| Fatemeh Yazarlou, Mobina Tabibian, Asaad Azarnezhad, Habib Sadeghi Rad, Leonard Lipovich, Golshid Sanati, Hamid Mostafavi Abdolmaleky, Fatemeh Alizade. Evaluating Gene Expression and Methylation Profiles of TCF4, MBP, and EGR1 in Peripheral Blood of Drug-Free Patients with Schizophrenia: Correlations with Psychopathology, Intelligence, and Cognitive Impairment. Journal of molecular neuroscience : MN. 2023-09-05. PMID:37668894.
||evaluating gene expression and methylation profiles of tcf4, mbp, and egr1 in peripheral blood of drug-free patients with schizophrenia: correlations with psychopathology, intelligence, and cognitive impairment.
| M Ayalew, H Le-Niculescu, D F Levey, N Jain, B Changala, S D Patel, E Winiger, A Breier, A Shekhar, R Amdur, D Koller, J I Nurnberger, A Corvin, M Geyer, M T Tsuang, D Salomon, N J Schork, A H Fanous, M C O'Donovan, A B Niculesc. Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction. Molecular psychiatry. vol 17. issue 9. 2013-01-23. PMID:22584867.
||using this polyevidence scoring and pathway analyses, we identify top genes (disc1, tcf4, mbp, mobp, ncam1, nrcam, ndufv2, rab18, as well as adcyap1, bdnf, cnr1, comt, drd2, dtnbp1, gad1, gria1, grin2b, htr2a, nrg1, reln, snap-25, tnik), brain development, myelination, cell adhesion, glutamate receptor signaling, g-protein-coupled receptor signaling and camp-mediated signaling as key to pathophysiology and as targets for therapeutic intervention.