| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Manabu Takano, Tsuyoshi Okada, Katsutoshi Shioda, Chikara Yonekawa, Shiro Sud. Risperidone suppresses caffeine-induced hyperthermia and hyperactivity in rats. Neuroscience letters. 2024-09-02. PMID:39222834. |
the rats received intraperitoneal injections of saline, risperidone (0.25 mg/kg, 0.5 mg/kg), way-100635, ketanserin, haloperidol, sulpiride, or sch 23390, 5 min after the administration of caffeine (25 mg/kg). |
2024-09-02 |
2024-09-05 |
rat |
| Bálint Jezsó, Sára Kálmán, Kiara Gitta Farkas, Edit Hathy, Katalin Vincze, Dzsenifer Kovács-Schoblocher, Julianna Lilienberg, Csongor Tordai, Zsófia Nemoda, László Homolya, Ágota Apáti, János M Réthely. Haloperidol, Olanzapine, and Risperidone Induce Morphological Changes in an In Vitro Model of Human Hippocampal Neurogenesis. Biomolecules. vol 14. issue 6. 2024-06-27. PMID:38927091. |
haloperidol, olanzapine, and risperidone induce morphological changes in an in vitro model of human hippocampal neurogenesis. |
2024-06-27 |
2024-06-29 |
human |
| Gabrielle Cataford, Laurie-Anne Monton, Stephanie Karzon, Camille Livernoche-Leduc, Mar Saavedra-Mitjans, Marie-Julie Potvin, Francis Bernard, Lisa Burry, Caroline Arbour, David R Williamso. Cognitive and Motor Function Effects of Antipsychotics in Traumatic Brain Injury: A Systematic Review of Pre-Clinical Studies. Neurotrauma reports. vol 5. issue 1. 2024-03-11. PMID:38463417. |
the analysis revealed no consistent effect of haloperidol on motor functions, but risperidone was associated with a significant impairment in motor function on day 5 post-injury (7.05 sec; 95% confidence interval [ci]: 1.47, 12.62; i |
2024-03-11 |
2024-03-14 |
rat |
| Dario Conti, Nicolaja Girone, Maria Boscacci, Lorenzo Casati, Niccolò Cassina, Lucia Cerolini, Luca Giacovelli, Caterina Viganò, Marian Mora Conde, Laura Cremaschi, Bernardo M Dell'Oss. The use of antipsychotics in obsessive compulsive disorder. Human psychopharmacology. 2024-02-10. PMID:38340275. |
risperidone, aripiprazole, and haloperidol seem to be the most useful medications, whereas 'first generation' antipsychotics may be indicated in case of comorbidity with tics and/or tourette syndrome. |
2024-02-10 |
2024-02-14 |
Not clear |
| Mingwei Gao, Fuqi Wang, Chuanyao Sun, Shuzhuo Zhang, Ruibin S. Effects of olanzapine on hippocampal CA3 and the prefrontal cortex local field potentials. European journal of pharmacology. 2024-02-07. PMID:38325793. |
olanzapine is an antipsychotic drug applied in psychiatry to treat psychoses, especially schizophrenia and schizoaffective disorders with similar or better improvement than haloperidol and risperidone in the treatment of depressive and negative symptoms. |
2024-02-07 |
2024-02-10 |
Not clear |
| Sakiko Hirofuji, Koumi Miyasaka, Mika Maezawa, Wataru Wakabayashi, Keita Oura, Satoshi Nakao, Nanaka Ichihara, Yuka Nokura, Moe Yamashita, Kensuke Matsui, Hideyuki Tanaka, Mayuko Masuta, Ichiro Ieiri, Kazuhiro Iguchi, Mitsuhiro Nakamur. Evaluation of neuroleptic malignant syndrome induced by antipsychotic drugs using spontaneous reporting system. Heliyon. vol 9. issue 11. 2023-11-30. PMID:38034668. |
rors (95 % confidence interval) of nms for haloperidol, chlorpromazine, risperidone, and aripiprazole were 12.1 (11.1-13.3), 6.3 (5.7-7.0), 6.2 (5.8-6.6), and 4.7 (4.4-5.1), respectively. |
2023-11-30 |
2023-12-10 |
Not clear |
| Salam Salloum-Asfar, Nasser Zawia, Sara A Abdull. Retracing our steps: A review on autism research in children, its limitation and impending pharmacological interventions. Pharmacology & therapeutics. 2023-11-26. PMID:38008401. |
additionally, psychotropic drugs with different mechanisms of action have been approved to reduce associated symptoms and comorbidities, including aripiprazole, risperidone, and haloperidol for irritability and aggression, methylphenidate, atomoxetine, clonidine, and guanfacine for adhd, and melatonin for sleep disturbances. |
2023-11-26 |
2023-11-28 |
Not clear |
| Sanja Strbe, Ivan Maria Smoday, Ivan Krezic, Luka Kalogjera, Vlasta Vukovic, Helena Zizek, Slaven Gojkovic, Hrvoje Vranes, Ivan Barisic, Suncana Sikiric, Marijan Tepes, Katarina Oroz, Filip Brkic, Martin Drinkovic, Lidija Beketic Oreskovic, Jelena Popic, Alenka Boban Blagaic, Anita Skrtic, Mario Staresinic, Sven Seiwerth, Predrag Sikiri. Innate Vascular Failure by Application of Neuroleptics, Amphetamine, and Domperidone Rapidly Induced Severe Occlusion/Occlusion-like Syndromes in Rats and Stable Gastric Pentadecapeptide BPC 157 as Therapy. Pharmaceuticals (Basel, Switzerland). vol 16. issue 6. 2023-06-28. PMID:37375736. |
in rats with complete calvariectomy, medication (bpc 157 10 µg/kg, 10 ng/kg ip or ig) was given 5 min after distinctive dopamine agents (mg/kg ip) (haloperidol (5), fluphenazine (5), clozapine (10), risperidone (5), olanzapine (10), quetiapine (10), or aripiprazole (10), domperidone (25), amphetamine (10), and combined amphetamine and haloperidol) and assessed at 15 min thereafter. |
2023-06-28 |
2023-08-14 |
rat |
| Stefan Leucht, Johannes Schneider-Thoma, Angelika Burschinski, Natalie Peter, Dongfang Wang, Shimeng Dong, Maximilian Huhn, Adriani Nikolakopoulou, Georgia Salanti, John M Davi. Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis. World psychiatry : official journal of the World Psychiatric Association (WPA). vol 22. issue 2. 2023-05-10. PMID:37159349. |
in terms of overall symptoms, olanzapine was on average more efficacious than ziprasidone (standardized mean difference, smd=0.37, 95% ci: 0.26-0.49), asenapine (smd=0.33, 95% ci: 0.21-0.45), iloperidone (smd=0.32, 95% ci: 0.15-0.49), paliperidone (smd=0.28, 95% ci: 0.11-0.44), haloperidol (smd=0.27, 95% ci: 0.14-0.39), quetiapine (smd=0.25, 95% ci: 0.12-0.38), aripiprazole (smd=0.16, 95% ci: 0.04-0.28) and risperidone (smd=0.12, 95% ci: 0.03-0.21). |
2023-05-10 |
2023-08-14 |
human |
| Johanna Seifert, Hannah B Maier, Sermin Toto, Dominik Dabber. [Clinical use of psychotropic drugs: A look at antipsychotic drugs]. Deutsche medizinische Wochenschrift (1946). vol 148. issue 9. 2023-04-24. PMID:37094591. |
in addition, the pharmacological receptor profiles of frequently used antipsychotic drugs (e.g., risperidone, haloperidol, quetiapine, aripiprazole) are presented and the expected adverse drug reactions, such as extrapyramidal symptoms and hyperprolactinemia, are explained. |
2023-04-24 |
2023-08-14 |
Not clear |
| Somdatta Saha, Javier González-Maes. The crosstalk between 5-HT Neuropharmacology. 2023-03-08. PMID:36889432. |
first generation or typical such as haloperidol and second generation or atypical such as clozapine and risperidone remain the current standard for schizophrenia treatment. |
2023-03-08 |
2023-08-14 |
Not clear |
| Takahiro Ito, Mikio Yoshida, Tomomi Aida, Itaru Kushima, Yuka Hiramatsu, Maiko Ono, Akira Yoshimi, Kohichi Tanaka, Norio Ozaki, Yukihiro Nod. Astrotactin2 (ASTN2) regulates emotional and cognitive functions by affecting neuronal morphogenesis and monoaminergic systems. Journal of neurochemistry. 2023-02-22. PMID:36807153. |
some behavioral abnormalities, such as increased exploratory activity and impulsivity, or decreased exploratory preference were specifically attenuated by risperidone, but not by haloperidol. |
2023-02-22 |
2023-08-14 |
mouse |
| Malgorzata Zaremba, Pawel Serafin, Patrycja Kleczkowsk. Antipsychotic Drugs Efficacy in Dextromethorphan-Induced Psychosis. Biomedicines. vol 11. issue 1. 2023-01-21. PMID:36672631. |
atypical neuroleptics (i.e., olanzapine, risperidone, quetiapine) and typical haloperidol have been used in symptomatic treatment due to their efficacy, especially in positive symptoms (hallucinations and delusions). |
2023-01-21 |
2023-08-14 |
Not clear |
| Patrick Vincent Marloth, Martin Riis Ladefoged, Magnus Spangsberg Boese. [Neuroleptic malignant syndrome caused by olanzapine, risperidone and haloperidol]. Ugeskrift for laeger. vol 184. issue 45. 2022-11-08. PMID:36345898. |
[neuroleptic malignant syndrome caused by olanzapine, risperidone and haloperidol]. |
2022-11-08 |
2023-08-14 |
Not clear |
| Patrick Vincent Marloth, Martin Riis Ladefoged, Magnus Spangsberg Boese. [Neuroleptic malignant syndrome caused by olanzapine, risperidone and haloperidol]. Ugeskrift for laeger. vol 184. issue 45. 2022-11-08. PMID:36345898. |
this is a case report of a 27-year-old man who developed neuroleptic malignant syndrome after administration of olanzapine, risperidone and haloperidol. |
2022-11-08 |
2023-08-14 |
Not clear |
| Sibi Joseph, Jerry George, Mongezi Tau, Lourdes de Fatima Ibanez-Valdes, Thozama Dubula, Humberto Foyaca-Siba. Case Report: Neuroleptic malignant syndrome in a HIV-positive patient. F1000Research. vol 9. 2022-09-08. PMID:36072922. |
we report a 29-year-old, hiv-positive woman being treated with antipsychotic medication for psychosis (clopixol 200mg intramuscularly monthly, risperidone 2mg orally daily haloperidol 2.5mg twice a day), who presented with neuroleptic malignant syndrome. |
2022-09-08 |
2023-08-14 |
Not clear |
| Meng He, Jun Fan, Ruqin Zhou, Guanbin Gao, Ruoxi Li, YuFeng Zuo, Benben Li, Yanmei Li, Taolei Su. NLRP3/Caspase-1-Mediated Pyroptosis of Astrocytes Induced by Antipsychotics Is Inhibited by a Histamine H1 Receptor-Selective Agonist. Frontiers in aging neuroscience. vol 14. 2022-05-26. PMID:35615587. |
twenty-four hour treatment with olanzapine, quetiapine, risperidone, or haloperidol dose-dependently increased the protein expression of astrocytic nlrp3, nlrp6, caspase-1, caspase-4, and gsdmd. |
2022-05-26 |
2023-08-13 |
Not clear |
| Meng He, Jun Fan, Ruqin Zhou, Guanbin Gao, Ruoxi Li, YuFeng Zuo, Benben Li, Yanmei Li, Taolei Su. NLRP3/Caspase-1-Mediated Pyroptosis of Astrocytes Induced by Antipsychotics Is Inhibited by a Histamine H1 Receptor-Selective Agonist. Frontiers in aging neuroscience. vol 14. 2022-05-26. PMID:35615587. |
co-treatment with a histamine h1 receptor agonist, 2-(3-trifluoromethylphenyl) histamine (fmph), dose-dependently reduced the increased expression of nlrp3, caspase-1 and gsdmd induced by olanzapine, quetiapine, risperidone, or haloperidol. |
2022-05-26 |
2023-08-13 |
Not clear |
| Chiung-Mei Chen, Kuo-Hsuan Chang, Chun-Li Wang, Hui-Tzu Tu, Yu-Tung Huang, Hsiu-Chuan Wu, Chien-Hung Chang, Shang-Hung Chan. Major Bleeding Risk in Atrial Fibrillation Patients Co-Medicated With Non-Vitamin K Oral Anticoagulants and Antipsychotics. Frontiers in pharmacology. vol 13. 2022-05-02. PMID:35496319. |
the concomitant use of a noac with chlorpromazine (aird: 103.87, 95% ci: 51.22-156.52), haloperidol (aird: 149.52, 95% ci: 125.03-174.00), prochlorperazine (aird: 90.43, 95% ci: 78.55-102.32), quetiapine (aird: 44.6, 95% ci: 37.11-52.09), or risperidone (aird: 41.55, 95% ci: 22.86-60.24) (all |
2022-05-02 |
2023-08-13 |
Not clear |
| Michael Spedding, Claude Sebban, Thérèse M Jay, Cyril Rocher, Brigitte Tesolin-Decros, Paul Chazot, Esther Schenker, Gabor Szénási, György I Lévay, Katalin Megyeri, Jozsef Barkóczy, Laszlo G Hársing, Ian Thomson, Mark O Cunningham, Miles A Whittington, Lori-An Etherington, Jeremy J Lambert, Ferenc A Antoni, Istvan Gacsály. Phenotypical Screening on Neuronal Plasticity in Hippocampal-Prefrontal Cortex Connectivity Reveals an Antipsychotic with a Novel Profile. Cells. vol 11. issue 7. 2022-04-12. PMID:35406745. |
egis 11150 enhanced h-pfc coherence, and increased the 8-9 hz theta band of the eeg power spectrum (from 0.002 mg/kg i.p, at >30× lower doses than clozapine, and >100× for olanzapine, risperidone, or haloperidol). |
2022-04-12 |
2023-08-13 |
Not clear |