa1, Petr Dubov\\xc3\\xb. Astrocyte reactivity in the glia limitans superficialis of the rat medial prefrontal cortex following sciatic nerve injury. Histochemistry and cell biology. 2022-11-03. PMID:36326875.' |
astrocyte reactivity in the glia limitans superficialis of the rat medial prefrontal cortex following sciatic nerve injury. |
2022-11-03 |
2023-08-14 |
rat |
| b' Karol\\xc3\\xadna Bretov\\xc3\\xa1, Viktorie Svobodov\\xc3\\xa1, Petr Dubov\\xc3\\xb. Astrocyte reactivity in the glia limitans superficialis of the rat medial prefrontal cortex following sciatic nerve injury. Histochemistry and cell biology. 2022-11-03. PMID:36326875.' |
many studies have observed astrocyte reactivity in the medial prefrontal cortex (mpfc) parenchyma induced by a peripheral nerve injury, while the response of gls astrocytes is still not fully understood. |
2022-11-03 |
2023-08-14 |
rat |
| Jie Chen, Sumei Liu, Xueqin Wang, Jufang Huang, Jade Phillips, Daqing Ma, Wen Ouyang, Jianbin Ton. HDAC6 Inhibition Alleviates Anesthesia and Surgery-Induced Less Medial Prefrontal-Dorsal Hippocampus Connectivity and Cognitive Impairment in Aged Rats. Molecular neurobiology. 2022-07-26. PMID:35882756. |
local hdac6 knockdown and systemic hdac6 inhibition both increased bda-positive neurons number of medial prefrontal cortex, alleviated learning and memory impairment in the barnes maze task and water maze task, decreased hdac6 expression, inflammatory cytokines, astrocyte and microglial activation, and increased ac-tubulin expression in aged rats which received surgery. |
2022-07-26 |
2023-08-14 |
rat |
| Gang Yu, Feng Cao, Tingting Hou, Yunsheng Cheng, Benli Jia, Liang Yu, Wanjing Chen, Yanyan Xu, Mingming Chen, Yong Wan. Astrocyte reactivation in medial prefrontal cortex contributes to obesity-promoted depressive-like behaviors. Journal of neuroinflammation. vol 19. issue 1. 2022-06-27. PMID:35761401. |
astrocyte reactivation in medial prefrontal cortex contributes to obesity-promoted depressive-like behaviors. |
2022-06-27 |
2023-08-14 |
mouse |
| Troy D Fort, Mary E Cai. The Role of Astroglial xCT in Mitigating Cue-Induced Amphetamine-Seeking. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555299. |
following testing, all rats were perfused and brains were extracted for immunofluorescence (if) analysis of astrocyte and xct transporter expression within the acb and medial prefrontal cortex using a simultaneous immunofluorescence (if) method. |
2022-05-13 |
2023-08-13 |
rat |
| Pamela Reyes-Ortega, María Berenice Soria-Ortiz, Verónica M Rodríguez, Eva Olivia Vázquez-Martínez, Mauricio Díaz-Muñoz, Daniel Reyes-Har. Anorexia disrupts glutamate-glutamine homeostasis associated with astrocytes in the prefrontal cortex of young female rats. Behavioural brain research. 2021-12-15. PMID:34906609. |
anorexia reduced the astrocyte density, promoted a de-ramified morphology, and augmented the de-ramified/ramified astrocyte ratio in the medial prefrontal cortex and orbitofrontal cortex, but not in the motor cortex (m2). |
2021-12-15 |
2023-08-13 |
rat |
| Matthew M Hurley, Sarah C Collica, S Andrew Aston, Lucas J Wiles, Raphael C Weiner, Aditi Biswas, Harshit Bhasin, Aliasgher I Sabir, Ethan J Goodman, Ritika Purbey, Kellie L K Tamashiro, Timothy H Mora. Adolescent female rats prone to the activity based anorexia (ABA) paradigm have altered hedonic responses and cortical astrocyte density compared to resistant animals. Appetite. vol 168. 2021-12-11. PMID:34461195. |
measures of food intake, running wheel activity, taste reactivity and medial prefrontal cortex astrocyte expression were compared across groups. |
2021-12-11 |
2023-08-13 |
rat |
| Wei Yao, Qianqian Cao, Shilin Luo, Lujuan He, Chun Yang, Jiaxu Chen, Qi Qi, Kenji Hashimoto, Ji-Chun Zhan. Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine. Molecular psychiatry. 2021-12-10. PMID:34819637. |
nrbp1 was localized in the microglia and neuron, not astrocyte, of mouse medial prefrontal cortex (mpfc). |
2021-12-10 |
2023-08-13 |
mouse |
| Rong Cao, Lin Li, Wen Zhang, Jun Lu, Yu Wang, Qian Chen, Wentong Zhang, Mingming Chen, Liang Sheng, Keshu Cai, Guangxu X. Melatonin attenuates repeated mild traumatic brain injury-induced cognitive deficits by inhibiting astrocyte reactivation. Biochemical and biophysical research communications. vol 580. 2021-10-19. PMID:34607259. |
additionally, we observed a significant increase in neuronal activity and inhibition of astrocyte reactivation in medial prefrontal cortex and hippocampus, but not in other cognitive deficit related brain regions. |
2021-10-19 |
2023-08-13 |
mouse |
| Blanca Diaz-Castro, Alexander M Bernstein, Giovanni Coppola, Michael V Sofroniew, Baljit S Khak. Molecular and functional properties of cortical astrocytes during peripherally induced neuroinflammation. Cell reports. vol 36. issue 6. 2021-09-07. PMID:34380036. |
we assess medial prefrontal cortex (pfc) and visual cortex (vcx) astrocyte and whole-tissue gene expression changes in mice following peripherally induced neuroinflammation triggered by a systemic bacterial endotoxin, lipopolysaccharide, which produces sickness-related behaviors, including anhedonia. |
2021-09-07 |
2023-08-13 |
mouse |
| Anze Testen, Marian T Sepulveda-Orengo, Christiann H Gaines, Kathryn J Reissne. Region-Specific Reductions in Morphometric Properties and Synaptic Colocalization of Astrocytes Following Cocaine Self-Administration and Extinction. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30147645. |
in the current study, we have extended our assessment of the effects of cocaine self-administration on morphometric properties and synaptic colocalization of astrocyte peripheral processes in the prelimbic region of the medial prefrontal cortex (pl) and basolateral nucleus of the amygdala (bla), both known to also contribute significantly to motivated behaviors. |
2020-09-30 |
2023-08-13 |
rat |
| Felipe V Gomes, Ricardo Llorente, Elaine A Del Bel, Maria-Paz Viveros, Meritxell López-Gallardo, Francisco S Guimarãe. Decreased glial reactivity could be involved in the antipsychotic-like effect of cannabidiol. Schizophrenia research. vol 164. issue 1-3. 2016-03-28. PMID:25680767. |
we also evaluated changes in neun (a neuronal marker), iba-1 (a microglia marker) and gfap (an astrocyte marker) expression in the medial prefrontal cortex (mpfc), dorsal striatum, nucleus accumbens core and shell, and dorsal hippocampus by immunohistochemistry. |
2016-03-28 |
2023-08-13 |
Not clear |
| Yaveth Ruvalcaba-Delgadillo, Sonia Luquín, Rodrigo Ramos-Zúñiga, Alfredo Feria-Velasco, Rocío Elizabeth González-Castañeda, Maria Isabel Pérez-Vega, Fernando Jáuregui-Huerta, Joaquín García-Estrad. Early-life exposure to noise reduces mPFC astrocyte numbers and T-maze alternation/discrimination task performance in adult male rats. Noise & health. vol 17. issue 77. 2015-09-15. PMID:26168952. |
in this experiment, we evaluated the long-term effects of noise by assessing both astrocyte changes in medial prefrontal cortex (mpfc) and mpfc-related alternation/discrimination tasks. |
2015-09-15 |
2023-08-13 |
human |