| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masaaki Nishihara, Keisuke Shinohara, Shota Ikeda, Tomohiko Akahoshi, Hiroyuki Tsutsu. Impact of sympathetic hyperactivity induced by brain microglial activation on organ damage in sepsis with chronic kidney disease. Journal of intensive care. vol 12. issue 1. 2024-09-02. PMID:39223624. |
activation of microglia in the paraventricular nucleus of the hypothalamus (pvn) has been implicated in sna. |
2024-09-02 |
2024-09-05 |
Not clear |
| Masaaki Nishihara, Ko Takesue, Yoshitaka Hirook. Olmesartan combined with renal denervation reduces blood pressure in association with sympatho-inhibitory and aldosterone-reducing effects in hypertensive mice with chronic kidney disease. Clinical and experimental hypertension (New York, N.Y. : 1993). vol 41. issue 3. 2019-04-22. PMID:29694249. |
oxidative stress in the hypothalamus increases sna in ht. |
2019-04-22 |
2023-08-13 |
mouse |
| Masaaki Nishihara, Ko Takesue, Yoshitaka Hirook. Olmesartan combined with renal denervation reduces blood pressure in association with sympatho-inhibitory and aldosterone-reducing effects in hypertensive mice with chronic kidney disease. Clinical and experimental hypertension (New York, N.Y. : 1993). vol 41. issue 3. 2019-04-22. PMID:29694249. |
in the present study, we examined whether combination therapy with olm and rdn reduces both sna by decreasing oxidative stress in the hypothalamus and raas activity in hypertensive mice with ckd. |
2019-04-22 |
2023-08-13 |
mouse |
| Jing Sun, Xing-Sheng Ren, Ying Kang, Hang-Bing Dai, Lei Ding, Ning Tong, Guo-Qing Zhu, Ye-Bo Zho. Intermedin in Paraventricular Nucleus Attenuates Sympathoexcitation and Decreases TLR4-Mediated Sympathetic Activation via Adrenomedullin Receptors in Rats with Obesity-Related Hypertension. Neuroscience bulletin. vol 35. issue 1. 2019-04-09. PMID:30276527. |
in this study, we investigated the effects of imd in the paraventricular nucleus (pvn) of the hypothalamus on sympathetic nerve activity (sna), and lipopolysaccharide (lps)-induced sympathetic activation in obesity-related hypertensive (oh) rats induced by a high-fat diet for 12 weeks. |
2019-04-09 |
2023-08-13 |
rat |
| Dillon F Da Fonte, Lei Xing, Myy Mikwar, Vance L Trudea. Secretoneurin-A inhibits aromatase B (cyp19a1b) expression in female goldfish (Carassius auratus) radial glial cells. General and comparative endocrinology. vol 257. 2018-07-23. PMID:28487180. |
five hours following intracerebroventricular injection of 0.2ng/g sna cyp19a1b mrna levels were decreased by 86% (p<0.05) in the hypothalamus and by 88% (p<0.05) in the telencephalon. |
2018-07-23 |
2023-08-13 |
human |
| Priscila A Cassaglia, Zhigang Shi, Virginia L Brook. Insulin increases sympathetic nerve activity in part by suppression of tonic inhibitory neuropeptide Y inputs into the paraventricular nucleus in female rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 311. issue 1. 2017-07-24. PMID:27122366. |
following binding to receptors in the arcuate nucleus (arcn), insulin increases sympathetic nerve activity (sna) and baroreflex control of sna via a pathway that includes the paraventricular nucleus of the hypothalamus (pvn). |
2017-07-24 |
2023-08-13 |
rat |
| Priscila A Cassaglia, Zhigang Shi, Baoxin Li, Wagner L Reis, Nicholas M Clute-Reinig, Javier E Stern, Virginia L Brook. Neuropeptide Y acts in the paraventricular nucleus to suppress sympathetic nerve activity and its baroreflex regulation. The Journal of physiology. vol 592. issue 7. 2014-12-01. PMID:24535439. |
in chloralose-anaesthetized female rats, nanoinjection of npy into the paraventricular nucleus of the hypothalamus (pvn) dose-dependently suppressed lumbar sna (lsna) and its baroreflex regulation, and these effects were blocked by prior inhibition of npy y1 or y5 receptors. |
2014-12-01 |
2023-08-12 |
rat |
| Robert Frithiof, Tao Xing, Michael J McKinley, Clive N May, Rohit Ramchandr. Intracarotid hypertonic sodium chloride differentially modulates sympathetic nerve activity to the heart and kidney. American journal of physiology. Regulatory, integrative and comparative physiology. vol 306. issue 8. 2014-06-06. PMID:24523342. |
the changes in map and renal sna were completely abolished by microinjection of the gaba agonist muscimol (5 mm, 500 nl each side) into the paraventricular nucleus of the hypothalamus (pvn). |
2014-06-06 |
2023-08-12 |
Not clear |
| Brittany S Luckett, Jennifer L Frielle, Lawrence Wolfgang, Sean D Stocke. Arcuate nucleus injection of an anti-insulin affibody prevents the sympathetic response to insulin. American journal of physiology. Heart and circulatory physiology. vol 304. issue 11. 2013-07-29. PMID:23542919. |
accumulating evidence suggests that insulin acts within the hypothalamus to alter sympathetic nerve activity (sna) and baroreflex function. |
2013-07-29 |
2023-08-12 |
rat |
| Rohit Ramchandra, Sally G Hood, Robert Frithiof, Michael J McKinley, Clive N Ma. The role of the paraventricular nucleus of the hypothalamus in the regulation of cardiac and renal sympathetic nerve activity in conscious normal and heart failure sheep. The Journal of physiology. vol 591. issue 1. 2013-06-13. PMID:22615431. |
the paraventricular nucleus of the hypothalamus (pvn) plays a major role in central cardiovascular and volume control, and has been implicated in controlling sympathetic nerve activity (sna) during volume expansion and in heart failure (hf). |
2013-06-13 |
2023-08-12 |
Not clear |
| Débora S A Colombari, Eduardo Colombari, Andre H Freiria-Oliveira, Vagner R Antunes, Song T Yao, Charles Hindmarch, Alastair V Ferguson, Mark Fry, David Murphy, Julian F R Pato. Switching control of sympathetic activity from forebrain to hindbrain in chronic dehydration. The Journal of physiology. vol 589. issue Pt 18. 2012-05-25. PMID:21708906. |
in euhydrated (eh) rats, systemic application of the at(1) receptor antagonist losartan and subsequent pre-collicular transection (to remove the hypothalamus) significantly reduced thoracic (t)sna. |
2012-05-25 |
2023-08-12 |
rat |
| Glenn M Toney, Sean D Stocke. Hyperosmotic activation of CNS sympathetic drive: implications for cardiovascular disease. The Journal of physiology. vol 588. issue Pt 18. 2011-01-19. PMID:20603334. |
in this brief review we emphasize recent findings from several laboratories, including our own, which demonstrate that neurons of the forebrain organum vasculosum laminae terminalis (ovlt) play a pivotal role in triggering hyperosmotic activation of sna by recruiting neurons in specific regions of the hypothalamus, brainstem and spinal cord. |
2011-01-19 |
2023-08-12 |
mouse |
| Megan E Bardgett, John J McCarthy, Sean D Stocke. Glutamatergic receptor activation in the rostral ventrolateral medulla mediates the sympathoexcitatory response to hyperinsulinemia. Hypertension (Dallas, Tex. : 1979). vol 55. issue 2. 2010-02-22. PMID:20065145. |
western blot analysis showed that insulin receptor expression is significantly lower in the rvlm than the hypothalamus, and direct microinjection of insulin into the rvlm did not significantly increase lumbar sna. |
2010-02-22 |
2023-08-12 |
rat |
| Harold D Schultz, Yu Long L. Carotid body function in heart failure. Respiratory physiology & neurobiology. vol 157. issue 1. 2007-07-12. PMID:17374517. |
in addition, impaired function of no in the paraventricular nucleus of the hypothalamus participates in the increased sna response to cb chemoreceptor activation. |
2007-07-12 |
2023-08-12 |
Not clear |
| Jaap A Joles, Hein A Kooman. Causes and consequences of increased sympathetic activity in renal disease. Hypertension (Dallas, Tex. : 1979). vol 43. issue 4. 2004-08-10. PMID:14981063. |
increased sna in renal disease may be sustained because a state of no-ang ii unbalance is also present in the hypothalamus. |
2004-08-10 |
2023-08-12 |
Not clear |
| C J Madden, S F Morriso. Excitatory amino acid receptors in the dorsomedial hypothalamus mediate prostaglandin-evoked thermogenesis in brown adipose tissue. American journal of physiology. Regulatory, integrative and comparative physiology. vol 286. issue 2. 2004-02-27. PMID:14563660. |
microinjection of pge2 (170 pmol/60 nl) into the medial preoptic area of the hypothalamus in urethane-chloralose-anesthetized, artificially ventilated rats increased brown adipose tissue (bat) sympathetic nerve activity (sna; +207 +/- 18% of control), bat temperature (1.5 +/- 0.2 degrees c), expired co2 (0.9 +/- 0.1%), heart rate (hr; 106 +/- 12 beats/min), and mean arterial pressure (22 +/- 4 mmhg). |
2004-02-27 |
2023-08-12 |
rat |