| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hongyu Niu, Chao Li, Hexin Zhang, Haokun Liu, Chunmei Shang, Yanni Jia, Wuenjiya, Zuhui Li, Aihua Wang, Yaping Jin, Pengfei Li. Androgen synthesis cell-specific CREBZF deficiency alters adrenal cortex steroid secretion and develops behavioral abnormalities in adult male mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 38. issue 9. 2024-05-02. PMID:38696238. |
immunohistochemical staining revealed increased expression of star, cyp11a1, and 17β-hsd3 in the adrenal cortex of crebzf-cko mice, while the expression of ar was significantly reduced. |
2024-05-02 |
2024-05-04 |
mouse |
| Aditya Phadte, Charushila Dhole, Samiksha Hegishte, Vijaya Sarathi, Anurag Lila, Jugal V Gada, Saba Samad Memon, Sneha Arya, Manjiri Karlekar, Virendra Patil, Premlata K Varthakavi, Nalini Shah, Nikhil M Bhagwat, Tushar Bandga. Steroidogenic acute regulatory protein (STAR) deficiency: Our experience and systematic review for phenotype-genotype correlation. Clinical endocrinology. 2024-02-18. PMID:38368602. |
lipoid congenital adrenal hyperplasia (lcah) is caused by mutations in star. |
2024-02-18 |
2024-02-21 |
Not clear |
| Marwa N Atallah, Gamal M Badawy, Fatma S Abdallah, Hend T El-Bor. Assessment of methomyl-induced adrenal gland disruption in rat fetuses and pups: Potential protective effects of propolis supplementation. Journal of experimental zoology. Part A, Ecological and integrative physiology. 2023-12-29. PMID:38155514. |
the results revealed that methomyl exposure, during pregnancy and lactation, induced many histological and ultrastructural changes, caused dna damage and downregulated the expression of steroidogenic acute regulatory (star) and cyp11b2 genes in the adrenal glands of both rat fetuses and pups. |
2023-12-29 |
2023-12-31 |
rat |
| Marwa N Atallah, Gamal M Badawy, Fatma S Abdallah, Hend T El-Bor. Assessment of methomyl-induced adrenal gland disruption in rat fetuses and pups: Potential protective effects of propolis supplementation. Journal of experimental zoology. Part A, Ecological and integrative physiology. 2023-12-29. PMID:38155514. |
interestingly, propolis supplementation demonstrated a remarkable ability to mitigate these deleterious effects and restored the histology and ultrastructure architecture of the adrenal glands of both fetuses and pups, as well as decreased dna damage and upregulated the expression of star and cyp11b2 genes in the adrenal gland of rat fetuses and pups. |
2023-12-29 |
2023-12-31 |
rat |
| Ayman A Bakkar, Abdulaziz Alsaedi, Naglaa M Kamal, Enad Althobaiti, Lujain A Aboulkhair, Abdullah M Almalki, Shaima A Alsalmi, Qaydah Alharthi, Sara A Abosabie, Salma As Abosabi. Lipoid Congenital Adrenal Hyperplasia With a Novel StAR Gene Mutation. Clinical medicine insights. Endocrinology and diabetes. vol 16. 2023-05-31. PMID:37255966. |
lipoid congenital adrenal hyperplasia with a novel star gene mutation. |
2023-05-31 |
2023-08-14 |
Not clear |
| Shahrzad Aghaei, Effat Farrokhi, Javad Saffari-Chaleshtori, Marziyeh Hoseinzadeh, Newsha Molavi, Mahin Hashemipour, Noushin Rostampour, Samira Asgharzadeh, Mohammad Amin Tabatabaiefa. New molecular insights into the A218V variant impact on the steroidogenic acute regulatory protein (STAR) associated with 46, XY disorders of sexual development. Molecular genetics and genomics : MGG. 2023-04-02. PMID:37004560. |
the steroidogenic acute regulatory (star) gene, associated with congenital lipoid adrenal hyperplasia (clah), is included in the targeted gene panel for the dsd diagnosis. |
2023-04-02 |
2023-08-14 |
Not clear |
| Jie Liu, Hong-Mei Dai, Gao-Peng Guang, Wen-Mu Hu, Ping Ji. Clinical and functional analyses of the novel STAR c.558C>A in a patient with classic lipoid congenital adrenal hyperplasia. Frontiers in genetics. vol 14. 2023-02-03. PMID:36733346. |
clinical and functional analyses of the novel star c.558c>a in a patient with classic lipoid congenital adrenal hyperplasia. |
2023-02-03 |
2023-08-14 |
Not clear |
| Wenli Lu, Tingting Zhang, Lidan Zhang, Xueqing Wang, Sheng Lv, Junqi Wang, Lei Ye, Yuan Xiao, Zhiya Dong, Wei Wang, Shuoyue Sun, Chuanyin Li, Ronggui Hu, Guang Ning, Xiaoyu M. Clinical characteristics of a male child with non-classic lipoid congenital adrenal hyperplasia and literature review. Frontiers in endocrinology. vol 13. 2022-11-21. PMID:36407315. |
lipoid congenital adrenal hyperplasia (lcah) is a rare and severe disorder that is caused by mutations in the steroidogenic acute regulatory protein (star). |
2022-11-21 |
2023-08-14 |
Not clear |
| W Q Zheng, Y Duan, B Xiao, L L Liang, Y Xia, Z W Gong, Y Sun, H W Zhang, L S Han, R F Wang, Y Yang, X Zhan, Y G Yu, X F Gu, W J Qi. [Clinical and StAR genetic characteristics of 33 children with congenital lipoid adrenal hyperplasia]. Zhonghua er ke za zhi = Chinese journal of pediatrics. vol 60. issue 10. 2022-10-08. PMID:36207855. |
[clinical and star genetic characteristics of 33 children with congenital lipoid adrenal hyperplasia]. |
2022-10-08 |
2023-08-14 |
Not clear |
| Yan-Jun Wang, Cong Liu, Chuan Xing, Le Zhang, Wan-Feng Xu, Hai-Ying Wang, Fu-Tao Wan. Congenital lipoid adrenal hyperplasia with Graves' disease: A case report. World journal of clinical cases. vol 10. issue 26. 2022-09-26. PMID:36159444. |
congenital adrenal hyperplasia (cah), which is caused by a mutation of the steroidogenic acute regulatory (star) gene. |
2022-09-26 |
2023-08-14 |
Not clear |
| Siham Hussein Subki, Raghad Wadea Mohammed Hussain, Abdulmoein Eid Al-Agh. Congenital lipoid adrenal hyperplasia in a Saudi infant. Endocrinology, diabetes & metabolism case reports. vol 2022. 2022-09-02. PMID:36053179. |
congenital lipoid adrenal hyperplasia (clah) is characterized by a defect in the star protein-encoding gene that attenuates all steroidogenesis pathways. |
2022-09-02 |
2023-08-14 |
Not clear |
| Shogo Harashima, Yuto Yamazaki, Naoki Motomura, Yoshikiyo Ono, Kei Omata, Yuta Tezuka, Ryo Morimoto, Yasuhiro Nakamura, Fumitoshi Satoh, Hiroyoshi Suzuki, Go Eun Kwon, Man Ho Choi, Hironobu Sasan. Phenotype-genotype Correlation in Aldosterone-producing Adenomas Characterized by Intracellular Cholesterol Metabolism. The Journal of steroid biochemistry and molecular biology. 2022-05-09. PMID:35533918. |
therefore, in order to explore these differences, 52 apa cases (kcnj5 mt: n=33, non-kcnj5 mt: n=19; atp1a1: n=3, atp2b3: n=3, cacna1d: n=5, ctnnb1: n=1, tumors without any mutation above: n=7), zona glomerulosa (zg) tissue adjacent to apa and 10 non-pathological adrenal glands (nas) were examined for quantitative histopathological analysis of tumor morphology and immunohistochemical analysis of cholesterol receptors (sr-b1, ldl-r), cholesterol metabolic enzymes (acat1, acat2, hsl, dhcr24, star), and the enzymes required for steroid synthesis (cyp11a1, cyp17a, 3βhsd, cyp11b1, cyp11b2). |
2022-05-09 |
2023-08-13 |
Not clear |
| Guanghui Chen, Can Ai, Fangfang Duan, Yawen Chen, Jiangang Cao, Jinzhi Zhang, Ying Ao, Hui Wan. Low H3K27 acetylation of SF1 in PBMC: a biomarker for prenatal dexamethasone exposure-caused adrenal insufficiency of steroid synthesis in male offspring. Cell biology and toxicology. 2022-03-05. PMID:35246761. |
we found the adrenal morphological and functional changes of pde male offspring rats before and after birth, which were mainly performed as the decreased serum corticosterone concentration, steroidogenic acute regulatory (star) protein expression, and histone 3 lysine 27 acetylation (h3k27ac) level of steroidogenic factor 1 (sf1) promoter region and its expression. |
2022-03-05 |
2023-08-13 |
rat |
| Gabriela P Finkielstain, Ana Vieites, Ignacio Bergadá, Rodolfo A Re. Disorders of Sex Development of Adrenal Origin. Frontiers in endocrinology. vol 12. 2022-01-06. PMID:34987475. |
lipoid congenital adrenal hyperplasia due to star defects, and cytochrome p450scc and p450c17 deficiencies cause dsd in 46,xy newborns. |
2022-01-06 |
2023-08-13 |
Not clear |
| Kyle A Sullivan, Corena V Grant, Kelley R Jordan, Karl Obrietan, Leah M Pyte. Paclitaxel chemotherapy disrupts behavioral and molecular circadian clocks in mice. Brain, behavior, and immunity. vol 99. 2021-12-11. PMID:34563619. |
furthermore, paclitaxel disrupted circulating corticosterone rhythms in dd by elevating its levels across a 24-hour cycle, which correlated with blunted amplitudes of arntl, nr1d1, per1, and star rhythms in the adrenal glands. |
2021-12-11 |
2023-08-13 |
mouse |
| Daniel P Fudulu, George Horn, Georgina Hazell, Anne-Marie Lefrançois-Martinez, Antoine Martinez, Gianni D Angelini, Stafford L Lightman, Francesca Spig. Co-culture of monocytes and zona fasciculata adrenal cells: An in vitro model to study the immune-adrenal cross-talk. Molecular and cellular endocrinology. vol 526. 2021-10-07. PMID:33571577. |
addition of lps to co-cultures of atc7 and thp1 significantly decreased the expression of key adrenal steroidogenic enzymes (including star and dax-1), and this was also found in atc7 cells treated with pro-inflammatory cytokines. |
2021-10-07 |
2023-08-13 |
human |
| Zheng He, Jinzhi Zhang, Guanghui Chen, Jiangang Cao, Yawen Chen, Can Ai, Hui Wan. H19/let-7 axis mediates caffeine exposure during pregnancy induced adrenal dysfunction and its multi-generation inheritance. The Science of the total environment. vol 792. 2021-09-02. PMID:34465058. |
meanwhile, the expression of fetal adrenal gr, dnmt3a/3b, mirna let-7c increased while those of ctcf, h19, and star decreased, and the total methylation rate of the h19 promoter region was enhanced. |
2021-09-02 |
2023-08-13 |
rat |
| Meenal Garg, Vasundhara Chugh, Sunil Dutt Sharma, Prashant Mitharwal, Ankit Mangl. Non-classical lipoid adrenal hyperplasia presenting as hypoglycemic seizures. Journal of pediatric endocrinology & metabolism : JPEM. vol 33. issue 11. 2021-08-27. PMID:32841165. |
mutations in the steroidogenic acute regulatory protein (star) gene produce lipoid congenital adrenal hyperplasia (lcah) which usually presents in the infantile period with severe symptoms of adrenal insufficiency. |
2021-08-27 |
2023-08-13 |
Not clear |
| Raíssa D Ventura, Amanda S Chaves, Nathalia S Magalhães, Florencia B Gonzalez, Maria Florencia Pacini, Ana Rosa Pérez, Patrícia M R Silva, Marco A Martins, Vinicius F Carvalh. Activation of PPARγ reduces N-acetyl-cysteine -induced hypercorticoidism by down-regulating MC2R expression into adrenal glands. Free radical biology & medicine. vol 156. 2021-06-18. PMID:32574682. |
rosiglitazone also significantly reversed the nac-induced increase in the mc2r expression in adrenal, but not steroidogenic acute regulatory protein (star). |
2021-06-18 |
2023-08-13 |
mouse |
| Lorna I F Smith, Zidong Zhao, Jamie Walker, Stafford Lightman, Francesca Spig. Activation and expression of endogenous CREB-regulated transcription coactivators (CRTC) 1, 2 and 3 in the rat adrenal gland. Journal of neuroendocrinology. vol 33. issue 1. 2021-06-15. PMID:33314405. |
plasma acth and corticosterone (cort) were measured and the adrenal glands were processed for measurement of protein by western immunoblotting, rna by a quantitative reverse transcriptase-polymerase chain reaction and association of crtc2 and crtc3 with the star promoter by chromatin immunoprecipitation. |
2021-06-15 |
2023-08-13 |
rat |