| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohamed K Hankir, Christelle Le Fol. Central nervous system pathways targeted by amylin in the regulation of food intake. Biochimie. 2024-10-19. PMID:39426704. |
in this review, we discuss the evidence derived from preclinical studies showing that amylin and the related peptide salmon calcitonin (sct) directly or indirectly target genetically distinct neurons in the caudal hindbrain (nucleus tractus solitarius and area postrema), rostral hindbrain (lateral parabrachial nucleus), midbrain (lateral dorsal tegmentum and ventral tegmental area) and hypothalamus (arcuate nucleus and parasubthalamic nucleus) via activation of amylin and/or calcitonin receptors. |
2024-10-19 |
2024-10-22 |
Not clear |
| Lavinia Boccia, Tito Borner, Misgana Y Ghidewon, Patricia Kulka, Chiara Piffaretti, Sarah A Doebley, Bart C De Jonghe, Harvey J Grill, Thomas A Lutz, Christelle Le Fol. Hypophagia induced by salmon calcitonin, but not by amylin, is partially driven by malaise and is mediated by CGRP neurons. Molecular metabolism. 2022-01-29. PMID:35091058. |
amylin and sct act centrally to reduce food intake by activating neurons in the area postrema (ap) that project to the lateral parabrachial nucleus (lpbn). |
2022-01-29 |
2023-08-13 |
Not clear |
| Lavinia Boccia, Christelle Le Foll, Thomas A Lut. Noradrenaline signaling in the LPBN mediates amylin's and salmon calcitonin's hypophagic effect in male rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 34. issue 11. 2021-04-27. PMID:32985027. |
amylin and its long acting analog sct (salmon calcitonin) exert their anorectic actions primarily by directly activating neurons located in the area postrema (ap). |
2021-04-27 |
2023-08-13 |
rat |
| Lynda Whiting, James E McCutcheon, Christina N Boyle, Mitchell F Roitman, Thomas A Lut. The area postrema (AP) and the parabrachial nucleus (PBN) are important sites for salmon calcitonin (sCT) to decrease evoked phasic dopamine release in the nucleus accumbens (NAc). Physiology & behavior. vol 176. 2018-03-08. PMID:28342771. |
the pancreatic hormone amylin and its agonist salmon calcitonin (sct) act via the area postrema (ap) and the lateral parabrachial nucleus (pbn) to reduce food intake. |
2018-03-08 |
2023-08-13 |
rat |
| Lynda Whiting, James E McCutcheon, Christina N Boyle, Mitchell F Roitman, Thomas A Lut. The area postrema (AP) and the parabrachial nucleus (PBN) are important sites for salmon calcitonin (sCT) to decrease evoked phasic dopamine release in the nucleus accumbens (NAc). Physiology & behavior. vol 176. 2018-03-08. PMID:28342771. |
the area postrema (ap) and the parabrachial nucleus (pbn) are important sites for salmon calcitonin (sct) to decrease evoked phasic dopamine release in the nucleus accumbens (nac). |
2018-03-08 |
2023-08-13 |
rat |
| Stephan W Barth, Thomas Riediger, Thomas A Lutz, Gerhard Rechkemme. Peripheral amylin activates circumventricular organs expressing calcitonin receptor a/b subtypes and receptor-activity modifying proteins in the rat. Brain research. vol 997. issue 1. 2004-03-29. PMID:14715154. |
the pancreatic hormone amylin (amy) and the amy-receptor-agonist salmon-calcitonin (sct) reduce short-term food-intake after binding to the area postrema (ap), a circumventricular organ (cvo) lacking blood-brain-barrier characteristics. |
2004-03-29 |
2023-08-12 |
rat |
| Stephan W Barth, Thomas Riediger, Thomas A Lutz, Gerhard Rechkemme. Differential effects of amylin and salmon calcitonin on neuropeptide gene expression in the lateral hypothalamic area and the arcuate nucleus of the rat. Neuroscience letters. vol 341. issue 2. 2003-05-15. PMID:12686383. |
the pancreatic peptide hormone amylin (amy) and the amy receptor agonist salmon calcitonin (sct) reduce short-term food intake in rats primarily by activating neurons located in the circumventricular area postrema. |
2003-05-15 |
2023-08-12 |
rat |