| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aliona Wöhler, Sabine K Gries, Rebekka J S Salzmann, Christina Krötz, Bingduo Wang, Paula Müller, Angelina Klein, Ingo G H Schmidt-Wolf, Sebastian Schaaf, Robert Schwab, Veronika Lukacs-Kornek, Arnulf G Willms, Miroslaw T Korne. Monocyte derived large extracellular vesicles in polytrauma. Journal of extracellular biology. vol 3. issue 9. 2024-09-03. PMID:39224236. |
thus, we compared our ev data to soluble biomarkers such as tumour necrosis factor alpha (tnf alpha) and interleukin-8 (il-8). |
2024-09-03 |
2024-09-05 |
Not clear |
| Aliona Wöhler, Sabine K Gries, Rebekka J S Salzmann, Christina Krötz, Bingduo Wang, Paula Müller, Angelina Klein, Ingo G H Schmidt-Wolf, Sebastian Schaaf, Robert Schwab, Veronika Lukacs-Kornek, Arnulf G Willms, Miroslaw T Korne. Monocyte derived large extracellular vesicles in polytrauma. Journal of extracellular biology. vol 3. issue 9. 2024-09-03. PMID:39224236. |
tnf alpha and il-8 levels were quantified. |
2024-09-03 |
2024-09-05 |
Not clear |
| Karim M Raafat, Ibrahim A Abdelwahab, Sally A El-Zahab. Nano-cubosomes of the phyto-active principle in Withania somnifera: LC-MS-NMR, anti-microbial, and insights of the anti-neuropathic and anti-inflammatory mechanism. Fitoterapia. 2024-09-01. PMID:39218231. |
moreover, the ws, wda, and cub 1-3 anti-inflammatory mechanism might be due to the amelioration of the pro-inflammatory serum cytokines (decreasing tnf alpha and il-six levels and increasing il-ten). |
2024-09-01 |
2024-09-04 |
Not clear |
| Çağrı Coşkun, Şule Üna. Deficiency of Adenosine Deaminase 2. Turkish journal of haematology : official journal of Turkish Society of Haematology. 2024-08-09. PMID:39120005. |
currently, tnf alpha inhibitors are the treatment of choice for controlling vasculitis manifestations and preventing strokes. |
2024-08-09 |
2024-08-12 |
Not clear |
| Çağrı Coşkun, Şule Üna. Deficiency of Adenosine Deaminase 2. Turkish journal of haematology : official journal of Turkish Society of Haematology. 2024-08-09. PMID:39120005. |
in patients presenting with severe hematologic findings, tnf alpha inhibitors are not the treatment of choice, and hematopoietic stem cell transplantation has been shown to be successful in selected cases. |
2024-08-09 |
2024-08-12 |
Not clear |
| Jiaqi Wang, Feiran Lin, Yongxiang Zhou, Yuyi Cong, Sen Yang, Sujuan Wang, Xiaobing Gua. Chemopreventive effect of modified zeng-sheng-ping on oral squamous cell carcinoma by regulating tumor associated macrophages through targeting tnf alpha induced protein 6. BMC complementary medicine and therapies. vol 24. issue 1. 2024-07-28. PMID:39068492. |
chemopreventive effect of modified zeng-sheng-ping on oral squamous cell carcinoma by regulating tumor associated macrophages through targeting tnf alpha induced protein 6. |
2024-07-28 |
2024-08-02 |
Not clear |
| Tianyu Wang, Jinbo Chen, Junliang Wang, Yanyan Zhang, Wei Mao, Quanyong Y. 91 Circulating inflammatory proteins and the risk of age-related macular degeneration: A bidirectional Mendelian randomization study. International immunopharmacology. vol 139. 2024-07-28. PMID:39068753. |
the findings indicated that elevated levels of four circulating inflammatory proteins, including c-c motif chemokine ligand 11 (ccl11), signaling lymphocytic activation molecule family member 1 (slamf1), tnf superfamily member 11 (trance) and vascular endothelial growth factor a (vegf-a) lead to the increased risk of amd, while increased levels of two circulating inflammatory proteins, including fibroblast growth factor 19 (fgf-19) and interleukin 10 receptor subunit alpha (il-10ra), resulted in the decreased risk of amd. |
2024-07-28 |
2024-08-02 |
Not clear |
| Julia Jaroslawska, Ranjini Ghosh Dastidar, Carsten Carlber. In vivo vitamin D target genes interconnect key signaling pathways of innate immunity. PloS one. vol 19. issue 7. 2024-07-23. PMID:39042613. |
a ranking of the 61 target genes by inducibility, basal expression and multiple involvements in the pathways highlighted the genes nfkbia (nfκb inhibitor alpha), nfkbiz, fosl2 (fos like 2, ap1 transcription factor subunit), jdp2 (jun dimerization protein 2), pik3r1 (phosphoinositide-3-kinase regulatory subunit 1), clec7a (c-type lectin domain containing 7a), dusp6 (dual specificity phosphatase 6), ncf2 (neutrophil cytosolic factor 2), plcb1 (phospholipase c beta 1), plcg2 and tnfaip3 (tnf alpha induced protein 3). |
2024-07-23 |
2024-07-26 |
Not clear |
| Nicole Stübiger, Klemens Ruprecht, Uwe Pleye. [Uveitis and multiple sclerosis : Clinical aspects, diagnostics, management and treatment]. Die Ophthalmologie. 2024-07-22. PMID:39037464. |
when selecting the active substance it must be taken into account that tumor necrosis factor (tnf) alpha blockers are contraindicated in patients with ms. |
2024-07-22 |
2024-07-24 |
Not clear |
| Lijiang Wang, Supaporn Kulthinee, Nahiro Yano, Huai Wen, Ling X Zhang, Zachary S S L Saleeba, Na Jin, Ou Chen, Ting C Zha. Gold nanoparticles-conjugation of irisin enhances therapeutic effect by improving cardiac function and attenuating inflammation in sepsis. Molecular diversity. 2024-07-18. PMID:39026117. |
enzyme linked immunosorbent assay (elisa) was conducted to examine release of interleukin 6 (il6) and the tumor necrosis factor (tnf) alpha. |
2024-07-18 |
2024-07-21 |
mouse |
| Georgios Zouris, Dimitrios Stergios Evangelopoulos, Ioannis S Benetos, John Vlami. The Use of TNF-α Inhibitors in Active Ankylosing Spondylitis Treatment. Cureus. vol 16. issue 6. 2024-07-02. PMID:38952586. |
a search was performed in the pubmed database using the following keywords: ("tnf alpha inhibitors" or "anti tnf-a" or "tnf-a inhibitors" or "anti tnf-alpha" or "etanercept " or "golimumab" or "infliximab" or "certolizumab pegol" or "adalimumab") and "ankylosing spondylitis". |
2024-07-02 |
2024-07-04 |
Not clear |
| Kajal Gaba, Parveen Malhotra, Anil Kumar, Pooja Suneja, Amita Suneja Dan. Understanding the Genetic Basis of Celiac Disease: A Comprehensive Review. Cell biochemistry and biophysics. 2024-06-22. PMID:38907939. |
however, present study indicate that most current research predominantly focus on cytokines, specifically the tnf alpha gene. |
2024-06-22 |
2024-06-25 |
Not clear |
| Murillo Duarte-Silva, Rogério Serafim Parra, Marley Ribeiro Feitosa, Viviani Nardini, Sandra Regina Maruyama, José Joaquim Ribeiro da Rocha, Omar Feres, Cristina Ribeiro de Barros Cardos. Leukocyte dysfunction and reduced CTLA-4 expression are associated with perianal Crohn's disease. Clinical and experimental immunology. vol 217. issue 1. 2024-06-20. PMID:38517030. |
however, their pbmc was characterized by decreased il-6 production, while patients with a history of pcd produced higher il-6, il-8, and interferon-γ, along with decreased tumor necrosis factor alpha (tnf). |
2024-06-20 |
2024-06-22 |
human |
| Lisa Kongrat, Arash Maleki, Ploysai Rujkorakarn, Michael J Margolis, Tate Valerio, Yasmin Massoudi, Stephen D Anesi, C Stephen Foste. Outcomes of Intravenous Tocilizumab Treatment for Refractory Pars Planitis. Ocular immunology and inflammation. 2024-05-23. PMID:38781578. |
to evaluate outcomes of intravenous (iv) tocilizumab (tcz) in patients with pars planitis refractory to conventional immunomodulatory therapy and anti-tumor necrosis factor (tnf) alpha agents. |
2024-05-23 |
2024-05-27 |
Not clear |
| Piotr K Krajewski, Łukasz Matusiak, Sascha Ständer, Diamant Thaçi, Jacek C Szepietowski, Henner Zirpe. Risk of cardiovascular disorders in hidradenitis suppurativa patients: a large-scale, propensity-matched global retrospective cohort study. International journal of dermatology. 2024-04-21. PMID:38644522. |
the creation of atherosclerotic plaque is characterized by endothelial dysfunction driven by elevated concentrations of interleukin (il)-1, il-6, and il-18 among others, as well as tumor necrosis factor (tnf) alpha. |
2024-04-21 |
2024-04-24 |
Not clear |
| Laura L Mateu-Arrom, Lluis L Pui. Choosing the right biologic treatment for moderate-to-severe plaque psoriasis: the impact of comorbidities. Expert review of clinical pharmacology. 2024-04-11. PMID:38603464. |
currently, there is a wide range of biological treatments available for moderate to severe psoriasis, including tumor necrosis alpha (tnf) inhibitors, il12/23 inhibitor, il17 inhibitors, and il23 inhibitors. |
2024-04-11 |
2024-04-14 |
Not clear |
| Molly Klimak, Farshid Guila. Genetically engineered macrophages derived from iPSCs for self-regulating delivery of anti-inflammatory biologic drugs. Journal of tissue engineering and regenerative medicine. vol 2024. 2024-04-04. PMID:38571695. |
to develop a macrophage-based therapy to treat chronic inflammation, we engineered a novel induced pluripotent stem cell (ipsc)-derived macrophage capable of delivering soluble tnf receptor 1 (tnfr1), an anti-inflammatory biologic inhibitor of tumor necrosis factor alpha (tnf-α), in an auto-regulated manner in response to tnf-α. |
2024-04-04 |
2024-04-06 |
Not clear |
| Samir Ali Abd El-Kaream, Nabila Gaber Ali Hussein, Sohier Mahmoud El-Kholey, Ahmed Mohammed Abd Elmoez Ibrahim Elhelbaw. Microneedle combined with iontophoresis and electroporation for assisted transdermal delivery of goniothalamus macrophyllus for enhancement sonophotodynamic activated cancer therapy. Scientific reports. vol 14. issue 1. 2024-04-04. PMID:38575628. |
in addition significantly increased apoptotic genes expressions (p53, caspase (3, 9), bax, and tnf alpha) and on the other hand decreased anti- apoptotic (bcl-2) and angiogenic (vegf) genes expressions. |
2024-04-04 |
2024-04-07 |
mouse |
| Yiyi Hu, Yunchuan Li, Haodan Zhu, Dandan Wang, Junming Zhou, Yanxiu Ni, Rongli Guo, Baochao Fan, Bin L. In vitro suppression of porcine epidemic diarrhea virus by Panax notoginseng saponins: assessing antiviral potential. Archives of virology. vol 169. issue 5. 2024-04-02. PMID:38565720. |
pns exerts its anti-pedv activity specifically at the genome replication stage, and mrna-seq analysis demonstrated that treatment with pns resulted in increased expression of various genes, including ifit1 (interferon-induced protein with tetratricopeptide repeats 1), ifit3 (interferon-induced protein with tetratricopeptide repeats 3), cfh (complement factor h), igsf10 (immunoglobulin superfamily member 10), id2 (inhibitor of dna binding 2), spp1 (secreted phosphoprotein 1), plcb4 (phospholipase c beta 4), and fabp4 (fatty acid binding protein 4), but it resulted in decreased expression of il1a (interleukin 1 alpha), tnfrsf19 (tnf receptor superfamily member 19), cdh8 (cadherin 8), ddit3 (dna damage inducible transcript 3), gadd45a (growth arrest and dna damage inducible alpha), ptprg (protein tyrosine phosphatase receptor type g), pck2 (phosphoenolpyruvate carboxykinase 2), and adgra2 (adhesion g protein-coupled receptor a2). |
2024-04-02 |
2024-04-05 |
Not clear |
| Amanda S Pellowe, Michelle J Wu, Tae-Yun Kang, Tracy D Chung, Adrian Ledesma-Mendoza, Erica Herzog, Andre Levchenko, Ian Odell, John Varga, Anjelica L Gonzale. TGFβ1 Drives Integrin Dependent Pericyte Migration and Microvascular Destabilization In Fibrotic Disease. The American journal of pathology. 2024-03-28. PMID:38548268. |
using pro-inflammatory tnf alpha (tnfα) or fibrotic growth factor tgf beta-1 (tgfβ1), human pc inflammatory and fibrotic phenotypes were evaluated by assessing their migration, matrix deposition, integrin expression, and subsequent effects on endothelial dysfunction. |
2024-03-28 |
2024-03-31 |
human |