| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alon Lai, Denise Iliff, Kashaf Zaheer, Jennifer Gansau, Damien M Laudier, Venetia Zachariou, James C Iatridi. Annulus Fibrosus Injury Induces Acute Neuroinflammation and Chronic Glial Response in Dorsal Root Ganglion and Spinal Cord-An In Vivo Rat Discogenic Pain Model. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339040. |
this study used an in vivo rat annulus fibrosus (af) injury-driven discogenic pain model to investigate the acute and chronic changes in ivd degeneration and spinal inflammation, as well as sensitization, inflammation, and remodeling in dorsal root ganglion (drg) and spinal cord (sc) dorsal horn. |
2024-02-10 |
2024-02-12 |
rat |
| b' Marija Juri\\xc4\\x87, Marta Balog, Vedrana Ivi\\xc4\\x87, Maria Bo\\xc5\\xa1kovi\\xc4\\x87, Benjamin Benzon, Anita Racetin, Katarina Vukojevi\\xc4\\x87, Ivana Bo\\xc4\\x8dina, Nives Kevi\\xc4\\x87, Ivana Restovi\\xc4\\x87, K\\xc3\\xa1lm\\xc3\\xa1n F Sz\\xc5\\xb1cs, R\\xc3\\xb3bert G\\xc3\\xa1sp\\xc3\\xa1r, Marija Heffer, Sandor G Vari, Natalija Filipovi\\xc4\\x8. Increased expression of dendrin in the dorsal horn of the spinal cord during stress is regulated by sex hormones. Neuropeptides. vol 86. 2021-11-12. PMID:33524899.' |
in the sc, dendrin expression was prominent in superficial laminae of the dorsal horn and lamina x (central canal). |
2021-11-12 |
2023-08-13 |
rat |
| b' Marija Juri\\xc4\\x87, Marta Balog, Vedrana Ivi\\xc4\\x87, Maria Bo\\xc5\\xa1kovi\\xc4\\x87, Benjamin Benzon, Anita Racetin, Katarina Vukojevi\\xc4\\x87, Ivana Bo\\xc4\\x8dina, Nives Kevi\\xc4\\x87, Ivana Restovi\\xc4\\x87, K\\xc3\\xa1lm\\xc3\\xa1n F Sz\\xc5\\xb1cs, R\\xc3\\xb3bert G\\xc3\\xa1sp\\xc3\\xa1r, Marija Heffer, Sandor G Vari, Natalija Filipovi\\xc4\\x8. Increased expression of dendrin in the dorsal horn of the spinal cord during stress is regulated by sex hormones. Neuropeptides. vol 86. 2021-11-12. PMID:33524899.' |
co-localization with the α-d-galactosyl-specific isolectin b4 (ib4) in central projections of the drg neurons in the dorsal horn of the sc was 7.43 ± 3.36%, while with the calcitonin gene-related peptide (cgrp) was 8.47 ± 4.45%. |
2021-11-12 |
2023-08-13 |
rat |
| Xiaoming Liu, Hongjun Liu, Lihua Dai, Bingjie Ma, Ke M. CXCR4 antagonist AMD3100 elicits analgesic effect and restores the GlyRα3 expression against neuropathic pain. Journal of pain research. vol 10. 2020-10-01. PMID:28919816. |
this study explored the distribution and function of cxcr4 in spinal cord (sc) dorsal horn (dh) in a rat l5 spinal nerve ligation (snl) model. |
2020-10-01 |
2023-08-13 |
rat |
| Jo Perry, Ann Green, Sally Singh, Paul Watso. A randomised, independent groups study investigating the sympathetic nervous system responses to two manual therapy treatments in patients with LBP. Manual therapy. vol 20. issue 6. 2017-02-09. PMID:25920338. |
the results support the sympatho-excitatory responses seen in normative studies but challenge the assumption that normative and patient populations are analogous with respect to the magnitude of effect observed and suggest that sc responses may be a feasible, proxy method of detecting dorsal horn sensitisation and neuro-plastic adaptations occurring in the presence of lbp. |
2017-02-09 |
2023-08-13 |
human |
| Yunuen Moreno-López, Jimena Pérez-Sánchez, Guadalupe Martínez-Lorenzana, Miguel Condés-Lara, Gerardo Rojas-Pilon. Cortical presynaptic control of dorsal horn C-afferents in the rat. PloS one. vol 8. issue 7. 2014-04-01. PMID:23935924. |
in anaesthetized male wistar rats, we analyzed the effects of sensorimotor cortex activation on post tetanic potentiation (ptp) and the paired pulse ratio (ppr) of dorsal horn field potentials evoked by c-fiber stimulation in the sural (su) and sciatic (sc) nerves. |
2014-04-01 |
2023-08-12 |
rat |
| A G Mensah-Nyagan, C Kibaly, V Schaeffer, C Venard, L Meyer, C Patte-Mensa. Endogenous steroid production in the spinal cord and potential involvement in neuropathic pain modulation. The Journal of steroid biochemistry and molecular biology. vol 109. issue 3-5. 2008-08-06. PMID:18434133. |
indeed, anatomical, cellular and biochemical investigations have shown that the sc dorsal horn (dh), a pivotal structure in nociception, contains various active steroidogenic enzymes such as cytochrome p450side-chain-cleavage, cytochrome p450c17, 3beta-hydroxysteroid dehydrogenase, 5alpha-reductase and 3alpha-hydroxysteroid oxido-reductase. |
2008-08-06 |
2023-08-12 |
Not clear |
| Meng-Ling Chen, Chun Cheng, Qing-Shan Lv, Zhi-Qin Guo, Ying Gao, Shang-Feng Gao, Xin Li, Shu-Qiong Niu, Shu-Xian Shi, Ai-Guo She. Altered gene expression of NIDD in dorsal root ganglia and spinal cord of rats with neuropathic or inflammatory pain. Journal of molecular histology. vol 39. issue 2. 2008-07-03. PMID:17899403. |
it was found that nidd mrna was predominantly expressed in nociceptive primary neurons and in neurons of the spinal dorsal horn (dh) and the number of nidd-positive neurons in the corresponding drg or sc increased significantly following induction of chronic hyperalgesia. |
2008-07-03 |
2023-08-12 |
rat |
| Christine Patte-Mensah, Cherkaouia Kibaly, Domitille Boudard, Véronique Schaeffer, Aurélie Béglé, Simona Saredi, Laurence Meyer, Ayikoe G Mensah-Nyaga. Neurogenic pain and steroid synthesis in the spinal cord. Journal of molecular neuroscience : MN. vol 28. issue 1. 2006-06-27. PMID:16632873. |
in particular, an active form of cytochrome p450 sidechain cleavage (p450scc) has been localized in sensory networks of the rat sc dorsal horn (dh). |
2006-06-27 |
2023-08-12 |
rat |
| Christine Patte-Mensah, Vincent Kappes, Marie-José Freund-Mercier, Kazuyoshi Tsutsui, Ayikoe G Mensah-Nyaga. Cellular distribution and bioactivity of the key steroidogenic enzyme, cytochrome P450side chain cleavage, in sensory neural pathways. Journal of neurochemistry. vol 86. issue 5. 2003-11-12. PMID:12911631. |
p450scc-immunoreactive cells were localized in dorsal root ganglia (drg), spinal cord (sc) dorsal horn, nociceptive supraspinal nuclei (ssn) and somatosensory cortex. |
2003-11-12 |
2023-08-12 |
rat |
| Masayoshi Tsuruoka, Young-Chang Park Arai, Hirofumi Nomura, Kiyo Matsutani, William D Willi. Unilateral hindpaw inflammation induces bilateral activation of the locus coeruleus and the nucleus subcoeruleus in the rat. Brain research bulletin. vol 61. issue 2. 2003-09-02. PMID:12831996. |
several lines of evidence have shown that unilateral hindpaw inflammation produces activation of the locus coeruleus (lc) and the nucleus subcoeruleus (sc), resulting in descending modulation of nociceptive processing in the dorsal horn. |
2003-09-02 |
2023-08-12 |
rat |
| J M Naciff, M A Kaetzel, M M Behbehani, J R Dedma. Differential expression of annexins I-VI in the rat dorsal root ganglia and spinal cord. The Journal of comparative neurology. vol 368. issue 3. 1996-10-23. PMID:8725344. |
in the drg, annexin v is expressed in relatively high concentrations in small sensory neurons in contrast to the sc, where it is expressed mainly by ependymal cells and by small-diameter axons located in the superficial laminae of the dorsal horn areas. |
1996-10-23 |
2023-08-12 |
rat |
| P Rousselot, D A Poulain, D T Theodosi. Ultrastructural visualization and neurochemical characterization of spinal projections of primary sensory afferents from the nipple: combined use of transganglionic transport of HRP-WGA and glutamate immunocytochemistry. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 42. issue 1. 1994-01-26. PMID:8263323. |
after sc injection of tracer into the nipple of lactating rats and reaction with tetramethylbenzidine stabilized with diaminobenzidene (tmb-dab) or dab and cobalt (tmb-dab-co), we found labeled terminals in the internal part of the first two layers of the dorsal horn where they formed axodendritic synapses and, at times, central elements of glomeruli, synaptic complexes believed to be involved in the integration of sensory messages. |
1994-01-26 |
2023-08-12 |
rat |
| H Pérez, A Hernández, S Ruiz, C Paeile, R Soto-Moyan. Long-term effects of neonatal capsaicin on C-fiber excitability and dorsal horn C-input processing in the rat. Brain research bulletin. vol 32. issue 6. 1993-12-14. PMID:8221167. |
the effects of neonatal capsaicin treatment (50 mg/kg, sc, at day 2 of postnatal life) on c-fiber excitability and dorsal horn c-input processing were studied through recording of a c-fiber-evoked spinal flexor reflex in 55-60-day-old rats, anesthetized with urethane (1.1 g/kg, ip) and spinalized at th9-10. |
1993-12-14 |
2023-08-12 |
rat |
| G Z Zhao, R Y Liu, Z Q Zha. Inhibition of formalin-induced responses of spinal dorsal horn neurons by stimulation of lateral reticular nucleus in rats. Zhongguo yao li xue bao = Acta pharmacologica Sinica. vol 14. issue 3. 1993-12-08. PMID:8237391. |
the effects of stimulation of the lateral reticular nucleus (lrn) on responses of spinal dorsal horn neurons produced by formalin (5%, 50 microliters, sc) were investigated. |
1993-12-08 |
2023-08-12 |
rat |
| K A Sluka, K N Westlun. Spinal projections of the locus coeruleus and the nucleus subcoeruleus in the Harlan and the Sasco Sprague-Dawley rat. Brain research. vol 579. issue 1. 1992-08-10. PMID:1623408. |
the sc has a major projection to the dorsal horn in the harlan rats while cells in the sc were predominantly labeled following ventral horn injection in the sasco rats. |
1992-08-10 |
2023-08-11 |
rat |
| J C Holstege, C M Bonger. Ultrastructural aspects of the coeruleo-spinal projection. Progress in brain research. vol 88. 1992-06-16. PMID:1687617. |
on the few data available at present it is concluded that in the spinal superficial dorsal horn, most terminals derived from the area of the lc and sc are na and establish conventional synapses. |
1992-06-16 |
2023-08-11 |
rat |
| J C Holstege, C M Bonger. Ultrastructural aspects of the coeruleo-spinal projection. Progress in brain research. vol 88. 1992-06-16. PMID:1687617. |
in the superficial dorsal horn, terminals derived from the area of the lc and sc were identified at the ultrastructural level in two studies, one using the anterograde degeneration technique in opossum, the other (presented in this chapter) using wga-hrp anterograde tracing in rat. |
1992-06-16 |
2023-08-11 |
rat |
| C Baleydier, F Mauguier. Projections of the ascending somesthetic pathways to the cat superior colliculus visualized by the horseradish peroxidase technique. Experimental brain research. vol 31. issue 1. 1978-06-12. PMID:639909. |
following hrp injection in one sc, marked neurons were found in the contralateral dorsal horn and in the contralateral dorsal column nuclei, mainly the cuneate nucleus. |
1978-06-12 |
2023-08-11 |
cat |