All Relations between lhb and nucleus habenularis lateralis

Publication Sentence Publish Date Extraction Date Species
Anna Zhukovskaya, Zimmerman Christopher, Lindsay Willmore, Alejandro Pan Vazquez, Sanjeev Janarthanan, Annegret Falkner, Ilana Witte. Heightened lateral habenula activity during stress produces brainwide and behavioral substrates of susceptibility. bioRxiv : the preprint server for biology. 2024-07-15. PMID:39005438. here, we seek to determine if activity in the lateral habenula (lhb), which encodes a negative teaching signal, differs between susceptible and resilient mice during stress to produce different outcomes. 2024-07-15 2024-07-18 mouse
Yuanyuan Tian, Junqiang Zheng, Xiao Zhu, Xue Liu, Haoyang Li, Jun Wang, Qian Yang, Ling-Hui Zeng, Zhiguo Shi, Mengyuan Gong, Yuzheng Hu, Han X. A prefrontal-habenular circuitry regulates social fear behaviour. Brain : a journal of neurology. 2024-07-04. PMID:38963812. employing a social fear conditioning paradigm, we induced robust social fear in mice and found that the lateral habenula (lhb) neurons and lhb-projecting mpfc neurons are synchronously activated during social fear expression. 2024-07-04 2024-07-11 mouse
Xue-Zhong Cao, Meng-Ye Zhu, Gang Xu, Fan Li, Yi Yan, Jin-Jin Zhang, Jianbing Wang, Fei Zeng, Yang Bao, Xue-Xue Zhang, Tao Liu, Da-Ying Zhan. HCN channels in the lateral habenula regulate pain and comorbid depressive-like behaviors in mice. CNS neuroscience & therapeutics. vol 30. issue 7. 2024-07-03. PMID:38961317. comorbid anxiodepressive-like symptoms (cads) in chronic pain are closely related to the overactivation of the lateral habenula (lhb). 2024-07-03 2024-07-08 mouse
Hiroyuki Ichijo, Nguyen Thi Van Trang, Tomoya Nakamur. Topographic Organization of Glutamatergic and GABAergic Parvalbumin Positive Neurons in the Lateral Habenula. eNeuro. 2024-07-03. PMID:38960707. parvalbumin-expressing (pv) neurons, classified by their expression of the calcium-binding protein parvalbumin, play crucial roles in the function and plasticity of the lateral habenular nucleus (lhb). 2024-07-03 2024-07-10 mouse
Nur Abdel-Hay, Marina Kabirova, Rami Yak. A discrete subpopulation of PFC-LHb neurons govern cocaine place preference. Translational psychiatry. vol 14. issue 1. 2024-07-02. PMID:38956048. the pfc also projects to the lateral habenula (lhb), a brain region critical for encoding negative reward and regulating the reward system. 2024-07-02 2024-07-06 Not clear
Yingqing Wu, Jia Deng, Jinsong Ma, Yujie Chen, Ning Hu, Shilei Hao, Bochu Wan. Unraveling the Pathogenesis of Post-Stroke Depression in a Hemorrhagic Mouse Model through Frontal Lobe Circuitry and JAK-STAT Signaling. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024-07-01. PMID:38946585. it is demonstrated that depression is a specific neurological complication in the unilateral hematoma model of the mpfc, and the ventral tegmental area (vta) shows a higher percentage of connectivity disruption compared to the lateral habenula (lhb) and striatum (str). 2024-07-01 2024-07-03 mouse
William J Flerlage, Sarah C Simmons, Emily H Thomas, Shawn Gouty, Mumeko C Tsuda, T John Wu, Regina C Armstrong, Brian M Cox, Fereshteh Nugen. Effects of Repetitive Mild Traumatic Brain Injury on Corticotropin-Releasing Factor Modulation of Lateral Habenula Excitability and Motivated Behavior. Journal of neurotrauma. 2024-06-29. PMID:38943284. recent evidence from our laboratory suggests a possible dysregulation within reward/motivational circuit function at the level of a subcortical structure, the lateral habenula (lhb), where we demonstrated a causal role for hyperactive lhb in mtbi-induced motivational deficits in self-care grooming behavior in young adult male mice when exposed to mtbi injury during late adolescence (at ~8 weeks old). 2024-06-29 2024-07-02 mouse
Zehui Zhang, Wei Zhang, Yuanyuan Fang, Na Wang, Guoying Liu, Nan Zou, Zhenbo Song, Hanshu Liu, Longshuo Wang, Qin Xiao, Juanjuan Zhao, Yaling Wang, Ting Lei, Cai Zhang, Xiaofeng Liu, Beilin Zhang, Fenlan Luo, Jianxia Xia, Chao He, Zhian Hu, Shuancheng Ren, Hua Zha. A potentiation of REM sleep-active neurons in the lateral habenula may be responsible for the sleep disturbance in depression. Current biology : CB. 2024-06-29. PMID:38944036. psychiatric disorders with dysfunction of the lateral habenula (lhb) show sleep disturbance, especially a disinhibition of rapid eye movement (rem) sleep in major depression. 2024-06-29 2024-07-02 mouse
Hailan Liu, Na Qu, Natalia Valdez Gonzalez, Marco A Palma, Huamin Chen, Jiani Xiong, Abhinav Choubey, Yongxiang Li, Xin Li, Meng Yu, Hesong Liu, Longlong Tu, Nan Zhang, Na Yin, Kristine Marie Conde, Mengjie Wang, Jonathan Carter Bean, Junying Han, Nikolas Anthony Scarcelli, Yongjie Yang, Kenji Saito, Huxing Cui, Qingchun Tong, Zheng Sun, Chunmei Wang, Xing Cai, Li Lu, Yang He, Yong X. A light-responsive neural circuit suppresses feeding. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-06-19. PMID:38897723. we further show that lateral habenula (lhb) neurons in mice respond to light exposure, which in turn activates 5-ht neurons in the dorsal raphe nucleus (drn). 2024-06-19 2024-06-22 mouse
Xianwei Liu, Han Li, Ruijia Ma, Xiaohan Tong, Jijin Wu, Xiaodan Huang, Kwok-Fai So, Qian Tao, Lu Huang, Song Lin, Chaoran Re. Burst firing in Output-Defined Parallel Habenula Circuit Underlies the Antidepressant Effects of Bright Light Treatment. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024-06-12. PMID:38863324. research highlights the significance of increased bursting in lateral habenula (lhb) neurons in depression and as a focal point for bright light treatment (blt). 2024-06-12 2024-06-14 Not clear
Kaihua Ma, Huaguang Gu, Yanbing Ji. The neuronal and synaptic dynamics underlying post-inhibitory rebound burst related to major depressive disorder in the lateral habenula neuron model. Cognitive neurodynamics. vol 18. issue 3. 2024-06-03. PMID:38826643. a burst behavior observed in the lateral habenula (lhb) neuron related to major depressive disorder has attracted much attention. 2024-06-03 2024-06-05 Not clear
Hoyong Park, Hakyun Ryu, Seungjae Zhang, Jeehae Rhee, ChiHye Chun. Mu-opioid receptor activation in the habenula modulates synaptic transmission and depression-like behaviors. Neurobiology of disease. 2024-05-31. PMID:38821376. first, we found that mor activation decreased both excitatory and inhibitory synaptic transmission onto the lateral habenula (lhb). 2024-05-31 2024-06-02 rat
William J Flerlage, Sarah C Simmons, Emily H Thomas, Shawn Gouty, Mumeko C Tsuda, T John Wu, Regina C Armstrong, Brian M Cox, Fereshteh S Nugen. Effects of Repetitive Mild Traumatic Brain Injury on Corticotropin-Releasing Factor Modulation of Lateral Habenula Excitability and Motivated Behavior. bioRxiv : the preprint server for biology. 2024-05-27. PMID:38798343. recent evidence from our laboratory suggests a possible dysregulation within reward/motivational circuit function at the level of a subcortical structure, the lateral habenula (lhb), where we demonstrated a causal role for hyperactive lhb in mtbi-induced motivational deficits in self-care grooming behavior in young adult male mice when exposed to mtbi injury during late adolescence (at ∼8 weeks old). 2024-05-27 2024-05-31 mouse
Guoyi Tang, Yuan Guo, Ruotong Li, Yixuan Wang, Jie Yang, Shasha Gao, Jian Li. Lateral habenula 5-HT Neurochemistry international. 2024-05-16. PMID:38750961. lateral habenula 5-ht although the output of the lateral habenula (lhb) controls the activity of midbrain dopaminergic and serotonergic systems, which are implicated in the pathophysiology of anxiety, it is not clear the role of lhb 5-ht 2024-05-16 2024-05-27 Not clear
William J Flerlage, Sarah C Simmons, Emily H Thomas, Shawn Gouty, Brian M Cox, Fereshteh S Nugen. Dysregulation of Kappa Opioid Receptor Neuromodulation of Lateral Habenula Synaptic Function following a Repetitive Mild Traumatic Brain Injury. bioRxiv : the preprint server for biology. 2024-05-15. PMID:38746139. substantial evidence suggests a critical role for the lateral habenula (lhb) in pathophysiology of psychiatric disorders. 2024-05-15 2024-05-27 mouse
Jun Wang, Qian Yang, Xue Liu, Jie Li, Ya-Lan Wen, Yuzheng Hu, Tian-Le Xu, Shumin Duan, Han X. The basal forebrain to lateral habenula circuitry mediates social behavioral maladaptation. Nature communications. vol 15. issue 1. 2024-05-13. PMID:38740778. at the circuit level, bf glutamatergic neurons make functional contacts with the lateral habenula (lhb) neurons and these connections are potentiated in conditioned mice. 2024-05-13 2024-05-27 mouse
Luqiang Sun, Haichuan Wan. Acupuncture in the treatment of cocaine addiction: how does it work? Acupuncture in medicine : journal of the British Medical Acupuncture Society. 2024-05-06. PMID:38706189. moreover, acupuncture alleviates cocaine-induced seizures or acute psychomotor responses through the paraventricular thalamus and the lateral habenula (lhb)-rostromedial tegmental (rmtg) nucleus circuits. 2024-05-06 2024-05-08 Not clear
Dan Huang, Yunhui Fan, Jingjun Zhang, Qianfeng Wang, Ming Ding, Ruiqing Hou, Kewei Yu, Xiao Xiao, Yi Wu, Junfa W. Dorsal dentate gyrus mediated enriched environment-induced anxiolytic and antidepressant effects in cortical infarcted mice. Experimental neurology. 2024-04-30. PMID:38685308. compared to the mice housing in a standard environment, those subjected to acute ee stimulation had significantly increased alff and reho values in the bilateral somatosensory cortex (s1, s2), dorsal dentate gyrus (ddg), dorsal ca1 of hippocampus (dca1), lateral habenular nucleus (lhb), periaqueductal gray (pag), ipsilateral primary motor cortex (m1), retrosplenial cortex (rsc), parietal association cortex (pta), dorsal ca3 of hippocampus (dca3), claustrum (cl), ventral pallidum (vp), amygdala (amy), and contralateral auditory cortex (au). 2024-04-30 2024-05-03 mouse
Hongren Huang, Xue Liu, Liping Wang, Feng Wan. Whole-brain connections of glutamatergic neurons in the mouse lateral habenula in both sexes. Biology of sex differences. vol 15. issue 1. 2024-04-23. PMID:38654275. the lateral habenula (lhb) is an epithalamus nucleus that is evolutionarily conserved and involved in various physiological functions, such as encoding value signals, integrating emotional information, and regulating related behaviors. 2024-04-23 2024-04-26 mouse
In-Beom Jin, Nam-Heon Kim, Jung-Soo Ha. Emerging role of the lateral habenula in conditioned inhibition and depression. Behavioral neuroscience. 2024-04-18. PMID:38635178. recent research has shed light on the lateral habenula (lhb) engagement in conditioned inhibition, along with the midbrain dopaminergic neurons. 2024-04-18 2024-04-20 Not clear