| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Phillip R Kramer, Rebecca S Hornung, Mikhail Umorin, M Douglas Benson, Paul R Kinchingto. Neurexin 3 Regulates Synaptic Connections Between Central Amygdala Neurons and Excitable Cells of the Lateral Parabrachial Nucleus in Rats with Varicella Zoster Induced Orofacial Pain. Journal of pain research. vol 17. 2024-07-08. PMID:38974829. |
attenuating nrxn3 expression in the central amygdala increased gaba release in the lateral parabrachial nucleus suggesting nrxn3 controls pain by regulating gaba release. |
2024-07-08 |
2024-07-11 |
rat |
| Phillip R Kramer, Mikhail Umorin, Rebecca Hornung, M Douglas Benson, Paul R Kinchingto. Sex Differences in the Role of Neurexin 3α in Zoster Associated Pain. Frontiers in integrative neuroscience. vol 16. 2022-07-25. PMID:35875508. |
these results are consistent with the idea that nrxn3 within the central amygdala controls vzv associated pain by regulating gaba release in the lateral parabrachial that then modulates ascending orofacial pain signals. |
2022-07-25 |
2023-08-14 |
rat |
| Phillip R Kramer, Mikhail Umorin, Rebecca Hornung, Paul R Kinchingto. Neurexin 3α in the central amygdala has a role orofacial varicella zoster pain. Neuroscience. 2022-06-09. PMID:35679996. |
results revealed that attenuating nrxn3 expression within the amygdala reduces gaba release in the parabrachial and increases neuronal activity within the lateral parabrachial region. |
2022-06-09 |
2023-08-14 |
human |
| Phillip R Kramer, Mikhail Umorin, Rebecca Hornung, Paul R Kinchingto. Neurexin 3α in the central amygdala has a role orofacial varicella zoster pain. Neuroscience. 2022-06-09. PMID:35679996. |
these results are consistent with the idea that nrxn3 within the central amygdala controls vzv associated pain by regulating gaba release in the lateral parabrachial that then controls the activity of ascending pain neurons. |
2022-06-09 |
2023-08-14 |
human |
| Phillip R Kramer, Mikhail Umorin, Rebecca Hornung, Paul R Kinchingto. Neurexin 3α in the central amygdala has a role orofacial varicella zoster pain. Neuroscience. 2022-06-09. PMID:35679996. |
to test the hypothesis nrxn3 expression was knocked down (i.e., using shrna) in the central amygdala and gaba release and neuronal activity were quantitated in the parabrachial concomitant with measurement of the vzv induced pain response. |
2022-06-09 |
2023-08-14 |
human |
| Phillip R Kramer, Mikhail Umorin, Rebecca Hornung, Paul R Kinchingto. Neurexin 3α in the central amygdala has a role orofacial varicella zoster pain. Neuroscience. 2022-06-09. PMID:35679996. |
activating gabaergic neurons within the central amygdala with opsins increase gaba release in the parabrachial and reduced the pain response after nrxn3 shrna treatment. |
2022-06-09 |
2023-08-14 |
human |