All Relations between \u03b1-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and hippocampus

Publication Sentence Publish Date Extraction Date Species
Daniel Choquet, Melina Petrel, Mónica Fernández-Monrea. Targeting of membrane proteins with fluoronanogold probes for high-resolution correlative microscopy. Methods in cell biology. vol 187. 2024-05-05. PMID:38705630. we use hippocampal organotypic slices from a previously reported mouse model expressing a modified ampa receptor (ampar) subunit that binds biotin at the surface (getz et al., 2022). 2024-05-05 2024-05-08 mouse
Valery Petrovich Zinchenko, Ilia Yu Teplov, Artem Mikhailovich Kosenkov, Sergei Gennadievich Gaidin, Bakytzhan Kairatuly Kairat, Sultan Tuleukhanovich Tuleukhano. Participation of calcium-permeable AMPA receptors in the regulation of epileptiform activity of hippocampal neurons. Frontiers in synaptic neuroscience. vol 16. 2024-04-05. PMID:38577639. participation of calcium-permeable ampa receptors in the regulation of epileptiform activity of hippocampal neurons. 2024-04-05 2024-04-07 Not clear
Sohrab Anvari, Mohammad Javan, Javad Mirnajafi-Zadeh, Yaghoub Fathollah. Repeated Morphine Exposure Alters Temporoamonic-CA1 Synaptic Plasticity in Male Rat Hippocampus. Neuroscience. 2024-03-21. PMID:38513764. furthermore, rme did not affect the expression of nr2a, ampa receptor subunits, and γ2gabaa and gabab receptors in either segment of the hippocampus. 2024-03-21 2024-03-24 rat
Nicholas R Mill, Richard H Ogoe, Nazanin Valibeigi, Diyi Chen, Carmen L Kimbal, Stanley J Yoon, Shaunak Ganju, Josue A Perdomo, Anjali Sardana, Daniel G McHail, Diego A Gonzalez, Theodore C Duma. Positive modulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors differentially alters spatial learning and memory in juvenile rats younger and older than three weeks. Behavioural pharmacology. vol 35. issue 2-3. 2024-03-07. PMID:38451022. previously, we discovered that developmental modifications to hippocampal glutamatergic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptors in juvenile rats was related to more mature spontaneous alternation behavior in a symmetrical y-maze. 2024-03-07 2024-03-09 rat
Nicholas R Mill, Richard H Ogoe, Nazanin Valibeigi, Diyi Chen, Carmen L Kimbal, Stanley J Yoon, Shaunak Ganju, Josue A Perdomo, Anjali Sardana, Daniel G McHail, Diego A Gonzalez, Theodore C Duma. Positive modulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors differentially alters spatial learning and memory in juvenile rats younger and older than three weeks. Behavioural pharmacology. vol 35. issue 2-3. 2024-03-07. PMID:38451022. moreover, a positive allosteric modulator of ampa receptors enabled immature rats to alternate at rates seen in older animals, suggesting an excitatory synaptic limitation to hippocampal maturation. 2024-03-07 2024-03-09 rat
Züleyha Doğanyiğit, Aslı Okan, Seher Yılmaz, A Cihangir Uğuz, Enes Akyü. Gender-related variation expressions of neuroplastin TRAF6, GluA1, GABA(A) receptor, and PMCA in cortex, hippocampus, and brainstem in an experimental epilepsy model. Synapse (New York, N.Y.). vol 78. issue 2. 2024-03-04. PMID:38436644. it was observed that neuroplastin and related proteins tnf receptor-associated factor 6 (traf6), gamma amino butyric acid type a receptors [(gaba(a)], and plasma membrane ca2+ atpase (pmca) protein immunoreactivity levels increased especially in the male hippocampus, and only ampa receptor subunit type 1 (glua1) immunoreactivity decreased, unlike other proteins. 2024-03-04 2024-03-06 rat
Mathias Delhaye, Jeffrey LeDue, Kaylie Robinson, Qin Xu, Qian Zhang, Shinichiro Oku, Peng Zhang, Ann Marie Crai. Adaptation of Magnified Analysis of the Proteome for Excitatory Synaptic Proteins in Varied Samples and Evaluation of Cell Type-Specific Distributions. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-02-15. PMID:38360747. using male and female mice expressing yfp-chr2 exclusively in interneurons, we revealed a distinct composition of ampa and nmda receptors and shank family members at synapses on hippocampal interneurons versus on pyramidal neurons. 2024-02-15 2024-02-18 mouse
Naoya Atarashi, Misaki Morishita, Shinji Matsud. Activation of innate immune receptor TLR9 by mitochondrial DNA plays essential roles in the chemical long-term depression of hippocampal neurons. The Journal of biological chemistry. 2024-02-14. PMID:38354781. in this study, we showed that the inhibition of toll-like receptor-9 (tlr9), an innate immune receptor, suppresses n-methyl-d-aspartate (nmda)-induced reduction of cell surface ampa receptors in cultured hippocampal neurons. 2024-02-14 2024-02-17 Not clear
Judit Català-Solsona, Stefano Lutzu, Pablo J Lituma, Cristina Fábregas-Ordoñez, Dolores Siedlecki, Lydia Giménez-Llort, Alfredo J Miñano-Molina, Carlos A Saura, Pablo E Castillo, José Rodriguez-Álvare. Nr4a2 blocks oAβ-mediated synaptic plasticity dysfunction and ameliorates spatial memory deficits in the APP bioRxiv : the preprint server for biology. 2024-02-08. PMID:38328087. recently, it has been reported that nr4a2, a member of the nr4a family of orphan nuclear receptors, plays a role in hippocampal synaptic plasticity by regulating bdnf and synaptic ampa receptors. 2024-02-08 2024-02-10 mouse
Hayuma Otsuka, Sachie Sasaki-Hamada, Hitoshi Ishibashi, Jun-Ichiro Ok. Hippocampal acetylcholine receptor activation-dependent long-term depression in streptozotocin-induced diabetic rats. Neuroscience letters. 2024-01-22. PMID:38253285. therefore, the present results suggest that acetylcholine receptor-mediated ltd in stz rats requires the internalization of ampa receptors on the postsynaptic surface and their intracellular effects in the hippocampus. 2024-01-22 2024-01-25 rat
Jiahui Chen, Yinlong Li, QingZhen Yu, Jimmy S Patel, Xin Zhou, Kuo Zhang, Jian Rong, Chunyu Zhao, Ahmad F Chaudhary, Wei Zhang, Chunyang Bi, Zhendong Song, April T Davenport, Ahmed Haider, James B Daunais, Lee Collier, Hongjie Yuan, Steven Lian. Preclinical Evaluation of Azabenzimidazole-Based PET Radioligands for γ-8 Dependent Transmembrane AMPA Receptor Regulatory Protein Imaging. Chembiochem : a European journal of chemical biology. 2024-01-16. PMID:38227784. ampa glutamate receptors (ampars) play a pivotal role in excitatory neurotransmission, particularly in the hippocampus where the tarp γ-8 subunit is enriched and serves as a target for emerging anti-epileptic drugs. 2024-01-16 2024-01-19 rat
Daniel P Chapman, Sarah D Power, Stefano Vicini, Tomás J Ryan, Mark P Burn. Amnesia after repeated head impact is caused by impaired synaptic plasticity in the memory engram. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-01-16. PMID:38228367. in sham mice the hippocampal engram neurons exhibited synaptic plasticity, evident in amplified ampa:nmda ratio, enhanced ampa-weighted tau, and increased dendritic spine volume compared to non-engram neurons. 2024-01-16 2024-01-19 mouse
Valérie Clavet-Fournier, ChungKu Lee, Waja Wegner, Nils Brose, JeongSeop Rhee, Katrin I Willi. Pre- and postsynaptic nanostructures increase in size and complexity after induction of long-term potentiation. iScience. vol 27. issue 1. 2024-01-12. PMID:38213627. we utilized time-lapse super-resolution sted microscopy of organotypic hippocampal brain slices and cultured neurons to visualize structural changes of the synaptic nano-organization of the postsynaptic scaffolding protein psd95, the presynaptic scaffolding protein bassoon, and the glua2 subunit of ampa receptors by chemically induced long-term potentiation (cltp) at the level of single synapses. 2024-01-12 2024-01-14 Not clear
Nestor I Martínez-Torres, Jhonathan Cárdenas-Bedoya, Blanca Mildred Vázquez-Torres, Blanca Miriam Torres-Mendoz. Environmental enrichment and cerebrolysin improve motor and cognitive performance in a rat model of stroke, in conjunction with an increase in hippocampal AMPA but not NMDA receptor subunits. Brain research. 2023-12-04. PMID:38048977. environmental enrichment and cerebrolysin improve motor and cognitive performance in a rat model of stroke, in conjunction with an increase in hippocampal ampa but not nmda receptor subunits. 2023-12-04 2023-12-10 rat
Nestor I Martínez-Torres, Jhonathan Cárdenas-Bedoya, Blanca Mildred Vázquez-Torres, Blanca Miriam Torres-Mendoz. Environmental enrichment and cerebrolysin improve motor and cognitive performance in a rat model of stroke, in conjunction with an increase in hippocampal AMPA but not NMDA receptor subunits. Brain research. 2023-12-04. PMID:38048977. this lesion provokes a disorganization of sensory-motor and cognitive systems, the latter associated with hippocampal activity, a structure in which α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) and nmda n-methyl-d-aspartate (nmda) receptors are important for the integration of information. 2023-12-04 2023-12-10 rat
Jun Yang, Rui-Ning Ma, Jia-Min Dong, Shu-Qun Hu, Yong Liu, Jing-Zhi Ya. Phosphorylation of 4.1N by CaMKII regulates the trafficking of GluA1-containing AMPA receptors during long-term potentiation in acute rat hippocampal brain slices. Neuroscience. 2023-11-22. PMID:37993087. phosphorylation of 4.1n by camkii regulates the trafficking of glua1-containing ampa receptors during long-term potentiation in acute rat hippocampal brain slices. 2023-11-22 2023-11-29 rat
Misato Yoshikawa, Katsuya Suemar. Prenatal folate deficiency impairs sociability and memory/recognition in mice offspring. Brain research. 2023-10-20. PMID:37858854. furthermore, we measured protein expression levels of the nmda and ampa receptors, as well as psd-95 and the gaba-synthesizing enzymes gad65/67 in the frontal cortex and hippocampus. 2023-10-20 2023-11-08 mouse
Mihai Ceanga, Vahid Rahmati, Holger Haselmann, Lars Schmidl, Daniel Hunter, Anna-Katherina Brauer, Sabine Liebscher, Jakob Kreye, Harald Prüss, Laurent Groc, Stefan Hallermann, Josep Dalmau, Alessandro Ori, Manfred Heckmann, Christian Gei. Human NMDAR autoantibodies disrupt excitatory-inhibitory balance, leading to hippocampal network hypersynchrony. Cell reports. vol 42. issue 10. 2023-09-28. PMID:37768823. after passive transfer of patients' cerebrospinal fluid or human monoclonal anti-glun1-autoantibodies in mice, we find a disrupted excitatory-inhibitory balance resulting from ca1 neuronal hypoexcitability, reduced ampa receptor (ampar) signaling, and faster synaptic inhibition in acute hippocampal slices. 2023-09-28 2023-10-07 mouse
Zhen-Fu Jiang, Li-Na Xuan, Xiao-Wan Sun, Shao-Bo Liu, Jian Yi. Knockdown of SIK3 in the CA1 Region can Reduce Seizure Susceptibility in Mice by Inhibiting Decreases in GABA Molecular neurobiology. 2023-09-16. PMID:37715891. in cultured hippocampal neurons, we used pterosin b, a selective sik3 inhibitor that can inhibit epileptiform discharges induced by the convulsant drug cyclothiazide (a positive allosteric modulator of ampa receptors, ctz). 2023-09-16 2023-10-07 mouse
Lucia Caffino, Giorgia Targa, Anne Stephanie Mallien, Francesca Mottarlini, Beatrice Rizzi, Judith R Homberg, Peter Gass, Fabio Fumagall. Chronic Lithium Treatment Alters NMDA and AMPA Receptor Synaptic Availability and Dendritic Spine Organization in the Rat Hippocampus. Current neuropharmacology. 2023-09-15. PMID:37711124. chronic lithium treatment alters nmda and ampa receptor synaptic availability and dendritic spine organization in the rat hippocampus. 2023-09-15 2023-10-07 rat