| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Linhe Lu, Yalan Shao, Nisha Wang, Xiang Xiong, Mengen Zhai, Jiayou Tang, Yang Liu, Jian Yang, Lifang Yan. Follistatin-like protein 1 attenuates doxorubicin-induced cardiomyopathy by inhibiting MsrB2-mediated mitophagy. Molecular and cellular biochemistry. 2024-05-02. PMID:38696001. |
fstl1 treatment attenuated dox-induced cardiac dysfunction, cardiac fibrosis, and cellular apoptosis by inhibiting excess mitochondrial matrix protein methionine sulfoxide reductase b2 (msrb2)-mediated mitophagy. |
2024-05-02 |
2024-05-04 |
Not clear |
| Seung Hee Lee, Suho Lee, Jing Du, Kanika Jain, Min Ding, Anis J Kadado, Gourg Atteya, Zainab Jaji, Tarun Tyagi, Won-Ho Kim, Raimund I Herzog, Amar Patel, Costin N Ionescu, Kathleen A Martin, John Hw. Mitochondrial MsrB2 serves as a switch and transducer for mitophagy. EMBO molecular medicine. vol 11. issue 8. 2020-05-04. PMID:31282614. |
this biochemical signaling only occurs at damaged mitochondria where msrb2 is released from the mitochondrial matrix. |
2020-05-04 |
2023-08-13 |
human |
| Seung Hee Lee, Suho Lee, Jing Du, Kanika Jain, Min Ding, Anis J Kadado, Gourg Atteya, Zainab Jaji, Tarun Tyagi, Won-Ho Kim, Raimund I Herzog, Amar Patel, Costin N Ionescu, Kathleen A Martin, John Hw. Mitochondrial MsrB2 serves as a switch and transducer for mitophagy. EMBO molecular medicine. vol 11. issue 8. 2020-05-04. PMID:31282614. |
we now report that the mitochondrial matrix protein msrb2 plays an important role in switching on mitophagy by reducing parkin methionine oxidation (meto), and transducing mitophagy through ubiquitination by parkin and interacting with lc3. |
2020-05-04 |
2023-08-13 |
human |