| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenjing Liu, Shanshan Ming, Xiaobing Zhao, Xin Zhu, Yuxiang Gon. Developmental expression of high-mobility group box 1 (HMGB1) in the mouse cochlea. European journal of histochemistry : EJH. vol 67. issue 3. 2023-09-05. PMID:37667832. |
in addition, hmgb1 was expressed in the greater epithelial ridge (ger) and supporting cells of the organ of corti, as validated by the supporting cell marker sox2 at p1 and p8. |
2023-09-05 |
2023-09-07 |
mouse |
| Lu M Yang, Kathryn S E Cheah, Sung-Ho Huh, David M Ornit. Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner. PLoS genetics. vol 15. issue 7. 2019-12-17. PMID:31276493. |
however, whether fgf20-fgfr1 signaling is required during specification or differentiation, and how it interacts with the transcription factor sox2, also important for hair cell and supporting cell development, has been a topic of debate. |
2019-12-17 |
2023-08-13 |
mouse |
| Lu M Yang, Kathryn S E Cheah, Sung-Ho Huh, David M Ornit. Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner. PLoS genetics. vol 15. issue 7. 2019-12-17. PMID:31276493. |
sox2 and fgf20 interact to regulate organ of corti hair cell and supporting cell development in a spatially-graded manner. |
2019-12-17 |
2023-08-13 |
mouse |
| Lingling Jiang, Ran Jin, Jincao Xu, Yubin Ji, Meiguang Zhang, Xuebo Zhang, Xinwen Zhang, Zhongming Han, Shaoju Zen. Hair cell regeneration or the expression of related factors that regulate the fate specification of supporting cells in the cochlear ducts of embryonic and posthatch chickens. Hearing research. vol 332. 2016-12-13. PMID:26688175. |
these data and the obtained dynamic changes of the cells labeled for brdu, sox2, atoh1/math1, pv or p27(kip1) are useful for understanding supporting cell behaviors and their fate specification during hair cell regeneration. |
2016-12-13 |
2023-08-13 |
chicken |
| Cynthia L Chow, Weixiang Guo, Parul Trivedi, Xinyu Zhao, Samuel P Gubbel. Characterization of a unique cell population marked by transgene expression in the adult cochlea of nestin-CreER(T2)/tdTomato-reporter mice. The Journal of comparative neurology. vol 523. issue 10. 2016-03-15. PMID:25611038. |
all cells colocalized with the stem cell and cochlear-supporting-cell marker sox2 as well as the supporting cell and schwann cell marker sox10; however, they did not colocalize with the schwann cell marker krox20, spiral ganglion marker nf200, nor glial fibrillary acidic acid (gfap)-expressing supporting cell marker. |
2016-03-15 |
2023-08-13 |
mouse |
| Bradley J Walters, Zhiyong Liu, Mark Crabtree, Emily Coak, Brandon C Cox, Jian Zu. Auditory hair cell-specific deletion of p27Kip1 in postnatal mice promotes cell-autonomous generation of new hair cells and normal hearing. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 47. 2015-01-19. PMID:25411503. |
indeed, hc-specific p27cko results in proliferation of these cells without the upregulation of the supporting cell or progenitor cell proteins, prox1 or sox2, suggesting that they remain hcs. |
2015-01-19 |
2023-08-13 |
mouse |
| Joseph C Burns, James J Yoo, Anthony Atala, John D Jackso. MYC gene delivery to adult mouse utricles stimulates proliferation of postmitotic supporting cells in vitro. PloS one. vol 7. issue 10. 2013-05-06. PMID:23119091. |
transient expression of the induced pluripotency transcription factors, oct3/4, klf4, sox2, and c-myc reprograms fibroblasts into neural progenitors under neural-promoting culture conditions, so as a first step, we explored whether ectopic expression of these factors can reverse supporting cell quiescence in whole organ cultures of adult mouse utricles. |
2013-05-06 |
2023-08-12 |
mouse |
| Joseph C Burns, James J Yoo, Anthony Atala, John D Jackso. MYC gene delivery to adult mouse utricles stimulates proliferation of postmitotic supporting cells in vitro. PloS one. vol 7. issue 10. 2013-05-06. PMID:23119091. |
co-infection of utricles with adenoviral vectors separately encoding oct3/4, klf4, sox2, and the degradation-resistant t58a mutant of c-myc (c-myct58a) triggered significant levels of supporting cell s-phase entry as assessed by continuous brdu labeling. |
2013-05-06 |
2023-08-12 |
mouse |
| David H Nichols, Sarah Pauley, Israt Jahan, Kirk W Beisel, Kathleen J Millen, Bernd Fritzsc. Lmx1a is required for segregation of sensory epithelia and normal ear histogenesis and morphogenesis. Cell and tissue research. vol 334. issue 3. 2009-03-11. PMID:18985389. |
two supporting cell marker proteins, sox2 and prox1, also differ in their cellular distribution between the base and the apex. |
2009-03-11 |
2023-08-12 |
Not clear |