| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jun Yang, Rui-Ning Ma, Jia-Min Dong, Shu-Qun Hu, Yong Liu, Jing-Zhi Ya. Phosphorylation of 4.1N by CaMKII regulates the trafficking of GluA1-containing AMPA receptors during long-term potentiation in acute rat hippocampal brain slices. Neuroscience. 2023-11-22. PMID:37993087. |
phosphorylation of 4.1n by camkii regulates the trafficking of glua1-containing ampa receptors during long-term potentiation in acute rat hippocampal brain slices. |
2023-11-22 |
2023-11-29 |
rat |
| Misato Yoshikawa, Katsuya Suemar. Prenatal folate deficiency impairs sociability and memory/recognition in mice offspring. Brain research. 2023-10-20. PMID:37858854. |
furthermore, we measured protein expression levels of the nmda and ampa receptors, as well as psd-95 and the gaba-synthesizing enzymes gad65/67 in the frontal cortex and hippocampus. |
2023-10-20 |
2023-11-08 |
mouse |
| Mihai Ceanga, Vahid Rahmati, Holger Haselmann, Lars Schmidl, Daniel Hunter, Anna-Katherina Brauer, Sabine Liebscher, Jakob Kreye, Harald Pr\\xc3\\xbcss, Laurent Groc, Stefan Hallermann, Josep Dalmau, Alessandro Ori, Manfred Heckmann, Christian Gei. Human NMDAR autoantibodies disrupt excitatory-inhibitory balance, leading to hippocampal network hypersynchrony. Cell reports. vol 42. issue 10. 2023-09-28. PMID:37768823. |
after passive transfer of patients' cerebrospinal fluid or human monoclonal anti-glun1-autoantibodies in mice, we find a disrupted excitatory-inhibitory balance resulting from ca1 neuronal hypoexcitability, reduced ampa receptor (ampar) signaling, and faster synaptic inhibition in acute hippocampal slices. |
2023-09-28 |
2023-10-07 |
mouse |
| Zhen-Fu Jiang, Li-Na Xuan, Xiao-Wan Sun, Shao-Bo Liu, Jian Yi. Knockdown of SIK3 in the CA1 Region can Reduce Seizure Susceptibility in Mice by Inhibiting Decreases in GABA Molecular neurobiology. 2023-09-16. PMID:37715891. |
in cultured hippocampal neurons, we used pterosin b, a selective sik3 inhibitor that can inhibit epileptiform discharges induced by the convulsant drug cyclothiazide (a positive allosteric modulator of ampa receptors, ctz). |
2023-09-16 |
2023-10-07 |
mouse |
| Lucia Caffino, Giorgia Targa, Anne Stephanie Mallien, Francesca Mottarlini, Beatrice Rizzi, Judith R Homberg, Peter Gass, Fabio Fumagall. Chronic Lithium Treatment Alters NMDA and AMPA Receptor Synaptic Availability and Dendritic Spine Organization in the Rat Hippocampus. Current neuropharmacology. 2023-09-15. PMID:37711124. |
chronic lithium treatment alters nmda and ampa receptor synaptic availability and dendritic spine organization in the rat hippocampus. |
2023-09-15 |
2023-10-07 |
rat |
| Ayae Nomura, Kazuhiro Kurokawa, Kohei Takahashi, Kazuya Miyagawa, Atsumi Mochida-Saito, Hiroshi Takeda, Minoru Tsuj. Possible involvement of inflammasomes on the post-stroke cognitive impairment in a mouse model of embolic cerebral infarct. Physiology & behavior. 2023-09-14. PMID:37709001. |
furthermore, the phosphorylated \xce\xb1-amino-3hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor subunit glutamate receptor 1 (glur1) at ser 831 and ser 845 protein was found to be significantly decreased in the dorsal hippocampus of eci mice. |
2023-09-14 |
2023-10-07 |
mouse |
| Ayae Nomura, Kazuhiro Kurokawa, Kohei Takahashi, Kazuya Miyagawa, Atsumi Mochida-Saito, Hiroshi Takeda, Minoru Tsuj. Possible involvement of inflammasomes on the post-stroke cognitive impairment in a mouse model of embolic cerebral infarct. Physiology & behavior. 2023-09-14. PMID:37709001. |
these results indicate that development of psci after embolic cerebral infarction is due to a decrease in ampa receptor subunit glur1 at ser831 and ser845 through the inflammasome activation pathway in the dorsal hippocampus. |
2023-09-14 |
2023-10-07 |
mouse |
| Tatyana Y Postnikova, Alexandra V Griflyuk, Arseniy S Zhigulin, Elena B Soboleva, Oleg I Barygin, Dmitry V Amakhin, Aleksey V Zaitse. Febrile Seizures Cause a Rapid Depletion of Calcium-Permeable AMPA Receptors at the Synapses of Principal Neurons in the Entorhinal Cortex and Hippocampus of the Rat. International journal of molecular sciences. vol 24. issue 16. 2023-08-26. PMID:37628802. |
febrile seizures cause a rapid depletion of calcium-permeable ampa receptors at the synapses of principal neurons in the entorhinal cortex and hippocampus of the rat. |
2023-08-26 |
2023-09-07 |
rat |
| Duk-Shin Lee, Tae-Hyun Kim, Hana Park, Ji-Eun Ki. PDI augments kainic acid-induced seizure activity and neuronal death by inhibiting PP2A-GluA2-PICK1-mediated AMPA receptor internalization in the mouse hippocampus. Scientific reports. vol 13. issue 1. 2023-08-25. PMID:37626185. |
pdi augments kainic acid-induced seizure activity and neuronal death by inhibiting pp2a-glua2-pick1-mediated ampa receptor internalization in the mouse hippocampus. |
2023-08-25 |
2023-09-07 |
mouse |
| Lei Chen, Qiang Fu, Yang Du, Zhong-Yong Jiang, Yong Chen. Transcriptome Analysis and Epigenetics Regulation in the Hippocampus and the Prefrontal Cortex of VPA-Induced Rat Model. Molecular neurobiology. 2023-08-17. PMID:37592184. |
further, the predicted and validated target mrna of de mirna enriched pathways involved neurotransmitter uptake, long-term synaptic depression, and ampa receptor complex (anti-glua2-b) in the hippocampus; as well as the neuroactive ligand-receptor interaction and regulation of postsynaptic membrane potential in the prefrontal cortex. |
2023-08-17 |
2023-09-07 |
rat |
| Elisabetta Gerace, Lorenzo Curti, Lucia Caffino, Elisabetta Bigagli, Francesca Mottarlini, Fernando Castillo D\\xc3\\xadaz, Alice Ilari, Cristina Luceri, Carlo Dani, Fabio Fumagalli, Alessio Masi, Guido Mannaion. Ethanol-induced AMPA alterations are mediated by mGLU5 receptors through miRNA upregulation in hippocampal slices. European journal of pharmacology. 2023-07-11. PMID:37433363. |
ethanol-induced ampa alterations are mediated by mglu5 receptors through mirna upregulation in hippocampal slices. |
2023-07-11 |
2023-08-14 |
Not clear |
| Elisabetta Gerace, Lorenzo Curti, Lucia Caffino, Elisabetta Bigagli, Francesca Mottarlini, Fernando Castillo D\\xc3\\xadaz, Alice Ilari, Cristina Luceri, Carlo Dani, Fabio Fumagalli, Alessio Masi, Guido Mannaion. Ethanol-induced AMPA alterations are mediated by mGLU5 receptors through miRNA upregulation in hippocampal slices. European journal of pharmacology. 2023-07-11. PMID:37433363. |
we have recently demonstrated that chronic etoh exposure, followed by withdrawal, induces a significant decrease in ampa receptor (ampar) expression and function in developing hippocampus in vitro. |
2023-07-11 |
2023-08-14 |
Not clear |
| Ana Bel\\xc3\\xa9n Sanz-Martos, Esmeralda Fuentes-Verdugo, Beatriz Merino, Lidia Morales, Vicente P\\xc3\\xa9rez, Roberto Capell\\xc3\\xa1n, Ricardo Pell\\xc3\\xb3n, Miguel Migu\\xc3\\xa9ns, Nuria Del Olm. SCHEDULE-INDUCED ALCOHOL INTAKE DURING ADOLESCENCE SEX DEPENDENTLY IMPAIRS HIPPOCAMPAL SYNAPTIC PLASTICITY AND SPATIAL MEMORY. Behavioural brain research. 2023-07-09. PMID:37423317. |
in contrast, alcohol did not modify hippocampal gene expression of ampa and nmda glutamate receptor subunits, although there are differences in the expression levels of several genes relevant to synaptic plasticity mechanisms underlying learning and memory processes, related to alcohol consumption as ephb2, sex differences as pi3k or the interaction of both factors such as pten. |
2023-07-09 |
2023-08-14 |
rat |
| Chengzhang Li, Zhenrong Li, Sihan Xu, Sanwei Jiang, Zhenli Ye, Bin Yu, Shixiang Gong, Junmei Li, Qilin Hu, Bingyan Feng, Mengmeng Wang, Chengbiao L. Exogenous AMPA downregulates gamma-frequency network oscillation in CA3 of rat hippocampal slices. Scientific reports. vol 13. issue 1. 2023-06-29. PMID:37386056. |
exogenous ampa downregulates gamma-frequency network oscillation in ca3 of rat hippocampal slices. |
2023-06-29 |
2023-08-14 |
rat |
| Chengzhang Li, Zhenrong Li, Sihan Xu, Sanwei Jiang, Zhenli Ye, Bin Yu, Shixiang Gong, Junmei Li, Qilin Hu, Bingyan Feng, Mengmeng Wang, Chengbiao L. Exogenous AMPA downregulates gamma-frequency network oscillation in CA3 of rat hippocampal slices. Scientific reports. vol 13. issue 1. 2023-06-29. PMID:37386056. |
however, we demonstrated that\xc2\xa0exogenous ampa dose-dependently inhibited carbachol (cch)-induced \xce\xb3 oscillation in the ca3 area of rat hippocampal slices, but the underlying mechanism is not clear. |
2023-06-29 |
2023-08-14 |
rat |
| Vaskar Das, Michael B Basovich, Craig J Thomas, Jeffrey S Kroin, Asokumar Buvanendran, Robert J McCarth. A Pharmacological Evaluation of the Analgesic Effect and Hippocampal Protein Modulation of the Ketamine Metabolite (2R,6R)-Hydroxynorketamine in Murine Pain Models. Anesthesia and analgesia. 2023-06-15. PMID:37319016. |
the purpose of this study was to evaluate the \xce\xb1-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (ampa) dependence of (2r,6r)-hnk analgesia and protein changes in the hippocampus in murine pain models administered (2r,6r)-hnk or saline. |
2023-06-15 |
2023-08-14 |
Not clear |
| Guillermo Iborra-L\\xc3\\xa1zaro, Souhail Djebari, Irene S\\xc3\\xa1nchez-Rodr\\xc3\\xadguez, Esther Gratac\\xc3\\xb2s-Batlle, Nuria S\\xc3\\xa1nchez-Fern\\xc3\\xa1ndez, Marija Rado\\xc5\\xa1evi\\xc4\\x87, N\\xc3\\xbaria Casals, Juan de Dios Navarro-L\\xc3\\xb3pez, David Soto Del Cerro, Lydia Jim\\xc3\\xa9nez-D\\xc3\\xada. CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative, and non-associative learning. The Journal of physiology. 2023-06-13. PMID:37309891. |
its deficiency has been recently shown to disrupt dendritic spine maturation and ampa receptor synthesis and trafficking in the hippocampus, but its contribution to synaptic plasticity and cognitive learning and memory processes remains mostly unknown. |
2023-06-13 |
2023-08-14 |
mouse |
| Guillermo Iborra-L\\xc3\\xa1zaro, Souhail Djebari, Irene S\\xc3\\xa1nchez-Rodr\\xc3\\xadguez, Esther Gratac\\xc3\\xb2s-Batlle, Nuria S\\xc3\\xa1nchez-Fern\\xc3\\xa1ndez, Marija Rado\\xc5\\xa1evi\\xc4\\x87, N\\xc3\\xbaria Casals, Juan de Dios Navarro-L\\xc3\\xb3pez, David Soto Del Cerro, Lydia Jim\\xc3\\xa9nez-D\\xc3\\xada. CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative, and non-associative learning. The Journal of physiology. 2023-06-13. PMID:37309891. |
key points: cpt1c, a neuron-specific interactor protein involved in ampa receptors synthesis and trafficking, was found highly expressed in the hippocampus, amygdala and various motor regions. |
2023-06-13 |
2023-08-14 |
mouse |
| Guillermo Iborra-L\\xc3\\xa1zaro, Souhail Djebari, Irene S\\xc3\\xa1nchez-Rodr\\xc3\\xadguez, Esther Gratac\\xc3\\xb2s-Batlle, Nuria S\\xc3\\xa1nchez-Fern\\xc3\\xa1ndez, Marija Rado\\xc5\\xa1evi\\xc4\\x87, N\\xc3\\xbaria Casals, Juan de Dios Navarro-L\\xc3\\xb3pez, David Soto Del Cerro, Lydia Jim\\xc3\\xa9nez-D\\xc3\\xada. CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative, and non-associative learning. The Journal of physiology. 2023-06-13. PMID:37309891. |
abstract figure legend cpt1c regulates the trafficking of ampa receptors (ampars) containing the glua1 subunit to the membrane surface and the maturation of dendritic spines in the hippocampus. |
2023-06-13 |
2023-08-14 |
mouse |
| Ga-Young Choi, Hyun-Bum Kim, Jae-Min Cho, Inturu Sreelatha, In-Seo Lee, Hee-Seok Kweon, Sehyun Sul, Sun Ae Kim, Sungho Maeng, Ji-Ho Par. Umbelliferone Ameliorates Memory Impairment and Enhances Hippocampal Synaptic Plasticity in Scopolamine-Induced Rat Model. Nutrients. vol 15. issue 10. 2023-05-27. PMID:37242234. |
a hippocampal tissue analysis revealed that umb attenuated a scop-induced blockade of field excitatory post-synaptic potential (fepsp) activity and ameliorated the impairment of ltp by the nmda and ampa receptor antagonists. |
2023-05-27 |
2023-08-14 |
rat |