All Relations between tfeb and Nicotine

Publication Sentence Publish Date Extraction Date Species
Hui-Hui Wu, Jia-Min Du, Peng Liu, Fan-Liang Meng, Yue-Yan Li, Wen-Jing Li, Shuang-Xi Wang, Nai-Li Du, Yan Zheng, Liang Zhang, Hui-Yun Wang, Yi-Ran Liu, Chun-Hong Song, Xi Ni, Ying Li, Guo-Hai S. LDHA contributes to nicotine induced cardiac fibrosis through autophagy flux impairment. International immunopharmacology. vol 136. 2024-06-08. PMID:38850787. nicotine treatment impaired autophagy flux by regulating the ampk/mtor signaling pathway, impeding the nuclear translocation of transcription factor eb (tfeb), and reducing the activity of cathepsin b (ctsb). 2024-06-08 2024-06-11 rat
Huaner Ni, Shuang Xu, Hangwei Chen, Qiuyan Da. Nicotine Modulates CTSS (Cathepsin S) Synthesis and Secretion Through Regulating the Autophagy-Lysosomal Machinery in Atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology. vol 40. issue 9. 2020-10-07. PMID:32640907. western blotting and immunofluorescent staining showed that nicotine inhibited the mtorc1 (mammalian target of rapamycin complex 1) activity, promoted the nuclear translocation of tfeb (transcription factor eb), and upregulated the expression of ctss. 2020-10-07 2023-08-13 Not clear