| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiangang Zheng, Abdul Haseeb, Ziyang Wang, Hejie Wan. Network pharmacology, computational biology integrated surface plasmon resonance technology reveals the mechanism of ellagic acid against rotavirus. Scientific reports. vol 14. issue 1. 2024-03-30. PMID:38555283. |
the results of network pharmacological analysis showed that there were 35 intersection proteins, among which interleukin-1β (il-1β), albumin (alb), nuclear factor kappa-b1 (nf-κb1), toll-like receptor 4 (tlr4), tumor necrosis factor alpha (tnf-α), tumor protein p53 (tp53), recombinant smad family member 3 (samd3), epidermal growth factor (egf) and interleukin-4 (il-4) were potential core targets of ea anti-rv. |
2024-03-30 |
2024-04-02 |
Not clear |
| Yan Zhang, Yu-Shen Yang, Wei-Can Chen, Cong-Mei Wang, He-Fan H. Constructing and Validating a Network of Potential Olfactory Sheathing Cell Transplants Regulating Spinal Cord Injury Progression. Molecular neurobiology. 2023-07-29. PMID:37515671. |
we found that cd4, tp53, rac2, and akt3 differed between vehicle and transplanted groups, suggesting that these genes may play an essential role in the transplantation of olfactory ensheathing cells, while a toll-like receptor signaling pathway was significantly enriched in gene set enrichment analysis, and then, the differences were statistically significant by experimentally verifying the expression of their associated molecules (tlr4, nf-κb, ikkβ, cxcl2, and tnf-α). |
2023-07-29 |
2023-08-14 |
Not clear |
| Truong Quynh Nhu, Hang Bui Thi Bich, Huong Do Thi Thanh, Marie-Louise Scippo, Phuong Nguyen Thanh, Joëlle Quetin-Leclercq, Patrick Kestemon. Psidium guajava L.- dichloromethane and ethyl acetate fractions ameliorate striped catfish (Pangasianodon hypophthalmus) status via immune response, inflammatory, and apoptosis pathways. Fish & shellfish immunology. 2023-05-28. PMID:37245678. |
with regards to the in vivo experiment, the cc fraction of the guava extract could significantly enhance the tlrs-myd88-nf-κb signaling pathway by upregulating its cytokine genes (tlr1, tlr4, myd88, and traf6), following the upregulation of inflammatory (nfκb, tnf, il1β, and il6) and apoptosis (tp53 and casp8) genes 6 h after injection. |
2023-05-28 |
2023-08-14 |
Not clear |
| Joanna Szkandera, Gudrun Absenger, Nadia Dandachi, Peter Regitnig, Sigurd Lax, Michael Stotz, Hellmut Samonigg, Wilfried Renner, Armin Gerge. Analysis of functional germline polymorphisms for prediction of response to anthracycline-based neoadjuvant chemotherapy in breast cancer. Molecular genetics and genomics : MGG. vol 287. issue 9. 2012-11-08. PMID:22903472. |
to elucidate the role of predictive factors on individual's drug response, based on genetic variation, we examined the association between eight germline polymorphisms in genes involved in protection against oxidative stress, apoptosis, oncogenic transformation, proliferation, immune response and dna repair (tp53, nqo1, il6, tlr4 and xrcc1) and the pathological response to anthracycline-based neoadjuvant chemotherapy in 70 patients with breast cancer. |
2012-11-08 |
2023-08-12 |
Not clear |