| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kangfan Ji, Xiangqian Wei, Anna R Kahkoska, Juan Zhang, Yang Zhang, Jianchang Xu, Xinwei Wei, Wei Liu, Yanfang Wang, Yuejun Yao, Xuehui Huang, Shaoqian Mei, Yun Liu, Shiqi Wang, Zhengjie Zhao, Ziyi Lu, Jiahuan You, Guangzheng Xu, Youqing Shen, John B Buse, Jinqiang Wang, Zhen G. An orally administered glucose-responsive polymeric complex for high-efficiency and safe delivery of insulin in mice and pigs. Nature nanotechnology. 2024-09-02. PMID:39223256. |
an orally administered glucose-responsive polymeric complex for high-efficiency and safe delivery of insulin in mice and pigs. |
2024-09-02 |
2024-09-05 |
mouse |
| Edith J Mayorga, Erin A Horst, Brady M Goetz, Sonia Rodriguez-Jimenez, Megan A Abeyta, Mohmmad Al-Qaisi, Robert P Rhoads, Joshua T Selsby, Lance H Baumgar. Therapeutic effects of mitoquinol during an acute heat stress challenge in growing barrows. Journal of animal science. 2024-06-11. PMID:38860702. |
heat-stressed pigs had decreased circulating insulin relative to their tn counterparts (47%; p=0.04); however, the insulin:feed intake ratio tended to increase in hs relative to tn pigs (p=0.09). |
2024-06-11 |
2024-06-14 |
Not clear |
| Ingrid Anna Teigen, Marte Kierulf Åm, Misbah Riaz, Sverre Christian Christiansen, Sven Magnus Carlse. Effects of Low-Dose Glucagon on Subcutaneous Insulin Absorption in Pigs. Current therapeutic research, clinical and experimental. vol 100. 2024-03-21. PMID:38511103. |
effects of low-dose glucagon on subcutaneous insulin absorption in pigs. |
2024-03-21 |
2024-03-23 |
Not clear |
| Lei Liu, Wei Wang, Weiwei Liu, Xingzheng Li, Guoqiang Yi, Adeyinka Abiola Adetula, Haibo Huang, Zhonglin Tan. Comprehensive Atlas of Alternative Splicing Reveals NSRP1 Promoting Adipogenesis through International journal of molecular sciences. vol 25. issue 5. 2024-03-13. PMID:38474122. |
adipose deposition in eastern pigs might be linked to the down-regulation of immune-inflammation-related pathways and reduced insulin resistance. |
2024-03-13 |
2024-03-15 |
Not clear |
| Ditte Olsen Lützhøft, Cecilie Bækgård, Elizabeth Wimborne, Ellen Marie Straarup, Karen-Margrethe Pedersen, Jonathan R Swann, Henrik Duelund Pedersen, Kim Kristensen, Line Morgills, Dennis Sandris Nielsen, Axel Kornerup Hansen, Marianne Kronborg Bracken, Susanna Cirera, Berit Østergaard Christofferse. High fat diet is associated with gut microbiota dysbiosis and decreased gut microbial derived metabolites related to metabolic health in young Göttingen Minipigs. PloS one. vol 19. issue 3. 2024-03-01. PMID:38427692. |
the hfd-fed pigs presented with metabolic syndrome, gut microbial dysbiosis and a marked decrease in healthy gut microbial products and thus displayed marked parallels to human obesity and insulin resistance. |
2024-03-01 |
2024-03-04 |
human |
| Evelyn J Salvaris, Nella Fisicaro, Stephen McIlfatrick, Adwin Thomas, Erin Fuller, Andrew M Lew, Mark B Nottle, Wayne J Hawthorne, Peter J Cowa. Characterisation of transgenic pigs expressing a human T cell-depleting anti-CD2 monoclonal antibody. Xenotransplantation. 2023-11-14. PMID:37961013. |
in this study, we generated ggta1 knock-in pigs in which mhcip was replaced by the β-cell-specific porcine insulin promoter (pip), and compared the pattern of diliximab expression in the two lines. |
2023-11-14 |
2023-11-20 |
human |
| Sathiya Varadarajan, Arumugam Muruganandam, V Ramesh Kuma. Development and Characterization of Guinea Pig Anti-Insulin Polyclonal Antibody. Applied biochemistry and biotechnology. 2023-09-15. PMID:37713062. |
the paper describes the use of insulin as a target antigen and the development of target (insulin) specific antibodies in guinea pigs for use as a positive control for immunogenicity kit validation. |
2023-09-15 |
2023-10-07 |
Not clear |
| Sathiya Varadarajan, Arumugam Muruganandam, V Ramesh Kuma. Development and Characterization of Guinea Pig Anti-Insulin Polyclonal Antibody. Applied biochemistry and biotechnology. 2023-09-15. PMID:37713062. |
anti-insulin polyclonal antibody was raised against insulin in the dunkin hartley guinea pigs host. |
2023-09-15 |
2023-10-07 |
Not clear |
| Mahdi Ghavami, Jesper Pedersen, Rolf Bech Kjeldsen, Aage Kristian Olsen Alstrup, Zhongyang Zhang, Vasiliki Koulianou, Johan Palmfeldt, Thomas Vorup-Jensen, Lasse Højlund Eklund Thamdrup, Anja Boise. A self-unfolding proximity enabling device for oral delivery of macromolecules. Journal of controlled release : official journal of the Controlled Release Society. 2023-07-28. PMID:37506850. |
one device version is a self-unfolding foil that we have used to deliver insulin and nisin to rats and pigs respectively. |
2023-07-28 |
2023-08-14 |
rat |
| Mahdi Ghavami, Jesper Pedersen, Rolf Bech Kjeldsen, Aage Kristian Olsen Alstrup, Zhongyang Zhang, Vasiliki Koulianou, Johan Palmfeldt, Thomas Vorup-Jensen, Lasse Højlund Eklund Thamdrup, Anja Boise. A self-unfolding proximity enabling device for oral delivery of macromolecules. Journal of controlled release : official journal of the Controlled Release Society. 2023-07-28. PMID:37506850. |
in our study, this device has shown a great potential for delivering peptides, with a significant increase in the absorption of solid dosage of insulin by ~12 times and nisin by ~4 times in rats and pigs, respectively. |
2023-07-28 |
2023-08-14 |
rat |
| He Zhang, Xiaoxi Yan, Ailian Lin, Pengke Xia, Yong S. Inhibition of ghrelin activity by the receptor antagonist [D-Lys3]-GHRP-6 enhances hepatic fatty acid oxidation and gluconeogenesis in a growing pig model. Peptides. 2023-06-10. PMID:37301480. |
dlys treatment significantly increased serum nefa and insulin levels, hepatic glucose level and homa-ir, and significantly decreased serum tba level of growing pigs after fasting. |
2023-06-10 |
2023-08-14 |
Not clear |
| Huanqi Peng, Kaiyi Zhang, Jiakun Miao, Yu Yang, Shuang Xu, Tianwen Wu, Cong Tao, Yanfang Wang, Shulin Yan. SnRNA-Seq of Pancreas Revealed the Dysfunction of Endocrine and Exocrine Cells in Transgenic Pigs with Prediabetes. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175407. |
compared to wild-type (wt) pigs, piginh11 pigs showed similar pathological manifestations to type 2 diabetes patients, such as insulin deficiency, fatty deposition, inflammatory infiltration, fibrosis tissue necrosis, double positive cells, endoplasmic reticulum (er) and mitochondria damage. |
2023-05-14 |
2023-08-14 |
human |
| Minji Kim, Ji-Eun Park, Yongjin Lee, Seung-Tae Lee, Geun-Shik Lee, Sang-Hwan Hyun, Eunsong Lee, Joohyeong Le. Effect of Growth Factors and Hormones during In Vitro Growth Culture of Cumulus-Oocyte-Complexes Derived from Small Antral Follicles in Pigs. Animals : an open access journal from MDPI. vol 13. issue 7. 2023-04-13. PMID:37048462. |
in conclusion, this study demonstrates that insulin treatment during ivg culture improves the maturational and developmental competence of oocytes derived from safs in pigs through its effect on cumulus cell expansion and cytoplasmic microenvironments, such as gsh, ros, and mpf activity. |
2023-04-13 |
2023-08-14 |
Not clear |
| Theo A T G van Kempen, Ruurd T Zijlstr. Eat like a Pig to Combat Obesity. Metabolites. vol 13. issue 3. 2023-03-29. PMID:36984860. |
epigenetic programing predisposes pigs to insulin insensitivity, but pigs seem to sense this insensitivity and consequently eat less, preventing obesity. |
2023-03-29 |
2023-08-14 |
human |
| Audrey I S Andersen-Civil, Stig M Thamsborg, Andrew R William. Profiling of hepatic transcriptomes reveals modulatory effects of parasitic infection on the metabolic response to dietary polyphenols in pigs. The Journal of nutritional biochemistry. 2023-03-20. PMID:36940885. |
in uninfected pigs, pac supplementation markedly changed the liver transcriptome including genes related to carbohydrate and lipid metabolism, insulin signaling, and bile acid synthesis. |
2023-03-20 |
2023-08-14 |
Not clear |
| Ana Heras-Molina, Natalia Yeste, José Luis Pesantez-Pacheco, Susana Astiz, Marta Vazquez-Gomez, Arianna Bettiga, Francesco Trevisani, Consolacion Garcia-Contreras, Sergio Luis-Lima, Anna Bassols, Esteban Porrini, Antonio Gonzalez-Bulne. Obesity and Metabolic Traits after High-Fat Diet in Iberian Pigs with Low Birth Weight of Placental Origin. Biology. vol 11. issue 10. 2023-03-08. PMID:36290436. |
there were no differences in metabolic traits during juvenile development, but there were differences in adulthood, when lbw pigs showed higher glucose and lower insulin levels than nbw pigs (both p < 0.05). |
2023-03-08 |
2023-08-16 |
Not clear |
| Fuminori Tanihara, Maki Hirata, Zhao Namula, Lanh Thi Kim Do, Naoaki Yoshimura, Qingyi Lin, Koki Takebayashi, Tetsushi Sakuma, Takashi Yamamoto, Takeshige Oto. Pigs with an Frontiers in cell and developmental biology. vol 11. 2023-01-30. PMID:36711037. |
pigs with an just one amino acid at the carboxy-terminus of the b chain distinguishes human insulin from porcine insulin. |
2023-01-30 |
2023-08-14 |
human |
| F A Eugenio, J van Milgen, J Duperray, R Sergheraert, N Le Floc'. Feeding pigs amino acids as protein-bound or in free form influences postprandial concentrations of amino acids, metabolites, and insulin. Animal : an international journal of animal bioscience. vol 17. issue 1. 2022-12-21. PMID:36542911. |
feeding pigs amino acids as protein-bound or in free form influences postprandial concentrations of amino acids, metabolites, and insulin. |
2022-12-21 |
2023-08-14 |
Not clear |
| Marllon José Karpeggiane de Oliveira, Antonio Diego Brandão Melo, Danilo Alves Marçal, Graziela Alves da Cunha Valini, Cleslei Alisson Silva, Alini Mari Veira, Alícia Zem Fraga, Pedro Righetti Arnaut, Paulo Henrique Reis Furtado Campos, Luan Sousa Dos Santos, John Khun Kyaw Htoo, Henrique Gastmann Brand, Luciano Hauschil. Effects of lowering dietary protein content without or with increased protein-bound and feed-grade amino acids supply on growth performance, body composition, metabolism, and acute-phase protein of finishing pigs under daily cyclic heat stress. Journal of animal science. 2022-11-24. PMID:36420675. |
lpaa+ pigs had lower (p < 0.05) insulin than lpaa. |
2022-11-24 |
2023-08-14 |
Not clear |
| Hector Hernando Salgado, Candido Pomar, Marie-France Palin, Hélène Lapierre, Marie-Pierre Létourneau-Montminy, John P Cant, Aline Remu. Insulin sensitivity is associated with the observed variation of de novo lipid synthesis and body composition in finishing pigs. Scientific reports. vol 12. issue 1. 2022-08-26. PMID:36028540. |
insulin sensitivity is associated with the observed variation of de novo lipid synthesis and body composition in finishing pigs. |
2022-08-26 |
2023-08-14 |
Not clear |