| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ida Kupcova, Lubos Danisovic, Sona Bernatova, Stefan Harsany. Analysis of Salivary Neuropeptides in Anxiety and Depression Using the Luminex MAGPIX® System. Cureus. vol 16. issue 8. 2024-09-30. PMID:39347144. |
anxiety and depressive disorders are highly prevalent mental health conditions, affecting millions worldwide. advancements in neurobiology have identified the effects of various neuropeptides in modulating mood and stress responses. some of the well-researched neuropeptides in plasma are oxytocin (oxt), alpha-melanocyte-stimulating hormone (alpha-msh), beta-endorphin, neurotensin, and substance p. in this study, we used methods of liquid biopsy to acquire saliva samples to analyze the concentrations of neuropeptides associated with depression. |
2024-09-30 |
2024-10-02 |
Not clear |
| Rebecca Ryznar, Nathan Andrews, Kyle Emery, Michaela Snow, Mark Payton, Francina Towne, Dean Guble. Specific Salivary Neuropeptides Shift Synchronously during Acute Stress in Fire Recruits. Brain sciences. vol 14. issue 5. 2024-05-25. PMID:38790470. |
salivary samples were collected from fire recruits engaged in a stress training exercise previously shown to induce acute stress, at three separate timepoints during the exercise and levels of oxytocin, neurotensin, substance p, α-msh, and β-endorphin were measured using the human neuropeptide 5-plex custom assay eve technologies. |
2024-05-25 |
2024-05-27 |
human |
| Wenxi Sun, Tingting Jin, Haidong Yang, Jin Li, Qing Tian, Ju Gao, Ruijie Peng, Guangya Zhang, Xiaobin Zhan. Alterations of serum neuropeptide levels and their relationship to cognitive impairment and psychopathology in male patients with chronic schizophrenia. Schizophrenia (Heidelberg, Germany). vol 10. issue 1. 2024-01-03. PMID:38172494. |
after the above participants were enrolled, we examined the repeatable battery for the assessment of neuropsychological status (rbans) and the blood serum levels of α-melanocyte stimulating hormone (α-msh), β-endorphin (be), neurotensin (nt), oxytocin (ot) and substance.p (s.p). |
2024-01-03 |
2024-01-06 |
human |
| Daniel B Andersen, Jens J Hols. Peptides in the regulation of glucagon secretion. Peptides. vol 148. 2021-12-02. PMID:34748791. |
hormones that may regulate glucagon secretion include locally produced insulin and somatostatin, but also urocortin-3, amylin and pancreatic polypeptide, and from outside the pancreas glucagon-like peptide-1 and 2, peptide tyrosine tyrosine and oxyntomodulin, glucose-dependent insulinotropic polypeptide, neurotensin and ghrelin, as well as the hypothalamic hormones arginine-vasopressin and oxytocin, and calcitonin from the thyroid. |
2021-12-02 |
2023-08-13 |
Not clear |
| L Kobylinska, M A Ghita, C Caruntu, G Gabreanu, C P Tataru, S V Badescu, O Geicu, M Neagu, C Constantin, I Dobrescu, L Zagrea. PRELIMINARY INSIGHTS IN OXYTOCIN ASSOCIATION WITH THE ONSET OF DIABETIC NEUROPATHY. Acta endocrinologica (Bucharest, Romania : 2005). vol 13. issue 2. 2020-10-01. PMID:31149183. |
this pilot study presents a series of 3 patients with type 1 diabetes and diabetic neuropathy in which the values of plasma oxytocin, neurotensin, β-endorphins, α-msh, substance p and orexin a were measured in comparison to 3 healthy controls with matching ages. |
2020-10-01 |
2023-08-13 |
Not clear |
| L Kobylinska, M A Ghita, C Caruntu, G Gabreanu, C P Tataru, S V Badescu, O Geicu, M Neagu, C Constantin, I Dobrescu, L Zagrea. PRELIMINARY INSIGHTS IN OXYTOCIN ASSOCIATION WITH THE ONSET OF DIABETIC NEUROPATHY. Acta endocrinologica (Bucharest, Romania : 2005). vol 13. issue 2. 2020-10-01. PMID:31149183. |
in the diabetic patients group, there was a strong negative correlation between the value of plasma glucose and oxytocin (r=-0.99, p=0.04), respectively neurotensin (r=-0.99, p=0.03). |
2020-10-01 |
2023-08-13 |
Not clear |
| L Kobylinska, M A Ghita, C Caruntu, G Gabreanu, C P Tataru, S V Badescu, O Geicu, M Neagu, C Constantin, I Dobrescu, L Zagrea. PRELIMINARY INSIGHTS IN OXYTOCIN ASSOCIATION WITH THE ONSET OF DIABETIC NEUROPATHY. Acta endocrinologica (Bucharest, Romania : 2005). vol 13. issue 2. 2020-10-01. PMID:31149183. |
the results suggest that oxytocin, in conjunction with neurotensin, could be investigated as a potential early detection marker of diabetic neuropathy and, to our knowledge, this is the first report focusing on plasma oxytocin levels in patients with diabetic neuropathy. |
2020-10-01 |
2023-08-13 |
Not clear |
| Dasiel O Borroto-Escuela, Jens Carlsson, Patricia Ambrogini, Manuel Narváez, Karolina Wydra, Alexander O Tarakanov, Xiang Li, Carmelo Millón, Luca Ferraro, Riccardo Cuppini, Sergio Tanganelli, Fang Liu, Malgorzata Filip, Zaida Diaz-Cabiale, Kjell Fux. Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:28270751. |
neuromodulation of neuronal networks in schizophrenia via da, adenosine, glutamate, 5-ht and neurotensin peptides and oxytocin, involving a2ar-d2r, d2r-nmdar, a2ar-d2r-mglur5, d2r-5-ht2a and d2r-oxytocinr heteroreceptor complexes opens up a new world of d2r protomer targets in the listed heterocomplexes for treatment of positive, negative and cognitive symptoms of schizophrenia. |
2020-09-30 |
2023-08-13 |
Not clear |
| Thiago B Kirsten, Renato C Casarin, Maria M Bernardi, Luciano F Felici. Pioglitazone abolishes cognition impairments as well as BDNF and neurotensin disturbances in a rat model of autism. Biology open. vol 8. issue 5. 2020-02-25. PMID:31036753. |
t-maze spontaneous alternations tests, plasma levels of brain-derived neurotrophic factor (bdnf), beta-endorphin, neurotensin, oxytocin, and substance p were all studied. |
2020-02-25 |
2023-08-13 |
rat |
| Kesava Kovanur-Sampath, Ramakrishnan Mani, Jim Cotter, Angela Spontelli Gisselman, Steve Tumilt. Changes in biochemical markers following spinal manipulation-a systematic review and meta-analysis. Musculoskeletal science & practice. vol 29. 2018-10-23. PMID:28399479. |
there was also a low quality evidence that spinal manipulation is better than control at post-intervention in increasing substance-p (smd -0.48,95%ci-0.87 to -0.1), neurotensin (smd -1.8,95%ci-2.56 to -1.04) and oxytocin levels (smd -2.61,95%ci-3.5to-1.72). |
2018-10-23 |
2023-08-13 |
human |
| Kesava Kovanur-Sampath, Ramakrishnan Mani, Jim Cotter, Angela Spontelli Gisselman, Steve Tumilt. Changes in biochemical markers following spinal manipulation-a systematic review and meta-analysis. Musculoskeletal science & practice. vol 29. 2018-10-23. PMID:28399479. |
the current review found that spinal manipulation can increase substance-p, neurotensin, oxytocin and interleukin levels and may influence cortisol levels post-intervention. |
2018-10-23 |
2023-08-13 |
human |
| Shyam L Gupta, Vikas Dhiman, T Jayasekharan, N K Saho. Analysis of argentinated peptide complexes using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: Peptide = oxytocin, arg(8) -vasopressin, bradykinin, bombesin, somatostatin, neurotensin. Rapid communications in mass spectrometry : RCM. vol 30. issue 11. 2017-09-13. PMID:27173113. |
analysis of argentinated peptide complexes using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: peptide = oxytocin, arg(8) -vasopressin, bradykinin, bombesin, somatostatin, neurotensin. |
2017-09-13 |
2023-08-13 |
Not clear |
| Masaaki Yoshikaw. Bioactive peptides derived from natural proteins with respect to diversity of their receptors and physiological effects. Peptides. vol 72. 2016-08-22. PMID:26297549. |
we have found various bioactive peptides derived from animal and plant proteins, which interact with receptors for endogenous bioactive peptides such as opioids, neurotensin, complements c3a and c5a, oxytocin, and formyl peptides etc. |
2016-08-22 |
2023-08-13 |
Not clear |
| Ulrich Herget, Soojin Ry. Coexpression analysis of nine neuropeptides in the neurosecretory preoptic area of larval zebrafish. Frontiers in neuroanatomy. vol 9. 2015-03-02. PMID:25729355. |
to identify distinct cell types present in the larval npo, we also generated a comprehensive 3d map of 9 zebrafish homologs of typical neuropeptides found in the mammalian pvn (arginine vasopressin (avp), corticotropin-releasing hormone (crh), proenkephalin a (penka)/b (penkb), neurotensin (nts), oxytocin (oxt), vasoactive intestinal peptide (vip), cholecystokinin (cck), and somatostatin (sst)). |
2015-03-02 |
2023-08-13 |
human |
| Débora N Okamoto, Marcia Y Kondo, Lilian C G Oliveira, Rodrigo V Honorato, Leticia M Zanphorlin, Monika A Coronado, Mariana S Araújo, Guacyara da Motta, Camila L Veronez, Sheila S Andrade, Paulo S L Oliveira, Raghuvir K Arni, Adelia C O Cintra, Suely V Sampaio, Maria A Juliano, Luiz Juliano, Mário T Murakami, Iuri E Gouve. P-I class metalloproteinase from Bothrops moojeni venom is a post-proline cleaving peptidase with kininogenase activity: insights into substrate selectivity and kinetic behavior. Biochimica et biophysica acta. vol 1844. issue 3. 2014-05-09. PMID:24373874. |
bmoompα-i, a p-i class smvp from bothrops moojeni venom, was active upon neuro- and vaso-active peptides including angiotensin i, bradykinin, neurotensin, oxytocin and substance p. interestingly, bmoompα-i showed a strong bias towards hydrolysis after proline residues, which is unusual for most of characterized peptidases. |
2014-05-09 |
2023-08-12 |
Not clear |
| Amber L LaCrosse, M Foster Oliv. Neuropeptide systems and schizophrenia. CNS & neurological disorders drug targets. vol 12. issue 5. 2014-03-03. PMID:23574175. |
such neuropeptide systems include neurotensin, cholecystokinin, corticotropin releasing factor, neuropeptide y, oxytocin, opioid peptides, tachykinins, thyrotropin-releasing hormone, and orexins. |
2014-03-03 |
2023-08-12 |
Not clear |
| M S Star. Influence of peptides on (3)H-dopamine release from superfused rat striatal slices. Neurochemistry international. vol 4. issue 4. 2012-10-02. PMID:20487873. |
substance p (sp), neurotensin and somatostatin all actively released (3)h-da, whilst cholecystokinin octapeptide (cck), luteinising hormone releasing hormone (lhrh), thyrotrophin releasing hormone (trh), adrenocorticotrophin (acth), vasopressin and oxytocin were without effect on spontaneous (3)h-da efflux. |
2012-10-02 |
2023-08-12 |
rat |
| M S Star. Influence of peptides on (3)H-dopamine release from superfused rat striatal slices. Neurochemistry international. vol 4. issue 4. 2012-10-02. PMID:20487873. |
the effects of the peptides on k(+)-induced (3)h-da overflow were more varied; neurotensin, trh and acth had no effect, whereas cck, somatostatin and lhrh potentiated and sp, vasopressin and oxytocin attenuated (3)h-da release. |
2012-10-02 |
2023-08-12 |
rat |
| Paul McGonigl. Peptide therapeutics for CNS indications. Biochemical pharmacology. vol 83. issue 5. 2012-03-15. PMID:22051078. |
both clinical and preclinical data has been accumulated supporting the potential utility of agonists at central neurotensin, cholecystokinin, neuropeptide y and oxytocin receptors. |
2012-03-15 |
2023-08-12 |
Not clear |
| K S Foo, H Brismar, C Broberge. Distribution and neuropeptide coexistence of nucleobindin-2 mRNA/nesfatin-like immunoreactivity in the rat CNS. Neuroscience. vol 156. issue 3. 2009-04-14. PMID:18761059. |
double-labeling immunohistochemistry revealed colocalization of nesfatin with vasopressin and oxytocin in magnocellular neuroendocrine neurons, thyrotropin-releasing hormone, corticotropin-releasing hormone, somatostatin, neurotensin, and growth-hormone-releasing hormone in parvocellular neuroendocrine neurons, pro-opiomelanocortin (but not neuropeptide y) in the arcuate nucleus and melanin-concentrating hormone (but not hypocretin) in the lateral hypothalamus. |
2009-04-14 |
2023-08-12 |
rat |