All Relations between sarm1 and \u03b1-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
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Misaki Morishita, Shinji Matsud. SARM1 is essential for NMDA receptor-dependent endocytosis of AMPA receptors in hippocampal neurons. Neuroscience research. 2024-09-30. PMID:39349221. |
however, overexpression of sarm1, which lacks the mitochondrial transport signal, in the sarm1-knocked-down neurons did not restore nmda-dependent ampa receptor endocytosis. |
2024-09-30 |
2024-10-03 |
Not clear |
Misaki Morishita, Shinji Matsud. SARM1 is essential for NMDA receptor-dependent endocytosis of AMPA receptors in hippocampal neurons. Neuroscience research. 2024-09-30. PMID:39349221. |
in this study, we showed that small interfering rna (sirna)-mediated knockdown of sterile alpha and toll/interleukin receptor motif containing 1 (sarm1) in cultured hippocampal neurons prevented the n-methyl-d-aspartate (nmda)-induced reduction in cell surface ampa receptors. |
2024-09-30 |
2024-10-03 |
Not clear |
Misaki Morishita, Shinji Matsud. SARM1 is essential for NMDA receptor-dependent endocytosis of AMPA receptors in hippocampal neurons. Neuroscience research. 2024-09-30. PMID:39349221. |
these results suggest that both the mitochondrial localization and nadase activity of sarm1 are essential for nmda receptor-dependent ampa receptor internalization in the hippocampal neurons. |
2024-09-30 |
2024-10-03 |
Not clear |
Misaki Morishita, Shinji Matsud. SARM1 is essential for NMDA receptor-dependent endocytosis of AMPA receptors in hippocampal neurons. Neuroscience research. 2024-09-30. PMID:39349221. |
sarm1 is essential for nmda receptor-dependent endocytosis of ampa receptors in hippocampal neurons. |
2024-09-30 |
2024-10-03 |
Not clear |
Misaki Morishita, Shinji Matsud. SARM1 is essential for NMDA receptor-dependent endocytosis of AMPA receptors in hippocampal neurons. Neuroscience research. 2024-09-30. PMID:39349221. |
moreover, the inhibition of the nadase activity of sarm1 blocked the nmda-induced reduction of cell surface ampa receptors. |
2024-09-30 |
2024-10-03 |
Not clear |
Misaki Morishita, Shinji Matsud. SARM1 is essential for NMDA receptor-dependent endocytosis of AMPA receptors in hippocampal neurons. Neuroscience research. 2024-09-30. PMID:39349221. |
overexpression of the sirna-resistant form of sarm1 in sarm1-knocked-down neurons restored ampa receptor trafficking. |
2024-09-30 |
2024-10-03 |
Not clear |