| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bo Pang, Ting Ca. Hesperidin produces antidepressant effects by activating AMPA receptor: enhancing synaptic proteins to promote hippocampal neuronal activities. Behavioural pharmacology. 2024-11-29. PMID:39611623. |
hesperidin produces antidepressant effects by activating ampa receptor: enhancing synaptic proteins to promote hippocampal neuronal activities. |
2024-11-29 |
2024-12-01 |
mouse |
| Bo Pang, Ting Ca. Hesperidin produces antidepressant effects by activating AMPA receptor: enhancing synaptic proteins to promote hippocampal neuronal activities. Behavioural pharmacology. 2024-11-29. PMID:39611623. |
this study shows that hesperidin exerts its antidepressant effects by activating α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (ampa) receptor to promote synaptic and neuronal function in the hippocampus. |
2024-11-29 |
2024-12-01 |
mouse |
| Bo Pang, Ting Ca. Hesperidin produces antidepressant effects by activating AMPA receptor: enhancing synaptic proteins to promote hippocampal neuronal activities. Behavioural pharmacology. 2024-11-29. PMID:39611623. |
in addition, hesperidin increased the expression of ampa receptor protein (glur1) and synaptic proteins (bdnf, psd95, synapsin1) in the hippocampus of cums-exposed mice. |
2024-11-29 |
2024-12-01 |
mouse |
| Bo Pang, Ting Ca. Hesperidin produces antidepressant effects by activating AMPA receptor: enhancing synaptic proteins to promote hippocampal neuronal activities. Behavioural pharmacology. 2024-11-29. PMID:39611623. |
furthermore, inhibition of ampa receptor activity by nbqx blocked the effect of hesperidin in reversing the depressive phenotypes, upregulated the expression of synaptic proteins (bdnf, psd95, synapsin1) and cfos-positive cells in the hippocampus, and increased the number of ki67-positive cells in the dentate gyrus of the hippocampus of cums-exposed mice. |
2024-11-29 |
2024-12-01 |
mouse |
| Yehee Lee, Jieun Jeon, So-Ri Son, Eunbi Cho, Somin Moon, A Young Park, Hye Ji Chae, Ho Jung Bae, Minho Moon, Se Jin Jeon, Dae Sik Jang, Dong Hyun Ki. 3,4,5-trimethoxycinnamic acid methyl ester isolated from Polygala tenuifolia enhances hippocampal LTP through PKA and calcium-permeable AMPA receptor. Biochemical pharmacology. 2024-11-14. PMID:39542183. |
3,4,5-trimethoxycinnamic acid methyl ester isolated from polygala tenuifolia enhances hippocampal ltp through pka and calcium-permeable ampa receptor. |
2024-11-14 |
2024-11-17 |
mouse |
| Megumi Ikegami, Hiroko Iked. Hyperfunction of AMPA receptors in the amygdala and hippocampus contributes to enhanced fear memory in diabetic mice. Brain research. 2024-11-11. PMID:39528093. |
hyperfunction of ampa receptors in the amygdala and hippocampus contributes to enhanced fear memory in diabetic mice. |
2024-11-11 |
2024-11-17 |
mouse |
| Megumi Ikegami, Hiroko Iked. Hyperfunction of AMPA receptors in the amygdala and hippocampus contributes to enhanced fear memory in diabetic mice. Brain research. 2024-11-11. PMID:39528093. |
the present study investigated whether functions of ampa receptors in the amygdala and hippocampus are altered in streptozotocin (stz)-induced diabetic mice. |
2024-11-11 |
2024-11-17 |
mouse |
| Megumi Ikegami, Hiroko Iked. Hyperfunction of AMPA receptors in the amygdala and hippocampus contributes to enhanced fear memory in diabetic mice. Brain research. 2024-11-11. PMID:39528093. |
while protein levels of the glua1 subunit of ampa receptors were not altered in the amygdala and hippocampus, protein levels of glua1 phosphorylated at serine 845 in the amygdala and hippocampus and of glua1 phosphorylated at serine 831 in the hippocampus were increased in stz-induced diabetic mice. |
2024-11-11 |
2024-11-17 |
mouse |
| Megumi Ikegami, Hiroko Iked. Hyperfunction of AMPA receptors in the amygdala and hippocampus contributes to enhanced fear memory in diabetic mice. Brain research. 2024-11-11. PMID:39528093. |
these results indicate that the functions of ampa receptors in the amygdala and hippocampus are enhanced due to increased phosphorylation by pka and camkii, which enhances fear memory in diabetic mice. |
2024-11-11 |
2024-11-17 |
mouse |
| Jesús Chávez-Reyes, Carlos H López-Lariz, M Aisha Acosta-Cruz, Bruno A Marichal-Cancin. Acute glyphosate and aminomethylphosphonic acid (AMPA), its major metabolite, impaired spatial orientation, navigation, learning and/or memory in female rats. Behavioural brain research. 2024-11-10. PMID:39522773. |
previous preclinical reports suggest that acute intoxication with ampa and glyphosate exerts decrease on hippocampal acetylcholinesterase activity and produces more metabolomic alterations in the female brain over the male one. |
2024-11-10 |
2024-11-17 |
human |
| Olga Vladimirovna Nadei, Natalia Ivanovna Agalakov. AMPA and NMDA Receptors in Hippocampus of Rats with Fluoride-Induced Cognitive Decline. International journal of molecular sciences. vol 25. issue 21. 2024-11-09. PMID:39519348. |
ampa and nmda receptors in hippocampus of rats with fluoride-induced cognitive decline. |
2024-11-09 |
2024-11-17 |
rat |
| Olga Vladimirovna Nadei, Natalia Ivanovna Agalakov. AMPA and NMDA Receptors in Hippocampus of Rats with Fluoride-Induced Cognitive Decline. International journal of molecular sciences. vol 25. issue 21. 2024-11-09. PMID:39519348. |
this experimental study was performed to evaluate the alterations in the expression of a few subunits composing glutamate ampa (a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) and nmda (n-methyl-d-aspartate) receptors in the hippocampal cells of wistar rats in response to long-term fluoride (f |
2024-11-09 |
2024-11-17 |
rat |
| Lorenzo Curti, Beatrice Rizzi, Francesca Mottarlini, Elisabetta Bigagli, Alice Ilari, Alessia Costa, Virginia Sordi, Giuseppe Ranieri, Cristina Luceri, Nazzareno Cannella, Massimo Ubaldi, Alessio Masi, Fabio Fumagalli, Lucia Caffino, Guido Mannaioni, Elisabetta Gerac. Prenatal ethanol exposure impairs hippocampal plasticity and cognition in adolescent mice. Progress in neuro-psychopharmacology & biological psychiatry. 2024-10-24. PMID:39447689. |
we have recently found that chronic ethanol (etoh) exposure decreases ampa-mediated neurotransmission and expression through the overexpression of the specific microrna (mir)137 and 501-3p, which target glua1 ampa subunit, in the developing hippocampus in vitro. |
2024-10-24 |
2024-10-28 |
mouse |
| Min Jia, Gui-Zhou Li, Jiang Chen, Xiao-Hui Tang, Yan-Yu Zang, Guo-Lin Yang, Yun Stone Shi, Daqing Ma, Mu-Huo Ji, Jian-Jun Yan. Hippocampal Nogo66-NgR1 signaling activation restricts postsynaptic assembly in aged mice with postoperative neurocognitive disorders. Aging cell. 2024-10-16. PMID:39412367. |
additionally, these changes hindered the efficient postsynaptic delivery of the subunit glua1 and glua2 of ampa receptors (ampars), consequently diminishing excitatory neurotransmission in the hippocampus. |
2024-10-16 |
2024-10-18 |
mouse |
| Min Jia, Gui-Zhou Li, Jiang Chen, Xiao-Hui Tang, Yan-Yu Zang, Guo-Lin Yang, Yun Stone Shi, Daqing Ma, Mu-Huo Ji, Jian-Jun Yan. Hippocampal Nogo66-NgR1 signaling activation restricts postsynaptic assembly in aged mice with postoperative neurocognitive disorders. Aging cell. 2024-10-16. PMID:39412367. |
our work indicates that high hippocampal nogo66-ngr1 signaling disrupts postsynaptic ampa receptor surface delivery due to f-actin depolymerization in the pathophysiology of pncd. |
2024-10-16 |
2024-10-18 |
mouse |
| Misaki Morishita, Shinji Matsud. SARM1 is essential for NMDA receptor-dependent endocytosis of AMPA receptors in hippocampal neurons. Neuroscience research. 2024-09-30. PMID:39349221. |
sarm1 is essential for nmda receptor-dependent endocytosis of ampa receptors in hippocampal neurons. |
2024-09-30 |
2024-10-03 |
Not clear |
| Misaki Morishita, Shinji Matsud. SARM1 is essential for NMDA receptor-dependent endocytosis of AMPA receptors in hippocampal neurons. Neuroscience research. 2024-09-30. PMID:39349221. |
in this study, we showed that small interfering rna (sirna)-mediated knockdown of sterile alpha and toll/interleukin receptor motif containing 1 (sarm1) in cultured hippocampal neurons prevented the n-methyl-d-aspartate (nmda)-induced reduction in cell surface ampa receptors. |
2024-09-30 |
2024-10-03 |
Not clear |
| Misaki Morishita, Shinji Matsud. SARM1 is essential for NMDA receptor-dependent endocytosis of AMPA receptors in hippocampal neurons. Neuroscience research. 2024-09-30. PMID:39349221. |
these results suggest that both the mitochondrial localization and nadase activity of sarm1 are essential for nmda receptor-dependent ampa receptor internalization in the hippocampal neurons. |
2024-09-30 |
2024-10-03 |
Not clear |
| Bruna Teixeira-Silva, Giovanna Varzea Roberti Monteiro de Mattos, Vinicius de Frias Carvalho, Paula Campello-Cost. Caffeine intake during lactation has a sex-dependent effect on the hippocampal excitatory/inhibitory balance and pups' behavior. Brain research. 2024-09-20. PMID:39304106. |
we found that maternal caffeine intake significantly reduced glun1 subunits of the nmda receptor, increased the glua1/glua2 ratio of ampa receptor in the dorsal hippocampus, and decreased gad content in female pups' ventral hippocampus. |
2024-09-20 |
2024-09-23 |
rat |
| Vartika Gupta, S Prasa. Differential Alterations in the Expression of AMPA Receptor and Its Trafficking Proteins in the Hippocampus Are Associated with Recognition Memory Impairment in the Rotenone-Parkinson's Disease Mouse Model: Neuroprotective Role of Bacopa monnieri Extract CDRI 08. Molecular neurobiology. 2024-07-29. PMID:39073529. |
differential alterations in the expression of ampa receptor and its trafficking proteins in the hippocampus are associated with recognition memory impairment in the rotenone-parkinson's disease mouse model: neuroprotective role of bacopa monnieri extract cdri 08. |
2024-07-29 |
2024-08-02 |
mouse |