All Relations between Trazodone and Mirtazapine

Publication Sentence Publish Date Extraction Date Species
Magdalena Świądro-Piętoń, Dominika Dudek, Renata Wietecha-Posłuszn. Direct Immersion-Solid Phase Microextraction for Therapeutic Drug Monitoring of Patients with Mood Disorders. Molecules (Basel, Switzerland). vol 29. issue 3. 2024-02-10. PMID:38338419. it has been adapted to identify the most commonly used drugs in mood disorders, including amitriptyline, citalopram, fluoxetine, paroxetine, sertraline, trazodone, duloxetine, venlafaxine, lamotrigine, quetiapine, olanzapine, and mirtazapine. 2024-02-10 2024-02-12 Not clear
Antoine Boustany, Somtochukwu Onwuzo, Hadi Khaled Abou Zeid, Ashraf Almomani, Imad Asaa. ANTIDEPRESSANT MEDICATIONS ARE ASSOCIATED WITH INCREASED RISK OF HOSPITAL-ACQUIRED CLOSTRIDIOIDES DIFFICILE INFECTION: A POPULATION-BASED STUDY. Arquivos de gastroenterologia. vol 60. issue 3. 2023-10-04. PMID:37792759. conclusion - in contrary to fluoxetine; mirtazapine, nortriptyline, and trazodone were associated with increased risk of cdi in hospitalized patients. 2023-10-04 2023-10-07 Not clear
Antoine Boustany, Somtochukwu Onwuzo, Hadi Khaled Abou Zeid, Ashraf Almomani, Imad Asaa. ANTIDEPRESSANT MEDICATIONS ARE ASSOCIATED WITH INCREASED RISK OF HOSPITAL-ACQUIRED CLOSTRIDIOIDES DIFFICILE INFECTION: A POPULATION-BASED STUDY. Arquivos de gastroenterologia. vol 60. issue 3. 2023-10-04. PMID:37792759. results - the risk of cdi in hospitalized patients was increased in individuals diagnosed with inflammatory bowel disease (or: 4.44; 95%ci: 4.35-4.52), and in patients using clindamycin (or: 1.55; 95%ci: 1.53-1.57), beta-lactam antibiotics (or: 1.62; 95%ci: 1.60-1.64), ppi (or: 3.27; 95%ci: 3.23-3.30), trazodone (or: 1.31; 95%ci: 1.29-1.33), nortriptyline (or: 1.25; 95%ci: 1.21-1.28), and mirtazapine (or: 2.50; 95%ci: 2.46-2.54). 2023-10-04 2023-10-07 Not clear
Roland Grad, Mark H Ebel. Top 20 Research Studies of 2022 for Primary Care Physicians. American family physician. vol 107. issue 4. 2023-04-13. PMID:37054418. combination therapy using a selective serotonin reuptake inhibitor, serotonin-norepinephrine reuptake inhibitor, or tricyclic antidepressant with mirtazapine or trazodone is more effective than monotherapy for first-line treatment of acute severe depression and when monotherapy fails. 2023-04-13 2023-08-14 Not clear
Faruk Ugu. The Relationship Between Maternal Antidepressants and Neonatal Hypoglycemia: A Systematic Review. Alpha psychiatry. vol 22. issue 5. 2022-11-30. PMID:36447450. the searched keywords were as follows: antidepressants, pregnancy, selective serotonin reuptake inhibitors (ssris), citalopram, fluoxetine, paroxetine, escitalopram, sertraline, fluvoxamine, selective serotonin-norepinephrine reuptake inhibitors (snris), venlafaxine, tricyclic antidepressants (tcas), neonatal outcomes, neonatal hypoglycemia, imipramine, clomipramine, amitriptyline, bupropion, trazodone, and mirtazapine. 2022-11-30 2023-08-14 Not clear
S Schreiber, C G Pic. Trazodone and mirtazapine: A possible opioid involvement in their use (at low dose) for sleep? Medical hypotheses. vol 136. 2021-01-25. PMID:31759303. summing up the various interactions of trazodone and mirtazapine with opioid, noradrenergic and serotonergic agonists and antagonists, we found that the antinociceptive effect of trazodone is influenced by the opioid receptor subtypes mu and delta (and a clear 5-ht mechanism of antinociception), while the antinociceptive effect of mirtazapine is mainly influenced by kappa and mu opioid receptor subtype (combined with both serotonergic and noradrenergic receptors). 2021-01-25 2023-08-13 mouse
S Schreiber, C G Pic. Trazodone and mirtazapine: A possible opioid involvement in their use (at low dose) for sleep? Medical hypotheses. vol 136. 2021-01-25. PMID:31759303. the mostly prescribed antidepressants for sleep are trazodone (a weak, but specific inhibitor of the synaptosomal uptake of serotonin, that also binds to alpha-1 and alpha-2 adrenoreceptor sites) and mirtazapine (a postsynaptic drug which enhances noradrenergic and 5-ht1a-mediated serotonergic neurotransmission via antagonism of central alpha-2-auto- and hetero-adrenoreceptors). 2021-01-25 2023-08-13 mouse
Hui-Ting Yang, Yu-Wen Liu, Shin-Chang Kuo, Chun-Yen Chen, Yi-Wei Ye. Repeated Leg Edema Induced by Trazodone and Mirtazapine in a Patient With Depression With Successful Agomelatine Substitution: A Case Report. American journal of therapeutics. 2020-10-06. PMID:33021530. repeated leg edema induced by trazodone and mirtazapine in a patient with depression with successful agomelatine substitution: a case report. 2020-10-06 2023-08-13 Not clear
Rui Lopes, José Carlos Alves, Raquel Garcia Reg. Trazodone Addition to Paroxetine and Mirtazapine in a Patient with Treatment-Resistant Depression: The Pros and Cons of Combining Three Antidepressants. Case reports in medicine. vol 2016. 2020-10-01. PMID:27807450. we report a relapse of moderate-to-severe depressive symptoms with insomnia that successfully remitted after the addition of trazodone to a dual combination of paroxetine and mirtazapine (in standard effective doses) in a patient with treatment-resistant depression. 2020-10-01 2023-08-13 Not clear
Rui Lopes, José Carlos Alves, Raquel Garcia Reg. Trazodone Addition to Paroxetine and Mirtazapine in a Patient with Treatment-Resistant Depression: The Pros and Cons of Combining Three Antidepressants. Case reports in medicine. vol 2016. 2020-10-01. PMID:27807450. trazodone addition to paroxetine and mirtazapine in a patient with treatment-resistant depression: the pros and cons of combining three antidepressants. 2020-10-01 2023-08-13 Not clear
Gustavo Santos, Ana Maria Moreir. Distressing Visual Hallucinations after Treatment with Trazodone. Case reports in psychiatry. vol 2017. 2020-10-01. PMID:28702268. trazodone was discontinued, leading to a complete resolution of his visual hallucinations, and he was treated with mirtazapine for 6 months. 2020-10-01 2023-08-13 Not clear
Junichi Mukai, Saki Maruyama, Katsuya Otori, Rie Kubot. [Antidepressant Medication Use and Development of Hyperglycemia and Diabetes Mellitus: A Japanese Adverse Drug Event Report Database Study]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 140. issue 4. 2020-09-07. PMID:32238642. the lower limit of 95%ci of rors for 13 antidepressants (imipramine, clomipramine, nortriptyline, amitriptyline, amoxapine, maprotiline, mianserin, sertraline, paroxetine, escitalopram, duloxetine, mirtazapine, and trazodone), which included all subclasses, exceeded 1. 2020-09-07 2023-08-13 Not clear
T E Schwasinger-Schmidt, M Macalus. Other Antidepressants. Handbook of experimental pharmacology. vol 250. 2019-07-22. PMID:30194544. this chapter addresses the following fda-approved medications for the treatment of major depressive disorder available for use in the united states including bupropion, mirtazapine, trazodone, vortioxetine, and vilazodone. 2019-07-22 2023-08-13 Not clear
Vincent Chin-Hung Chen, Chiao-Fan Lin, Yi-Hsuan Hsieh, Hsin-Yi Liang, Kuo-You Huang, Wei-Che Chiu, Yena Lee, Roger S McIntyre, Hsiang-Lin Cha. Hepatocellular carcinoma and antidepressants: a nationwide population-based study. Oncotarget. vol 8. issue 18. 2018-03-05. PMID:27783998. no apparent association was found between use of other classes of antidepressants and hcc, including monoamine oxidase inhibitors (maois), serotonin norepinephrine reuptake inhibitors (snris), trazodone, mirtazapine and bupropion. 2018-03-05 2023-08-13 Not clear
André F Carvalho, Manu S Sharma, André R Brunoni, Eduard Vieta, Giovanni A Fav. The Safety, Tolerability and Risks Associated with the Use of Newer Generation Antidepressant Drugs: A Critical Review of the Literature. Psychotherapy and psychosomatics. vol 85. issue 5. 2017-07-13. PMID:27508501. in this critical review, we evaluated the literature on adverse events, tolerability and safety of selective serotonin reuptake inhibitors, serotonin noradrenaline reuptake inhibitors, bupropion, mirtazapine, trazodone, agomelatine, vilazodone, levomilnacipran and vortioxetine. 2017-07-13 2023-08-13 Not clear
Diána Kostyalik, Zita Kátai, Szilvia Vas, Dorottya Pap, Péter Petschner, Eszter Molnár, István Gyertyán, Lajos Kalmár, László Tóthfalusi, Gyorgy Bagd. Chronic escitalopram treatment caused dissociative adaptation in serotonin (5-HT) 2C receptor antagonist-induced effects in REM sleep, wake and theta wave activity. Experimental brain research. vol 232. issue 3. 2014-10-14. PMID:24395141. agomelatine, trazodone, nefazodone, amitriptyline, mirtazapine, mianserin, fluoxetine) or most atypical antipsychotics, have 5-hydroxytryptamine 2c (5-ht2c) receptor-blocking property. 2014-10-14 2023-08-12 rat
Joanna Mika, Magdalena Zychowska, Wioletta Makuch, Ewelina Rojewska, Barbara Przewlock. Neuronal and immunological basis of action of antidepressants in chronic pain - clinical and experimental studies. Pharmacological reports : PR. vol 65. issue 6. 2014-10-14. PMID:24553009. these new drugs that are effective for chronic pain belong to the tetracyclic antidepressants (tecas) group (amoxapine, maprotiline), the serotonin and noradrenaline reuptake inhibitors (snris) group (duloxetine, venlafaxine, milnacipran) and the atypical antidepressants group (bupropion, trazodone, mirtazapine, nefazodone). 2014-10-14 2023-08-12 Not clear
Stephen M Stahl, Clara Lee-Zimmerman, Sylvia Cartwright, Debbi Ann Morrissett. Serotonergic drugs for depression and beyond. Current drug targets. vol 14. issue 5. 2013-10-29. PMID:23531115. the original trend to do this selectively (e.g., with ssris or selective serotonin reuptake inhibitors) has given way to combining various additional pharmacologic mechanisms with sert inhibition, including dual actions by single drugs (e.g., snris or serotonin norepinephrine reuptake inhibitors), or by augmenting ssris with a second drug of a different mechanism (e.g., bupropion with dopamine and norepinephrine reuptake inhibition; trazodone with 5ht2a antagonism; mirtazapine with 5ht2a/5ht2c/5ht3/alpha2 antagonism; buspirone or some atypical antipsychotics with 5ht1a partial agonism; other atypical antipsychotics with 5ht2c/5ht7 antagonism and other mechanisms). 2013-10-29 2023-08-12 Not clear
Ripu D Jinda. Insomnia in patients with depression: some pathophysiological and treatment considerations. CNS drugs. vol 23. issue 4. 2009-07-23. PMID:19374460. one approach to the management of insomnia associated with depression is to choose a sedating antidepressant agent such as trazodone, mirtazapine or agomelatine. 2009-07-23 2023-08-12 Not clear
Wit Dubarek, Krzysztof Kuci. [Applications and safety of modern antidepressants in patients with liver diseases]. Wiadomosci lekarskie (Warsaw, Poland : 1960). vol 60. issue 1-2. 2007-08-24. PMID:17607965. in the study we subjected to analysis literature referred to safety of ssri's, venlafaxine, milnacipran, mirtazapine, nefazodone and trazodone in patients with the diagnosis of depression and concomitant hepatopathy. 2007-08-24 2023-08-12 Not clear