| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aggeliki Tserga, Jean Sébastien Saulnier-Blache, Kostantinos Palamaris, Despoina Pouloudi, Harikleia Gakiopoulou, Jerome Zoidakis, Joost Peter Schanstra, Antonia Vlahou, Manousos Makridaki. Complement Cascade Proteins Correlate with Fibrosis and Inflammation in Early-Stage Type 1 Diabetic Kidney Disease in the Ins2Akita Mouse Model. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338666. |
data were extracted from a previously published quantitative-mass-spectrometry-based proteomics analysis of kidney glomeruli of 2 (early dkd) and 4 months (moderately advanced dkd)-old ins2akita mice and their controls a spearman rho correlation analysis of complement- versus inflammation- and fibrosis-related protein expression was performed. |
2024-02-10 |
2024-02-12 |
mouse |
| Seyoung Yu, Won-Il Choi, Yo Jun Choi, Hye-Youn Kim, Friedhelm Hildebrandt, Heon Yung Ge. PLCE1 regulates the migration, proliferation, and differentiation of podocytes. Experimental & molecular medicine. vol 52. issue 4. 2021-08-02. PMID:32238860. |
plce1 colocalized with rho gtpases in glomeruli. |
2021-08-02 |
2023-08-13 |
Not clear |
| Heon Yung Gee, Fujian Zhang, Shazia Ashraf, Stefan Kohl, Carolin E Sadowski, Virginia Vega-Warner, Weibin Zhou, Svjetlana Lovric, Humphrey Fang, Margaret Nettleton, Jun-yi Zhu, Julia Hoefele, Lutz T Weber, Ludmila Podracka, Andrej Boor, Henry Fehrenbach, Jeffrey W Innis, Joseph Washburn, Shawn Levy, Richard P Lifton, Edgar A Otto, Zhe Han, Friedhelm Hildebrand. KANK deficiency leads to podocyte dysfunction and nephrotic syndrome. The Journal of clinical investigation. vol 125. issue 6. 2015-08-12. PMID:25961457. |
in rat glomeruli and cultured human podocytes, kank2 interacted with arhgdia, a known regulator of rho gtpases in podocytes that is dysfunctional in some types of nephrotic syndrome. |
2015-08-12 |
2023-08-13 |
human |
| Heon Yung Gee, Pawaree Saisawat, Shazia Ashraf, Toby W Hurd, Virginia Vega-Warner, Humphrey Fang, Bodo B Beck, Olivier Gribouval, Weibin Zhou, Katrina A Diaz, Sivakumar Natarajan, Roger C Wiggins, Svjetlana Lovric, Gil Chernin, Dominik S Schoeb, Bugsu Ovunc, Yaacov Frishberg, Neveen A Soliman, Hanan M Fathy, Heike Goebel, Julia Hoefele, Lutz T Weber, Jeffrey W Innis, Christian Faul, Zhe Han, Joseph Washburn, Corinne Antignac, Shawn Levy, Edgar A Otto, Friedhelm Hildebrand. ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling. The Journal of clinical investigation. vol 123. issue 8. 2013-10-22. PMID:23867502. |
we demonstrated that arhgdia is in a complex with rho gtpases and is prominently expressed in podocytes of rat glomeruli. |
2013-10-22 |
2023-08-12 |
human |