| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Özge Türkoğlu, Aygün Ertuğru. The Role of Cannabis in the Development of Psychosis. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 35. issue 3. 2024-09-03. PMID:39224996. |
studies showed that the endocannabinoid system, which plays a role in nervous system development and functions as a homeostatic regulator in physiological processes, is affected by cannabis use during critical periods of development like adolescence; cannabis use affects physiological processes such as synaptic pruning due to the effects of this system on neurotransmitters like glutamate and dopamine leading to long-term behavioral and psychological consequences. |
2024-09-03 |
2024-09-05 |
Not clear |
| Cathy Davies, Matthijs G Bossong, Daniel Martins, Robin Wilson, Elizabeth Appiah-Kusi, Grace Blest-Hopley, Paul Allen, Fernando Zelaya, David J Lythgoe, Michael Brammer, Jesus Perez, Philip McGuire, Sagnik Bhattacharyy. Hippocampal Glutamate, Resting Perfusion and the Effects of Cannabidiol in Psychosis Risk. Schizophrenia bulletin open. vol 4. issue 1. 2024-08-15. PMID:39145348. |
hippocampal glutamate, resting perfusion and the effects of cannabidiol in psychosis risk. |
2024-08-15 |
2024-08-17 |
human |
| Cathy Davies, Matthijs G Bossong, Daniel Martins, Robin Wilson, Elizabeth Appiah-Kusi, Grace Blest-Hopley, Paul Allen, Fernando Zelaya, David J Lythgoe, Michael Brammer, Jesus Perez, Philip McGuire, Sagnik Bhattacharyy. Hippocampal Glutamate, Resting Perfusion and the Effects of Cannabidiol in Psychosis Risk. Schizophrenia bulletin open. vol 4. issue 1. 2024-08-15. PMID:39145348. |
whether glutamatergic dysfunction is related to cerebral perfusion in patients at clinical high risk (chr) for psychosis, and whether cannabidiol (cbd) has ameliorative effects on glutamate or its relationship with perfusion remains unknown. |
2024-08-15 |
2024-08-17 |
human |
| Pukar Khanal, Vishal S Patil, Kunal Bhattacharya, B M Pati. Multifaceted targets of cannabidiol in epilepsy: Modulating glutamate signaling and beyond. Computers in biology and medicine. vol 179. 2024-07-24. PMID:39047503. |
multifaceted targets of cannabidiol in epilepsy: modulating glutamate signaling and beyond. |
2024-07-24 |
2024-07-28 |
Not clear |
| Pukar Khanal, Vishal S Patil, Kunal Bhattacharya, B M Pati. Multifaceted targets of cannabidiol in epilepsy: Modulating glutamate signaling and beyond. Computers in biology and medicine. vol 179. 2024-07-24. PMID:39047503. |
even though some studies propose that cannabidiol may manipulate glutamatergic signals, there is insufficient evidence to support cannabidiol direct effect on glutamate signaling, which is important in intervening epilepsy. |
2024-07-24 |
2024-07-28 |
Not clear |
| Pukar Khanal, Vishal S Patil, Kunal Bhattacharya, B M Pati. Multifaceted targets of cannabidiol in epilepsy: Modulating glutamate signaling and beyond. Computers in biology and medicine. vol 179. 2024-07-24. PMID:39047503. |
glutamate receptor 2 was identified to be genetically varied in epilepsy which was targeted by cannabidiol and its expression was increased with its treatment. |
2024-07-24 |
2024-07-28 |
Not clear |
| Pukar Khanal, Vishal S Patil, Kunal Bhattacharya, B M Pati. Multifaceted targets of cannabidiol in epilepsy: Modulating glutamate signaling and beyond. Computers in biology and medicine. vol 179. 2024-07-24. PMID:39047503. |
more importantly, cannabidiol showed a direct binding affinity with glutamate receptor 2 forming a stable hydrophilic interaction and comparatively lower root mean squared deviation and residual fluctuations, increasing protein compactness with broad conformational changes. |
2024-07-24 |
2024-07-28 |
Not clear |
| Pukar Khanal, Vishal S Patil, Kunal Bhattacharya, B M Pati. Multifaceted targets of cannabidiol in epilepsy: Modulating glutamate signaling and beyond. Computers in biology and medicine. vol 179. 2024-07-24. PMID:39047503. |
based on the cheminformatic target fishing, evaluation of differentially expressed genes, molecular docking, and simulations, it can be hypothesized that cannabidiol may possess glutamate receptor 2-mediated anti-epileptic activities. |
2024-07-24 |
2024-07-28 |
Not clear |
| Kawsar U Chowdhury, Madison Elizabeth Holden, Miles T Wiley, Vishnu Suppiramaniam, Miranda N Ree. Effects of Cannabis on Glutamatergic Neurotransmission: The Interplay between Cannabinoids and Glutamate. Cells. vol 13. issue 13. 2024-07-12. PMID:38994982. |
effects of cannabis on glutamatergic neurotransmission: the interplay between cannabinoids and glutamate. |
2024-07-12 |
2024-07-14 |
Not clear |
| Kawsar U Chowdhury, Madison Elizabeth Holden, Miles T Wiley, Vishnu Suppiramaniam, Miranda N Ree. Effects of Cannabis on Glutamatergic Neurotransmission: The Interplay between Cannabinoids and Glutamate. Cells. vol 13. issue 13. 2024-07-12. PMID:38994982. |
acute exposure to cannabis typically inhibits glutamate release, whereas chronic use tends to increase glutamate release. |
2024-07-12 |
2024-07-14 |
Not clear |
| Kawsar U Chowdhury, Madison Elizabeth Holden, Miles T Wiley, Vishnu Suppiramaniam, Miranda N Ree. Effects of Cannabis on Glutamatergic Neurotransmission: The Interplay between Cannabinoids and Glutamate. Cells. vol 13. issue 13. 2024-07-12. PMID:38994982. |
conversely, the postsynaptic alterations are more complicated than the presynaptic effects, as cannabis can affect the glutamate receptor expression and the downstream signaling of glutamate. |
2024-07-12 |
2024-07-14 |
Not clear |
| Christopher Martínez-Aguirre, Luis Alfredo Márquez, Cindy Lizbeth Santiago-Castañeda, Francia Carmona-Cruz, Maria de Los Angeles Nuñez-Lumbreras, Vladimir A Martínez-Rojas, Mario Alonso-Vanegas, Gustavo Aguado-Carrillo, Norma L Gómez-Víquez, Emilio J Galván, Manola Cuéllar-Herrera, Luisa Roch. Cannabidiol Modifies the Glutamate Over-Release in Brain Tissue of Patients and Rats with Epilepsy: A Pilot Study. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137458. |
cannabidiol modifies the glutamate over-release in brain tissue of patients and rats with epilepsy: a pilot study. |
2023-12-23 |
2023-12-25 |
rat |
| Christopher Martínez-Aguirre, Luis Alfredo Márquez, Cindy Lizbeth Santiago-Castañeda, Francia Carmona-Cruz, Maria de Los Angeles Nuñez-Lumbreras, Vladimir A Martínez-Rojas, Mario Alonso-Vanegas, Gustavo Aguado-Carrillo, Norma L Gómez-Víquez, Emilio J Galván, Manola Cuéllar-Herrera, Luisa Roch. Cannabidiol Modifies the Glutamate Over-Release in Brain Tissue of Patients and Rats with Epilepsy: A Pilot Study. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137458. |
studies support the idea that cannabidiol (cbd) decreases glutamate over-release. |
2023-12-23 |
2023-12-25 |
rat |
| Kamyar Keramatian, Trisha Chakrabarty, Anais DuBois, Gayatri Saraf, Lakshmi N Yatha. New Pharmacologic Approaches to the Treatment of Bipolar Depression. Drugs. 2023-05-25. PMID:37227597. |
included are new atypical anti-psychotics, glutamate modulators (ketamine and cycloserine/lurasidone), neurosteroid modulators (zuranolone), anti-inflammatories and mitochondrial modulators, cannabidiol (cbd) and psilocybin. |
2023-05-25 |
2023-08-14 |
Not clear |
| Chun S Zuo, Scott E Luka. Chronic cannabis use alters dACC-striatal glutamatergic balance. Pharmacology, biochemistry, and behavior. 2023-04-02. PMID:37004979. |
we recently quantified the difference in regional glutamate of dorsal anterior cingulate (dacc) and striatum regions in the frontostriatal pathway using proton mrs at baseline and on verified abstinent days 7 and 21 in chronic users of cannabis (n = 20) in comparison with age- and sex- matched non-using controls (n = 10). |
2023-04-02 |
2023-08-14 |
human |
| Cindy Santiago-Castañeda, Saúl Huerta de la Cruz, Christopher Martínez-Aguirre, Sandra Adela Orozco-Suárez, Luisa Roch. Cannabidiol Reduces Short- and Long-Term High Glutamate Release after Severe Traumatic Brain Injury and Improves Functional Recovery. Pharmaceutics. vol 14. issue 8. 2022-08-26. PMID:36015236. |
cannabidiol reduces short- and long-term high glutamate release after severe traumatic brain injury and improves functional recovery. |
2022-08-26 |
2023-08-14 |
rat |
| Cindy Santiago-Castañeda, Saúl Huerta de la Cruz, Christopher Martínez-Aguirre, Sandra Adela Orozco-Suárez, Luisa Roch. Cannabidiol Reduces Short- and Long-Term High Glutamate Release after Severe Traumatic Brain Injury and Improves Functional Recovery. Pharmaceutics. vol 14. issue 8. 2022-08-26. PMID:36015236. |
this study aimed to determine if orally administered cannabidiol (cbd) lessens the cortical over-release of glutamate induced by a severe traumatic brain injury (tbi) and facilitates functional recovery. |
2022-08-26 |
2023-08-14 |
rat |
| Chun S Zuo, Katherine A Davis, Scott E Luka. Lower dACC glutamate in cannabis users during early phase abstinence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-04-28. PMID:35484401. |
lower dacc glutamate in cannabis users during early phase abstinence. |
2022-04-28 |
2023-08-13 |
Not clear |
| Chun S Zuo, Katherine A Davis, Scott E Luka. Lower dACC glutamate in cannabis users during early phase abstinence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-04-28. PMID:35484401. |
we hypothesize that regional glutamate is associated with the cannabis withdrawal syndrome and recently examined possible association of glutamate with cannabis withdrawal, using magnetic resonance spectroscopy (mrs), in non-treatment-seeking cannabis users. |
2022-04-28 |
2023-08-13 |
Not clear |
| Chun S Zuo, Katherine A Davis, Scott E Luka. Lower dACC glutamate in cannabis users during early phase abstinence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-04-28. PMID:35484401. |
dorsal anterior cingulate cortex (dacc) glutamate and γ-amino butyric acid (gaba) were measured with proton mrs at baseline and on abstinent days 7 and 21 in conjunction with measures of cannabis withdrawal and craving (mcq), sleep difficulties (psqi) and mood state. |
2022-04-28 |
2023-08-13 |
Not clear |