All Relations between pla2r1 and insulin

Publication Sentence Publish Date Extraction Date Species
Am\\xc3\\xa9lie Massemin, Delphine Goehrig, Jean-Michel Flaman, Sara Jaber, Audrey Griveau, Sophia Djebali, Elisabeth Marcos, L\\xc3\\xa9a Payen, Jacqueline Marvel, Romain Parent, Serge Adnot, Philippe Bertolino, Jennifer Rieusset, Antonin Tortereau, David Vindrieux, David Bernar. Loss of Pla2r1 decreases cellular senescence and age-related alterations caused by aging and Western diets. Aging cell. 2023-09-05. PMID:37667516. in this study, we investigated the role of the pro-senescent phospholipase a2 receptor 1 (pla2r1) in regulating some age-related alterations in old mice and in mice subjected to a western diet, whereas aged wild-type mice displayed a decreased ability to regulate their glycemia during glucose and insulin tolerance tests, aged pla2r1 knockout (ko) mice efficiently regulated their glycemia and displayed fewer signs of aging. 2023-09-05 2023-09-07 mouse