| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiayue Su, Xuyang Tian, Hang Cheng, Desheng Liu, Ziyi Wang, Shan Sun, Hong-Wei Wang, Sen-Fang Su. Structural insight into synergistic activation of human 3-methylcrotonyl-CoA carboxylase. Nature structural & molecular biology. 2024-09-02. PMID:39223421. |
the enzymes 3-methylcrotonyl-coenzyme a (coa) carboxylase (mcc), pyruvate carboxylase and propionyl-coa carboxylase belong to the biotin-dependent carboxylase family located in mitochondria. |
2024-09-02 |
2024-09-05 |
human |
| Rodrigue Yossa, Pallab K Sarker, Santhosh Karanth, Marc Ekker, Grant W Vandenber. Effects of dietary biotin and avidin on growth, survival, feed conversion, biotin status and gene expression of zebrafish Danio rerio. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 160. issue 4. 2012-02-03. PMID:21839851. |
elevated levels of acetyl coa carboxylase-a (acca), methylcrotonyl coa carboxylase (mcc) and propionyl coa carboxylase-a (pcca) transcripts were recorded in fish fed the control diet, in comparison to the other diets. |
2012-02-03 |
2023-08-12 |
zebrafish |
| Donald M Mock, Shawna L Stratton, Thomas D Horvath, Anna Bogusiewicz, Nell I Matthews, Cindy L Henrich, Amanda M Dawson, Horace J Spencer, Suzanne N Owen, Gunnar Boysen, Jeffery H Mora. Urinary excretion of 3-hydroxyisovaleric acid and 3-hydroxyisovaleryl carnitine increases in response to a leucine challenge in marginally biotin-deficient humans. The Journal of nutrition. vol 141. issue 11. 2011-12-12. PMID:21918059. |
conversion of 3-methylcrotonyl coa to 3-methylglutaconyl coa in the leucine catabolic pathway is catalyzed by the biotin-dependent enzyme methylcrotonyl-coa carboxylase (mcc). |
2011-12-12 |
2023-08-12 |
Not clear |
| G L Feldman, Y E Hsia, B Wol. Biochemical characterization of biotin-responsive multiple carboxylase deficiency: heterogeneity within the bio genetic complementation group. American journal of human genetics. vol 33. issue 5. 1981-12-15. PMID:6794361. |
three biotin-dependent enzymes, pyruvate carboxylase (pc), propionyl coa carboxylase (pcc), and beta-methylcrotonyl coa carboxylase (beta mcc), were biochemically characterized in fibroblasts from two patients with neonatal multiple carboxylase deficiency. |
1981-12-15 |
2023-08-12 |
Not clear |
| B Wolf, F Kalousek, L E Rosenber. Essential arginine residues in the active sites of propionyl CoA carboxylase and beta-methylcrotonyl CoA carboxylase. Enzyme. vol 24. issue 5. 1980-02-15. PMID:510274. |
beta mcc which was similarly inhibited by phenylglyoxal was protected by beta-methylcrotonyl coa and atp. |
1980-02-15 |
2023-08-11 |
human |
| B Wolf, F Kalousek, L E Rosenber. Essential arginine residues in the active sites of propionyl CoA carboxylase and beta-methylcrotonyl CoA carboxylase. Enzyme. vol 24. issue 5. 1980-02-15. PMID:510274. |
at least one arginine residue is essential for substrate binding in or near the active sites of propionyl coa carboxylase (pcc) and beta-methylcrotonyl coa carboxylase (beta mcc) in cultured human fibroblasts. |
1980-02-15 |
2023-08-11 |
human |