| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adela Kratochvilova, Lucia Knopfova, Janka Gregorkova, Reinhard Gruber, Eva Janeckova, Yang Chai, Eva Matalov. FasL impacts Tgfb signaling in osteoblastic cells. Cells & development. 2024-06-09. PMID:38810946. |
tgfb subfamily members (tgfb1, tgfb2, tgfb3) represent major components in osteogenic pathways and extracellular matrix. |
2024-06-09 |
2024-06-11 |
Not clear |
| Jose Alejandro Guerrero, Raquel Souto Silva, Izabella Lucas de Abreu Lima, Bianca Cristina Duffles Rodrigues, Breno Rocha Barrioni, Flávio Almeida Amaral, André Petenuci Tabanez, Gustavo Pompermaier Garlet, Diego Alexander Garzon Alvarado, Tarcília Aparecida Silva, Estevam Barbosa de Las Casas, Soraia Macar. Maxillary suture expansion: A mouse model to explore the molecular effects of mechanically-induced bone remodeling. Journal of biomechanics. vol 108. 2021-05-14. PMID:32635995. |
rme yielded increased expression of bone remodeling markers as osteocalcin (ocn), dentin matrix acidic phosphoprotein-1 (dmp1), runt-related transcription factor 2 (runx2), collagen type i alpha 1 (col1a1), alkaline phosphatase (alp), receptor activator of nuclear factor kappa b (rank), receptor activator of nuclear factor kappa b ligand (rankl), osteoprotegerin (opg), cathepsin k (ctsk), matrix metalloproteinases 9 and 13 (mmp9 and 13), transforming growth fator beta 1, 2 and 3 (tgfb 1, tgfb 2 and tgfb3), bone morphogenetic protein 2 (bmp-2), sclerostin (sost), beta-catenin-like protein 1 (ctnnbl) and wnt signaling pathways 3, 3a and 5a (wnt 3, wnt 3a and wnt 5a). |
2021-05-14 |
2023-08-13 |
mouse |
| Rebekah M Samsonraj, Amel Dudakovic, Bushra Manzar, Buer Sen, Allan B Dietz, Simon M Cool, Janet Rubin, Andre J van Wijne. Osteogenic Stimulation of Human Adipose-Derived Mesenchymal Stem Cells Using a Fungal Metabolite That Suppresses the Polycomb Group Protein EZH2. Stem cells translational medicine. vol 7. issue 2. 2019-09-11. PMID:29280310. |
we show that cytod, which may function by redistributing the intracellular location of β-actin (actb), is a potent osteogenic stimulant as reflected by significant increases in alkaline phosphatase activity, extracellular matrix mineralization, and osteoblast-related gene expression (e.g., runx2, alpl, sparc, and tgfb3). |
2019-09-11 |
2023-08-13 |
human |
| Jan Philipp Krüger, Anna-Katharina Ketzmar, Michaela Endres, Axel Pruss, Alberto Siclari, Christian Kap. Human platelet-rich plasma induces chondrogenic differentiation of subchondral progenitor cells in polyglycolic acid-hyaluronan scaffolds. Journal of biomedical materials research. Part B, Applied biomaterials. vol 102. issue 4. 2014-12-15. PMID:24510445. |
progenitor cells in pga-ha scaffolds formed an extracellular matrix rich in proteoglycans and collagen type ii on treatment with prp, but to a lesser extent, than in cultures stimulated with tgfb3. |
2014-12-15 |
2023-08-12 |
human |
| Jan Philipp Krüger, Anna-Katharina Ketzmar, Michaela Endres, Axel Pruss, Alberto Siclari, Christian Kap. Human platelet-rich plasma induces chondrogenic differentiation of subchondral progenitor cells in polyglycolic acid-hyaluronan scaffolds. Journal of biomedical materials research. Part B, Applied biomaterials. vol 102. issue 4. 2014-12-15. PMID:24510445. |
tgfb3 and prp induced the expression of chondrogenic marker genes collagen type ii and ix, aggrecan, and cartilage oligomeric matrix protein in subchondral progenitor cells cultured in pga-ha scaffolds compared with nonstimulated controls. |
2014-12-15 |
2023-08-12 |
human |
| Jan Philipp Krüger, Michaela Endres, Katja Neumann, Thomas Häupl, Christoph Erggelet, Christian Kap. Chondrogenic differentiation of human subchondral progenitor cells is impaired by rheumatoid arthritis synovial fluid. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 28. issue 6. 2010-05-04. PMID:20041492. |
histological staining of proteoglycan and immunostaining of type ii collagen showed that progenitors stimulated with sf from ra donors show significantly reduced cartilage matrix formation compared to progenitors treated with tgfb3 or with sf from normal and oa donors (n = 3, each). |
2010-05-04 |
2023-08-12 |
human |
| Yvonne H Sniekers, Gerjo J V M van Osch, Holger Jahr, Harrie Weinans, Johannes P T M van Leeuwe. Estrogen modulates iodoacetate-induced gene expression in bovine cartilage explants. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 28. issue 5. 2010-04-13. PMID:19953602. |
on day 14, transforming growth factor beta (tgfb)1 and tgfb3 were upregulated, and matrix metalloproteinase (mmp)13 and vegf downregulated. |
2010-04-13 |
2023-08-12 |
cattle |