| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Zhukovskaya, Christopher A Zimmerman, Lindsay Willmore, Alejandro Pan-Vazquez, Sanjeev R Janarthanan, Laura A Lynch, Annegret L Falkner, Ilana B Witte. Heightened lateral habenula activity during stress produces brainwide and behavioral substrates of susceptibility. Neuron. 2024-10-11. PMID:39393349. |
here, we seek to determine if activity in the lateral habenula (lhb), which encodes a negative teaching signal, differs between susceptible and resilient mice during stress to produce different outcomes. |
2024-10-11 |
2024-10-14 |
mouse |
| Zhuojun Kang, Zhenzhen Zheng, Wenli Gu. Efficacy of agomelatine on sleep disorders and lateral habenula neuronal activity in chronic restraint stress depression model mice. Psychopharmacology. 2024-09-09. PMID:39249500. |
this article aimed to explore the effect of agomelatine (ago) on sd in chronic restraint stress (crs) depression model mice and its effect on the activity of neurons in the lateral habenula (lhb). |
2024-09-09 |
2024-09-11 |
mouse |
| Zhiping Cao, Wing-Ho Yung, Ya K. Distinct populations of lateral preoptic nucleus neurons jointly contribute to depressive-like behaviors through divergent projections in male mice. Neurobiology of stress. vol 32. 2024-09-05. PMID:39233784. |
in this study, we discovered that distinct lpo excitatory neurons project separately to the aversive processing center lateral habenula (lhb) and the reward processing hub ventral tegmental area (vta). |
2024-09-05 |
2024-09-08 |
mouse |
| Jose Cesar Hernandez Silva, Nikola Pausic, Arturo Marroquin Rivera, Benoît Labonté, Christophe D Proul. Chronic social defeat stress induces pathway-specific adaptations at lateral habenula neuronal outputs. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-08-20. PMID:39164106. |
the lateral habenula (lhb) has emerged as a pivotal brain region implicated in depression, displaying hyperactivity in human and animal models of depression. |
2024-08-20 |
2024-08-23 |
mouse |
| Eun-Kyung Hwang, Agustin Zapata, Vivian Hu, Alexander F Hoffman, Hui-Ling Wang, Bing Liu, Marisela Morales, Carl R Lupic. Basal forebrain-lateral habenula inputs and control of impulsive behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-08-18. PMID:39155312. |
we previously reported that intact lateral habenula (lhb) function is necessary to limit impulsivity defined by impaired response inhibition in rats. |
2024-08-18 |
2024-08-21 |
rat |
| Ruxuan Ding, Ying Tang, Guoxin Cao, Yunlin Mai, Yixin Fu, Zhiheng Ren, Wenfu Li, Jiawei Hou, Shizhu Sun, Bingqing Chen, Xiaojiao Han, Zelei He, Jianghong Ye, Lihua Zhou, Rao F. Lateral habenula IL-10 controls GABA Brain, behavior, and immunity. 2024-08-11. PMID:39128573. |
the lateral habenula (lhb) encodes aversive experiences, contributes to negative moods, and is pivotal in depression development. |
2024-08-11 |
2024-08-14 |
mouse |
| Dana Cobb-Lewis, Anne George, Shannon Hu, Katherine Packard, Mingyuan Song, Isabellah Nikitah, Oliver Nguyen-Lopez, Emily Tesone, Jhanay Rowden, Julie Wang, Maya Openda. The lateral habenula integrates age and experience to promote social transitions in developing rats. Cell reports. vol 43. issue 8. 2024-08-03. PMID:39096491. |
the lateral habenula (lhb), a highly conserved brain region with consistent links to adult psychopathology, is understudied in development, when the brain is most vulnerable to environmental impacts. |
2024-08-03 |
2024-08-06 |
rat |
| William J Flerlage, Sarah C Simmons, Emily H Thomas, Shawn Gouty, Brian M Cox, Fereshteh S Nugen. Dysregulation of kappa opioid receptor neuromodulation of lateral habenula synaptic function following a repetitive mild traumatic brain injury. Pharmacology, biochemistry, and behavior. 2024-07-27. PMID:39067532. |
the lateral habenula (lhb) plays an important role in pathophysiology of psychiatric disorders. |
2024-07-27 |
2024-08-02 |
mouse |
| Anna Zhukovskaya, Zimmerman Christopher, Lindsay Willmore, Alejandro Pan Vazquez, Sanjeev Janarthanan, Annegret Falkner, Ilana Witte. Heightened lateral habenula activity during stress produces brainwide and behavioral substrates of susceptibility. bioRxiv : the preprint server for biology. 2024-07-15. PMID:39005438. |
here, we seek to determine if activity in the lateral habenula (lhb), which encodes a negative teaching signal, differs between susceptible and resilient mice during stress to produce different outcomes. |
2024-07-15 |
2024-07-18 |
mouse |
| Yuanyuan Tian, Junqiang Zheng, Xiao Zhu, Xue Liu, Haoyang Li, Jun Wang, Qian Yang, Ling-Hui Zeng, Zhiguo Shi, Mengyuan Gong, Yuzheng Hu, Han X. A prefrontal-habenular circuitry regulates social fear behaviour. Brain : a journal of neurology. 2024-07-04. PMID:38963812. |
employing a social fear conditioning paradigm, we induced robust social fear in mice and found that the lateral habenula (lhb) neurons and lhb-projecting mpfc neurons are synchronously activated during social fear expression. |
2024-07-04 |
2024-07-11 |
mouse |
| Xue-Zhong Cao, Meng-Ye Zhu, Gang Xu, Fan Li, Yi Yan, Jin-Jin Zhang, Jianbing Wang, Fei Zeng, Yang Bao, Xue-Xue Zhang, Tao Liu, Da-Ying Zhan. HCN channels in the lateral habenula regulate pain and comorbid depressive-like behaviors in mice. CNS neuroscience & therapeutics. vol 30. issue 7. 2024-07-03. PMID:38961317. |
comorbid anxiodepressive-like symptoms (cads) in chronic pain are closely related to the overactivation of the lateral habenula (lhb). |
2024-07-03 |
2024-07-08 |
mouse |
| Hiroyuki Ichijo, Nguyen Thi Van Trang, Tomoya Nakamur. Topographic Organization of Glutamatergic and GABAergic Parvalbumin Positive Neurons in the Lateral Habenula. eNeuro. 2024-07-03. PMID:38960707. |
parvalbumin-expressing (pv) neurons, classified by their expression of the calcium-binding protein parvalbumin, play crucial roles in the function and plasticity of the lateral habenular nucleus (lhb). |
2024-07-03 |
2024-07-10 |
mouse |
| Nur Abdel-Hay, Marina Kabirova, Rami Yak. A discrete subpopulation of PFC-LHb neurons govern cocaine place preference. Translational psychiatry. vol 14. issue 1. 2024-07-02. PMID:38956048. |
the pfc also projects to the lateral habenula (lhb), a brain region critical for encoding negative reward and regulating the reward system. |
2024-07-02 |
2024-07-06 |
Not clear |
| Yingqing Wu, Jia Deng, Jinsong Ma, Yujie Chen, Ning Hu, Shilei Hao, Bochu Wan. Unraveling the Pathogenesis of Post-Stroke Depression in a Hemorrhagic Mouse Model through Frontal Lobe Circuitry and JAK-STAT Signaling. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024-07-01. PMID:38946585. |
it is demonstrated that depression is a specific neurological complication in the unilateral hematoma model of the mpfc, and the ventral tegmental area (vta) shows a higher percentage of connectivity disruption compared to the lateral habenula (lhb) and striatum (str). |
2024-07-01 |
2024-07-03 |
mouse |
| William J Flerlage, Sarah C Simmons, Emily H Thomas, Shawn Gouty, Mumeko C Tsuda, T John Wu, Regina C Armstrong, Brian M Cox, Fereshteh Nugen. Effects of Repetitive Mild Traumatic Brain Injury on Corticotropin-Releasing Factor Modulation of Lateral Habenula Excitability and Motivated Behavior. Journal of neurotrauma. 2024-06-29. PMID:38943284. |
recent evidence from our laboratory suggests a possible dysregulation within reward/motivational circuit function at the level of a subcortical structure, the lateral habenula (lhb), where we demonstrated a causal role for hyperactive lhb in mtbi-induced motivational deficits in self-care grooming behavior in young adult male mice when exposed to mtbi injury during late adolescence (at ~8 weeks old). |
2024-06-29 |
2024-07-02 |
mouse |
| Zehui Zhang, Wei Zhang, Yuanyuan Fang, Na Wang, Guoying Liu, Nan Zou, Zhenbo Song, Hanshu Liu, Longshuo Wang, Qin Xiao, Juanjuan Zhao, Yaling Wang, Ting Lei, Cai Zhang, Xiaofeng Liu, Beilin Zhang, Fenlan Luo, Jianxia Xia, Chao He, Zhian Hu, Shuancheng Ren, Hua Zha. A potentiation of REM sleep-active neurons in the lateral habenula may be responsible for the sleep disturbance in depression. Current biology : CB. 2024-06-29. PMID:38944036. |
psychiatric disorders with dysfunction of the lateral habenula (lhb) show sleep disturbance, especially a disinhibition of rapid eye movement (rem) sleep in major depression. |
2024-06-29 |
2024-07-02 |
mouse |
| Hailan Liu, Na Qu, Natalia Valdez Gonzalez, Marco A Palma, Huamin Chen, Jiani Xiong, Abhinav Choubey, Yongxiang Li, Xin Li, Meng Yu, Hesong Liu, Longlong Tu, Nan Zhang, Na Yin, Kristine Marie Conde, Mengjie Wang, Jonathan Carter Bean, Junying Han, Nikolas Anthony Scarcelli, Yongjie Yang, Kenji Saito, Huxing Cui, Qingchun Tong, Zheng Sun, Chunmei Wang, Xing Cai, Li Lu, Yang He, Yong X. A light-responsive neural circuit suppresses feeding. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-06-19. PMID:38897723. |
we further show that lateral habenula (lhb) neurons in mice respond to light exposure, which in turn activates 5-ht neurons in the dorsal raphe nucleus (drn). |
2024-06-19 |
2024-06-22 |
mouse |
| Xianwei Liu, Han Li, Ruijia Ma, Xiaohan Tong, Jijin Wu, Xiaodan Huang, Kwok-Fai So, Qian Tao, Lu Huang, Song Lin, Chaoran Re. Burst firing in Output-Defined Parallel Habenula Circuit Underlies the Antidepressant Effects of Bright Light Treatment. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024-06-12. PMID:38863324. |
research highlights the significance of increased bursting in lateral habenula (lhb) neurons in depression and as a focal point for bright light treatment (blt). |
2024-06-12 |
2024-06-14 |
Not clear |
| Kaihua Ma, Huaguang Gu, Yanbing Ji. The neuronal and synaptic dynamics underlying post-inhibitory rebound burst related to major depressive disorder in the lateral habenula neuron model. Cognitive neurodynamics. vol 18. issue 3. 2024-06-03. PMID:38826643. |
a burst behavior observed in the lateral habenula (lhb) neuron related to major depressive disorder has attracted much attention. |
2024-06-03 |
2024-06-05 |
Not clear |
| Hoyong Park, Hakyun Ryu, Seungjae Zhang, Jeehae Rhee, ChiHye Chun. Mu-opioid receptor activation in the habenula modulates synaptic transmission and depression-like behaviors. Neurobiology of disease. 2024-05-31. PMID:38821376. |
first, we found that mor activation decreased both excitatory and inhibitory synaptic transmission onto the lateral habenula (lhb). |
2024-05-31 |
2024-06-02 |
rat |